Phase 1 Study of Topical Perillyl Alcohol Cream for Chemoprevention of Skin Cancer

REFERENCES

• Gould , M N . 1997 . Cancer chemoprevention and therapy by monoterpenes . Environ Health Perspect , 105 ( Suppl4 ) : 977 – 979 .
   PubMedGoogle Scholar
• Barthelman , M , Chen , W , Gensler , H L , Huang , C Dong , Z . 1998 . Inhibitory effects of perillyl alcohol on UVB-induced murine skin cancer and AP-1 transactivation . Cancer Res , 58 : 711 – 716 .
   PubMed Web of Science ®Google Scholar
• Lluria-Prevatt , M , Morreale , J , Gregus , J , Alberts , D S Kaper , F . 2002 . Effects of perillyl alcohol on melanoma in the TPras mouse model . Cancer Epidemiol Biomarkers Prev , 11 : 573 – 579 .
   PubMedGoogle Scholar
• Mills , J J , Chari , R S , Boyer , I J , Gould , M N and Jirtle , R L . 1995 . Induction of apoptosis in liver tumors by the monoterpene perillyl alcohol . Cancer Res , 55 : 979 – 983 .
   PubMed Web of Science ®Google Scholar
• Crowell , P L . 1999 . Prevention and therapy of cancer by dietary monoterpenes . J Nutr , 129 : 775S – 778S .
   PubMed Web of Science ®Google Scholar
• Hohl , R J and Lewis , K . 1995 . Differential effects of monoterpenes and lovastatin on RAS processing . J Biol Chem , 270 : 17508 – 17512 .
   PubMedGoogle Scholar
• Ripple , G H , Gould , M N , Arzoomanian , R Z , Alberti , D Feierabend , C . 2000 . Phase I clinical and pharmacokinetic study of perillyl alcohol administered four times a day . Clin Cancer Res , 6 : 390 – 396 .
   PubMed Web of Science ®Google Scholar
• Hakim , I A , Harris , R B and Ritenbaugh , C . 2000 . Citrus peel use is associated with reduced risk of squamous cell carcinoma of the skin . Nutr Cancer , 37 : 161 – 168 .
   PubMed Web of Science ®Google Scholar
• Gupta , A and Myrdal , P B . 2004 . Development of a perillyl alcohol topical cream formulation . Int J Pharm , 269 : 373 – 383 .
   PubMed Web of Science ®Google Scholar
• Gupta , A , Stratton , S P and Myrdal , P B . 2005 . An HPLC method for quantitation of perillyl alcohol in a topical pharmaceutical cream formulation . J Pharm Biomed Anal , 37 : 447 – 452 .
   PubMedGoogle Scholar
• Bozzo , P , Saboda , K , Einspahr , J G , Ranger-Moore , J Farmer , E R . 2003 . Reliability and validity of a histologic score as a marker for skin cancer chemoprevention studies . Anal Quant Cytol Histol , 25 : 285 – 292 .
   PubMedGoogle Scholar
• Plewis , I . 1985 . “ Ways of measuring change ” . In Analyzing Change: Measurement and Explanations Using Longitudinal Data , 16 – 29 . New York : Wiley & Sons, Inc. .
   Google Scholar
• Marks , R . 1995 . An overview of skin cancers: incidence and causation . Cancer , 75 : 607 – 612 .
   PubMed Web of Science ®Google Scholar
• U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health, National Cancer Institute . 2003 . Cancer Progress Report 2003 Update , Bethesda, MD : National Institutes of Health . (NIH Publication No. 02 - 5045)
   Google Scholar
• Burren , R , Scaletta , C , Frenk , E , Panizzon , R G and Applegate , L A . 1998 . Sunlight and carcinogenesis: expression of p53 and pyrimidine dimers in human skin following UVA I, UVA I + II and solar simulating radiations . Int J Cancer , 76 : 201 – 206 .
   PubMed Web of Science ®Google Scholar
• de Gruijl , F R . 2000 . Photocarcinogenesis: UVA vs. UVB . Methods Enzymol , 319 : 359 – 366 .
   PubMed Web of Science ®Google Scholar
• Runger , T M . 1999 . Role of UVA in the pathogenesis of melanoma and non-melanoma skin cancer: a short review . Photodermatol Photoimmunol Photomed , 15 : 212 – 216 .
   PubMed Web of Science ®Google Scholar
• Swerdlow , A J and Weinstock , M A . 1998 . Do tanning lamps cause melanoma? an epidemiologic assessment . J Am Acad Dermatol , 38 : 89 – 98 .
   PubMed Web of Science ®Google Scholar