Caffeine Overcomes Genistein-Induced G2/M Cell Cycle Arrest in Breast Cancer Cells

REFERENCES

• Peterson , G and Barnes , S . 1991 . Genistein inhibition of the growth of human breast cancer cells: independence from estrogen receptors and the multi-drug resistance gene . Biochem Biophys Res Commun , 179 : 661 – 667 .
   PubMed Web of Science ®Google Scholar
• Fotsis , T , Pepper , M , Adlercreutz , H , Hase , T Montesano , R . 1995 . Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis . J Nutr , 125 : 790S – 797S .
   PubMed Web of Science ®Google Scholar
• Zhou , J R , Mukherjee , P , Gugger , E T , Tanaka , T Blackburn , G L . 1998 . Inhibition of murine bladder tumorigenesis by soy isoflavones via alterations in the cell cycle, apoptosis, and angiogenesis . Cancer Res , 58 : 5231 – 5238 .
   PubMed Web of Science ®Google Scholar
• Messina , M J , Persky , V , Setchell , K D and Barnes , S . 1994 . Soy intake and cancer risk: a review of the in vitro and in vivo data . Nutr Cancer , 21 : 115 – 131 .
   Google Scholar
• Shao , Z M , Wu , J , Shen , Z Z and Barsky , S H . 1998 . Genistein exerts multiple suppressive effects on human breast carcinoma cells . Cancer Res , 58 : 4851 – 4857 .
   PubMed Web of Science ®Google Scholar
• Peterson , G . 1995 . Evaluation of the biochemical targets of genistein in tumor cells . J Nutr , 125 : 784S – 789S .
   PubMed Web of Science ®Google Scholar
• Spinozzi , F , Pagliacci , M C , Migliorati , G , Moraca , R Grignani , F . 1994 . The natural tyrosine kinase inhibitor genistein produces cell cycle arrest and apoptosis in Jurkat T-leukemia cells . Leuk Res , 18 : 431 – 439 .
   PubMed Web of Science ®Google Scholar
• Sherr , C J . 1996 . Cancer cell cycle . Science , 274 : 1672 – 1677 .
   PubMed Web of Science ®Google Scholar
• Traganos , F , Ardelt , B , HaJko , N , Bruno , S and Darzynkiewicz , Z . 1992 . Effects of genistein on the growth and cell cycle progression of normal human lymphocytes and human leukemic MOLT-4 and HL-60 cells . Cancer Res , 52 : 6200 – 6208 .
   PubMed Web of Science ®Google Scholar
• Choi , Y H , Zhang , L , Lee , W H and Park , K Y . 1998 . Genistein-induced G2/M arrest is associated with the inhibition of cyclin B1 and the induction of p21 in human breast carcinoma cells . Int J Oncol , 13 : 391 – 396 .
   PubMed Web of Science ®Google Scholar
• Luo , Y , Rockow-Magnone , S K , Joseph , M K , Bradner , J Butler , C C . 2001 . Abrogation of G2 checkpoint specifically sensitize p53 defective cells to cancer chemotherapeutic agents . Anticancer Res , 21 : 23 – 28 .
   PubMedGoogle Scholar
• Cailleau , R , Olive , M and Cruciger , Q V . 1978 . Long-term human breast carcinoma cell lines of metastatic origin: preliminary characterization . In Vitro , 14 : 911 – 915 .
   PubMedGoogle Scholar
• Ross , D T , Scherf , U , Eisen , M B , Perou , C M Rees , C . 2000 . Systematic variation in gene expression patterns in human cancer cell lines . Nat Genet , 24 : 227 – 235 .
   PubMed Web of Science ®Google Scholar
• Rae , J M , Creighton , C J , Meck , J M , Haddad , B R and Johnson , M D . 2007 . MDA-MB-435 cells are derived from M14 melanoma cells—a loss for breast cancer, but a boon for melanoma research . Breast Cancer Res Treat , 104 : 13 – 19 .
   PubMed Web of Science ®Google Scholar
• Sellappan , S , Grijalva , R , Zhou , X Y , Yang , W T Eli , M B . 2004 . Lineage infidelity of MDA-MB-435 Cells: expression of melanocyte proteins in a breast cancer cell line . Cancer Res , 64 : 3479 – 3485 .
   PubMed Web of Science ®Google Scholar
• Chang , K L , Kung , M L , Chow , N H and Su , S J . 2004 . Genistein arrests hepatoma cells at G2/M phase: involvement of ATM activation and upregulation of p21waf1/cip1 and Wee1 . Biochem Pharmacol , 67 : 717 – 726 .
   PubMed Web of Science ®Google Scholar
• Matsukawa , Y , Marui , N , Sakai , T , Satomi , Y Yoshida , M . 1993 . Genistein arrests cell cycle progression at G2-M . Cancer Res , 53 : 1328 – 1331 .
   PubMed Web of Science ®Google Scholar
• Nomoto , S , Arao , Y , Horiguchi , H , Ikeda , K and Kayama , F . 2002 . Oestrogen causes G2/M arrest and apoptosis in breast cancer cells MDA-MB-231 . Oncol Rep , 9 : 773 – 776 .
   PubMedGoogle Scholar
• Kobayashi , T , Nakata , T and Kuzumaki , T . 2002 . Effect of flavonoids on cell cycle progression in prostate cancer cells . Cancer Lett , 176 : 17 – 23 .
   PubMed Web of Science ®Google Scholar
• Frey , R S , Li , J and Singletary , K W . 2001 . Effects of genistein on cell proliferation and cell cycle arrest in nonneoplastic human mammary epithelial cells: involvement of Cdc2, p21waf/cip1, p27kip1, and Cdc25C expression . Biochem Pharmacol , 61 : 979 – 989 .
   PubMed Web of Science ®Google Scholar
• Lian , F , Bhuiyan , M , Li , Y W , Wall , N Kraut , M . 1998 . Genistein-induced G2-M arrest, p21WAF1 upregulation, and apoptosis in a non-small-cell lung cancer cell line . Nutr Cancer , 31 : 184 – 191 .
   PubMed Web of Science ®Google Scholar
• Kuzumaki , T , Kobayashi , T and Ishikawa , K . 1998 . Genistein induces p21Cip1/WAF1 expression and blocks the G1 to S phase transition in mouse fibroblast and melanoma cells . Biochem Biophys Res Commun , 251 : 291 – 295 .
   PubMed Web of Science ®Google Scholar
• Flatt , P M and Pietenpol , J A . 2000 . Mechanism of cell-cycle checkpoints: at the crossroads of carcinogenesis and drug discovery . Drug Metab Rev , 32 : 283 – 305 .
   PubMed Web of Science ®Google Scholar
• Yao , S L , Akhtar , A J , McKenna , K A , Bedi , G C Sidransky , D . 1996 . Selective radiosensitization of p53-deficient cells by caffeine-mediated activation of p34cdc2 kinase . Nat Med , 2 : 1140 – 1143 .
   PubMed Web of Science ®Google Scholar
• Bulavin , D V , Higashimoto , Y , Popoff , I J , Gaarde , W A Basrur , V . 200 . Initiation of a G2/M checkpoint after ultraviolet radiation requires p38 kinase . Nature , 411 : 102 – 107 .
   Google Scholar
• Malathi , K , Li , X , Krizanova , O , Ondrias , K Sperber , K . 2005 . Cdc2/cyclin B1 interacts with and modulates inositol 1,4,5-trisphosphate receptor (type 1) functions . J Immunol , 175 : 6205 – 6210 .
   PubMedGoogle Scholar
• Menon , S G and Goswami , P C . 2007 . A redox cycle within the cell cycle: ring in the old with the new . Oncogene , 26 : 1101 – 1109 .
   PubMed Web of Science ®Google Scholar
• Smart , D K , Ortiz , K L , Mattson , D , Bradbury , C M Bisht , K S . 2004 . Thioredoxin reductase as a potential molecular target for anticancer agents that induce oxidative stress . Cancer Res , 64 : 6716 – 6724 .
   PubMed Web of Science ®Google Scholar
• Elder , R T , Yu , M , Chen , M , Zhu , X Yanagida , M . 2001 . HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25 . Virology , 287 : 359 – 370 .
   PubMedGoogle Scholar
• Kikuchi , Y , Kakeya , T , Yamazaki , T , Takekida , K Nakamura , N . 2002 . G1-dependent prion protein expression in human glioblastoma cell line T98G . Biol Pharm Bull , 25 : 728 – 733 .
   PubMedGoogle Scholar
• Ise , R , Han , D , Takahashi , Y , Terasaka , S Inoue , A . 2005 . Expression profiling of the estrogen responsive genes in response to phytoestrogens using a customized DNA microarray . FEBS Lett , 579 : 1732 – 1740 .
   PubMed Web of Science ®Google Scholar
• Abdel-Malek , Z , Swope , V , Smalara , D , Babcock , G Dawes , S . 1995 . Analysis of the UV-induced melanogenesis and growth arrest of human melanocytes . Pigment Cell Res , 7 : 326 – 332 .
   Google Scholar