177
Views
40
CrossRef citations to date
0
Altmetric
Original Articles

Combination Chemoprevention of Intestinal Carcinogenesis in a Murine Model of Familial Adenomatous Polyposis

, , , , &
Pages 30-35 | Received 11 Aug 2008, Accepted 11 Aug 2008, Published online: 10 Nov 2008

REFERENCES

  • Fodde , R . 2002 . The APC gene in colorectal cancer . Eur J Cancer , 38 : 867 – 371 .
  • Jass , J R . 2000 . Familial colorectal cancer: pathology and molecular characteristics . Lancet Oncol , 1 : 220 – 226 .
  • Cetta , F and Dhamo , A . 2007 . Inherited multitumoral syndromes including colorectal carcinoma . Surg Oncol , 16 ( 1 Suppl ) : S17 – S23 .
  • Steinbach , G , Lynch , P M , Phillips , R K , Wallace , M H Hawk , E . 2000 . The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis . N Engl J Med , 342 : 1946 – 1952 .
  • Giardiello , F M , Yang , V W , Hylind , L M , Krush , A J Petersen , G M . 2002 . Primary chemoprevention of familial adenomatous polyposis with sulindac . N Engl J Med , 346 : 1054 – 1059 .
  • Gill , S and Sinicrope , F A . 2005 . Colorectal cancer prevention: is an ounce of prevention worth a pound of cure? . Sem Oncol , 32 : 24 – 34 .
  • Su , L K , Kinzler , K W , Vogelstein , B , Preisinger , A C Moser , A R . 1992 . Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene . Science , 256 : 668 – 670 .
  • Moser , A R , Pitot , H C and Dove , W F . 1990 . A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse . Science , 247 : 322 – 324 .
  • Jacoby , R F , Cole , C E , Tutsch , K , Newton , M A Kelloff , G . 2000 . Chemopreventive efficacy of combined piroxicam and difluoromethylornithine treatment of Apc mutant Min mouse adenomas, and selective toxicity against Apc mutant embryos . Cancer Res , 60 : 1864 – 1870 .
  • Zell , J A , Ignatenko , N A , Yerushalmi , H F , Ziogas , A Besselsen , D G . 2007 . Risk and risk reduction involving arginine intake and meat consumption in colorectal tumorigenesis and survival . Int J Cancer , 120 : 459 – 468 .
  • Meyskens , F LJ , McLaren , C E , Pelot , D , Fujikawa-Brooks , S Carpenter , P M . 2008 . Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: a randomized placebo controlled, double-blind trial . Cancer Prev Res , 1 : 32 – 38 .
  • Baron , J A , Cole , B F , Sandler , R S , Haile , R W Ahnen , D . 2003 . A randomized trial of aspirin to prevent colorectal adenomas . N Engl J Med , 348 : 891 – 899 .
  • Arber , N , Eagle , C J , Spicak , J , Racz , I Dite , P . 2006 . Celecoxib for the prevention of colorectal adenomatous polyps . N Engl J Med , 355 : 885 – 895 .
  • Bertagnolli , M M , Eagle , C J , Zauber , A G , Redston , M Solomon , S D . 2006 . Celecoxib for the prevention of sporadic colorectal adenomas . N Engl J Med , 355 : 873 – 884 .
  • Babbar , N , Ignatenko , N A , Casero , R A Jr and Gerner , E W . 2003 . Cyclooxygenase-independent induction of apoptosis by sulindac sulfone is mediated by polyamines in colon cancer . J Biol Chem , 278 : 47762 – 47775 .
  • Ignatenko , N A , Besselsen , D G , Roy , U K , Stringer , D E Blohm-Mangone , K A . 2006 . Dietary putrescine reduces the intestinal anticarcinogenic activity of sulindac in a murine model of familial adenomatous polyposis . Nutr Cancer , 56 : 172 – 181 .
  • Gerner , E W and Meyskens , F L Jr . 2004 . Polyamines and cancer: old molecules, new understanding . Nat Rev Cancer , 4 : 781 – 792 .
  • Dietrich , W F , Lander , E S , Smith , J S , Moser , A R Gould , K A . 1993 . Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse . Cell , 75 : 631 – 639 .
  • Erdman , S H , Ignatenko , N A , Powell , M B , Blohm-Mangone , K A Holubec , H . 1999 . APC-dependent changes in expression of genes influencing polyamine metabolism, and consequences for gastrointestinal carcinogenesis, in the Min mouse . Carcinogenesis , 20 : 1709 – 1713 .
  • Zell , J A , Yerushalmi , H F , Ignatenko , N A , Besselsen , D E Ziogas , A . 2007 . Non-steroidal anti-inflammatory drugs and arginine intake in colorectal tumorigenesis and survival . Int J Cancer , 120 : 459 – 468 .
  • Rao , C V , Rivenson , A , Simi , B , Zang , E Kelloff , G . 1995 . Chemoprevention of colon carcinogenesis by sulindac, a nonsteroidal anti-inflammatory agent . Cancer Res , 55 : 1464 – 1472 .
  • Jacoby , R F , Seibert , K , Cole , C E , Kelloff , G and Lubet , R A . 2000 . The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis . Cancer Res , 60 : 5040 – 5044 .
  • Saukkonen , K , Tomasetto , C , Narko , K , Rio , M C and Ristimaki , A . 2003 . Cyclooxygenase-2 expression and effect of celecoxib in gastric adenomas of trefoil factor 1-deficient mice . Cancer Res , 63 : 3032 – 3036 .
  • Seiler , N and Knodgen , B . 1980 . High-performance liquid chromatography procedure for the simultaneous determination of the natural polyamines and their monoacetylderivatives . J Chromatog , 221 : 227 – 238 .
  • Boivin , G P , Washington , K , Yang , K , Ward , J M Pretlow , T P . 2003 . Pathology of mouse models of intestinal cancer: consensus report and recommendations . Gastroenterology , 124 : 762 – 777 .
  • Arber , N and Levin , B . 2008 . Chemoprevention of colorectal neoplasia: the potential for personalized medicine . Gastroenterology , 134 : 1224 – 1237 .
  • Lance , P . 2008 . Chemoprevention for colorectal cancer: some progress but a long way to go . Gastroenterology , 134 : 341 – 343 .
  • Boolbol , S K , Dannenberg , A J , Chadburn , A , Martucci , C Guo , X J . 1996 . Cyclooxygenase-2 overexpression and tumor formation are blocked by sulindac in a murine model of familial adenomatous polyposis . Cancer Res , 56 : 2556 – 2560 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.