Chemopreventive Effects of the Standardized Extract (DA-9601) of Artemisia asiatica on Azoxymethane-Initiated and Dextran Sulfate Sodium-Promoted Mouse Colon Carcinogenesis

REFERENCES

• Tanaka , T , Kohno , H , Suzuki , R , Yamada , Y Sugie , S . 2003 . A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate . Cancer Sci , 94 : 965 – 973 .
   PubMed Web of Science ®Google Scholar
• Watanabe , K , Kawamori , T , Nakatsugi , S and Wakabayashi , K . 2000 . COX-2 and iNOS, good targets for chemoprevention of colon cancer . Biofactors , 12 : 129 – 133 .
   PubMed Web of Science ®Google Scholar
• Prescott , S M and Fitzpatrick , F A . 2000 . Cyclooxygenase-2 and carcinogenesis . Biochim Biophys Acta , 1470 : M69 – 78 .
   PubMed Web of Science ®Google Scholar
• Oshima , M , Dinchuk , J E , Kargman , S L , Oshima , H Hancock , B . 1996 . Suppression of intestinal polyposis in Apcdelta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2) . Cell , 87 : 803 – 809 .
   PubMed Web of Science ®Google Scholar
• Steinbach , G , Lynch , P M , Phillips , R K , Wallace , M H Hawk , E . 2000 . The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis . N Engl J Med , 342 : 1946 – 1952 .
   PubMed Web of Science ®Google Scholar
• Rao , C V . 2004 . Nitric oxide signaling in colon cancer chemoprevention . Mutat Res , 555 : 107 – 119 .
   PubMed Web of Science ®Google Scholar
• Karin , M and Greten , F R . 2005 . NF-κ B: linking inflammation and immunity to cancer development and progression . Nat Rev Immunol , 5 : 749 – 759 .
   PubMed Web of Science ®Google Scholar
• Schreiber , S , Nikolaus , S and Hampe , J . 1998 . Activation of nuclear factor-κ B inflammatory bowel disease . Gut , 42 : 477 – 484 .
   PubMed Web of Science ®Google Scholar
• Broom , O J , Massoumi , R and Sjolander , A . 2006 . Alpha2beta1 integrin signalling enhances cyclooxygenase-2 expression in intestinal epithelial cells . J Cell Physiol , 209 : 950 – 958 .
   PubMed Web of Science ®Google Scholar
• Kojima , M , Morisaki , T , Izuhara , K , Uchiyama , A Matsunari , Y . 2000 . Lipopolysaccharide increases cyclooxygenase-2 expression in a colon carcinoma cell line through nuclear factor-kappa B activation . Oncogene , 19 : 1225 – 1231 .
   PubMed Web of Science ®Google Scholar
• Chun , K S , Keum , Y S , Han , S S , Song , Y S Kim , S H . 2003 . Curcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NF-κB activation . Carcinogenesis , 24 : 1515 – 1524 .
   PubMed Web of Science ®Google Scholar
• Nakano , H , Shindo , M , Sakon , S , Nishinaka , S Mihara , M . 1998 . Differential regulation of Iκ B kinase alpha and beta by two upstream kinases, NF-κ B-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1 . Proc Natl Acad Sci USA , 95 : 3537 – 3542 .
   PubMed Web of Science ®Google Scholar
• Kim , S O , Kundu , J K , Shin , Y K , Park , J H Cho , M H . 2005 . [6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-κB in phorbol ester-stimulated mouse skin . Oncogene , 24 : 2558 – 2567 .
   PubMed Web of Science ®Google Scholar
• Howes , L G . 2007 . Selective COX-2 inhibitors, NSAIDs and cardiovascular events—is celecoxib the safest choice? . Ther Clin Risk Manag , 3 : 831 – 845 .
   PubMedGoogle Scholar
• Roumie , C L , Mitchel , E F Jr , Kaltenbach , L , Arbogast , P G Gideon , P . 2008 . Nonaspirin NSAIDs, cyclooxygenase 2 inhibitors, and the risk for stroke . Stroke , 39 : 2037 – 2045 .
   PubMed Web of Science ®Google Scholar
• Solomon , D H , Avorn , J , Sturmer , T , Glynn , R J Mogun , H . 2006 . Cardiovascular outcomes in new users of coxibs and nonsteroidal antiinflammatory drugs: high-risk subgroups and time course of risk . Arthritis Rheum , 54 : 1378 – 1389 .
   PubMed Web of Science ®Google Scholar
• Surh , Y-J . 2003 . Cancer chemoprevention with dietary phytochemicals . Nat Rev Cancer , 3 : 768 – 780 .
   PubMed Web of Science ®Google Scholar
• Seo , H J , Park , K K , Han , S S , Chung , W Y Son , M W . 2002 . Inhibitory effects of the standardized extract (DA-9601) of Artemisia asiatica Nakai on phorbol ester-induced ornithine decarboxylase activity, papilloma formation, cyclooxygenase-2 expression, inducible nitric oxide synthase expression and nuclear transcription factor kappa B activation in mouse skin . Int J Cancer , 100 : 456 – 462 .
   PubMedGoogle Scholar
• Lee , J S , Oh , T Y , Ahn , B O , Cho , H Kim , W B . 2001 . Involvement of oxidative stress in experimentally induced reflux esophagitis and Barrett's esophagus: clue for the chemoprevention of esophageal carcinoma by antioxidants . Mutat Res , 480–481 : 189 – 200 .
   PubMed Web of Science ®Google Scholar
• Suzuki , R , Kohno , H , Sugie , S and Tanaka , T . 2005 . Dose-dependent promoting effect of dextran sodium sulfate on mouse colon carcinogenesis initiated with azoxymethane . Histol Histopathol , 20 : 483 – 492 .
   PubMed Web of Science ®Google Scholar
• Cooper , H S , Murthy , S , Kido , K , Yoshitake , H and Flanigan , A . 2000 . Dysplasia and cancer in the dextran sulfate sodium mouse colitis model. Relevance to colitis-associated neoplasia in the human: a study of histopathology, β-catenin and p53 expression and the role of inflammation . Carcinogenesis , 21 : 757 – 768 .
   PubMed Web of Science ®Google Scholar
• Kohno , H , Suzuki , R , Sugie , S and Tanaka , T . 2005 . β-Catenin mutations in a mouse model of inflammation-related colon carcinogenesis induced by 1,2-dimethylhydrazine and dextran sodium sulfate . Cancer Sci , 96 : 69 – 76 .
   PubMedGoogle Scholar
• Kundu , J K , Choi , K Y and Surh , Y-J . 2006 . β-Catenin-mediated signaling: a novel molecular target for chemoprevention with anti-inflammatory substances . Biochim Biophys Acta , 1765 : 14 – 24 .
   PubMedGoogle Scholar
• Kundu , J K and Surh , Y-J . 2008 . Inflammation: Gearing the journey to cancer . Mutat Res , 659 : 15 – 30 .
   PubMed Web of Science ®Google Scholar
• Marx , J . 2004 . Cancer research. Inflammation and cancer: the link grows stronger . Science , 306 : 966 – 968 .
   PubMed Web of Science ®Google Scholar
• Inoue , T , Hirata , I and Murano , M . 2008 . Effects of nimesulide, a cyclooxygenase-2 selective inhibitor, on colitis induced tumors . Inflammopharmacology , 16 : 36 – 39 .
   PubMedGoogle Scholar
• Kohno , H , Takahashi , M , Yasui , Y , Suzuki , R Miyamoto , S . 2007 . A specific inducible nitric oxide synthase inhibitor, ONO-1714 attenuates inflammation-related large bowel carcinogenesis in male Apc(Min/+) mice . Int J Cancer , 121 : 506 – 513 .
   PubMed Web of Science ®Google Scholar
• Harris , R E , Beebe-Donk , J and Alshafie , G A . 2007 . Cancer chemoprevention by cyclooxygenase 2 (COX-2) blockade: results of case control studies . Subcell Biochem , 42 : 193 – 212 .
   PubMedGoogle Scholar
• Aggarwal , B B and Shishodia , S . 2006 . Molecular targets of dietary agents for prevention and therapy of cancer . Biochem Pharmacol , 71 : 1397 – 1421 .
   PubMed Web of Science ®Google Scholar
• Kundu , J K and Surh , Y-J . 2005 . Breaking the relay in deregulated cellular signal transduction as a rationale for chemoprevention with anti-inflammatory phytochemicals . Mutat Res , 591 : 123 – 146 .
   PubMed Web of Science ®Google Scholar
• Hahm , K B , Kim , J H , You , B M , Kim , Y S Cho , S W . 1998 . Induction of apoptosis with an extract of Artemisia asiatica attenuates the severity of cerulein-induced pancreatitis in rats . Pancreas , 17 : 153 – 157 .
   PubMed Web of Science ®Google Scholar
• Yoo , B M , Oh , T Y , Kim , Y B , Yeo , M Lee , J S . 2005 . Novel antioxidant ameliorates the fibrosis and inflammation of cerulein-induced chronic pancreatitis in a mouse model . Pancreatology , 5 : 165 – 176 .
   PubMed Web of Science ®Google Scholar
• Kim , J Y , Kim , D Y , Lee , Y S , Lee , B K Lee , K H . 2006 . DA-9601, Artemisia asiatica herbal extract, ameliorates airway inflammation of allergic asthma in mice . Mol Cells , 22 : 104 – 112 .
   PubMedGoogle Scholar
• Oh , T Y , Lee , J S , Ahn , B O , Cho , H Kim , W B . 2001 . Oxidative stress is more important than acid in the pathogenesis of reflux oesophagitis in rats . Gut , 49 : 364 – 371 .
   PubMed Web of Science ®Google Scholar
• Hokari , R , Kato , S , Matsuzaki , K , Kuroki , M Iwai , A . 2001 . Reduced sensitivity of inducible nitric oxide synthase-deficient mice to chronic colitis . Free Radic Biol Med , 31 : 153 – 163 .
   PubMed Web of Science ®Google Scholar
• Pikarsky , E , Porat , R M , Stein , I , Abramovitch , R Amit , S . 2004 . NF-κB functions as a tumor promoter in inflammation-associated cancer . Nature , 431 : 461 – 466 .
   PubMed Web of Science ®Google Scholar
• Murano , M , Maemura , K , Hirata , I , Toshina , K Nishikawa , T . 2000 . Therapeutic effect of intracolonically administered nuclear factor kappa B (p65) antisense oligonucleotide on mouse dextran sulphate sodium (DSS)-induced colitis . Clin Exp Immunol , 120 : 51 – 58 .
   PubMed Web of Science ®Google Scholar
• Hirata , I , Yasumoto , S , Toshina , K , Inoue , T Nishikawa , T . 2007 . Evaluation of the effect of pyrrolidine dithiocarbamate in suppressing inflammation in mice with dextran sodium sulfate-induced colitis . World J Gastroenterol , 13 : 1666 – 1671 .
   PubMed Web of Science ®Google Scholar
• Cheon , J H , Kim , J S , Kim , J M , Kim , N Jung , H C . 2006 . Plant sterol guggulsterone inhibits nuclear factor-κ B signaling in intestinal epithelial cells by blocking IκB kinase and ameliorates acute murine colitis . Inflamm Bowel Dis , 12 : 1152 – 1161 .
   PubMed Web of Science ®Google Scholar
• Kristof , A S , Marks-Konczalik , J and Moss , J . 2001 . Mitogen-activated protein kinases mediate activator protein-1-dependent human inducible nitric-oxide synthase promoter activation . J Biol Chem , 276 : 8445 – 8452 .
   PubMed Web of Science ®Google Scholar
• Lee , J K , Choi , S S , Won , J S and Suh , H W . 2003 . The regulation of inducible nitric oxide synthase gene expression induced by lipopolysaccharide and tumor necrosis factor-α in C6 cells: involvement of AP-1 and NF-κB . Life Sci , 73 : 595 – 609 .
   PubMed Web of Science ®Google Scholar
• Moriyama , I , Ishihara , S , Rumi , M A , Aziz , M D Mishima , Y . 2008 . Decoy oligodeoxynucleotide targeting activator protein-1 (AP-1) attenuates intestinal inflammation in murine experimental colitis . Lab Invest , 88 : 652 – 663 .
   PubMed Web of Science ®Google Scholar
• Schandl , L , Ebert , M P and Malfertheiner , P . 2000 . Cadherins and catenins in inflammation and oncogenesis . Dig Liver Dis , 32 : S184 – S187 .
   Google Scholar