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Original Articles

Low Dietary Inorganic Phosphate Stimulates Lung Tumorigenesis Through Altering Protein Translation and Cell Cycle in K-rasLA1 Mice

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Pages 525-532 | Received 10 Apr 2009, Accepted 27 Oct 2009, Published online: 27 Apr 2010

REFERENCES

  • Takeda , E , Yamamoto , H , Nashiki , K , Sato , T Arai , H . 2004 . Inorganic phosphate homeostasis and the role of dietary phosphorus . J Cell Mol Med , 8 : 191 – 200 .
  • Xu , C X , Jin , H , Lim , H T , Kim , J E Shin , J Y . 2008 . High dietary inorganic phosphate enhances cap-dependent protein translation, cell cycle progression, and angiogenesis in the livers of young mice . Am J Physiol Gastrointest Liver Physiol , 295 : G654 – G663 .
  • Jin , H , Chang , S H , Xu , C X , Shin , J Y Chung , Y S . 2007 . High dietary inorganic phosphate affects lung through altering protein translation, cell cycle, and angiogenesis in developing mice . Toxicol Sci , 100 : 215 – 223 .
  • Jin , H , Hwang , S K , Yu , K , Anderson , H K Lee , Y S . 2006 . A high inorganic phosphate diet perturbs brain growth, alters Akt-ERK signaling, and results in changes in cap-dependent translation . Toxicol Sci , 90 : 221 – 229 .
  • Weiner , M L , Salminen , W F , Larson , P R , Barter , R A Kranetz , J L . 2001 . Toxicological review of inorganic phosphates . Food Chem Toxicol , 39 : 759 – 786 .
  • Jin , H , Xu , C X , Lim , H T , Park , S J Shin , J Y . 2009 . High dietary inorganic phosphate increases lung tumorigenesis and alters Akt signaling . Am J Respir Crit Care Med , 179 : 59 – 68 .
  • Hashimoto , M , Wang , D Y , Kamo , T , Zhu , Y Tsujiuchi , T . 2000 . Isolation and localization of type IIb Na/Pi cotransporter in the developing rat lung . Am J Pathol , 157 : 21 – 27 .
  • Yin , B W , Kiyamova , R , Chua , R , Caballero , O L Gout , I . 2008 . Monoclonal antibody MX35 detects the membrane transporter NaPi2b (SLC34A2) in human carcinomas . Cancer Immun , 8 : 3
  • Tang , J M , He , Q Y , Guo , R X and Chang , X J . 2006 . Phosphorylated Akt overexpression and loss of PTEN expression in non-small cell lung cancer confers poor prognosis . Lung Cancer , 51 : 181 – 191 .
  • Takeda , E , Taketani , Y , Sawada , N , Sato , T and Yamamoto , H . 2004 . The regulation and function of phosphate in the human body . Biofactors , 21 : 345 – 355 .
  • Jin , H , Hwang , S K , Kwon , J T , Lee , Y S An , G H . 2008 . Low dietary inorganic phosphate affects the brain by controlling apoptosis, cell cycle and protein translation . J Nutr Biochem , 19 : 16 – 25 .
  • Malkinson , A M . 2001 . Primary lung tumors in mice as an aid for understanding, preventing, and treating human adenocarcinoma of the lung . Lung Cancer , 32 : 265 – 279 .
  • Johnson , L , Mercer , K , Greenbaum , D , Bronson , R T Crowley , D . 2001 . Somatic activation of the K-ras oncogene causes early-onset lung cancer in mice . Nature , 410 : 1111 – 1116 .
  • Fuller , S A , Takahashi , M and Hurrell , J GG . 2007 . “ Preparation of monoclonal antibodies ” . In Current Protocols in Molecular Biology , Edited by: Ausubel , F M , Brent , R , Kingston , R E , More , D D and Seidman , J G . 11.4.1–.5 New York : Wiley .
  • Zhang , Z , Liu , Q , Lantry , L E , Wang , Y Kelloff , G J . 2000 . A germ-line p53 mutation accelerates pulmonary tumorigenesis: p53-independent efficacy of chemopreventive agents green tea or dexamethasone/myo-inositol and chemotherapeutic agents taxol or adriamycin . Cancer Res , 60 : 901 – 907 .
  • West , K A , Brognard , J , Clark , A S , Linnoila , I R Yang , X . 2003 . Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells . J Clin Invest , 111 : 81 – 90 .
  • Suzuki , O , Kamakura , S , Katagiri , T , Nakamura , M Zhao , B . 2006 . Bone formation enhanced by implanted octacalcium phosphate involving conversion into Ca-deficient hydroxyapatite . Biomaterials , 27 : 2671 – 2681 .
  • Czarnogorski , M , Woda , C B , Schulkin , J and Mulroney , S E . 2004 . Induction of a phosphate appetite in adult male and female rats . Exp Biol Med (Maywood) , 229 : 914 – 919 .
  • Marks , K H , Kilav , R , Berman , E , Naveh-Many , T and Silver , J . 1997 . Parathyroid hormone gene expression in Hyp mice fed a low-phosphate diet . Nephrol Dial Transplant , 12 : 1581 – 1585 .
  • Ohnishi , R , Segawa , H , Kawakami , E , Furutani , J Ito , M . 2007 . Control of phosphate appetite in young rats . J Med Invest , 54 : 366 – 369 .
  • Caverzasio , J and Bonjour , J P . 1996 . Characteristics and regulation of Pi transport in osteogenic cells for bone metabolism . Kidney Int , 49 : 975 – 980 .
  • Hattenhauer , O , Traebert , M , Murer , H and Biber , J . 1999 . Regulation of small intestinal Na-P(i) type IIb cotransporter by dietary phosphate intake . Am J Physiol , 277 : G756 – G762 .
  • Loghman-Adham , M . 1997 . Adaptation to changes in dietary phosphorus intake in health and in renal failure . J Lab Clin Med , 129 : 176 – 188 .
  • Perwad , F , Azam , N , Zhang , M Y , Yamashita , T Tenenhouse , H S . 2005 . Dietary and serum phosphorus regulate fibroblast growth factor 23 expression and 1,25-dihydroxyvitamin D metabolism in mice . Endocrinology , 146 : 5358 – 5364 .
  • Traebert , M , Hattenhauer , O , Murer , H , Kaissling , B and Biber , J . 1999 . Expression of type II Na-P(i) cotransporter in alveolar type II cells . Am J Physiol , 277 : L868 – L873 .
  • Vivanco , I and Sawyers , C L . 2002 . The phosphatidylinositol 3-kinase AKT pathway in human cancer . Nat Rev Cancer , 2 : 489 – 501 .
  • Xu , C X , Jin , H , Chung , Y S , Shin , J Y Hwang , S K . 2009 . Low dietary inorganic phosphate affects lung growth of developing mice . J Vet Sci , 10 : 105 – 113 .
  • Iwanaga , K , Yang , Y , Raso , M G , Ma , L Hanna , A E . 2008 . Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer . Cancer Res , 68 : 1119 – 11127 .
  • Jin , H , Xu , C X , Kim , H W , Chung , Y S Shin , J Y . 2008 . Urocanic acid-modified chitosan-mediated PTEN delivery via aerosol suppressed lung tumorigenesis in K-ras(LA1) mice . Cancer Gene Ther , 15 : 275 – 283 .
  • Mamane , Y , Petroulakis , E , LeBacquer , O and Sonenberg , N . 2006 . mTOR, translation initiation and cancer . Oncogene , 25 : 6416 – 6422 .
  • Nave , B T , Ouwens , M , Withers , D J , Alessi , D R and Shepherd , P R . 1999 . Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation . Biochem J , 344 : 427 – 431 .
  • Wislez , M , Loreto Spencer , M , Izzo , J G , Juroske , D M Balhara , K . 2005 . Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ras . Cancer Res , 65 : 3226 – 3235 .
  • Fumarola , C , La Monica , S , Alfieri , R R , Borra , E and Guidotti , G G . 2005 . Cell size reduction induced by inhibition of the mTOR/S6K-signaling pathway protects Jurkat cells from apoptosis . Cell Death Differ , 12 : 1344 – 1357 .
  • Castellvi , J , Garcia , A , Rojo , F , Ruiz-Marcellan , C Gil , A . 2006 . Phosphorylated 4E binding protein 1: a hallmark of cell signaling that correlates with survival in ovarian cancer . Cancer , 107 : 1801 – 1811 .
  • Fingar , D C , Salama , S , Tsou , C , Harlow , E and Blenis , J . 2002 . Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E . Genes Dev , 16 : 1472 – 1487 .
  • Costa , L J . 2007 . Aspects of mTOR biology and the use of mTOR inhibitors in non-Hodgkin's lymphoma . Cancer Treat Rev , 33 : 78 – 84 .
  • Coqueret , O . 2002 . Linking cyclins to transcriptional control . Gene , 299 : 35 – 55 .
  • Lin , L , Wang , Y , Bergman , G , Kelloff , G J Lubet , R A . 2001 . Detection of differentially expressed genes in mouse lung adenocarcinomas . Exp Lung Res , 27 : 217 – 229 .
  • Gautschi , O , Ratschiller , D , Gugger , M , Betticher , D C and Heighway , J . 2007 . Cyclin D1 in non-small cell lung cancer: a key driver of malignant transformation . Lung Cancer , 55 : 1 – 14 .
  • Betticher , D C , Heighway , J , Thatcher , N and Hasleton , P S . 1997 . Abnormal expression of CCND1 and RB1 in resection margin epithelia of lung cancer patients . Br J Cancer , 75 : 1761 – 1768 .

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