294
Views
8
CrossRef citations to date
0
Altmetric
Original Articles

Inhibition of the Androgen Receptor Activity by Coprinus comatus Substances

, &
Pages 1316-1327 | Received 14 Apr 2010, Accepted 03 Oct 2010, Published online: 07 Oct 2011

REFERENCES

  • Thompson , I M , Tangen , C M , Goodman , P J , Lucia , M S and Klein , E A . Chemoprevention of prostate cancer . J Urol , 182 499 – 507 . discussion, 8, 2009
  • Jemal , A , Murray , T , Ward , E , Samuels , A Tiwari , R C . 2005 . Cancer statistics, 2005 . CA Cancer J Clin , 55 : 10 – 30 .
  • Claessens , F , Denayer , S , Van Tilborgh , N , Kerkhofs , S Helsen , C . 2008 . Diverse roles of androgen receptor (AR) domains in AR-mediated signaling . Nucl Recept Signal , 6 : e008
  • Suzuki , H , Ueda , T , Ichikawa , T and Ito , H . 2003 . Androgen receptor involvement in the progression of prostate cancer . Endocr Relat Cancer , 10 : 209 – 216 .
  • Brooke , G N and Bevan , C L . 2009 . The role of androgen receptor mutations in prostate cancer progression . Curr Genomics , 10 : 18 – 25 .
  • Shand , R L and Gelmann , E P . 2006 . Molecular biology of prostate-cancer pathogenesis . Curr Opin Urol , 16 : 123 – 131 .
  • Culig , Z and Bartsch , G . 2006 . Androgen axis in prostate cancer . J Cell Biochem , 99 : 373 – 381 .
  • Feldman , B J and Feldman , D . 2001 . The development of androgen-independent prostate cancer . Nat Rev Cancer , 1 : 34 – 45 .
  • Balk , S P and Knudsen , K E . 2008 . AR, the cell cycle, and prostate cancer . Nucl Recept Signal , 6 : e001
  • Chatterjee , B . 2003 . The role of the androgen receptor in the development of prostatic hyperplasia and prostate cancer . Mol Cell Biochem , 253 : 89 – 101 .
  • Lindequist , U , Niedermeyer , T H and Julich , W D . 2005 . The pharmacological potential of mushrooms . Evid Based Complement Alternat Med , 2 : 285 – 299 .
  • Lull , C , Wichers , H J and Savelkoul , H F . 2005 . Antiinflammatory and immunomodulating properties of fungal metabolites . Mediators Inflamm , 2005 : 63 – 80 .
  • Wasser , S P . 2002 . Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides . Appl Microbiol Biotechnol , 60 : 258 – 274 .
  • Wasser , S P and Weis , A L . 1999 . Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: a modern perspective . Crit Rev Immunol , 19 : 65 – 96 .
  • Lucas , E H , Montesano , R , Pepper , M S , Hafner , M and Sablon , E . 1957 . Tumor inhibitors in Boletus edulis and other holobasidiomycetes . Antibiotics Chemother , 7 : 1 – 4 .
  • Yohida , T O . 1962 . A tumor inhibitor in Lampteromyces japonica . PSEBM , 3 : 676 – 679 .
  • Roland , J F , Chmielewicz , Z F , Weiner , B A , Gross , A M Boening , O P . 1960 . Calvacin: a new antitumor agent . Science , 132 : 1897
  • Ikekawa , T , Uehara , N , Maeda , Y , Nakanishi , M and Fukuoka , F . 1969 . Antitumor activity of aqueous extracts of edible mushrooms . Cancer Res , 29 : 734 – 735 .
  • Yoshioka , Y , Ikekawa , T , Noda , M and Fukuoka , F . 1972 . Studies on antitumor activity of some fractions from basidiomyces. I. An antitumor acidic polysaccharide fraction of P. ostreatus (Fr.) Quel . Chem Pharm Bull (Tokyo) , 20 : 1175 – 1180 .
  • Yang , Q Y and Jong , S C . 1989 . Medicinal mushrooms in China . Mushr Sci , 9 : 631 – 643 .
  • Daba , A S and Ezeronye , O U . 2003 . Anticancer effect of polysaccharides isolated from higher basidiomycetes mushrooms . Afr J Biotechnol , 2 : 672 – 678 .
  • Mayell , M . 2001 . Maitake extracts and their therapeutic potential . Altern Med Rev , 6 : 48 – 60 .
  • Sullivan , R , Smith , J E and Rowan , N J . 2006 . Medicinal mushrooms and cancer therapy: translating a traditional practice into Western medicine . Perspect Biol Med , 49 : 159 – 170 .
  • Ruimi , N , Rwashdeh , H , Wasser , S , Konkimalla , B Efferth , T . Daedalea gibbosa substances inhibit LPS-induced expression of iNOS by suppression of NF-kappaB and MAPK activities in RAW 264.7 macrophage cells . Int J Mol Med , 25 421 – 432 .
  • Yassin , M , Wasser , S P and Mahajna , J . 2008 . Substances from the medicinal mushroom Daedalea gibbosa inhibit kinase activity of native and T315I mutated Bcr-Abl . Int J Oncol , 32 : 1197 – 1204 .
  • Zaidman , B Z , Wasser , S P , Nevo , E and Mahajna , J . 2007 . Androgen receptor-dependent and -independent mechanisms mediate Ganoderma lucidum activities in LNCaP prostate cancer cells . Int J Oncol , 31 : 959 – 967 .
  • Zaidman , B Z , Wasser , S P , Nevo , E and Mahajna , J . 2008 . Coprinus comatus and Ganoderma lucidum interfere with androgen receptor function in LNCaP prostate cancer cells . Mol Biol Rep , 35 : 107 – 117 .
  • Zaidman , B Z , Yassin , M , Mahajna , J and Wasser , S P . 2005 . Medicinal mushroom modulators of molecular targets as cancer therapeutics . Appl Microbiol Biotechnol , 67 : 453 – 468 .
  • Yassin , M , Mahajna , J and Wasser , S P . 2003 . Submerged Cultured mycelium extracts of higher basidiomycetes mushroom selectively inhibit proliferation and induce differeniation of K562 human chronic myelogenous leukemia cells . Int J Med Mushr , 5 : 259 – 274 .
  • Gu , Y H and Leonard , J . 2006 . In vitro effects on proliferation, apoptosis and colony inhibition in ER-dependent and ER-independent human breast cancer cells by selected mushroom species . Oncol Rep , 15 : 417 – 423 .
  • Hartig , P C , Bobseine , K L , Britt , B H , Cardon , M C Lambright , C R . 2002 . Development of two androgen receptor assays using adenoviral transduction of MMTV-luc reporter and/or hAR for endocrine screening . Toxicol Sci , 66 : 82 – 90 .
  • Wilson , V S , Bobseine , K , Lambright , C R and Gray , L E Jr. 2002 . A novel cell line, MDA-kb2, that stably expresses an androgen- and glucocorticoid-responsive reporter for the detection of hormone receptor agonists and antagonists . Toxicol Sci , 66 : 69 – 81 .
  • DeFeo-Jones , D , Barnett , S F , Fu , S , Hancock , P J Haskell , K M . 2005 . Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members . Mol Cancer Ther , 4 : 271 – 279 .
  • Heinlein , C A and Chang , C . 2002 . Androgen receptor (AR) coregulators: an overview . Endocr Rev , 23 : 175 – 200 .
  • Hanahan , D and Weinberg , R A . 2000 . The hallmarks of cancer . Cell , 100 : 57 – 70 .
  • Bindukumar , B , Schwartz , S A , Nair , M P , Aalinkeel , R Kawinski , E . 2005 . Prostate-specific antigen modulates the expression of genes involved in prostate tumor growth . Neoplasia , 7 : 544
  • Small , E J and Roach , M III . 2002 . Prostate-specific antigen in prostate cancer: a case study in the development of a tumor marker to monitor recurrence and assess response . Semin Oncol , 29 : 264 – 273 .
  • Rochette-Egly , C . 2003 . Nuclear receptors: integration of multiple signaling pathways through phosphorylation . Cell Signal , 15 : 355 – 366 .
  • Mellinghoff , I K , Vivanco , I , Kwon , A , Tran , C Wongvipat , J . 2004 . HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability . Cancer Cell , 6 : 517 – 527 .
  • Zhu , Q , Youn , H , Tang , J , Tawfik , O Dennis , K . 2008 . Phosphoinositide 3-OH kinase p85alpha and p110beta are essential for androgen receptor transactivation and tumor progression in prostate cancers . Oncogene , 27 : 4569 – 4579 .
  • Ghosh , P M , Malik , S , Bedolla , R and Kreisberg , J I . 2003 . Akt in prostate cancer: possible role in androgen-independence . Curr Drug Metab , 4 : 487 – 496 .
  • Gao , N , Zhang , Z , Jiang , B H and Shi , X . 2003 . Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer . Biochem Biophys Res Commun , 310 : 1124 – 1132 .
  • Aziz , M H , Nihal , M , Fu , V X , Jarrard , D F and Ahmad , N . 2006 . Resveratrol-caused apoptosis of human prostate carcinoma LNCaP cells is mediated via modulation of phosphatidylinositol 3’-kinase/Akt pathway and Bcl-2 family proteins . Mol Cancer Ther , 5 : 1335 – 1341 .
  • Benitez , D A , Pozo-Guisado , E , Clementi , M , Castellon , E and Fernandez-Salguero , P M . 2007 . Non-genomic action of resveratrol on androgen and oestrogen receptors in prostate cancer: modulation of the phosphoinositide 3-kinase pathway . Br J Cancer , 96 : 1595 – 1604 .
  • Shankar , S and Srivastava , R K . 2007 . Involvement of Bcl-2 family members, phosphatidylinositol 3’-kinase/AKT and mitochondrial p53 in curcumin (diferulolylmethane)-induced apoptosis in prostate cancer . Int J Oncol , 30 : 905 – 918 .
  • Dotan , N , Wasser , S P and Mahajna , J . 2010 . The culinary medical mushroom Coprinus comatus as a natural antiandrogenic modulator . Integr Cancer Ther , 10 : 148 – 159 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.