Sorghum Phenolics Demonstrate Estrogenic Action and Induce Apoptosis in Nonmalignant Colonocytes

REFERENCES

• Larsson , S C , Giovannucci , E , Bergkvist , L and Wolk , A . 2005 . Whole grain consumption and risk of colorectal cancer: a population-based cohort of 60,000 women . Br J Cancer , 92 : 1803 – 1807 .
   PubMed Web of Science ®Google Scholar
• Awika , J M , Yang , L , Browning , J D and Faraj , A . 2009 . Comparative antioxidant, antiproliferative and phase II enzyme inducing potential of sorghum (sorghum bicolor) varieties . LWT–Food Sci Technol , 42 : 1041 – 1046 .
   Web of Science ®Google Scholar
• Yang , L , Browning , J D and Awika , J M . 2009 . Sorghum 3-deoxyanthocyanins possess strong phase II enzyme inducer activity and cancer cell growth inhibition properties . J Agric Food Chem , 57 : 1797 – 1804 .
   PubMed Web of Science ®Google Scholar
• Chen , F , Cole , P , Mi , Z B and Xing , L Y . 1993 . Corn and wheat-flour consumption and mortality from esophageal cancer in Shanxi, China . Intl J Cancer , 53 : 902 – 906 .
   PubMed Web of Science ®Google Scholar
• Isaacson , C . 2005 . The change of the staple diet of black South Africans from sorghum to maize (corn) is the cause of the epidemic of squamous carcinoma of the oesophagus . Med Hypotheses , 64 : 658 – 660 .
   PubMed Web of Science ®Google Scholar
• Awika , J M and Rooney , L W . 2004 . Sorghum phytochemicals and their potential impact on human health . Phytochem , 65 : 1199 – 1221 .
   PubMed Web of Science ®Google Scholar
• Dykes , L , Seitz , L M , Rooney , W L and Rooney , L W . 2009 . Flavonoid composition of red sorghum genotypes . Food Chem , 116 : 313 – 317 .
   Web of Science ®Google Scholar
• Hall , J M , Couse , J F and Korach , K S . 2001 . The multifaceted mechanisms of estradiol and estrogen receptor signaling . J Biol Chem , 276 : 36869 – 36872 .
   PubMed Web of Science ®Google Scholar
• Segars , J H and Driggers , P H . 2002 . Estrogen action and cytoplasmic signaling cascades. Part I: membrane-associated signaling complexes . Trends Endocrinol Metab , 13 : 349 – 354 .
   PubMed Web of Science ®Google Scholar
• Rossouw , J E , Anderson , G L , Prentice , R L , LaCroix , A Z Kooperberg , C . 2002 . Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial . JAMA , 288 : 321 – 333 .
   PubMed Web of Science ®Google Scholar
• Slattery , M L , Anderson , K , Samowitz , W , Edwards , S L Curtin , K . 1999 . Hormone replacement therapy and improved survival among postmenopausal women diagnosed with colon cancer (USA) . Cancer Causes Control , 10 : 467 – 473 .
   PubMed Web of Science ®Google Scholar
• Weige , C C , Allred , K F and Allred , C D . 2009 . Estradiol alters cell growth in nonmalignant colonocytes and reduces the formation of preneoplastic lesions in the colon . Cancer Res , 69 : 9118 – 9124 .
   PubMed Web of Science ®Google Scholar
• Jemal , A , Siegel , R , Xu , J and War , E . 2010 . Cancer statistics . CA: Cancer J Clin , 60 : 277 – 300 .
   PubMed Web of Science ®Google Scholar
• Foley , E F , Jazaeri , A A , Shupnik , M A , Jazaeri , O and Rice , L W . 2000 . Selective loss of estrogen receptor b in malignant human colon . Cancer Res , 60 : 245 – 248 .
   PubMed Web of Science ®Google Scholar
• Yu , Z , Li , W and Liu , F . 2004 . Inhibition of proliferation and induction of apoptosis by genistein in colon cancer HT-29 cells . Cancer Lett , 215 : 159 – 166 .
   PubMed Web of Science ®Google Scholar
• Raju , J , Bielecki , A , Caldwell , D , Lok , E Taylor , M . 2009 . Soy isoflavones modulate azoxymethane-induced rat colon carcinogenesis exposed pre- and postnatally and inhibit growth of DLD-1 human colon adenocarcinoma cells by increasing the expression of estrogen receptor-b . J Nutr , 139 : 474 – 481 .
   PubMed Web of Science ®Google Scholar
• Bielecki , A , Roberts , J , Mehta , R and Raju , J A . 2011 . Estrogen receptor-b mediates the inhibition of DLD-1 human colon adenocarcinoma cells by soy isoflavones . Nutr Cancer , 63 : 139 – 150 .
   PubMed Web of Science ®Google Scholar
• Mak , P , Leung , Y , Tang , W , Harwood , C and Ho , S . 2006 . Apigenin suppresses cancer cell growth through ERb . Neoplasia , 8 : 896 – 904 .
   PubMed Web of Science ®Google Scholar
• Ruh , M F , Zacharewski , T , Connor , K , Howell , J Chen , I . 1995 . Naringenin: a weakly estrogenic bioflavonoid that exhibits antiestrogenic activity . Biochem Pharmacol , 50 : 1485 – 1493 .
   PubMed Web of Science ®Google Scholar
• Soule , H D , Vazguez , J , Long , A , Albert , S and Brennan , M . 1973 . A human cell line from a pleural effusion derived from a breast carcinoma . J Natl Cancer Inst , 51 : 1409 – 1416 .
   PubMed Web of Science ®Google Scholar
• Whitehead , R H , VanEeden , P E , Noble , M D , Ataliotis , P and Jat , P S . 1993 . Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice . Proc Natl Acad Sci USA , 90 : 587 – 591 .
   PubMed Web of Science ®Google Scholar
• Ju , Y H , Doerge , D R , Allred , K F , Allred , C D and Helferich , W G . 2002 . Dietary genistein negates the inhibitory effect of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic mice . Cancer Res , 62 : 2474 – 2477 .
   PubMed Web of Science ®Google Scholar
• Allred , K F , Yackley , K M , Vanamala , J and Allred , C D . 2009 . Trigonelline is a novel phytoestrogen in coffee beans . J Nutr , 139 : 1833 – 1838 .
   PubMed Web of Science ®Google Scholar
• Billimek , A R . 2011 . “ Estradiol and genistein alter cellular physiology of non-malignant colonocytes ” . Master of Science Thesis, Texas A&M University .
   Google Scholar
• Stettner , M , Kaulfuss , S , Burfeind , P , Schweyer , S Strauss , A . 2007 . The relevance of estrogen receptor-beta expression to the antiproliferative effects observed with histone deacetylase inhibitors and phytoestrogens in prostate cancer treatment . Mol Cancer Ther , 5 : 2626 – 2633 .
   Web of Science ®Google Scholar
• Chang , W C , Chapkin , R S and Lupton , J R . 1998 . Fish oil blocks azoxymethane-induced rat colon tumorigenesis by increasing cell differentiation and apoptosis rather than decreasing cell proliferation . J Nutr , 128 : 491 – 497 .
   PubMed Web of Science ®Google Scholar
• Svensson , L , Sekwati-Monang , B , Lutz , D L , Schieber , A and Ganzle , M G . 2010 . Phenolic acids and flavonoids in nonfermented and fermented red sorghum (Sorghum bicolor (L.) Moench) . J Agric Food Chem , 58 : 9214 – 9220 .
   PubMed Web of Science ®Google Scholar
• Ma , C , Xiao , S Y , Li , Z G , Wang , W and Du , L J . 2007 . Characterization of active phenolic components in the ethanolic extract of Ananas comosus L. leaves using high-performance liquid chromatography with diode array detection and tandem mass spectrometry . J Chromatogr A , 1165 : 39 – 44 .
   Web of Science ®Google Scholar
• Takaya , Y , Kondo , Y , Rurukawa , T and Niwa , M . 2003 . Antioxidant constituents of radish sprout (Kaiware-daikon), Raphanus sativus L . J Agric Food Chem , 51 : 8061 – 8066 .
   PubMed Web of Science ®Google Scholar
• Awika , J M , Waniska , R D and Rooney , L W . 2004 . Properties of 3-deoxyanthocyanins from sorghum . J Agric Food Chem , 52 : 4388 – 4394 .
   PubMed Web of Science ®Google Scholar
• Shih , C H , Siu , S O , Ng , R , Wong , E Chiu , L CM . 2007 . Quantitative analysis of anticancer 3-deoxyanthocyanidins in infected sorghum seedlings . J Agric Food Chem , 55 : 254 – 259 .
   PubMed Web of Science ®Google Scholar