497
Views
106
CrossRef citations to date
0
Altmetric
Original Articles

Potential Anticancer Activity of Myricetin in Human T24 Bladder Cancer Cells Both In Vitro and In Vivo

, , , , &
Pages 599-606 | Received 15 Sep 2011, Accepted 27 Jan 2012, Published online: 06 Apr 2012

REFERENCES

  • Whelan , P . 2008 . Survival from bladder cancer in England and Wales up to 2001 . Br J Cancer , 99 ( Suppl 1 ) : S90 – S92 .
  • Jemal , A , Siegel , R and Ward , E . 2009 . Cancer statistics, 2009 . CA Cancer J Clin , 59 : 225 – 249 .
  • Mitra , A P and Cote , R J . 2010 . Molecular screening for bladder cancer: progress and potential . Nat Rev Uro , 7 : 11 – 20 .
  • Kakehi , Y , Hirao , Y and Kim , W J . 2010 . Bladder Cancer Working Group report . Jpn J Clin Oncol , 40 ( Suppl 1 ) : i57 – i64 .
  • Voskresensky , O N and Levitsky , A P . 2002 . QSAR aspects of flavonoids as a plentiful source of new drugs . Curr Med Chem , 14 : 1367 – 1383 .
  • Zhang , K , Ma , Z and Wang , J . 2011 . Myricetin attenuated MPP(+)-induced cytotoxicity by antioxidation and inhibition of MKK4 and JNK activation in MES23.5 cells . Neuropharmacology , 61 : 329 – 335 .
  • Wang , S J , Tong , Y and Lu , S . 2010 . Anti-inflammatory activity of myricetin isolated from Myrica rubra Sieb. et Zucc. leaves . Planta Med , 76 : 1492 – 1496 .
  • Zhang , Q , Zhao , X H and Wang , Z J . 2008 . Flavones and flavonols exert cytotoxic effects on a human oesophageal adenoearcinonla cell line (0E33) by causing G2/M arrest and inducing apoptosis . Food Chem Toxicol , 46 : 2042 – 2053 .
  • Lu , J , Papp , L V and Fang , J . 2006 . Inhibition of mammalian thioredoxin reductase by some flavonoids: implications for myricetin and quercetin anticancer activity . Cancer Res , 66 : 4410 – 4418 .
  • Chen , D , Daniel , K G and Chen , M S . 2005 . Dietary flavonoids as proteasome inhibitors and apoptosis inducers in human leukemia cells . Biochem Pharmacol , 69 : 1421 – 1432 .
  • De Leo , M , Braca , A and Sanogo , R . 2006 . Antiproliferative activity of Pteleopsis suberosa leaf extract and its flavonoid components in human prostate carcinoma cells . Planta Med , 72 : 604 – 610 .
  • Jung , S K , Lee , K W and Byun , S . 2008 . Myricetin suppresses UVB-induced skin cancer by targeting Fyn . Cancer Res , 68 : 6021 – 6029 .
  • Ko , C H , Shen , S C and Lee , T J . 2005 . Myricetin inhibits matrix metalloproteinase 2 protein expression and enzyme activity in colorectal carcinoma cells . Mol Cancer Ther , 4 : 281 – 290 .
  • Singh , R P , Tyagi , A , Sharma , G , Mohan , S and Agarwal , R . 2008 . Oral silibinin inhibits in vivo human bladder tumor xenograft growth involving down-regulation of survivin . Clin Cancer Res , 14 : 300 – 308 .
  • Jung , S K , Lee , K W and Byun , S . 2010 . Myricetin inhibits UVB-induced angiogenesis by regulating PI-3 kinase in vivo . Carcinogenesis , 31 : 911 – 917 .
  • Zhang , X H , Zou , Z Q and Xu , C W . 2011 . Myricetin induces G2/M phase arrest in HepG2 cells by inhibiting the activity of the cyclin B/Cdc2 complex . Mol Med Report , 4 : 273 – 277 .
  • Araújo , J R , Gonçalves , P and Martel , F . 2011 . Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines . Nutr Res , 31 : 77 – 87 .
  • Luo , J , Manning , B D and Cantley , L C . 2003 . Targeting the PI3K-Akt pathwayin human cancer: rationale and promise . Cancer Cell , 4 : 257 – 62 .
  • Fresno Vara , J A , Casado , E , de Castro , J , Cejas , P and Belda-Iniesta , C . 2004 . PI3K/Akt signalling pathway and cancer . Cancer Treat Rev , 30 : 193 – 204 .
  • Cuadrado , A and Nebreda , A R . 2010 . Mechanisms and functions of p38 MAPK signalling . Biochem J , 429 : 403 – 417 .
  • Shahjee , H M , Koch , K R and Guo , L . 2010 . Antiproliferative factor decreases Akt phosphorylation and alters gene expression via CKAP4 in T24 bladder carcinoma cells . J Exp Clin Cancer Res , 29 : 160
  • Astuti , P , Pike , T and Widberg , C . 2009 . MAPK pathway activation delays G2/M progression by destabilizing Cdc25B . J Biol Chem , 284 : 33781 – 33788 .
  • Kessenbrock , K , Plaks , V and Werb , Z . 2010 . Matrix metalloproteinases: regulators of the tumor microenvironment . Cell , 141 : 52 – 67 .
  • Liu , F T , Agrawal , S G and Movasaghi , Z . 2008 . Dietary flavonoids inhibit the anticancer effects of the proteasome inhibitor bortezomib . Blood , 112 : 3835 – 3846 .
  • Gonçalves , P , Araújo , J R and Pinho , M J . 2011 . In vitro studies on the inhibition of colon cancer by butyrate and polyphenolic compounds . Nutr Cancer , 63 : 282 – 294 .
  • Paganga , G and Rice-Evans , C A . 1997 . The identification of flavonoids as glycosides in human plasm . FEBS Lett , 401 : 78 – 82 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.