Fucoidan Inhibited 4T1 Mouse Breast Cancer Cell Growth In Vivo and In Vitro Via Downregulation of Wnt/β-Catenin Signaling

REFERENCES

• Bilan , M I , Grachev , A A , Shashkov , A S , Nifantiev , N E and Usov , A I . 2006 . Structure of a fucoidan from the brown seaweed Fucus serratus L . Carbohydrate Research , 341 : 238 – 245 .
   PubMed Web of Science ®Google Scholar
• Li , B , Lu , F , Wei , X and Zhao , R . 2008 . Fucoidan: structure and bioactivity . Molecules , 13 : 1671 – 1695 .
   PubMed Web of Science ®Google Scholar
• Maruyama , H , Tamauchi , H , Hashimoto , M and Nakano , T . 2003 . Antitumor activity and immune response of Mekabu fucoidan extracted from Sporophyll of Undaria pinnatifida . In Vivo , 17 : 245 – 249 .
   PubMed Web of Science ®Google Scholar
• Hyun , J H , Kim , S C , Kang , J I , Kim , M K Boo , H J . 2009 . Apoptosis inducing activity of fucoidan in HCT-15 colon carcinoma cells . Biol Pharm Bull , 32 : 1760 – 1764 .
   PubMed Web of Science ®Google Scholar
• Philchenkov , A , Zavelevich , M , Imbs , T , Zvyagintseva , T and Zaporozhets , T . 2007 . Sensitization of human malignant lymphoid cells to etoposide by fucoidan, a brown seaweed polysaccharide . Exp Oncol , 29 : 181 – 185 .
   PubMedGoogle Scholar
• Ermakova , S , Sokolova , R , Kim , S M , Um , B H Isakov , V . 2011 . Fucoidans from brown seaweeds Sargassum hornery, Eclonia cava, Costaria costata: structural characteristics and anticancer activity . Appl Biochem Biotechnol , 164 : 841 – 850 .
   PubMed Web of Science ®Google Scholar
• Haneji , K , Matsuda , T , Tomita , M , Kawakami , H Ohshiro , K . 2005 . Fucoidan extracted from Cladosiphon okamuranus Tokida induces apoptosis of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells . Nutr Cancer , 52 : 189 – 201 .
   PubMed Web of Science ®Google Scholar
• Yamasaki-Miyamoto , Y , Yamasaki , M , Tachibana , H and Yamada , K . 2009 . Fucoidan induces apoptosis through activation of caspase-8 on human breast cancer MCF-7 cells . J Agric Food Chem , 57 : 8677 – 8682 .
   PubMed Web of Science ®Google Scholar
• Fukahori , S , Yano , H , Akiba , J , Ogasawara , S Momosaki , S . 2008 . Fucoidan, a major component of brown seaweed, prohibits the growth of human cancer cell lines in vitro . Mol Med Report , 1 : 537 – 542 .
   PubMed Web of Science ®Google Scholar
• Polakis , P . 1999 . The oncogenic activation of beta-catenin . Curr Opin Genet Dev , 9 : 15 – 21 .
   PubMed Web of Science ®Google Scholar
• Cowin , P , Rowlands , T M and Hatsell , S J . 2005 . Cadherins and catenins in breast cancer . Curr Opin Cell Biol , 17 : 499 – 508 .
   PubMed Web of Science ®Google Scholar
• Behrens , J . 2000 . Control of beta-catenin signaling in tumor development . Ann N Y Acad Sci , 910 : 21 – 33 .
   PubMed Web of Science ®Google Scholar
• Liu , C , Li , Y , Semenov , M , Han , C Baeg , G H . 2002 . Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism . Cell , 108 : 837 – 847 .
   PubMed Web of Science ®Google Scholar
• Molenaar , M , van de Wetering , M , Oosterwegel , M , Peterson-Maduro , J Godsave , S . 1996 . XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos . Cell , 86 : 391 – 399 .
   PubMed Web of Science ®Google Scholar
• Kang , D W , Min , G , Park do , Y , Hong , K W and Min do , S . 2010 . Rebamipide-induced downregulation of phospholipase D inhibits inflammation and proliferation in gastric cancer cells . Exp Mol Med , 42 : 555 – 564 .
   PubMed Web of Science ®Google Scholar
• Zhang , X , Deng , H X , Zhao , X , Su , D Chen , X C . 2009 . RNA interference-mediated silencing of the phosphatidylinositol 3-kinase catalytic subunit attenuates growth of human ovarian cancer cells in vitroand in vivo . Oncology , 77 ( 1 ) : 22 – 32 .
   PubMed Web of Science ®Google Scholar
• Gehrke , I , Gandhirajan , R K and Kreuzer , K A . 2009 . Targeting the WNT/beta-catenin/TCF/LEF1 axis in solid and haematological cancers: Multiplicity of therapeutic options . Eur J Cancer , 45 : 2759 – 2767 .
   PubMed Web of Science ®Google Scholar
• Ale , M T , Maruyama , H , Tamauchi , H , Mikkelsen , J D and Meyer , A S . 2011 . Fucoidan from Sargassum sp. and Fucus vesiculosus reduces cell viability of lung carcinoma and melanoma cells in vitro and activates natural killer cells in mice in vivo . Int J Biol Macromol , 49 : 331 – 336 .
   PubMed Web of Science ®Google Scholar
• Kim , E J , Park , S Y , Lee , J Y and Park , J H . 2010 . Fucoidan present in brown algae induces apoptosis of human colon cancer cells . BMC Gastroenterol , 10 : 96
   PubMed Web of Science ®Google Scholar
• Park , H S , Kim , G Y , Nam , T J , Deuk Kim , N and Hyun Choi , Y . 2011 . Antiproliferative activity of fucoidan was associated with the induction of apoptosis and autophagy in AGS human gastric cancer cells . J Food Sci , 76 : T77 – T83 .
   PubMed Web of Science ®Google Scholar
• Nagamine , T , Hayakawa , K , Kusakabe , T , Takada , H Nakazato , K . 2009 . Inhibitory effect of fucoidan on Huh7 hepatoma cells through downregulation of CXCL12 . Nutr Cancer , 61 : 340 – 347 .
   PubMed Web of Science ®Google Scholar
• Sekiya , M , Funahashi , H , Tsukamura , K , Imai , T Hayakawa , A . 2005 . Intracellular signaling in the induction of apoptosis in a human breast cancer cell line by water extract of Mekabu . Int J Clin Oncol , 10 : 122 – 126 .
   PubMedGoogle Scholar
• Coombe , D R , Parish , C R , Ramshaw , I A and Snowden , J M . 1987 . Analysis of the inhibition of tumour metastasis by sulphated polysaccharides . Int J Cancer , 39 : 82 – 88 .
   PubMed Web of Science ®Google Scholar
• Alekseyenko , T V , Zhanayeva , S Y , Venediktova , A A , Zvyagintseva , T N Kuznetsova , T A . 2007 . Antitumor and antimetastatic activity of fucoidan, a sulfated polysaccharide isolated from the Okhotsk Sea Fucus evanescens brown alga . Bull Exp Biol Med , 143 : 730 – 732 .
   PubMed Web of Science ®Google Scholar
• Riou , D , Colliec-Jouault , S , Pinczon du Sel , D , Bosch , S Siavoshian , S . 1996 . Antitumor and antiproliferative effects of a fucan extracted from ascophyllum nodosum against a non-small-cell bronchopulmonary carcinoma line . Anticancer Res , 16 ( 3A ) : 1213 – 1218 .
   PubMed Web of Science ®Google Scholar
• Boo , H J , Hyun , J H , Kim , S C , Kang , J I Kim , M K . 2011, Mar 31 . Fucoidan from Undaria pinnatifida Induces Apoptosis in A549 Human Lung Carcinoma Cells . Phytother Res , 25 : 1082 – 1086 . doi: 10.1002/ptr.3489
   PubMed Web of Science ®Google Scholar
• Aisa , Y , Miyakawa , Y , Nakazato , T , Shibata , H Saito , K . 2005 . Fucoidan induces apoptosis of human HS-sultan cells accompanied by activation of caspase-3 and down-regulation of ERK pathways . Am J Hematol , 78 ( 1 ) : 7 – 14 .
   PubMed Web of Science ®Google Scholar
• Ye , J , Li , Y , Teruya , K , Katakura , Y Ichikawa , A . 2005 . Enzyme-digested fucoidan extracts derived from seaweed mozuku of cladosiphon novae-caledoniae kylin inhibit invasion and angiogenesis of tumor cells . Cytotechnology , 47 : 117 – 126 .
   PubMed Web of Science ®Google Scholar
• Polakis , P . 2000 . Wnt signaling and ancer . Genes Dev , 14 : 1837 – 1851 .
   PubMed Web of Science ®Google Scholar
• Zhurinsky , J , Shtutman , M and Ben-Ze’ev , A . 2000 . Plakoglobin and β-catenin: protein interactions, regulation and biological roles . J Cell Sci , 113 ( Pt. 18 ) : 3127 – 3139 .
   PubMed Web of Science ®Google Scholar
• Mucci , L A , Wedren , S , Tamimi , R M , Trichopoulos , D and Adami , H O . 2001 . The role of geneenvironment interaction in the aetiology of human cancer: examples from cancers of the large bowel, lung and breast . J Intern Med , 249 : 477 – 493 .
   PubMed Web of Science ®Google Scholar
• Sherr , C J . 1995 . Mammalian G1 cyclins and cell cycle progression . Proc Assoc Am Physicians , 107 : 181 – 186 .
   PubMedGoogle Scholar
• Bose , S , Chandran , S , Mirocha , J M and Bose , N . 2006 . The Akt pathway in human breast cancer: a tissue-array-based analysis . Mod Pathol , 19 : 238 – 245 .
   PubMed Web of Science ®Google Scholar
• Vita , M and Henriksson , M . 2006 . The Myc oncoprotein as a therapeutic target for human cancer . Semin Cancer Biol , 16 ( 4 ) : 318 – 330 .
   PubMed Web of Science ®Google Scholar
• Li , F , Ambrosini , G , Chu , E Y , Plescia , J Tognin , S . 1998 . Control of apoptosis and mitotic spindle checkpoint by survivin . Nature , 396 ( 6711 ) : 580 – 584 .
   PubMed Web of Science ®Google Scholar
• Johnson , M E and Howerth , E W . 2004 . Survivin: a bifunctional inhibitor of apoptosis protein . Vet Pathol , 41 : 599 – 607 .
   PubMed Web of Science ®Google Scholar