REFERENCES
- Goeckenjan , G . 2010 . Lung cancer - historical development, current status, future prospects . Pneumologie , 64 : 555 – 559 .
- Siegel , R , Naishasham , D and Jemal , A . 2012 . Cancer statistics , Vol. 62 , 10 – 29 . CA Cancer J Clin .
- Amin , A R , Wang , D , Zhang , H , Peng , S Shin , H J . 2010 . Enhanced anti-tumor activity by the combination of natural compounds, (-)-epigallocatechin-3-gallate and luteolin: potential role of p53 . J Biol Chem , 285 : 34557 – 34565 .
- Naithani , R , Huma , L C , Moriarty , R M , McCormick , D L and Mehta , R G . 2008 . Comprehensive review of cancer chemopreventive agents evaluated in experimental carcinogenesis models and clinical trials . Curr Med Chem , 15 : 1044 – 1071 .
- Tan , H L , Thomas-Ahner , J M , Grainger , E M , Wan , L Francis , D M . 2010 . Tomato-based food products for prostate cancer prevention: what have we learned? . Cancer Metastasis Rev , 29 : 553 – 568 .
- Kaur , M , Agarwal , C and Agarwal , R . 2009 . Anticancer and cancer chemopreventive potential of grape seed extract and other grape-based products . J Nutr , 139 : 1806S – 1812S .
- Raina , K , Singh , R P , Agarwal , R and Agarwal , C . 2007 . Oral grape seed extract inhibits prostate tumor growth and progression in TRAMP mice . Cancer Res , 67 : 5976 – 5982 .
- Velmurugan , B , Singh , R P , Kaul , N , Agarwal , R and Agarwal , C . 2010 . Dietary feeding of grape seed extract prevents intestinal tumorigenesis in APCmin/+ mice . Neoplasia , 12 : 95 – 102 .
- Song , X , Siriwardhana , N , Rathore , K , Lin , D and Wang , H C . 2010 . Grape seed proanthocyanidin suppression of breast cell carcinogenesis induced by chronic exposure to combined 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene . Mol Carcinog , 49 : 450 – 463 .
- Wondrak , G T . 2009 . Redox-directed cancer therapeutics: molecular mechanisms and opportunities . Antioxid Redox Signal , 11 : 3013 – 3069 .
- Sung , B , Ravindran , J , Prasad , S , Pandey , M K and Aggarwal , B B . 2010 . Gossypol induces death receptor-5 through activation of ROS-ERK-chop pathway and sensitizes colon cancer cells to trail . J Biol Chem , 285 : 35418 – 35427 .
- Danial , N N . 2007 . BCL-2 family proteins: critical checkpoints of apoptotic cell death . Clin Cancer Res , 13 : 7254 – 7263 .
- LaCasse , E C , Mahoney , D J , Cheung , H H , Plenchette , S Baird , S . 2008 . IAP-targeted therapies for cancer . Oncogene , 27 : 6252 – 6275 .
- Kralova , J , Sheely , J I , Liss , A S and Bose , H R Jr. 2010 . ERK and JNK activation is essential for oncogenic transformation by v-Rel . Oncogene , 29 : 6267 – 6279 .
- Gu , M , Raina , K , Agarwal , C and Agarwal , R . 2010 . Inositol hexaphosphate downregulates both constitutive and ligand-induced mitogenic and cell survival signaling, and causes caspase-mediated apoptotic death of human prostate carcinoma PC-3 cells . Mol Carcinog , 49 : 1 – 12 .
- Hu , H , Jiang , C , Li , G and Lu , J . 2005 . PKB/AKT and ERK regulation of caspase-mediated apoptosis by methylseleninic acid in LNCaP prostate cancer cells . Carcinogenesis , 26 : 1374 – 1381 .
- Kaur , M , Agarwal , R and Agarwal , C . 2006 . Grape seed extract induces anoikis and caspase-mediated apoptosis in human prostate carcinoma LNCaP cells: possible role of ataxia telangiectasia mutated-p53 activation . Mol Cancer Ther , 5 : 1265 – 1274 .
- Veluri , R , Singh , R P , Liu , Z , Thompson , J A Agarwal , R . 2006 . Fractionation of grape seed extract and identification of gallic acid as one of the major active constituents causing growth inhibition and apoptotic death of DU145 human prostate carcinoma cells . Carcinogenesis , 27 : 1445 – 1453 .
- Chou , S C , Kaur , M , Thompson , J A , Agarwal , R and Agarwal , C . 2010 . Influence of gallate esterification on the activity of procyanidin B2 in androgen-dependent human prostate carcinoma LNCaP cells . Pharm Res , 27 : 619 – 627 .
- Tyagi , A , Gu , M , Takahata , T , Frederick , B Agarwal , C . 2011 . Resveratrol selectively induces DNA Damage, independent of Smad4 expression, in its efficacy against human head and neck squamous cell carcinoma . Clin Cancer Res , 17 : 5402 – 5411 .
- Ling , Y H , Aracil , M , Jimeno , J , Perez-Soler , R and Zou , Y . 2009 . Molecular pharmacodynamics of PM02734 (elisidepsin) as single agent and in combination with erlotinib; synergistic activity in human non-small cell lung cancer cell lines and xenograft models . Eur J Cancer , 45 : 1855 – 1864 .
- Mateen , S , Tyagi , A , Agarwal , C , Singh , R P and Agarwal , R . 2010 . Silibinin inhibits human nonsmall cell lung cancer cell growth through cell-cycle arrest by modulating expression and function of key cell-cycle regulators . Mol Carcinog , 49 : 247 – 258 .
- Li , G X , Hu , H , Jiang , C , Schuster , T and Lu , J . 2007 . Differential involvement of reactive oxygen species in apoptosis induced by two classes of selenium compounds in human prostate cancer cells . Int J Cancer , 120 : 2034 – 2043 .
- Riely , G J , Marks , J and Pao , W . 2009 . KRAS mutations in non-small cell lung cancer . Proc Am Thorac Soc , 6 : 201 – 205 .
- Tyagi , A , Agarwal , R and Agarwal , C . 2003 . Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in antiproliferation and apoptosis . Oncogene , 22 : 1302 – 1316 .
- Dalle-Donne , I , Rossi , R , Colombo , R , Giustarini , D and Milzani , A . 2006 . Biomarkers of oxidative damage in human disease . Clin Chem , 52 : 601 – 623 .
- Packer , L and Cadenas , E . 2007 . Oxidants and antioxidants revisited. New concepts of oxidative stress . Free Radic Res , 41 : 951 – 952 .
- Gibson , S B . 2010 . A matter of balance between life and death: Targeting reactive oxygen species (ROS)-induced autophagy for cancer therapy . Autophagy , 6 : 835 – 837 .
- Essick , E E and Sam , F . 2010 . Oxidative stress and autophagy in cardiac disease, neurological disorders, aging and cancer . Oxid Med Cell Longev , 3 : 168 – 177 .
- Xiao , D , Powolny , A A , Moura , M B , Kelley , E E Bommareddy , A . 2010 . Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells . J Biol Chem , 285 : 26558 – 26569 .
- Mackenzie , G G , Sun , Y , Huang , L , Xie , G Ouyang , N . 2010 . Phospho-sulindac (OXT-328), a novel sulindac derivative, is safe and effective in colon cancer prevention in mice . Gastroenterology , 139 : 1320 – 1322 .
- Tarrega , C , Nunes-Xavier , C , Cejudo-Marin , R , Martin-Perez , J and Pulido , R . 2010 . Studying the regulation of MAP Kinase by MAP Kinase phosphatases in vitro and in cell systems . Methods Mol Biol , 661 : 305 – 321 .
- Woo , J H , Kim , Y H , Choi , Y J , Kim , D G Lee , K S . 2003 . Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt . Carcinogenesis , 24 : 1199 – 1208 .
- Okamoto , K , Okamoto , I , Okamoto , W , Tanaka , K Takezawa , K . 2010 . Role of survivin in EGFR inhibitor-induced apoptosis in non-small cell lung cancers positive for EGFR mutations . Cancer Res , 70 : 10402 – 10410 .
- Kumar , P , Coltas , I K , Kumar , B , Chepeha , D B Bradford , C R . 2007 . Bcl-2 protects endothelial cells against gamma-radiation via a Raf-MEK-ERK-survivin signaling pathway that is independent of cytochrome c release . Cancer Res , 67 : 1193 – 1202 .