354
Views
32
CrossRef citations to date
0
Altmetric
Original Articles

Immunomodulatory Activities of Ganoderma sinense Polysaccharides in Human Immune Cells

, , , , , , , , , & show all
Pages 765-774 | Received 17 May 2012, Accepted 11 Feb 2013, Published online: 16 Jul 2013

REFERENCES

  • Chang , H M and But , R P . 1986 . “ Pharmacology and applications of Chinese Materia Medica ” . In Pharmacology and Applications of Chinese Materia Medica , Edited by: Chang , H M and But , R P . 593 – 602 . Singapore : World Scientific .
  • Chinese Pharmacopoeia Commission . 2010 . Chinese Pharmacopoeia , 117 – 118 . Shanghai : Shang Wu Yin Shu Guan .
  • Tan , A C , Konczak , I , Ramzan , I and Sze , D M . 2011 . Native Australian fruit polyphenols inhibit cell viability and induce apoptosis in human cancer cell lines . Nutr Cancer , 63 : 444 – 455 .
  • Tan , A C , Konczak , I , Ramzan , I , Zabaras , D and Sze , D M . 2011 . Potential antioxidant, antiinflammatory, and proapoptotic anticancer activities of Kakadu plum and Illawarra plum polyphenolic fractions . Nutr Cancer , 63 : 1074 – 1084 .
  • Tan , A C , Konczak , I , Sze , D M and Ramzan , I . 2011 . Molecular pathways for cancer chemoprevention by dietary phytochemicals . Nutr Cancer , 63 : 495 – 505 .
  • Yue , G GL , Fung , K P , Tse , G M , Leung , P C and Lau , C BS . 2006 . Comparative studies of various Ganoderma species and their different parts with regard to their antitumor and immunomodulating activities in vitro . J Altern Complement Med , 12 : 777 – 789 .
  • Liu , Y W , Gao , J L , Guan , J , Qian , Z M Feng , K . 2009 . Evaluation of antiproliferative activities and action mechanisms of extracts from two species of Ganoderma on tumor cell lines . J Agric Food Chem , 57 : 3087 – 3093 .
  • Cheng , C H , Leung , A Y and Chen , C F . 2010 . The effects of two different Ganoderma species (Lingzhi) on gene expression in human monocytic THP-1 cells . Nutr Cancer , 62 : 648 – 658 .
  • Zhang , J P , Zheng , L , Wang , J H , Magnusson , K E and Liu , X . 2009 . Lipid extract from completely sporoderm-broken germinating Ganoderma sinensis spores elicits potent antitumor immune responses in human macrophages . Phytothr Res , 23 : 844 – 850 .
  • Li , Q , Wang , X , Chen , Y , Lin , J and Zhou , X . 2010 . Cytokines expression induced by Ganoderma sinensis fungal immunomodulatory proteins (FIP-gsi) in mouse spleen cells . Appl Biochem Biotechnol , 162 : 1403 – 1413 .
  • Miyazaki , T and Nishijima , M . 1981 . Studies on fungal polysaccharides. XXVII. Structural examination of a water-soluble, antitumor polysaccharide of Ganoderma lucidum . Chem Pharm Bull (Tokyo) , 29 : 3611 – 3616 .
  • Hsu , M J , Lee , S S , Lee , S T and Lin , W W . 2003 . Signaling mechanisms of enhanced neutrophil phagocytosis and chemotaxis by the polysaccharide purified from Ganoderma lucidum . Br J Pharmacol , 139 : 289 – 298 .
  • Lin , Y L , Liang , Y C , Lee , S S and Chiang , B L . 2005 . Polysaccharide purified from Ganoderma lucidum induced activation and maturation of human monocyte-derived dendritic cells by the NF-kappaB and p38 mitogen-activated protein kinase pathways . J Leukoc Biol , 78 : 533 – 543 .
  • Hua , K F , Hsu , H Y , Chao , L K , Chen , S T Yang , W B . 2007 . Ganoderma lucidum polysaccharides enhance CD14 endocytosis of LPS and promote TLR4 signal transduction of cytokine expression . J. Cell Physiol , 212 : 537 – 550 .
  • Zhao , L Y , Dong , Y H , Chen , G T and Hu , Q H . 2010 . Extraction, purification, characterization and antitumor activity of polysaccharides from Ganoderma lucidum . Carbohydr Polym , 80 : 783 – 789 .
  • Qiao , Y , Zhang , X M and Qiu , M H . 2007 . Two novel lanostane triterpenoids from Ganoderma sinense . Molecules , 12 : 2038 – 2046 .
  • Gao , J L , Leung , K S , Wang , Y T , Lai , C M Li , S P . 2007 . Qualitative and quantitative analyses of nucleosides and nucleobases in Ganoderma spp. by HPLC-DAD-MS . J Pharm Biomed Anal , 44 : 807 – 811 .
  • Sato , N , Ma , C M , Komatsu , K and Hattori , M . 2009 . Triterpene-farnesyl hydroquinone conjugates from Ganoderma sinense . J Nat Prod , 72 : 958 – 961 .
  • Liu , C , Zhao , F and Chen , R Y . 2010 . A novel alkaloid from the fruiting bodies of Ganoderma sinense Zhao, Xu et Zhang . Chinese Chemical Letters , 21 : 197 – 199 .
  • Wang , C F , Liu , J Q , Yan , Y X , Chen , J C Lu , Y . 2010 . Three new triterpenoids containing four-membered ring from the fruiting body of Ganoderma sinense . Org Lett , 12 : 1656 – 1659 .
  • Ukai , S , Kiho , T , Hara , C , Morita , M Goto , A . 1983 . Anti-tumor activity of various polysaccharides isolated from Dictyophora indusiata, Ganoderma japonicum, Cordyceps cicadae, Auricularia auricula Judae, and Auricularia Species . Chem Pharm Bull (Tokyo) , 31 : 741 – 744 .
  • Han , X Q , Chan , C L , Dong , C X , Yang , Y H Ko , C H . 2012 . Isolation, structure characterization, and immunomodulating activity of a hyperbranched polysaccharide from the fruiting bodies of Ganoderma sinense . J Agric Food Chem , 60 : 4276 – 4281 .
  • Han , X Q , Chan , B C , Yu , H , Yang , Y H Hu , S Q . 2012 . Structural characterization and immuno-modulating activities of a polysaccharide from Ganoderma sinense . Int J Biol Macromol , 51 : 597 – 603 .
  • Yue , G GL , Fung , K P , Leung , P C and Lau , C BS . 2008 . Comparative studies on the immunomodulatory and antitumor activities of the different parts of fruiting body of Ganoderma lucidum and Ganoderma spores . Phytother Res , 22 : 1282 – 1291 .
  • Romani , N , Reider , D , Heuer , M , Ebner , S Kampgen , E . 1996 . Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability . J Immunol Methods , 196 : 137 – 151 .
  • Conti , L and Gessani , S . 2008 . GM-CSF in the generation of dendritic cells from human blood monocyte precursors: recent advances . Immunobiology , 213 : 859 – 870 .
  • Duff , G W and Atkins , E . 1982 . The inhibitory effect of polymyxin B on endotoxin-induced endogenous pyrogen production . J Immunol Methods , 52 : 333 – 340 .
  • Yue , G GL , Chan , B CL , Hon , P M , Kennelly , E J Yeung , S K . 2010 . Immunostimulatory activities of polysaccharide extract isolated from Curcuma longa . Int J Biol Macromol , 47 : 342 – 347 .
  • Needs , P W and Selvendran , R R . 1993 . Avoiding oxidative degradation during sodium hydroxide/methyl iodide-mediated carbohydrate methylation in dimethyl sulfoxide . Carbohydr Res , 245 : 1 – 10 .
  • Sweet , D P , Shapiro , R H and Albersheim , P . 1995 . Quantitative analysis by various g.l.c. response factor theories for partially methylated and partially ethylated alditol acetates . Carbohydr Res , 40 : 217 – 225 .
  • Sato , N , Zhang , Q , Ma , C M and Hattori , M . 2009 . Anti-human immunodeficiency virus-1 protease activity of new lanostane-type triterpenoids from Ganoderma sinense . Chem Pharm Bull (Tokyo) , 57 : 1076 – 1080 .
  • Banchereau , J and Steinman , R M . 1998 . Dendritic cells and the control of immunity . Nature , 392 : 245 – 252 .
  • Morisaki , T , Matsumoto , K , Onishi , H , Kuroki , H Baba , E . 2003 . Dendritic cell-based combined immunotherapy with autologous tumor-pulsed dendritic cell vaccine and activated T cells for cancer patients: rationale, current progress, and perspectives . Hum Cell , 16 : 175 – 182 .
  • Shimizu , K and Fujii , S . 2008 . An adjuvant role of in situ dendritic cells (DCs) in linking innate and adaptive immunity . Front Biosci , 13 : 6193 – 6201 .
  • Chan , W K , Law , H K , Lin , Z B , Lau , Y L and Chan , G C . 2007 . Response of human dendritic cells to different immunomodulatory polysaccharides derived from mushroom and barley . Int Immunol , 19 : 891 – 899 .
  • Hsu , H Y , Hua , K F , Lin , C C , Lin , C H Hsu , J . 2004 . Extract of Reishi polysaccharides induces cytokine expression via TLR4-modulated protein kinase signaling pathways . J Immunol , 173 : 5989 – 5999 .
  • Li , X and Xu , W . 2011 . TLR4-mediated activation of macrophages by the polysaccharide fraction from Polyporus umbellatus (pers.) Fries . J Ethnopharmacol , 135 : 1 – 6 .
  • Lin , Y L , Lee , S S , Hou , S M and Chiang , B L . 2006 . Polysaccharide purified from Ganoderma lucidum induces gene expression changes in human dendritic cells and promotes T helper 1 immune response in BALB/c mice . Mol Pharmacol , 70 : 637 – 644 .
  • Whiteside , T L , Stanson , J , Shurin , M R and Ferrone , S . 2004 . Antigen-processing machinery in human dendritic cells: up-regulation by maturation and down-regulation by tumor cells . J Immunol , 173 : 1526 – 1534 .
  • Zhao , H , Luo , Y , Lu , C , Lin , N Xiao , C . 2010 . Enteric mucosal immune response might trigger the immunomodulation activity of Ganoderma lucidum polysaccharide in mice . Planta Med , 76 : 223 – 227 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.