Procyanidin Induces Apoptosis of Esophageal Adenocarcinoma Cells via JNK Activation of c-Jun

REFERENCES

• Powell , J , McConkey , C C , Gillison , E W and Spychal , R T . 2002 . Continuing rising trend in oesophageal adenocarcinoma . Int J Cancer , 102 : 422 – 427 .
   PubMed Web of Science ®Google Scholar
• Jankowski , J A , Perry , I and Harrison , R F . 2000 . Gastro-oesophageal cancer: death at the junction . BMJ , 321 : 463 – 464 .
   PubMed Web of Science ®Google Scholar
• Brown , L M , Swanson , C A , Gridley , G , Swanson , G M Schoenberg , J B . 1995 . Adenocarcinoma of the esophagus: role of obesity and diet . J Natl Cancer Inst , 87 : 104 – 109 .
   PubMed Web of Science ®Google Scholar
• Zhang , Z F , Kurtz , R C , Yu , G P , Sun , M Gargon , N . 1997 . Adenocarcinomas of the esophagus and gastric cardia: the role of diet . Nutr Cancer , 27 : 298 – 309 .
   PubMed Web of Science ®Google Scholar
• Kabat , G C , Ng , S K and Wynder , E L . 1993 . Tobacco, alcohol intake, and diet in relation to adenocarcinoma of the esophagus and gastric cardia . Cancer Causes Control , 4 : 123 – 132 .
   PubMed Web of Science ®Google Scholar
• Anderson , L A , Watson , R G , Murphy , S J , Johnston , B T Comber , H . 2007 . Risk factors for Barrett's oesophagus and oesophageal adenocarcinoma: results from the FINBAR study . World J Gastroenterol , 13 : 1585 – 1594 .
   PubMed Web of Science ®Google Scholar
• Mehta , S , Johnson , I T and Rhodes , M . 2005 . Systematic review: the chemoprevention of oesophageal adenocarcinoma . Aliment Pharmacol Ther , 22 : 759 – 768 .
   PubMed Web of Science ®Google Scholar
• Prior , R L and Gu , L . 2005 . Occurrence and biological significance of proanthocyanidins in the American diet . Phytochemistry , 66 : 2264 – 2280 .
   PubMed Web of Science ®Google Scholar
• Raina , K , Singh , R P , Agarwal , R and Agarwal , C . 2007 . Oral grape seed extract inhibits prostate tumor growth and progression in TRAMP mice . Cancer Res , 67 : 5976 – 5982 .
   PubMed Web of Science ®Google Scholar
• Gosse , F , Guyot , S , Roussi , S , Lobstein , A Fischer , B . 2005 . Chemopreventive properties of apple procyanidins on human colon cancer-derived metastatic SW620 cells and in a rat model of colon carcinogenesis . Carcinogenesis , 26 : 1291 – 1295 .
   PubMed Web of Science ®Google Scholar
• Ramljak , D , Romanczyk , L J , Metheny-Barlow , L J , Thompson , N Knezevic , V . 2005 . Pentameric procyanidin from Theobroma cacao selectively inhibits growth of human breast cancer cells . Mol Cancer Ther , 4 : 537 – 546 .
   PubMed Web of Science ®Google Scholar
• Seeram , N P , Adams , L S , Hardy , M L and Heber , D . 2004 . Total cranberry extract versus its phytochemical constituents: antiproliferative and synergistic effects against human tumor cell lines . J Agric Food Chem , 52 : 2512 – 2517 .
   PubMed Web of Science ®Google Scholar
• Carnesecchi , S , Schneider , Y , Lazarus , S A , Coehlo , D Gosse , F . 2002 . Flavanols and procyanidins of cocoa and chocolate inhibit growth and polyamine biosynthesis of human colonic cancer cells . Cancer Lett , 175 : 147 – 155 .
   PubMed Web of Science ®Google Scholar
• Pierini , R , Kroon , P A , Guyot , S , Ivory , K Johnson , I T . 2008 . Procyanidin effects on oesophageal adenocarcinoma cells strongly depend on flavan-3-ol degree of polymerization . Mol Nutr Food Res , 52 : 1399 – 1407 .
   PubMed Web of Science ®Google Scholar
• Pierini , R , Kroon , P A , Guyot , S , Johnson , I T and Belshaw , N J . 2008 . The procyanidin-mediated induction of apoptosis and cell-cycle arrest in esophageal adenocarcinoma cells is not dependent on p21(Cip1/WAF1) . Cancer Lett , 270 : 234 – 241 .
   PubMed Web of Science ®Google Scholar
• Dhillon , A S , Hagan , S , Rath , O and Kolch , W . 2007 . MAP kinase signalling pathways in cancer . Oncogene , 26 : 3279 – 3290 .
   PubMed Web of Science ®Google Scholar
• Kwon , K H , Barve , A , Yu , S , Huang , M T and Kong , A N . 2007 . Cancer chemoprevention by phytochemicals: potential molecular targets, biomarkers and animal models . Acta Pharmacol Sin , 28 : 1409 – 1421 .
   PubMed Web of Science ®Google Scholar
• Kang , N J , Lee , K W , Lee , D E , Rogozin , E A Bode , A M . 2008 . Cocoa procyanidins suppress transformation by inhibiting mitogen-activated protein kinase kinase . J Biol Chem , 283 : 20664 – 20673 .
   PubMed Web of Science ®Google Scholar
• Eady , J J , Wortley , G M , Wormstone , Y M , Hughes , J C Astley , S B . 2005 . Variation in gene expression profiles of peripheral blood mononuclear cells from healthy volunteers . Physiol Genomics , 22 : 402 – 411 .
   PubMed Web of Science ®Google Scholar
• Smyth , G K . 2004 . Linear models and empirical bayes methods for assessing differential expression in microarray experiments . Stat Appl Genet Mol Biol , 3 ( Article 3 )
   PubMedGoogle Scholar
• Werner , T . 2001 . Target gene identification from expression array data by promoter analysis . Biomol Eng , 17 : 87 – 94 .
   PubMedGoogle Scholar
• Hibi , M , Lin , A , Smeal , T , Minden , A and Karin , M . 1993 . Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain . Genes Dev , 7 : 2135 – 2148 .
   PubMed Web of Science ®Google Scholar
• Hazzalin , C A , Cano , E , Cuenda , A , Barratt , M J Cohen , P . 1996 . p38/RK is essential for stress-induced nuclear responses: JNK/SAPKs and c-Jun/ATF-2 phosphorylation are insufficient . Curr Biol , 6 : 1028 – 1031 .
   PubMed Web of Science ®Google Scholar
• Yamagishi , S , Yamada , M , Ishikawa , Y , Matsumoto , T Ikeuchi , T . 2001 . p38 mitogen-activated protein kinase regulates low potassium-induced c-Jun phosphorylation and apoptosis in cultured cerebellar granule neurons . J Biol Chem , 276 : 5129 – 5133 .
   PubMed Web of Science ®Google Scholar
• Shaulian , E and Karin , M . 2002 . AP-1 as a regulator of cell life and death . Nat Cell Biol , 4 : E131 – E136 .
   PubMed Web of Science ®Google Scholar
• Karin , M . 1996 . The regulation of AP-1 activity by mitogen-activated protein kinases . Philos Trans R Soc Lond B Biol Sci , 351 : 127 – 134 .
   PubMed Web of Science ®Google Scholar
• Saeki , K , Kobayashi , N , Inazawa , Y , Zhang , H Nishitoh , H . 2002 . Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor-mediated apoptosis . Biochem J , 368 : 705 – 720 .
   PubMed Web of Science ®Google Scholar
• She , Q B , Huang , C , Zhang , Y and Dong , Z . 2002 . Involvement of c-jun NH(2)-terminal kinases in resveratrol-induced activation of p53 and apoptosis . Mol Carcinog , 33 : 244 – 250 .
   PubMed Web of Science ®Google Scholar
• Miao , Z H and Ding , J . 2003 . Transcription factor c-Jun activation represses mdr-1 gene expression . Cancer Res , 63 : 4527 – 4532 .
   PubMed Web of Science ®Google Scholar
• Baltriukiene , D , Kalvelyte , A and Bukelskiene , V . 2007 . Induction of apoptosis and activation of JNK and p38 MAPK pathways in deoxynivalenol-treated cell lines . Altern Lab Anim , 35 : 53 – 59 .
   PubMed Web of Science ®Google Scholar
• Bossy-Wetzel , E , Bakiri , L and Yaniv , M . 1997 . Induction of apoptosis by the transcription factor c-Jun . EMBO J , 16 : 1695 – 1709 .
   PubMed Web of Science ®Google Scholar
• Podar , K , Raab , M S , Tonon , G , Sattler , M Barila , D . 2007 . Up-regulation of c-Jun inhibits proliferation and induces apoptosis via caspase-triggered c-Abl cleavage in human multiple myeloma . Cancer Res , 67 : 1680 – 1688 .
   PubMed Web of Science ®Google Scholar
• Tournier , C , Hess , P , Yang , D D , Xu , J Turner , T K . 2000 . Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway . Science , 288 : 870 – 874 .
   PubMed Web of Science ®Google Scholar
• Lei , K and Davis , R J . 2003 . JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis . Proc Natl Acad Sci U S A , 100 : 2432 – 2437 .
   PubMed Web of Science ®Google Scholar
• Lu , Q P and Tian , L . 2005 . Fas mRNA expression and calcium influx change in H2O2-induced apoptotic hepatocytes in vitro . World J Gastroenterol , 11 : 534 – 537 .
   PubMed Web of Science ®Google Scholar
• Basu , A and Haldar , S . 2008 . Dietary isothiocyanate mediated apoptosis of human cancer cells is associated with Bcl-xL phosphorylation . Int J Oncol , 33 : 657 – 663 .
   PubMed Web of Science ®Google Scholar