2’-Hydroxyflavanone Induces Apoptosis of Human Osteosarcoma 143 B Cells by Activating the Extrinsic TRAIL- and Intrinsic Mitochondria-Mediated Pathways

REFERENCES

• Fotsis T, Pepper MS, Aktas E, Breit S, Rasku S, et al.: Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis. Cancer Res 57, 2916–2921, 1997.
   PubMed Web of Science ®Google Scholar
• Plaumann B, Fritsche M, Rimpler H, Brandner G, and Hess RD: Flavonoids activate wild-type p53. Oncogene 13, 1605–1614, 1996.
   PubMed Web of Science ®Google Scholar
• Havsteen B: Flavonoids, a class of natural products of high pharmacological potency. Biochem Pharmacol 32, 1141–1148, 1983.
   PubMed Web of Science ®Google Scholar
• Cheng TC, Lu JF, Wang JS, Lin LJ, Kuo HI, et al.: Antiproliferation effect and apoptosis mechanism of prostate cancer cell PC-3 by flavonoids and saponins prepared from Gynostemma pentaphyllum. J Agric Food Chem 59, 11319–11329, 2011.
   PubMed Web of Science ®Google Scholar
• Choi SH, Ahn JB, Kim HJ, Im NK, Kozukue N, et al.: Changes in free amino acid, protein, and flavonoid content in jujube (Ziziphus jujube) fruit during eight stages of growth and antioxidative and cancer cell inhibitory effects by extracts. J Agric Food Chem 60, 10245–10255, 2012.
   PubMed Web of Science ®Google Scholar
• Ni F, Gong Y, Li L, Abdolmaleky HM, and Zhou JR: Flavonoid ampelopsin inhibits the growth and metastasis of prostate cancer in vitro and in mice. PLoS One 7, e38802, 2012.
   PubMed Web of Science ®Google Scholar
• Ottaviani G and Jaffe N: The epidemiology of osteosarcoma. Cancer Treat Res 152, 3–13, 2009.
   PubMedGoogle Scholar
• Mirabello L, Troisi RJ, and Savage SA: Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program. Cancer 115, 1531–1543, 2009.
   PubMed Web of Science ®Google Scholar
• Oertel S, Blattmann C, Rieken S, Jensen A, Combs SE, et al.: Radiotherapy in the treatment of primary osteosarcoma—a single center experience. Tumori 96, 582–588, 2010.
   PubMed Web of Science ®Google Scholar
• Park H, Bergeron E, Senta H, Guillemette K, Beauvais S, et al.: Sanguinarine induces apoptosis of human osteosarcoma cells through the extrinsic and intrinsic pathways. Biochem Biophys Res Commun 399, 446–451, 2010.
   PubMed Web of Science ®Google Scholar
• Gazitt Y, Kolaparthi V, Moncada K, Thomas C, and Freeman J: Targeted therapy of human osteosarcoma with 17AAG or rapamycin: characterization of induced apoptosis and inhibition of mTOR and Akt/MAPK/Wnt pathways. Int J Oncol 34, 551–561, 2009.
   PubMed Web of Science ®Google Scholar
• Hall MA and Cleveland JL: Clearing the TRAIL for Cancer Therapy. Cancer Cell 12, 4–6, 2007.
   PubMed Web of Science ®Google Scholar
• Almasan A and Ashkenazi A: Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy. Cytokine Growth Factor Rev 14, 337–348, 2003.
   PubMed Web of Science ®Google Scholar
• Chiang PC, Kung FL, Huang DM, Li TK, Fan JR, et al.: Induction of Fas clustering and apoptosis by coral prostanoid in human hormone-resistant prostate cancer cells. Eur J Pharmacol 542, 22–30, 2006.
   PubMed Web of Science ®Google Scholar
• Soriano ME and Scorrano L: The interplay between BCL-2 family proteins and mitochondrial morphology in the regulation of apoptosis. Adv Exp Med Biol 687, 97–114, 2010.
   PubMed Web of Science ®Google Scholar
• Qu M, Zhou Z, Chen C, Li M, Pei L, et al.: Inhibition of mitochondrial permeability transition pore opening is involved in the protective effects of mortalin overexpression against beta-amyloid-induced apoptosis in SH-SY5Y cells. Neurosci Res 72, 94–102, 2012.
   PubMed Web of Science ®Google Scholar
• Mendez G, Policarpi C, Cenciarelli C, Tanzarella C and Antoccia A: Role of Bim in apoptosis induced in H460 lung tumor cells by the spindle poison Combretastatin-A4. Apoptosis 16, 940–949, 2011.
   PubMed Web of Science ®Google Scholar
• Aggarwal BB and Shishodia S: Molecular targets of dietary agents for pre-vention and therapy of cancer. Biochem Pharmacol 71, 1397–1421, 2006.
   PubMed Web of Science ®Google Scholar
• Shi RX, Ong CN, and Shen HM: Protein kinase C inhibition and x-linked inhibitor of apoptosis protein degradation contribute to the sensitization effect of luteolin on tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in cancer cells. Cancer Res 65, 7815–7823, 2005.
   PubMed Web of Science ®Google Scholar
• Horinaka M, Yoshida T, Shiraishi T, Nakata S, Wakada M, et al.: Luteolin induces apoptosis via death receptor 5 upregulation in human malignant tumor cells. Oncogene 24, 7180–7189, 2005.
   PubMed Web of Science ®Google Scholar
• Hsieh YS, Chu SC, Yang SF, Chen PN, Liu YC, et al.: Silibinin suppresses human osteosarcoma MG-63 cell invasion by inhibiting the ERK-dependent c-Jun/AP-1 induction of MMP-2. Carcinogenesis 28, 977–987, 2007.
   PubMed Web of Science ®Google Scholar
• Lu KH, Lue KH, Chou MC, and Chung JG: Paclitaxel induces apoptosis via caspase-3 activation in human osteogenic sarcoma cells (U-2 OS). J Orthop Res 23, 988–994, 2005.
   PubMed Web of Science ®Google Scholar
• Lu KH, Lue KH, Liao HH, Lin KL, and Chung JG: Induction of caspase-3-dependent apoptosis in human leukemia HL-60 cells by paclitaxel. Clin Chim Acta 357, 65–73, 2005.
   PubMed Web of Science ®Google Scholar
• Chien MH, Ying TH, Yang SF, Yu JK, Hsu CW, et al.: Lipocalin-2 induces apoptosis in human hepatocellular carcinoma cells through activation of mitochondria pathways. Cell Biochem Biophys 64, 177–186, 2012.
   PubMed Web of Science ®Google Scholar
• Chen PN, Chu SC, Kuo WH, Chou MY, Lin JK, et al.: Epigallocatechin-3 gallate inhibits invasion, epithelial-mesenchymal transition, and tumor growth in oral cancer cells. J Agric Food Chem 59, 3836–3844, 2011.
   PubMed Web of Science ®Google Scholar
• Orrenius S: Mitochondrial regulation of apoptotic cell death. Toxicol Lett 149, 19–23, 2004.
   PubMed Web of Science ®Google Scholar
• Shakibaei M, Schulze-Tanzil G, Takada Y, and Aggarwal BB: Redox regulation of apoptosis by members of the TNF superfamily. Antioxid Redox Signal 7, 482–496, 2005.
   PubMed Web of Science ®Google Scholar
• Shen HM and Pervaiz S: TNF receptor superfamily-induced cell death: redox-dependent execution. FASEB J 20, 1589–1598, 2006.
   PubMed Web of Science ®Google Scholar
• Baud V and Karin M: Signal transduction by tumor necrosis factor and its relatives. Trends Cell Biol 11, 372–377, 2001.
   PubMed Web of Science ®Google Scholar
• Wajant H, Pfizenmaier K, and Scheurich P: Tumor necrosis factor signaling. Cell Death Differ 10, 45–65, 2003.
   PubMed Web of Science ®Google Scholar
• Kruyt FA: TRAIL and cancer therapy. Cancer Lett 263, 14–25, 2008.
   PubMed Web of Science ®Google Scholar
• Zhang L and Fang B: Mechanisms of resistance to TRAIL-induced apoptosis in cancer. Cancer Gene Ther 12, 228–237, 2005.
   PubMed Web of Science ®Google Scholar
• Herr I and Debatin KM: Cellular stress response and apoptosis in cancer therapy. Blood 98, 2603–2614, 2001.
   PubMed Web of Science ®Google Scholar
• Petit PX, Lecoeur H, Zorn E, Dauguet C, Mignotte B, et al.: Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis. J Cell Biol 130, 157–167, 1995.
   PubMed Web of Science ®Google Scholar
• Leibowitz B and Yu J: Mitochondrial signaling in cell death via the Bcl-2 family. Cancer Biol Ther 9, 417–422, 2010.
   PubMed Web of Science ®Google Scholar
• Eliseev RA, Dong YF, Sampson E, Zuscik MJ, Schwarz EM, et al.: Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivity to apoptosis. Oncogene 27, 3605–3614, 2008.
   PubMed Web of Science ®Google Scholar
• Lim ML, Chen B, Beart PM, and Nagley P: Relative timing of redistribution of cytochrome c and Smac/DIABLO from mitochondria during apoptosis assessed by double immunocytochemistry on mammalian cells. Exp Cell Res 312, 1174–1184, 2006.
   PubMed Web of Science ®Google Scholar