181
Views
12
CrossRef citations to date
0
Altmetric
Original Articles

Tetrandrine and Caffeine Modulated Cell Cycle and Increased Glioma Cell Death via Caspase-Dependent and Caspase-Independent Apoptosis Pathways

, , &
Pages 700-706 | Received 12 May 2013, Accepted 08 Jan 2014, Published online: 16 Apr 2014

REFERENCES

  • Brandsma D and van den Bent MJ: Molecular targeted therapies and chemotherapy in malignant gliomas. Current Opinion in Oncology 19, 598–605, 2007.
  • Krakstad C and Chekenya M: Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics. Mol Cancer 9, 135, 2010.
  • Kögel D, Fulda S, and Mittelbronn M: Therapeutic exploitation of apoptosis and autophagy for glioblastoma. Anticancer Agents Med Chem 10, 438–449, 2010.
  • Lefranc F, Brotchi J, and Kiss R: Possible future issues in the treatment of glioblastomas: special emphasis on cell migration and the resistance of migrating glioblastoma cells to apoptosis. J Clin Oncol 23, 2411–2422, 2005.
  • Lefranc F, Facchini V, and Kiss R: Proautophagic drugs: a novel means to combat apoptosis-resistant cancers, with a special emphasis on glioblastomas. Oncologist 12, 1395–1403, 2007.
  • Lefranc F, Rynkowski M, DeWitte O, and Kiss R: Present and potential future adjuvant issues in high-grade astrocytic glioma treatment. Adv Tech Stand Neurosurg 34, 3–35, 2009.
  • Wu JM, Chen Y, Chen JC, Lin TY, and Tseng SH: Tetrandrine induces apoptosis and growth suppression of colon cancer cells in mice. Cancer Lett 287, 187–195, 2010.
  • Chen Y, Chen JC, and Tseng SH: Tetrandrine suppresses tumor growth and angiogenesis of gliomas in rats. Int J Cancer 124, 2260–2269, 2009.
  • Chen Y and Tseng SH: The potential of tetrandrine against gliomas. Anticancer Agents Med Chem 10, 534–542, 2010.
  • Holick CN, Smith SG, Giovannucci E, and Michaud DS: Coffee, tea, caffeine intake, and risk of adult glioma in three prospective cohort studies. Cancer Epidemiol Biomarkers Prev 19, 39–47, 2010.
  • Michaud DS, Gallo V, Schlehofer B, Tjønneland A, Olsen A, et al.: Coffee and tea intake and risk of brain tumors in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study. Am J Clin Nutr 92, 1145–1150, 2010.
  • Janss AJ, Levow C, Bernhard EJ, Muschel RJ, McKenna WG, et al.: Caffeine and staurosporine enhance the cytotoxicity of cisplatin and camptothecin in human brain tumor cell lines. Exp Cell Res 243, 29–38, 1998.
  • Kang SS, Han KS, Ku BM, Lee YK, Hong J, et al.: Caffeine-mediated inhibition of calcium release channel inositol 1,4,5-trisphosphate receptor subtype 3 blocks glioblastoma invasion and extends survival. Cancer Res 1, 70, 1173–1183, 2010.
  • Ku BM, Lee YK, Jeong JY, Ryu J, Choi J, et al.: Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells. Mol Cells 31, 275–279, 2011.
  • Carvajal LA and Manfredi JJ: Another fork in the road-life or death decision by the tumor suppressor p53. EMBO Rep 14, 414–421, 2013.
  • Dalton LE, Healey E, Irving J, and Marciniak SJ: Phosphoproteins in stress-induced disease. Prog Mol Biol Transl Sci 106, 189–221, 2012.
  • Brewer JW and Diehl JA: PERK mediates cell-cycle exit during the mammalian unfolded protein response. Proc Natl Acad Sci U S A 97, 12625–12630, 2000.
  • Hamanaka RB, Bennett BS, Cullinan SB, and Diehl JA: PERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway. Mol Biol Cell 16, 5493–5501, 2005.
  • Wek RC, Jiang HY, and Anthony TG: Coping with stress: eIF2 kinases and translational control. Biochem Soc Trans 34, 7–11, 2006.
  • Stockwell SR, Platt G, Barrie SE, Zoumpoulidou G, Te Poele RH, et al.: Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling. PLoS One 7, e28568, 2012.
  • Liu Y, László C, Liu Y, Liu W, Chen X, et al.: Regulation of G(1) arrest and apoptosis in hypoxia by PERK and GCN2-mediated eIF2alpha phosphorylation. Neoplasia 12, 61–68, 2010.
  • Tejada S, Lobo MV, García-Villanueva M, Sacristán S, Pérez-Morgado MI, et al.: Eukaryotic initiation factors (eIF) 2alpha and 4E expression, localization, and phosphorylation in brain tumors. J Histochem Cytochem 57, 503–512, 2009.
  • Rosenwald IB, Wang S, Savas L, Woda B, and Pullman J: Expression of translation initiation factor eIF-2alpha is increased in benign and malignant melanocytic and colonic epithelial neoplasms. Cancer 98, 1080–1088, 2003.
  • Wang J, Wang Q, Cui Y, Liu ZY, Zhao W, et al.: Knockdown of cyclin D1 inhibits proliferation, induces apoptosis, and attenuates the invasive capacity of human glioblastoma cells. J Neurooncol 106, 473–484, 2012.
  • Jia W, Loria RM, Park MA, Yacoub A, Dent P, et al.: The neuro-steroid, 5-androstene 3β,17α diol; induces endoplasmic reticulum stress and autophagy through PERK/eIF2α signaling in malignant glioma cells and transformed fibroblasts. Int J Biochem Cell Biol 42, 2019–2029, 2010.
  • England B, Huang T, and Karsy M. Current understanding of the role and targeting of tumor suppressor p53 in glioblastoma multiforme. Tumor Biol 34, 2063–2074.
  • Cho BB and Toledo-Pereyra LH: Caspase-independent programmed cell death following ischemic stroke. J Invest Surg 21, 141–147, 2008.
  • Chen Y, Chen JC, and Tseng SH: Effects of tetrandrine plus radiation on neuroblastoma cells. Anticancer Res 29, 3163–3171, 2009.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.