The Effect of Black Raspberry Extracts on MnSOD Activity in Protection Against Concanavalin A Induced Liver Injury

REFERENCES

• El Serag HB: Hepatocellular carcinoma. N Engl J Med 365, 1118–1127, 2011.
   PubMed Web of Science ®Google Scholar
• El Serag HB: Epidemiology of viral hepatitis and hepatocellular carcinoma. Gastroenterology 142, 1264–1273, 2012.
   PubMed Web of Science ®Google Scholar
• Ivanov AV; Bartosch B, Smirnova OA, Isaguliants MG, and Kochetkov SN: HCV and oxidative stress in the liver. Viruses 5, 439–469, 2013.
   PubMed Web of Science ®Google Scholar
• Min BY, Kim NY, Jang ES, Shin CM, Lee SH, et al.: Ethanol potentiates hepatitis b virus replication through oxidative stress-dependent and -independent transcriptional activation. Biochem Biophys Res Commun 431, 92–97, 2013.
   PubMed Web of Science ®Google Scholar
• Malaguarnera G, Cataudella E, Giordano M, Nunnar G, Chisari G, et al.: Toxic hepatitis in occupational exposure to solvents. World J. Gastroenterol 18, 2756–2766, 2012.
   PubMed Web of Science ®Google Scholar
• Zhu H, Jia Z, Misra H, and Li YR: Oxidative stress and redox signaling mechanisms of alcoholic liver disease: updated experimental and clinical evidence. J Dig Dis 13, 133–142, 2012.
   PubMed Web of Science ®Google Scholar
• Xiao J, Ho CT, Liong EC, Nanji AA, Leung TM, et al.: Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways. Eur J Nutr 52, 179–191, 2013.
   PubMed Web of Science ®Google Scholar
• Tanaka S, Miyanishi K, Kobune M, Kawano Y, Hoki T, et al.: Increased hepatic oxidative DNA damage in patients with nonalcoholic steatohepatitis who develop hepatocellular carcinoma. J Gastroenterol 19, 71–78, 2013.
   Google Scholar
• Choi J: Oxidative stress, endogenous antioxidants, alcohol, and hepatitis C: pathogenic interactions and therapeutic considerations. Free Radic Biol Med 52, 1135–1150, 2012.
   PubMed Web of Science ®Google Scholar
• Levent G, Ali A, Ahmet A, Polat EC, Aytac C, et al.: Oxidative stress and antioxidant defense in patients with chronic hepatitis c patients before and after pegylated interferon Alfa-2b plus ribavirin therapy. J Transl Med 4, 25.
   Web of Science ®Google Scholar
• Reddy L, Odhav B, and Bhoola KD: Natural products for cancer prevention: a global perspective. Pharmacol Ther 99, 1–13, 2003.
   PubMed Web of Science ®Google Scholar
• Stoner GD, Wang LS, Zikri N, Chen T, Hecht SS, et al.: Cancer prevention with freeze-dried berries and berry components. Semin Cancer Biol 17, 403–410, 2007.
   PubMed Web of Science ®Google Scholar
• Madhusoodhanan R, Natarajan M, Singh JV, Jamgade A, Awasthi V, et al.: Effect of black raspberry extract in inhibiting NFkappa B dependent radioprotection in human breast cancer cells. Nutr Cancer 62, 93–104, 2010.
   PubMed Web of Science ®Google Scholar
• Bi X, Fang W, Wang LS; Stoner GD, and Yang W: Black raspberries inhibit intestinal tumorigenesis in Apc1638+/− and Muc2−/− mouse models of colorectal cancer. Cancer Prev Res (Phila) 3, 1443–1450, 2010.
   PubMed Web of Science ®Google Scholar
• Hecht SS, Huang C, Stoner GD, Li J, Kenney PM, et al.: Identification of cyanidin glycosides as constituents of freeze-dried black raspberries which inhibit anti-benzo[a]pyrene-7,8-diol-9,10-epoxide induced NFkappaB and AP-1 activity. Carcinogenesis 27, 1617–1626, 2006.
   PubMed Web of Science ®Google Scholar
• Stoner GD: Foodstuffs for preventing cancer: the preclinical and clinical development of berries. Cancer Prev Res (Phila) 2, 187–194, 2009.
   PubMed Web of Science ®Google Scholar
• Seeram NP: Berry Fruits for Cancer Prevention: Current Status and Future Prospects. J Agric Food Chem 56, 630–635, 2008.
   PubMed Web of Science ®Google Scholar
• Chang CP, Yang MC, Liu HS, Lin YS, and Lei HY: Concanavalin A induces autophagy in hepatoma cells and has a therapeutic effect in a murine in situ hepatoma model. Hepatology 45, 286–296, 2007.
   PubMed Web of Science ®Google Scholar
• Montrose DC, Horelik NA, Madigan JP, Stoner GD, Wang LS, et al.: Anti-inflammatory effects of freeze-dried black raspberry powder in ulcerative colitis. Carcinogenesis 32, 343–350, 2011.
   PubMed Web of Science ®Google Scholar
• Sun Q, Gao W, Loughran P, Shapiro R, Fan J, et al.: Caspase-1 activation is protective against hepatocyte cell death by up-regulating beclin1 and mitochondrial autophagy in the setting of redox stress. J Biol Chem 45, 588–597, 2013.
   Google Scholar
• Tudek B and Speina E: Oxidatively damaged DNA and its repair in colon carcinogenesis. Mutat Res 736, 82–92, 2012.
   PubMed Web of Science ®Google Scholar
• Aiyer HS, Kichambare S, and Gupta RC: Prevention of oxidative DNA damage by bioactive berry components. Nutr Cancer 60(Suppl. 1), 36–42, 2008. doi:10.1080/01635580802398448
   PubMed Web of Science ®Google Scholar
• Tiegs G, Hentschel J, and Wendel A. A T cell-dependent experimental liver injury in mice inducible by concanavalin A. J Clin Invest 90, 196–203, 1992.
   PubMed Web of Science ®Google Scholar
• Jaruga B, Hong F, Sun R, Radaeva S, and Gao B: Crucial role of IL-4/STAT6 in T cell-mediated hepatitis: up-regulating eotaxins and IL-5 and recruiting leukocytes. J Immunol 171, 3233–3244, 2003.
   PubMed Web of Science ®Google Scholar
• Gantner F, Leist M, Lohse AW, Germann PG, and Tiegs G: Concanavalin A-induced T-cell-mediated hepatic injury in mice: the role of tumor necrosis factor. Hepatology 21, 190–198, 1995.
   PubMed Web of Science ®Google Scholar
• Mizuhara H, Uno M, Seki N, Yamashita M, Yamaoka M, et al.: Critical involvement of interferon gamma in the pathogenesis of t-cell activation-associated hepatitis and regulatory mechanisms of interleukin-6 for the manifestations of hepatitis. Hepatology 23, 1608–1615, 1996.
   PubMed Web of Science ®Google Scholar
• Dasgupta J, Subbaram S, Connor KM, Rodriguez AM, Tirosh O, et al.: Manganese superoxide dismutase protects from TNF-alpha-induced apoptosis by increasing the steady-state production of H2O2. Antioxid Redox Signal 8, 1295–1305, 2006.
   PubMed Web of Science ®Google Scholar
• Pardo M and Tirosh O: Protective signalling effect of manganese superoxide dismutase in hypoxia-reoxygenation of hepatocytes. Free Radic Res 43, 1225–1239, 2009.
   PubMed Web of Science ®Google Scholar
• Li Y, Reuter N, Li XS, and Martin RC: Manganese superoxide dismutase chemoprevention in a murine hepatitis associated injury model. Journal of Cancer Therapy 2, 431–440, 2011.
   Google Scholar
• Wang LS, Hecht SS, Carmella SG, Yu N, Larue B, et al.: Anthocyanins in black raspberries prevent esophageal tumors in rats. Cancer Prev Res (Phila) 2, 84–93, 2009.
   PubMed Web of Science ®Google Scholar
• Aiyer HS, Li Y, Liu QH, Reuter N, and Martin RC: Dietary freeze-dried black raspberry's effect on cellular antioxidant status during reflux-induced esophagitis in rats. Nutrition 27, 182–187, 2011.
   PubMed Web of Science ®Google Scholar
• Aiyer HS, Li Y, Losso JN, Gao C, Schiffman SC, et al.: Effect of freeze-dried berries on the development of reflux-induced esophageal adenocarcinoma. Nutr Cancer 63, 1256–1262, 2011.
   PubMed Web of Science ®Google Scholar
• Ross HA, McDougall GJ, and Stewart D: Antiproliferative activity is predominantly associated with ellagitannins in raspberry extracts. Phytochemistry 68, 218–228, 2007.
   PubMed Web of Science ®Google Scholar