233
Views
10
CrossRef citations to date
0
Altmetric
Original Articles

Terpenoids Isolated From the Shoot of Plectranthus hadiensis Induces Apoptosis in Human Colon Cancer Cells Via the Mitochondria-Dependent Pathway

&
Pages 697-705 | Received 13 Mar 2014, Accepted 18 Nov 2014, Published online: 02 Apr 2015

REFERENCES

  • Thoppil RJ and Bishayee A: Terpenoids as potential chemopreventive and therapeutic agents in liver cancer. World J Hepatol 3, 228–249, 2011.
  • Huang J, Wu L, Tashiro S, Onodera S, and Ikejima T: Reactive oxygen species mediate oridonin induced HepG2 apoptosis through p53, MAPK, and mitochondrial signaling pathways. J Pharmacol Sci 107, 370–379, 2008.
  • Carnesecchi S, Schneider Y, Ceraline J, Duranton B, Gosse F, et al.: Geraniol, a component of plant essential oils, inhibits growth and polyamine biosynthesis in human colon cancer cells. J Pharmacol Exp Ther 298, 197–200, 2001.
  • Carnesecchi S, Bradaia A, Fischer B, Coelho D, Schöller-Guinard M, et al.: Perturbation by geraniol of cell membrane permeability and signal transduction pathways in human colon cancer cells. J Pharmacol Exp Ther 303, 711–715, 2002.
  • Carnesecchi S, Langley K, Exinger F, Gosse F, and Raul F: Geraniol, a component of plant essential oils, sensitizes human colonic cancer cells to 5-Fluorouracil treatment. J Pharmacol Exp Ther 301, 625–630, 2002.
  • Mosmann T: Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of Immunological Methods 65, 55–63, 1983.
  • Kasibhatla S, Amarante-Mendes GP, Finucane D, Brunner T, Bossy-Wetzel E, et al.: Acridine orange/ethidium bromide (AO/EB) staining to detect apoptosis. CSH Protoc 3, 2006.
  • Vidhya N and Devaraj SN: Induction of apoptosis by eugenol in human breast cancer cells. Indian J Exp Biol 49, 871–878, 2011.
  • Moser FG, Dorman BP, and Ruddle FH: Mouse-human heterokaryon analysis with 33258 Hoechst-Giemsa technique. J Cell Biol 66, 676–680, 1975.
  • Latt SA and Stetten G: Spectral studies on 33258 Hoechst and related bisbenzimidazole dyes useful for fluorescent detection of deoxyribonucleic acid synthesis. J Histochem Cytochem 24, 24–33, 1976.
  • Avishai N, Rabinowitz C, Moiseeva E, and Rinkevich B: Genotoxicity of the Kishon River, Israel: the application of an in vitro cellular assay. Mutat Res 518, 21–37, 2002.
  • Shylesh BS, Nair SA, and Subramoniam A: Induction of cell-specific apoptosis and protection from Dalton's lymphoma challenge in mice by an active fraction from Emilia sonchifolia. Indian J Pharmacol 37, 232–237, 2005.
  • Xu G, Ahn J, Chang S, Eguchi M, Ogier A, et al.: Lipocalin2 induces cardiomyocyte apoptosis by increasing intracellular iron accumulation. J Biol Chem 287, 4808–4817, 2012.
  • Hans-Joachim D, Annette D, Grünewald-Janho ED, and Joe SK: PCR Applications Manual (3rd ed.). Roche Diagnostics, Mannheim, Germany, 2006.
  • Xi L, Nicastri DG, El-Hefnawy T, Hughes SJ, Luketich JD, et al.: Optimal markers for real-time quantitative reverse transcription PCR detection of circulating tumor cells from melanoma, breast, colon, esophageal, head and neck, and lung cancers. Clin Chem 53, 1206–1215, 2007.
  • Hsu YT and Youle RJ: Nonionic detergents induce dimerization among members of the Bcl-2 family. J Biol Chem 272, 13829–13834, 1997.
  • Sambrook J, Fritsch EF, and Maniatis T: Molecular Cloning: a laboratory manual (2nd ed.) Cold Spring Harbor Laboratory, NY: Cold Spring Harbor Laboratory Press, 1989.
  • Eslami A and Lujan J: Western blotting: sample preparation to detection. J Vis Exp. 44, 2359, 2010.
  • Lukhoba CW, Simmonds MSJ, and Paton AJ: Plectranthus: A review of ethnobotanical uses. J of Ethnopharmacol 103, 1–24, 2006.
  • Loken MR: Simultaneous quantitation of Hoechst 33342 and immunofluorescence on viable cells using a fluorescence activated cell sorter. Cytometry 1, 136–142, 1980.
  • Wong VWC, Szeto YT, Collins AR, and Benzie IFF: The comet assay: A biomonitoring tool for nutraceutical research. Curr Top Nutraceutical Res 3, 1–14, 2005.
  • Gerschenson LE and Rotello RJ: Apoptosis: a different type of cell death. FASEB J 6, 2450–2455, 1992.
  • Wyllie AH: Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284 555–556, 1980.
  • Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, et al.: A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 391, 43–50, 1998.
  • Iwata M, Myerson D, Torok-Storb B, and Zager RA: An evaluation of renal tubular DNA laddering in response to oxygen deprivation and oxidant injury. J Am Soc Nephrol 5, 1307–1313, 1994.
  • Lazebnik YA, Kaufmann SH, Desnoyers S, Pirier GG, and Earnshaw WC: Cleavage of poly (ADP ribose) polymerase by a proteinase with properties like ICE. Nature 371, 346–347, 1994.
  • Eberhart CE, Coffey RJ, Radhika A, Giardiello FM, Ferrenbach S, et al.: Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas. Gastroenterology 107, 1183–1188, 1994.
  • Kargman S, O'Neill GP, Vickers PJ, Evans JF, Mancini JA, et al.: Expression of prostaglandin G/H synthase-1 and −2 protein in human colon cancer. Cancer Res 55, 2556–2559, 1995.
  • Sano H, Kawahito Y, Wilder RL, Hashiramoto A, Mukai S, et al.: Expression of cyclooxygenase-1 and −2 in human colorectal cancer. Cancer Res 55, 3785–3789, 1995.
  • Gustafson-Svärd C, Lilja I, Hallböök O, and Sjödahl R: Cyclooxygenase-1 and cyclooxygenase-2 gene expression in human colorectal adenocarcinomas and in azoxymethane induced colonic tumours in rats. Gut 38, 79–84, 1996.
  • Bennett A, Charlier EM, McDonald AM, Simpson JS, Stamford IF, et al.: Prostaglandins and breast cancer. Lancet 2, 624–626, 1977.
  • Tsujii M and DuBois RN: Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2. Cell 83, 493–501, 1995.
  • Tsujii M, Kawano S, and DuBois RN: Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential. Proc Natl Acad Sci USA 94, 3336–3340, 1997.
  • Wiese FW, Thompson PA, and Kadlubar FF: Carcinogen substrate specificity of human COX-1 and COX-2. Carcinogenesis. 22, 5–10, 2001.
  • Dubois RN, Abramson SB, Crofford L, Gupta RA, Simon LS, et al.: Cyclooxygenase in biology and disease. FASEB J 12, 1063–1073, 1998.
  • Cleary ML, Smith SD, and Sklar J: Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation. Cell 47, 19–28, 1986.
  • Seto M, Jaeger U, Hockett RD, Graninger W, Bennett S, et al.: Alternative promoters and exons, somatic mutation and deregulation of the bcl-2-Ig fusion gene in lymphomas. EMBO J 7, 123–131, 1988.
  • Vaux DL, Cory S, and Adams JM: Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 335, 440–442, 1988.
  • Jaattela M: Escaping cell death: survival proteins in cancer. Exp Cell Res 248, 30–43, 1999.
  • Akao Y, Otsuki Y, Kataoka S, Ito Y, and Tsujimoto Y: Multiple subcellular localization of bcl-2: Detection in nuclear outer membrane, endoplasmic reticulum, and mitochondrial membranes. Cancer Res 54, 2468–2471, 1994.
  • Adams JM and Cory S: The Bcl-2 protein family: arbiters of cell survival. Science 281, 1322–1326, 1998.
  • Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, and Korsmeyer SJ: Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75, 241–251, 1993.
  • Hockenbery DM, Giedt CD, O'Neill JW, Manion MK, and Banker DE: Mitochondria and apoptosis: new therapeutic targets. Advance Cancer Research 85, 203–242, 2002.
  • Wyllie AH: Apoptosis: cell death in tissue regulation. J Pathol 153, 313–316, 1987.
  • Yang J, Liu X, Bhalla K, Kim CN, Ibrado AM, et al.: Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 275, 1129–1132, 1997.
  • Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, et al.: Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479–489, 1997.
  • Cai J, Yang J, and Jones DP: Mitochondrial control of apoptosis: the role of cytochrome c. Biochim Biophys Acta 1366, 139–149, 1998.
  • Pellegrini M and Strasser A: A portrait of the Bcl-2 protein family: life, death and the whole picture. J Clin Immunol 19, 365–377, 1999.
  • Bronner MP, Culin C, Reed JC, and Furth EE: The bcl-2 proto-oncogene and the gastrointestinal epithelial tumor progression model. Am J Pathol. 146, 20–26, 1995.
  • Huerta S, Goulet EJ, and Livingston EH: Colon cancer and apoptosis. Am J Surg 191, 517–526, 2006.
  • Poincloux L, Durando X, Seitz JF, Thivat E, Bardou VJ, et al.: Loss of Bcl-2 expression in colon cancer: a prognostic factor for recurrence in stage II colon cancer. Surg Oncol 18, 357–365, 2009.
  • Miquel C, Borrini F, Grandjouan S, Auperin A, Viguier J, et al.: Role of bax mutations in apoptosis in colorectal cancers with microsatellite instability. Anatomic Pathology 123, 562–570, 2005.
  • Aggarwal BB, Prasad S, Reuter S, Kannapan R, Yadav VR, et al.: Identification of novel anti-inflammatory agents from Ayurvedic medicine for prevention of chronic diseases: “Reverse Pharmacology” and “Bedside to Bench” approach. Current Drug Targets 12, 1595–1653, 2011.
  • Cristophe W: Lead compounds from medicinal plants for the treatment of cancer (2nd ed.). Waltham, MA: Academic Press, 2006.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.