An Immune-Modulating Diet in Combination with Chemotherapy Prevents Cancer Cachexia by Attenuating Systemic Inflammation in Colon 26 Tumor-Bearing Mice

REFERENCES

• Fearon K, Strasser F, Anker SD, Bosaeus I, Bruera E, et al.: Definition and classification of cancer cachexia: an international consensus. Lancet Oncol 12, 489–495, 2011.
   PubMed Web of Science ®Google Scholar
• Prado CMM, Lieffers JR, McCargar LJ, Reiman T, Sawyer MB, et al.: Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study. Lancet Oncol 9, 629–635, 2008.
   PubMed Web of Science ®Google Scholar
• Isenring EA, Capra S, and Bauer JD: Nutrition intervention is beneficial in oncology outpatients receiving radiotherapy to the gastrointestinal or head and neck area. Br J Cancer 91, 447–452, 2004.
   PubMed Web of Science ®Google Scholar
• Ravasco P, Monteiro-Grillo I, Marques Vidal P, and Camilo ME: Impact of nutrition on outcome: A prospective randomized controlled trial in patients with head and neck cancer undergoing radiotherapy. Head & Neck 27, 659–668, 2005.
   PubMed Web of Science ®Google Scholar
• Arends J, Bodoky G, Bozzetti F, Fearon K, Muscaritoli M, et al.: ESPEN Guidelines on Enteral Nutrition: Non-surgical oncology. Clin Nutr 25, 245–259, 2006.
   PubMed Web of Science ®Google Scholar
• Tisdale MJ: Mechanisms of Cancer Cachexia. Physiol Rev 89, 381–410, 2009.
   PubMed Web of Science ®Google Scholar
• Deans C and Wigmore SJ: Systemic inflammation, cachexia and prognosis in patients with cancer. Curr Opin Clin Nutr Metab Care 8, 265–269, 2005.
   PubMed Web of Science ®Google Scholar
• Hambek M, Baghi M, Wagenblast J, Schmitt J, Baumann H, et al.: Inverse correlation between serum PGE2 and T classification in head and neck cancer. Head & Neck 29, 244–248, 2007.
   PubMed Web of Science ®Google Scholar
• Martín F, Santolaria F, Batista N, Milena A, González-Reimers E, et al.: Cytokine levels (IL-6 and IFN-γ), acute phase response and nutritional status as prognostic factors in lung cancer. Cytokine 11, 80–86, 1999.
   PubMed Web of Science ®Google Scholar
• Ravasco P, Monteiro-Grillo I, and Camilo M: How Relevant Are Cytokines in Colorectal Cancer Wasting? Cancer J 13, 392–398, 2007.
   PubMed Web of Science ®Google Scholar
• Fearon K: Cancer cachexia: developing multimodal therapy for a multidimensional problem. Eur J Cancer 44, 1124–1132, 2008.
   PubMed Web of Science ®Google Scholar
• Baldwin C: Nutritional support for malnourished patients with cancer. Curr Opin Support Palliat Care 5, 29–36., 2011.
   PubMedGoogle Scholar
• Pontes-Arruda A, DeMichele S, Seth A, and Singer P: The use of an inflammation-modulating diet in patients with acute lung injury or acute respiratory distress syndrome: a meta-analysis of outcome data. JPEN J Parenter Enteral Nutr 32, 596–605, 2008.
   PubMed Web of Science ®Google Scholar
• Kume H, Okazaki K, Yamaji T, and Sasaki H: A newly designed enteral formula containing whey peptides and fermented milk product protects mice against concanavalin A-induced hepatitis by suppressing overproduction of inflammatory cytokines. Clin Nutr 31, 283–289, 2012.
   PubMed Web of Science ®Google Scholar
• Nakamura K, Ogawa S, Dairiki K, Fukatsu K, Sasaki H, et al.: A new immune-modulating diet enriched with whey-hydrolyzed peptide, fermented milk, and isomaltulose attenuates gut ischemia-reperfusion injury in mice. Clin Nutr 30, 513–516, 2011.
   PubMed Web of Science ®Google Scholar
• Kaido T, Mori A, Ogura Y, Hata K, Yoshizawa A, et al.: Impact of enteral nutrition using a new immuno-modulating diet after liver transplantation. Hepatogastroenterology 57, 1522–1525, 2010.
   PubMed Web of Science ®Google Scholar
• Kaido T, Ogura Y, Ogawa K, Hata K, Yoshizawa A, et al.: Effects of post-transplant enteral nutrition with an immunomodulating diet containing hydrolyzed whey peptide after liver transplantation. World J Surg 36, 1666–1671, 2012.
   PubMed Web of Science ®Google Scholar
• Ishikawa D, Shimada M, Utsunomiya T, Imura S, Morine Y, et al.: Whey protein isolate, MEIN (R), can reduce liver damage early after living donor liver transplantation. Transplant International 24, 311, 2011.
   Web of Science ®Google Scholar
• Dong J, Yang J, Chen M, Wang X, Wu Z, et al.: A comparative study of gene vaccines encoding different extracellular domains of the vascular endothelial growth factor receptor 2 in the mouse model of colon adenocarcinoma CT-26. Cancer Biol Ther 7, 502–509, 2008.
   PubMed Web of Science ®Google Scholar
• Strassmann G, Fong M, Kenney J, and Jacob C: Evidence for the involvement of interleukin 6 in experimental cancer cachexia. J Clin Invest 89, 1681–1684, 1992.
   PubMed Web of Science ®Google Scholar
• Tanaka Y, Eda H, Tanaka T, Udagawa T, Ishikawa T, et al.: Experimental cancer cachexia induced by transplantable colon 26 adenocarcinoma in mice. Cancer Res 50, 2290–229, 1990.
   PubMed Web of Science ®Google Scholar
• Beaulieu J, Dupont C, and Lemieux P: Whey proteins and peptides: beneficial effects on immune health. Therapy 3, 69–78, 2006.
   Google Scholar
• Nakamura K and Yamaji T: Immune-modulating effects of whey proteins and peptides. In: Whey: Types, Composition and Health Implications, Benitez RM and Ortero GM (eds.). New York, NY: Nova, 2012, pp. 137–152.
   Google Scholar
• Yamaji T and Kume H: Hepatoprotective effects of whey protein and whey peptides on hepatitis. Milk Sci 56, 115–118, 2008.
   Google Scholar
• Oz H, Chen T, and Neuman M: Nutrition intervention: a strategy against systemic inflammatory syndrome. JPEN J Parenter Enteral Nutr 33, 380–389, 2009.
   PubMed Web of Science ®Google Scholar
• Colomer R, Moreno-Nogueira J, García-Luna P, García-Peris P, García-de-Lorenzo A, et al.: N-3 fatty acids, cancer and cachexia: a systematic review of the literature. Br J Nutr 97, 823–831, 2007.
   PubMed Web of Science ®Google Scholar
• Argilés J, Busquets S, and López-Soriano F: Anti-inflammatory therapies in cancer cachexia. Eur J Pharmacol 668(Suppl. 1), S81–S86, 2011.
   PubMed Web of Science ®Google Scholar
• Fearon KCH, von Meyenfeldt MF, Moses AGW, van Geenen R, Roy A, et al.: Effect of a protein and energy dense n-3 fatty acid enriched oral supplement on loss of weight and lean tissue in cancer cachexia: a randomized double blind trial. Gut 52, 1479–1486, 2003.
   PubMed Web of Science ®Google Scholar
• Heyland D, Dhaliwal R, Suchner U, and Berger M: Antioxidant nutrients: a systematic review of trace elements and vitamins in the critically ill patient. Intensive Care Med 31, 327–337, 2005.
   PubMed Web of Science ®Google Scholar
• Nukatsuka M, Fujioka A, Saito H, Uchida J, Takeda S, et al.: Prolongation of survival and antitumor activity of antitumor drugs in murine cancer cachexia model. Jpn J Cancer Chemother 23, 887–892, 1996.
   PubMedGoogle Scholar
• Tanaka Y, Tanaka T, and Ishitsuka H: Antitumor activity of indomethacin in mice bearing advanced colon 26 carcinoma compared with those with early transplants. Cancer Res 49, 5935–5939, 1989.
   PubMed Web of Science ®Google Scholar
• Achiwa H, Yatabe Y, Hida T, Kuroishi T, Kozaki K, et al.: Prognostic significance of elevated cyclooxygenase 2 expression in primary, resected lung adenocarcinomas. Clin Cancer Res 5, 1001–1005, 1999.
   PubMed Web of Science ®Google Scholar
• Swami S, Krishnan AV, Moreno J, Bhattacharyya RB, Peehl DM, et al.: Calcitriol and genistein actions to inhibit the prostaglandin pathway: potential combination therapy to treat prostate cancer. J Nutr 137, 205S–210S, 2007.
   PubMed Web of Science ®Google Scholar
• Ranger GS, Thomas V, Jewell A, and Mokbel K.: Elevated cyclooxygenase-2 expression correlates with distant metastases in breast cancer. Anticancer Res 24, 2349–2351, 2004.
   PubMed Web of Science ®Google Scholar
• Trappe TA, Carroll CC, Dickinson JM, LeMoine JK, Haus JM, et al.: Influence of acetaminophen and ibuprofen on skeletal muscle adaptations to resistance exercise in older adults. Am J Physiol Regul Integr Comp Physiol 300, R655–R662, 2011.
   PubMed Web of Science ®Google Scholar
• Trappe TA, Standley RA, Jemiolo B, Carroll CC, and Trappe SW.: Prostaglandin and myokine involvement in the cyclooxygenase-inhibiting drug enhancement of skeletal muscle adaptations to resistance exercise in older adults. Am J Physiol Regul Integr Comp Physiol 304, R198–R205, 2013.
   PubMed Web of Science ®Google Scholar
• Lorite MJ, Cariuk P, and Tisdale MJ.: Induction of muscle protein degradation by a tumour factor. Br J Cancer 76, 1035–1040, 1997.
   PubMed Web of Science ®Google Scholar
• Smith KL and Tisdale MJ.: Mechanism of muscle protein degradation in cancer cachexia. Br J Cancer 68, 314–318, 1993.
   PubMed Web of Science ®Google Scholar
• Lai V, George J, Richey L, Kim HJ, Cannon T, et al.: Results of a pilot study of the effects of celecoxib on cancer cachexia in patients with cancer of the head, neck, and gastrointestinal tract. Head & Neck 30, 67–74, 2008.
   PubMed Web of Science ®Google Scholar
• McMillan DC, Wigmore SJ, Fearon KC, O'Gorman P, Wright CE, McArdle CS.: A prospective randomized study of megestrol acetate and ibuprofen in gastrointestinal cancer patients with weight loss. Br J Cancer 79, 495–500, 1999.
   PubMed Web of Science ®Google Scholar
• Carson JA and Baltgalvis KA: Interleukin 6 as a key regulator of muscle mass during cachexia. Exerc Sport Sci Rev 38, 168–176, 2010.
   PubMed Web of Science ®Google Scholar
• Kemik O, Sumer A, Kemik AS, Hasirci I, Purisa S, et al.: The relationship among acute-phase response proteins, cytokines and hormones in cachectic patients with colon cancer. World J Surg Oncol 8, 85, 2010.
   Web of Science ®Google Scholar
• Watanabe T, Shibata M, Nishiyama H, Soeda S, Furukawa S, et al.: Serum levels of rapid turnover proteins are decreased and related to systemic inflammation in patients with ovarian cancer. Oncol Lett 7, 373–377, 2014.
   PubMed Web of Science ®Google Scholar
• Glass DJ: Signaling pathways perturbing muscle mass. Curr Opin Clin Nutr Metab Care 13, 225–229, 2010.
   PubMed Web of Science ®Google Scholar
• Cariuk P, Lorite MJ, Todorov PT, Field WN, Wigmore SJ, et al.: Induction of cachexia in mice by a product isolated from the urine of cachectic cancer patients. Br J Cancer 76, 606–613, 1997.
   PubMed Web of Science ®Google Scholar
• Wyke S, Russell S, and Tisdale M: Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activation. Br J Cancer 91, 1742–1750, 2004.
   PubMed Web of Science ®Google Scholar
• Eley H, Russell S, and Tisdale M: Effect of branched-chain amino acids on muscle atrophy in cancer cachexia. Biochem J 407, 113–120, 2007.
   PubMed Web of Science ®Google Scholar
• Ravasco P, Monteiro-Grillo I, Vidal P, and Camilo M: Cancer: disease and nutrition are key determinants of patients' quality of life. Support Care Cancer 12, 246–252, 2004.
   PubMed Web of Science ®Google Scholar