REFERENCES
- Siegal R, DeSantis C, Virgo K, Stein K, Mariotto A, et al.: Cancer treatment and survivorship statistics, 2012. CA Cancer J. Clin 62, 220–241, 2012.
- Badger TM, Ronis MJJ, Simmen R, and Simmen F: Soy protein isolate and protection against cancer. J Am Coll Nutr 24, 146S–149S, 2005.
- Bounous G, Batist G, and Gold P: Whey proteins in cancer prevention. Cancer Lett 57, 91–94, 1991.
- Pepe G, Tenore GC, Mastrocinque R, Stusio P, and Campiglia P: Potential anticarcinogenic peptides from bovine milk. J Amino Acids e:939804, 2013.
- Chatterton DEW, Smithers G, Roupas P, and Brodkorb A: Bioactivity of b-lactalbumin and a-lactalbumin: technological implications for processing. Int Dairy J 16, 1229–1240, 2006.
- Svensson M, Fast J, Mossberg AK, Duringer C, Gustafsson L, et al.: Alpha-lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells). Protein Sci 12, 2794–2804, 2003.
- Laursen I, Briand P, and Lakkesfeldt AE: Serum albumin as a modulator of growth of a human breast cancer cell line, MCF-7. Anticancer Res 10, 343–351, 1990.
- Zagulski T, Lipinski P, Zagulska A, Broniek S, and Jarzbeck Z: Lactoferrin can protect mice against a lethal dose of E. coli in experimental infection in vivo. Br J Exp Pathol 70, 697–704, 1989.
- Hatzoglou A, Bakogeorgou E, Hatzoglou C, Martin PM, and Castanas E: Antiproliferative and receptor binding properties of alpha and beta casmorphins in the T47D human breast cancer cell line. Eur J Pharmacol 310, 217–223, 1996.
- Kampa M, Loukas S, Hatzoglou A, Martin P, Martin PM, et al.: Identification of a novel opioid peptide (Tyr-Val-Pro-Phe-Pro) derived from human as1-casein (as1-casomorphin, and as1-casomorphin amide). Biochem J 319, 903–908, 1996.
- Perego S, Cosentino S, Fiorilli A, Tettamanti G, and Ferraretto A: Casein phosphopeptides modulate proliferation and apoptosis in HT-29 cell line through their interaction with voltage-operated-L-type calcium channels. J Nutr Biochem 23, 808–816, 2012.
- Eliasson LT, Berge G, Sveinbjornsson B, Svendsen JS, Vorland LH, et al.: Evidence for direct antitumor mechanism of action of bovine lactoferricin. Anticancer Res 22, 2703–2710, 2002.
- Mader JS, Salsman J, Conrad DM, and Hoskin DW: Bovine lactoferricin selectively induces apoptosis in human leukemia and carcinoma cell lines. Mol Cancer Ther 4, 612–624, 2005.
- Eliasson LT, Berge G, Leknessund A, Wikman M, Lindin I, et al.: The antimicrobial peptide lactoferricin B, is cytotoxic to neuroblastoma cells in vitro and inhibits xenograft growth in vivo. Int J Cancer 119, 493–500, 2006.
- Hakkak R, Korourian S, Shelnutt S, Lensing S, Ronis MJJ, et al.: Diets containing whey proteins or soy protein isolate protect against 7,12-Dimethylbenz(a)anthracene-induced mammary tumors in female rats. Cancer Epidemiol. Biomarkers Prev 9, 113–117, 2000.
- Eason RR, Velarde MC, Chatman L, Till SR, Geng Y, et al.: Dietary exposure to whey proteins alters rat mammary gland proliferation, apoptosis, and gene expression during postnatal development. J. Nutr 134, 3370–3377, 2004.
- Dave B, Eason RR, Geng Y, Su Y, Badger TM, et al.: Tp53-associated growth arrest and DNA damage repair gene expression is attenuated in mammary epithelial cells of rats fed whey proteins. J Nutr 136, 1156–1160, 2006.
- Eason RR, Till SR, Frank JA, Badger TM, Korourian S, et al.: Tumor-protective and tumor-promoting actions of dietary whey proteins in an N-methyl-N-nitrosourea model of rat mammary carcinogenesis. Nutr Cancer 55, 171–177, 2006.
- Xiao R, Carter JA, Linz AL, Ferguson M, Badger TM, et al.: Dietary whey protein lowers serum C-peptide concentration and duodenal SREBP-1c mRNA abundance and reduces occurrence of duodenal tumors and colon aberrant crypt foci in azoxymethane-treated male rats. J Nutr Biochem 17, 626–634, 2006.
- Reeves PG, Nielsen FH, and Fahey GC, Jr.: AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 123, 1939–1951, 1993.
- Ronis MJ, Rowlands JC, Hakkak R, and Badger TM: Inducibility of hepatic CYP1A enzymes by 3-methylcholanthrene and isosafrole differs in male rats fed diets containing casein, soy protein isolate or whey from conception to adulthood. J Nutr 131, 1180–1188, 2001.
- Milliken GA and Johnson DE: Analysis of Messy Data. New York, NY: Chapman & Hall, 1992.
- Fisher L and Van Belle G: Biostatistics: A Methodology for the Health Sciences. New York, NY: Wiley, 1993.
- Lee ET: Statistical Methods for Survival Data Analysis. New York, NY: Wiley, 1992.
- Zeger SL and Liang KY: Longitudinal data analysis for discrete and continuous outcomes. Biometrics 42, 121–130, 1986.
- Hakkak R, Korourian S, Ronis MJJ, Johnston J, and Badger TM: Lifetime whey protein consumption protects against azoxymethane-induced colon tumors in male rats. Cancer Epidemiology Biomarkers and Prevention 10, 555–558, 2001.
- Rowlands RC, He L, Hakkak R, Ronis MJJ, and Badger TM: Soy and whey proteins downregulate DMBA-induced liver and mammary gland CYP1 expression in female rats. J Nutr 131, 3281–3287, 2001.