References
- Genkinger JM, Platz EA, Hoffman SC, Comstock GW, and Helzlsouer KJ: Fruit, vegetable, and antioxidant intake and all-cause, cancer, and cardiovascular disease mortality in a community-dwelling population in Washington County, Maryland. Am J Epidemiol 160, 1223–1233, 2004.
- Rieck G and Fiander A: The effect of lifestyle factors on gynaecological cancer. Best Pract Res Clin Obstet Gynaecol 20, 227–251, 2006.
- Trottier G, Bostrom PJ, Lawrentschuk N, and Fleshner NE: Nutraceuticals and prostate cancer prevention: a current review. Nat Rev Urol 7, 21–30, 2010.
- Pan SY, Ugnat AM, Mao Y, Wen SW, and Johnson KC: A case-control study of diet and the risk of ovarian cancer. Cancer Epidemiol Biomark Prevent 13, 1521–1527, 2004.
- Pan SY, Zhou J, Gibbons L, Morrison H, and Wen SW: Antioxidants and breast cancer risk - a population-based case-control study in Canada. BMC Cancer 11, 372, 2011.
- Khan N, Afaq F, and Mukhtar H: Cancer chemoprevention through dietary antioxidants: progress and promise. Antioxid Redox Sign 10, 475–510, 2008.
- Kalra EK: Nutraceutical–definition and introduction. AAPS Pharm Sci 5, E25, 2003.
- Brower V: Nutraceuticals: poised for a healthy slice of the healthcare market? Nat Biotechnol 16, 728–731, 1998.
- Holzapfel NP, Holzapfel BM, Champ S, Feldthusen J, Clements J, et al.: The potential role of lycopene for the prevention and therapy of prostate cancer: from molecular mechanisms to clinical evidence. Int J Mol Sci 14, 14620–14646, 2013.
- American Institute for Cancer Research, AICR: Available at http://www.aicr.org/foods-that-fight-cancer/foodsthatfightcancer_tomatoes.html, 2015.
- Mobus V, Gerharz CD, Press U, Moll R, Beck T, et al.: Morphological, immunohistochemical and biochemical-characterization of 6 newly established human ovarian-carcinoma cell-lines. Int J Cancer 52, 76–84, 1992.
- Quent VM, Loessner D, Friis T, Reichert JC, and Hutmacher DW: Discrepancies between metabolic activity and DNA content as tool to assess cell proliferation in cancer research. J Cell Mol Med 14, 1003–1013, 2010.
- Schuurman W, Levett PA, Pot MW, van Weeren PR, Dhert WJ, et al.: Gelatin-methacrylamide hydrogels as potential biomaterials for fabrication of tissue-engineered cartilage constructs. Macromol Biosci 13, 551–561, 2013.
- Van Den Bulcke AI, Bogdanov B, De Rooze N, Schacht EH, Cornelissen M, et al.: Structural and rheological properties of methacrylamide modified gelatin hydrogels. Biomacromolecules 1, 31–38, 2000.
- Kaemmerer E, Melchels FP, Holzapfel BM, Meckel T, Hutmacher DW, et al.: Gelatine methacrylamide-based hydrogels: An alternative three-dimensional cancer cell culture system. Acta Biomater 10, 2551–2562, 2014.
- Loessner D, Stok KS, Lutolf MP, Hutmacher DW, Clements JA, et al.: Bioengineered 3D platform to explore cell-ECM interactions and drug resistance of epithelial ovarian cancer cells. Biomaterials 31, 8494–8506, 2010.
- Allen CM, Schwartz SJ, Craft NE, Giovannucci EL, De Groff VL, et al.: Changes in plasma and oral mucosal lycopene isomer concentrations in healthy adults consuming standard servings of processed tomato products. Nutr Cancer 47, 48–56, 2003.
- Mayne ST, Handelman GJ, and Beecher G: Beta-Carotene and lung cancer promotion in heavy smokers–a plausible relationship? J Natl Cancer Inst 88, 1513–1515, 1996.
- Lengyel E: Ovarian cancer development and metastasis. Am J Pathol 177, 1053–1064, 2010.
- Lindshield BL, Canene-Adams K, and Erdman JW, Jr.: Lycopenoids: are lycopene metabolites bioactive? Arch Biochem Biophys 458, 136–140, 2007.
- Mein JR, Lian F, and Wang XD: Biological activity of lycopene metabolites: implications for cancer prevention. Nutr Rev 66, 667–683, 2008.
- Ford NA, Elsen AC, Zuniga K, Lindshield BL, and Erdman JW, Jr.: Lycopene and apo-12′-lycopenal reduce cell proliferation and alter cell cycle progression in human prostate cancer cells. Nutr Cancer 63, 256–263, 2011.
- Hantz HL, Young LF, and Martin KR: Physiologically attainable concentrations of lycopene induce mitochondrial apoptosis in LNCaP human prostate cancer cells. Exp Biol Med 230, 171–179, 2005.
- Czeczuga-Semeniuk E, Bielawski T, Lemancewicz D, Rusak M, and Wolczynski S: Vitamin A family compounds, estradiol, and docetaxel in proliferation, apoptosis and immunocytochemical profile of human ovary endometrioid cancer cell line CRL-11731. Folia Histochem Cytobiol 47, S127–135, 2009.
- Kanagaraj P, Vijayababu MR, Ravisankar B, Anbalagan J, Aruldhas MM, et al.: Effect of lycopene on insulin-like growth factor-I, IGF binding protein-3 and IGF type-I receptor in prostate cancer cells. J Cancer Res Clin Oncol 133, 351–359, 2007.
- Park YO, Hwang ES, and Moon TW: The effect of lycopene on cell growth and oxidative DNA damage of Hep3B human hepatoma cells. Biofactors 23, 129–139, 2005.
- Zhang X, Wang Q, Neil B, and Chen X: Effect of lycopene on androgen receptor and prostate-specific antigen velocity. Chinese Med J 123, 2231–2236, 2010.
- Fornelli F, Leone A, Verdesca I, Minervini F, and Zacheo G: The influence of lycopene on the proliferation of human breast cell line (MCF-7). Toxicol In Vitro 21, 217–223, 2007.
- Rafi MM, Kanakasabai S, Reyes MD, and Bright JJ: Lycopene modulates growth and survival associated genes in prostate cancer. J Nutr Biochem 24, 1724–1734, 2013.
- Teodoro AJ, Oliveira FL, Martins NB, Maia Gde A, Martucci RB, et al.: Effect of lycopene on cell viability and cell cycle progression in human cancer cell lines. Cancer Cell Int 12, 36, 2012.
- Uppala PT, Dissmore T, Lau BH, Andacht T, and Rajaram S: Selective inhibition of cell proliferation by lycopene in MCF-7 breast cancer cells in vitro: a proteomic analysis. Phytother Res 27, 595–601, 2013.
- Kotake-Nara E, Kushiro M, Zhang H, Sugawara T, Miyashita K, et al.: Carotenoids affect proliferation of human prostate cancer cells. J Nutr 131, 3303–6, 2001.
- Yang CM, Lu IH, Chen HY, and Hu ML: Lycopene inhibits the proliferation of androgen-dependent human prostate tumor cells through activation of PPARgamma-LXRalpha-ABCA1 pathway. J Nutr Biochem. 23, 8–17, 2012.
- Hwang ES and Bowen PE: Effects of tomato paste extracts on cell proliferation, cell-cycle arrest and apoptosis in LNCaP human prostate cancer cells. Biofactors 23, 757–84, 2005.
- Prakash P, Russell RM, and Krinsky NI: In vitro inhibition of proliferation of estrogen-dependent and estrogen-independent human breast cancer cells treated with carotenoids or retinoids. J Nutr 131, 1574–80, 2001.
- Huang CS, Fan YE, Lin CY, and Hu ML: Lycopene inhibits matrix metalloproteinase-9 expression and down-regulates the binding activity of nuclear factor-kappa B and stimulatory protein-1. J Nutr Biochem 18, 449–56, 2007.
- Palozza P, Simone RE, Catalano A, and Mele MC: Tomato lycopene and lung cancer prevention: from experimental to human studies. Cancers. 3, 2333–57, 2011.
- Huang CS, Shih MK, Chuang CH, and Hu ML: Lycopene inhibits cell migration and invasion and upregulates Nm23-H1 in a highly invasive hepatocarcinoma, SK-Hep-1 cells. J Nutr 135, 2119–23, 2005.
- Lin MC, Wang FY, Kuo YH, and Tang FY: Cancer chemopreventive effects of lycopene: suppression of MMP-7 expression and cell invasion in human colon cancer cells. J Agric Food Chem 59, 11304–18, 2011.
- Bureyko T, Hurdle H, Metcalfe JB, Clandinin MT, and Mazurak VC: Reduced growth and integrin expression of prostate cells cultured with lycopene, vitamin E and fish oil in vitro. Br J Nutr 101, 990–7, 2009.
- Burdett E, Kasper FK, Mikos AG, and Ludwig JA: Engineering tumors: a tissue engineering perspective in cancer biology. Tissue Eng Part B Rev 16, 351–9, 2010.
- Sterling JA, Edwards JR, Martin TJ, and Mundy GR: Advances in the biology of bone metastasis: how the skeleton affects tumor behavior. Bone 48, 6–15, 2011.
- Czeczuga-Semeniuk E, Lemancewicz D, and Wolczynski S: Can vitamin A modify the activity of docetaxel in MCF-7 breast cancer cells? Folia Histochem Cytobiol 45 (Suppl 1), S169-74, 2007.
- Tang Y, Parmakhtiar B, Simoneau AR, Xie J, Fruehauf J, et al.: Lycopene enhances docetaxel's effect in castration-resistant prostate cancer associated with insulin-like growth factor I receptor levels. Neoplasia 13, 108–19, 2011.
- Lawenda BD, Kelly KM, Ladas EJ, Sagar SM, Vickers A, et al.: Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy? Natl Cancer Inst 100, 773–83, 2008.
- Noguchi S: Predictive factors for response to docetaxel in human breast cancers. Cancer Sci 97, 813–20, 2006.