Bioassay-Guided Fractionation and In Vitro Antiproliferative Effects of Fractions of Artemisia nilagirica on THP-1 cell line

References

• Farnsworth NR, Akerele O, Bingel AS, Soejarto DD, and Guo Z: Medicinal plants in therapy. Bull World Health Organ 63, 965–981, 1985.
   PubMed Web of Science ®Google Scholar
• Cragg GM, Newman DJ, and Snader KM: Natural products in drug discovery and development. J Nat Prod 60, 52–60, 1997.
   PubMed Web of Science ®Google Scholar
• Reddy L, Odhav B, and Bhoola KD: Natural products for cancer prevention: a global perspective. Pharmacol Ther 99, 1–13, 2003.
   PubMed Web of Science ®Google Scholar
• Cragg GM and Newman DJ: Plants as a source of anticancer agents. J Ethnopharmacol 100, 72–79, 2005.
   PubMed Web of Science ®Google Scholar
• Tan G, Gyllenhaal C, and Soejarto DD: Biodiversity as a source of anticancer drugs. Curr Drug Targets 7, 265–277, 2006.
   PubMed Web of Science ®Google Scholar
• Mehta RG, Murillo G, Naithani R, and Peng X: Cancer chemoprevention by natural products: how far have we come? Pharm Res 27, 950–961, 2010.
   PubMed Web of Science ®Google Scholar
• Desai AG, Qazi GN, Ganju RK, El-Tamer M, Singh J, et al.: Medicinal plants and cancer chemoprevention. Curr Drug Metab 9, 581–591, 2008.
   PubMed Web of Science ®Google Scholar
• Guilford JM and Pezzuto JM: Natural products as inhibitors of carcinogenesis. Expert Opin Investig Drugs 17, 1341–1352, 2008.
   PubMed Web of Science ®Google Scholar
• Kluck RM, Bossy-Wetzel E, Green DR, and Newmeyer DD: The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275(5303), 1132–1136, 1997.
   PubMed Web of Science ®Google Scholar
• Newman DJ, Cragg GM, and Snader KM: Natural products as sources of new drugs over the period 1981–2002. J Nat Prod 66, 1022–1037, 2003.
   PubMed Web of Science ®Google Scholar
• Cragg GM, Kingston DGI, and Newman DJ: Anticancer Agents from Natural Products. Boca Raton, FL: CRC Press, Taylor & Francis Group, 2005.
   Google Scholar
• Da Rocha BA, Lopes RM, and Schwartsmann G: Natural products in anticancer therapy. Curr Opin Pharmacol 1, 364–369, 2001.
   PubMedGoogle Scholar
• Newman DJ and Cragg GM: Natural products as sources of new drugs over the last 25 years. J Nat Prod 70, 461–477, 2007.
   PubMed Web of Science ®Google Scholar
• Butler MS: Natural products to drugs: natural product-derived compounds in clinical trials. Nat Prod Rep 25, 475–516, 2008.
   PubMed Web of Science ®Google Scholar
• Seffrin JR: Cancer control as a human right. Lancet Oncol 9, 409–411, 2008.
   PubMed Web of Science ®Google Scholar
• Mousseau M, Schaerer R, Pasquier B, Chauvin C, Nissou MF, et al.: A study of the expression of four chemoresistance related genes in human primary and metastatic brain tumours. Eur J Cancer 29, 753–759, 1993.
   Web of Science ®Google Scholar
• Scheck AC, Perry K, Hank NC, and Clark WD: Anticancer activity of extracts derived from the mature roots of Scutellaria baicalensis on human malignant brain tumor cells. BMC Complement Altern Med 6, 27, 2006.
   PubMedGoogle Scholar
• Walker MC, Masters JR, Parris CN, Hepburn PJ, and English PJ: Intravesical chemotherapy: in vitro studies on the relationship between dose and cytotoxicity. Urol Res 14, 137–140, 1986.
   PubMedGoogle Scholar
• Shibata MA, Hasegawa R, Kurata Y, Yamada M, Tamano S, et al.: Bladder epithelial hyperplasia in F344 rats after intravesical instillation of the antitumor chemotherapeutic agents Adriamycin® and Mitomycin C. Cancer Lett 49, 41–49, 1990.
   PubMed Web of Science ®Google Scholar
• Huncharek M, Mcgarry R, and Kupelnick B: Impact of intravesical chemotherapy on recurrence rate of recurrent superficial transitional cell carcinoma of the bladder: results of a meta-analysis. Anticancer Res 21(1B), 765–769, 2001.
   PubMed Web of Science ®Google Scholar
• Soobrattee MA, Bahorun T, and Aruoma OI: Chemopreventive actions of polyphenolic compounds in cancer. Biofactors 27, 19–35, 2006.
   PubMed Web of Science ®Google Scholar
• Chopra RN, Chopra IC, Handa KL, and Kapoor LD: Indigenous Drug of India. 2nd Edition. Calcutta: Academic publication, 1994.
   Google Scholar
• Lewis WH and Elvin-Lewis MPF: Medical botany: plants affecting human health. J Wiley, 2003.
   Google Scholar
• Gul MZ, Bhakshu LM, Ahmad F, Kondapi AK, Qureshi IA, et al.: Evaluation of Abelmoschus moschatus extracts for antioxidant, free radical scavenging, antimicrobial and antiproliferative activities using in vitro assays. BMC Complement Altern Med 11, 64, 2011.
   PubMed Web of Science ®Google Scholar
• Gul MZ, Ahmad F, Kondapi AK, Qureshi IA, and Ghazi IA: Antioxidant and antiproliferative activities of Abrus precatorius leaf extracts - an in vitro study. BMC Complement Altern Med 13, 53, 2013.
   PubMed Web of Science ®Google Scholar
• Bhattacharjee S, Gupta G, Bhattacharya P, Mukherjee A, Mujumdar SB, et al.: Quassin alters the immunological patterns of murine macrophages through generation of nitric oxide to exert antileishmanial activity. J Antimicrob Chemother 63(2), 317–324, 2009.
   PubMed Web of Science ®Google Scholar
• Tokarska-Schlattner M, Wallimann T, and Schlattner U: Alterations in myocardial energy metabolism induced by the anticancer drug doxorubicin. C R Biol 329, 657–668, 2006.
   PubMed Web of Science ®Google Scholar
• Kalinina TS, Bannova AV, and Dygalo NN: Quantitative evaluation of DNA fragmentation. Bull Exp Biol Med 34, 554–556, 2002.
   Web of Science ®Google Scholar
• Ait-Mohamed O, Battisti V, Joliot V, Fritsch L, Pontis J, et al.: Acetonic extract of Buxus sempervirens induces cell cycle arrest, apoptosis and autophagy in breast cancer cells. PLoS One 6(9), 24537, 2011.
   Web of Science ®Google Scholar
• Horai H, Arita M, Kanaya S, Nihei Y, Ikeda T, et al.: MassBank: A public repository for sharing mass spectral data for life sciences. J Mass Spectrom 45(7), 703–714, 2010.
   PubMed Web of Science ®Google Scholar
• Goodman M, Bostick RM, Kucuk O, and Jones DP: Clinical trials of antioxidants as cancer prevention agents: past, present, and future. Free Radic Biol Med 51(5), 1068–1084, 2011.
   PubMed Web of Science ®Google Scholar
• Bunz F: Cell death and cancer therapy. Curr Opin Pharmacol 1, 337–341, 2001.
   PubMedGoogle Scholar
• Reed JC and Pellecchia M: Apoptosis-based therapies for hematologic malignancies. Blood 106, 408–418, 2005.
   PubMed Web of Science ®Google Scholar
• Taraphdar AK, Roy M, and Bhattacharya RK: Natural products as inducers of apoptosis: implication for cancer therapy and prevention. Curr Sci 80, 1387–1396, 2001.
   Web of Science ®Google Scholar
• Aggarwal BB, Ichikawa H, Garodia P, Weerasinghe P, Sethi G, et al.: From traditional Ayurvedic medicine to modern medicine: identification of therapeutic targets for suppression of inflammation and cancer. Exp Opin Ther Targets 10, 87–118, 2006.
   PubMed Web of Science ®Google Scholar
• Suffness M and Pezzuto JM: Assays related to cancer drug discovery, In: Methods in Plant Biochemistry: Assays for Bioactivity, Hostettmann K (Ed.). London: Academic Press, 1990, pp. 71–133.
   Google Scholar
• Pulido R, Bravo L, and Saura-Calixto F: Antioxidant activity of dietary polyphenols as determined by a modified ferric reducing/antioxidant power assay. J Agr Food Chem 48, 3396–3402, 2000.
   PubMed Web of Science ®Google Scholar
• Saraste A and Pulkki K: Morphologic and biochemical hallmarks of apoptosis. Cardiovasc Res 45, 528–537, 2000.
   PubMed Web of Science ®Google Scholar
• Elmore S: Apoptosis: A review of programmed cell death. Toxicol Pathol 35, 495–516, 2007.
   PubMed Web of Science ®Google Scholar
• Hu H, Kang J, Chen R, Mamuti W, Wu G, and Yuan W: Drug-induced apoptosis of Echinococcus granulosus protoscoleces. Parasitol Res 109, 453–459, 2007.
   Web of Science ®Google Scholar
• Cohn SM, Sun XM, Snowden RT, Dinsdale D, and Skillter DN: Morphological features of apoptosis may occur in the absences of micronucleosomal DNA fragmentation. Biochem J 286, 331–334, 1992.
   PubMed Web of Science ®Google Scholar
• Ravi A, Mallika A, Sama V, Begum AS, Khan RS, et al.: Antiproliferative activity and standardization of Tecomella undulate bark extract on K562 cells. J Ethnopharmacol 137, 1353–1359, 2011.
   PubMed Web of Science ®Google Scholar
• Singh RP, Dhanalakshmi S, and Agarwal R: Phytochemicals as cell cycle modulators. Cell Cycle 1(3), 156–161, 2002.
   PubMed Web of Science ®Google Scholar
• Vermes I, Haanen C, Steffens-Nakken H, and Reutelingsperger C: A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Methods 184(1), 39–51, 1995.
   PubMed Web of Science ®Google Scholar
• Nicholson DW and Thornberry NA: Caspases: killer proteases. Trends Biochem Sci 22, 299–306, 1997.
   PubMed Web of Science ®Google Scholar
• Woo HJ, Jun do Y, Lee JY, Woo MH, Yang CH, et al.: Apoptogenic activity of 2alpha,3alpha-dihydroxyurs-12-ene-28-oic acid from Prunella vulgaris var. lilacina is mediated via mitochondria-dependent activation of caspase cascade regulated by Bcl-2 in human acute leukemia Jurkat T cells. J Ethnopharmacol 135, 626–635, 2011.
   PubMed Web of Science ®Google Scholar
• Looi CY, Arya A, Cheah FK, Muharram B, Leong KH, et al.: Induction of apoptosis in human breast cancer cells via caspase pathway by vernodalin isolated from Centratherum anthelminticum (L.) seeds. PLoS One 8(2), e56643, 2013.
   PubMed Web of Science ®Google Scholar
• Deigner HP and Kinscherf R: Modulating apoptosis: current applications and prospects for future drug development. Curr Med Chem 6, 399–414, 1999.
   PubMed Web of Science ®Google Scholar
• Lee MS and Kerns EH: LC/MS applications in drug development. Mass Spectrom Rev 18(3–4), 187–279, 1999. 2012.
   Web of Science ®Google Scholar
• He ZZ, Yan JF, Song ZJ, Ye F, Liao X, et al.: Chemical constituents from the aerial parts of Artemisia minor. J Nat Prod 72(6), 1198–1201, 2009.
   PubMed Web of Science ®Google Scholar
• Hsieh YJ, Chang CJ, Wan CF, Chen CP, Chiu YH, et al.: Euphorbia formosana root extract induces apoptosis by caspase-dependent cell death via Fas and mitochondrial pathway in THP-1 human leukemic cells. Molecules 18(2), 1949–1962, 2013.
   PubMed Web of Science ®Google Scholar
• Farah A, Monteiro M, Donangelo CM, and Lafay S: Chlorogenic acids from green coffee extract are highly bioavailable in humans. J Nutr 138, 2309–2315, 2008.
   PubMed Web of Science ®Google Scholar
• Urushisaki T, Takemura T, Tazawa S, Fukuoka M, Hosokawa-Muto J, et al.: Caffeoylquinic acids are major constituents with potent anti-influenza effects in Brazilian green propolis water extract. Evid Based Complement Alternat Med 2011, 254914, 2011.
   PubMed Web of Science ®Google Scholar
• Wang D, Xiang DB, He YJ, Li ZP, Wu XH et al.: Effect of caffeic acid phenethyl ester on proliferation and apoptosis of colorectal cancer cells in vitro. World J Gastroenterol 11(26), 4008–4012, 2005.
   PubMed Web of Science ®Google Scholar
• Li WX, Cui CB, Cai B, Wang HY, and Yao XS: Flavonoids from Vitex trifolia L. inhibit cell cycle progression at G2/M phase and induce apoptosis in mammalian cancer cells. J Asian Nat Prod Res 7(4), 615–626, 2005.
   PubMed Web of Science ®Google Scholar
• Liu E, Kuang Y, He W, Xing X, and Gu J: Casticin induces human glioma cell death through apoptosis and mitotic arrest. Cell Physiol Biochem 31, 805–814, 2013.
   PubMed Web of Science ®Google Scholar
• Chen AY and Chen YC: A review of the dietary flavonoid, kaempferol on human health and cancer chemoprevention. Food Chem 138, 2099–2107, 2013.
   PubMed Web of Science ®Google Scholar
• Kadifkova PT, Kulevanova S, and Stefova M: In vitro antioxidant activity of some Teucrium species (Lamiaceae). Acta Pharm 55, 207–214, 2005.
   PubMedGoogle Scholar
• Meirinhos J, Silva BM, Valentão P, Seabra RM, Pereira JA, et al.: Analysis and quantification of flavonoidic compounds from Portuguese olive (Olea europaea L.) leaf cultivars. Nat Prod Res 9(2), 189–195, 2005.
   Google Scholar
• Androutsopoulos VP, Mahale S, Arroo RR, and Potter G: Anticancer effects of the flavonoid diosmetin on cell cycle progression and proliferation of MDA-MB 468 breast cancer cells due to CYP1 activation. Oncol Rep 21, 1525–1528, 2009.
   PubMed Web of Science ®Google Scholar
• Caltagirone S, Rossi C, Poggi A, Ranelletti FO, Natali PG, et al.: Flavonoids apigenin and quercetin inhibit melanoma growth and metastatic potential. Int J Cancer 87, 595–600, 2000.
   PubMed Web of Science ®Google Scholar
• Martens SM, Marta RA, Martens JK, and McMahon TB: Consecutive fragmentation mechanisms of protonated ferulic acid probed by Infrared multiple photon dissociation spectroscopy and electronic structure calculations. J Am Soc Mass Spectrom 23(10), 1697–1706, 2012.
   PubMed Web of Science ®Google Scholar
• Clifford MN, Johnston KL, Knight S, and Kuhnert N: Hierarchical scheme for LC-MSn identification of chlorogenic acids. J Agric Food Chem 51(10), 2900–2911, 2003.
   PubMed Web of Science ®Google Scholar
• Kupchan SM, Sigel CW, Knox JR, and Udayamurthy MS: Tumor inhibitors. XXXVI. Eupatin and eupatoretin, two cytotoxic flavonols from Eupatorium semiserratum. J Org Chem 34(5), 1460–1463, 1969.
   Web of Science ®Google Scholar
• Turi CE, Shipley PR, and Murch SJ: North American Artemisia species from the subgenus Tridentatae (Sagebrush): a phytochemical, botanical and pharmacological review. Phytochem 98, 9–26, 2014.
   PubMed Web of Science ®Google Scholar
• Romo J, Romo de Vivar A, Treviño R, Joseph-Nathan P, and Díaz E: Constituents of Artemisia and chrysanthemum species-the structures of chrysartemins A and B. Phytochem 9(7), 1615–1621, 1970.
   Web of Science ®Google Scholar
• Moharram FA, Marzouk MS, El-Shenawy SM, Gaara AH, and El Kady WM: Polyphenolic profile and biological activity of Salvia splendens leaves. J Pharm Pharmacol 64(11), 1678–1687, 2012.
   PubMed Web of Science ®Google Scholar