1α,25-Dihydroxyvitamin D Inhibits the Metastatic Capability of MCF10CA1a and MDA-MB-231 Cells in an In Vitro Model of Breast to Bone Metastasis

References

• Cancer of the Breast: SEER Stat Fact Sheets. Bethesda, MD: National Cancer Institute. 2014.
   Google Scholar
• Lu J, Steeg PS, Price JE, Krishnamurthy S, Mani SA, et al.: Breast cancer metastasis: challenges and opportunities. Cancer Res 69, 4951–4953, 2009.
   PubMedGoogle Scholar
• Gupta GP and Massagué J: Cancer metastasis: building a framework. Cell 127, 679–695, 2006.
   PubMed Web of Science ®Google Scholar
• Patel LR, Camacho DF, Shiozawa Y, Pienta KJ, and Taichman RS: Mechanisms of cancer cell metastasis to the bone: a multistep process. Future Oncol 7, 1285–1297, 2011.
   PubMed Web of Science ®Google Scholar
• Schmidt-Kittler O, Ragg T, Daskalakis A, Granzow M, Ahr A, et al.: From latent disseminated cells to overt metastasis: genetic analysis of systemic breast cancer progression. Proc Natl Acad Sci U S A 100, 7737–7742, 2003.
   PubMed Web of Science ®Google Scholar
• Foroni C, Broggini M, Generali D, and Damia G: Epithelial-mesenchymal transition and breast cancer: role, molecular mechanisms and clinical impact. Cancer Treat Rev 38, 689–697, 2012.
   PubMed Web of Science ®Google Scholar
• Bertone-Johnson ER, Chen WY, Holick MF, Hollis BW, Colditz GA, et al.: Plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D and risk of breast cancer. Cancer Epidemiol Biomarkers Prev 14, 1991–1997, 2005.
   PubMed Web of Science ®Google Scholar
• Chen P, Hu P, Xie D, Qin Y, Wang F, et al.: Meta-analysis of vitamin D, calcium and the prevention of breast cancer. Breast Cancer Res Treat 121, 469–477, 2010.
   PubMed Web of Science ®Google Scholar
• Mohr SB, Gorham ED, Kim J, Hofflich H, and Garland CF: Meta-analysis of vitamin D sufficiency for improving survival of patients with breast cancer. Anticancer Res 34, 1163–1166, 2014.
   PubMed Web of Science ®Google Scholar
• Rossdeutscher L, Li J, Luco AL, Fadhil I, Ochietti B, et al.: Chemoprevention activity of 25-hydroxyvitamin D in the MMTV-PyMT mouse model of breast cancer. Cancer Prev Res 8, 120–128, 2014.
   PubMed Web of Science ®Google Scholar
• Chiang KC, Yeh CN, Hsu JT, Jan YY, Chen LW, et al.: The vitamin D analog, MART-10, represses metastasis potential via downregulation of epithelial-mesenchymal transition in pancreatic cancer cells. Cancer Lett 354, 235–244, 2014.
   PubMed Web of Science ®Google Scholar
• So JY, Smolarek AK, Salerno DM, Maehr H, Uskokovic M, et al.: Targeting CD44-STAT3 signaling by Gemini vitamin D analog leads to inhibition of invasion in basal-like breast cancer. PLoS One 8, e54020, 2013.
   PubMed Web of Science ®Google Scholar
• El Abdaimi K, Dion N, Papavasiliou V, Cardinal PE, Binderup L, et al.: The vitamin D analogue EB 1089 prevents skeletal metastasis and prolongs survival time in nude mice transplanted with human breast cancer cells. Cancer Res 60, 4412–4418, 2000.
   PubMed Web of Science ®Google Scholar
• NCI: Metastatic Cancer Fact Sheet. Bethesda, MD: National Cancer Institute (NCI). 2015.
   Google Scholar
• Parikh MR, Minser KE, Rank LM, Glackin CA, and Kirshner J: A reconstructed metastasis model to recapitulate the metastatic spread in vitro. Biotechnol J 9, 1129–1139, 2014.
   PubMed Web of Science ®Google Scholar
• Santner S, Dawson P, Tait L, Soule H, Mohamed A, et al.: Malignant MCF10CA1 cell lines derived from premalignant human breast epithelial MCF10AT cells. Cancer Res Treat 65, 101–110, 2001.
   Web of Science ®Google Scholar
• Drabsch Y, He S, Zhang L, Snaar-Jagalska BE, and ten Dijke P: Transforming growth factor-β signalling controls human breast cancer metastasis in a zebrafish xenograft model. Breast Cancer Res 15, R106, 2013.
   PubMed Web of Science ®Google Scholar
• Zheng W, Tayyari F, Gowda GA, Raftery D, McLamore ES, et al.: 1,25-Dihydroxyvitamin D regulation of glucose metabolism in Harvey-ras transformed MCF10A human breast epithelial cells. J Steroid Biochem Mol Biol 138, 81–89, 2013.
   PubMed Web of Science ®Google Scholar
• Onder TT, Gupta PB, Mani SA, Yang J, Lander ES, et al.: Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Res 68, 3645–3654, 2008.
   PubMed Web of Science ®Google Scholar
• Coleman RE: Clinical features of metastatic bone disease and risk of skeletal morbidity. Clin Cancer Res 12, 6243s–6249s, 2006.
   PubMed Web of Science ®Google Scholar
• Sathiakumar N, Delzell E, Morrisey MA, Falkson C, Yong M, et al.: Mortality following bone metastasis and skeletal-related events among men with prostate cancer: a population-based analysis of US Medicare beneficiaries, 1999–2006. Prostate Cancer Prostatic Dis 14, 177–183, 2011.
   PubMed Web of Science ®Google Scholar
• Pendás-Franco N, González-Sancho JM, Suárez Y, Aguilera O, Steinmeyer A, et al.: Vitamin D regulates the phenotype of human breast cancer cells. Differentiation 75, 193–207, 2007.
   PubMed Web of Science ®Google Scholar
• Wang Q, Lee D, Sysounthone V, Chandraratna RAS, Christakos S, et al.: 1,25-dihydroxyvitamin D3 and retonic acid analogues induce differentiation in breast cancer cells with function- and cell-specific additive effects. Breast Cancer Res Treat 67, 157–168, 2001.
   PubMed Web of Science ®Google Scholar
• Lopes N, Carvalho J, Durães C, Sousa B, Gomes M, et al.: 1Alpha,25-dihydroxyvitamin D3 induces de novo E-cadherin expression in triple-negative breast cancer cells by CDH1-promoter demethylation. Anticancer Res 32, 249–257, 2012.
   PubMed Web of Science ®Google Scholar
• Mbalaviele G, Dunstan CR, Sasaki A, Williams PJ, Mundy GR, et al.: E-cadherin expression in human breast cancer cells suppresses the development of osteolytic bone metastases in an experimental metastasis model. Cancer Res 56, 4063–4070, 1996.
   PubMed Web of Science ®Google Scholar
• Yang JY, Zong CS, Xia W, Wei Y, Ali-Seyed M, et al.: MDM2 promotes cell motility and invasiveness by regulating E-cadherin degradation. Mol Cell Biol 26, 7269–7282, 2006.
   PubMed Web of Science ®Google Scholar
• Townsend K, Banwell CM, Guy M, Colston KW, Mansi JL, et al.: Autocrine metabolism of vitamin D in normal and malignant breast tissue. Clin Cancer Res 11, 3579–3586, 2005.
   PubMed Web of Science ®Google Scholar
• Theriault RL: Biology of bone metastases. Cancer Control 19, 92–101, 2012.
   PubMed Web of Science ®Google Scholar