Effect of Nutritional Supplementation Enriched with Eicosapentaenoic Acid on Inflammatory Profile of Patients With Oral Cavity Cancer in Antineoplastic Pretreatment: A Controlled and Randomized Clinical Trial

References

• World Health Organization: International Agency for Research on Cancer. Globocan 2012. Retrieved from http://globocan.iarc.fr/
   Google Scholar
• Instituto Nacional de Câncer José Alencar Gomes da Silva: Estimativa 2016-Incidência de câncer no Brasil. Retrieved from http://www.inca.gov.br/wcm/dncc/2015/index.asp
   Google Scholar
• Alshadwi A, Nadersbab M, Carlson ER, Young LS, Burke PA, et al.: Nutritional considerations for head and neck cancer patients: a review of the literature. J Oral Maxillofac Surg 71(11), 1853–1860, 2013.
   PubMed Web of Science ®Google Scholar
• Uster A, Ruefenacht U, Ruehlin M, Pless M, Siano M, et al.: Influence of a nutritional intervention on dietary intake and quality of life in cancer patients: a randomized controlled trial. Nutrition 29(11–12), 1342–1349, 2013.
   PubMed Web of Science ®Google Scholar
• Fearon K, Strasser F, Anker SD, Bosaeus I, Bruera E, et al.: Definition and classification of cancer cachexia: an international consensus. Lancet Oncol 12(5), 489–495, 2011.
   PubMed Web of Science ®Google Scholar
• Fearon KCH and Moses AG: Cancer cachexia. Int J Cardiol 85(1), 73–81, 2002.
   PubMed Web of Science ®Google Scholar
• Argilés JM, Moore-Carrasco R, Fuster G, Busquets S, and López-Soriano FJ: Cancer cachexia: the molecular mechanisms. Int J Biochem Cell Biol 35(4), 405–409, 2003.
   PubMed Web of Science ®Google Scholar
• Martin F, Santolaria F, Batista N, González-Reimers E, Brito MJ, et al.: Cytokine levels (IL-6 and IFN-gamma), acute phase response and nutritional status as prognostic factors in lung cancer. Cytokine 11(1), 80–86, 1999.
   PubMed Web of Science ®Google Scholar
• Argilés JM, López-Soriano FJ, and Busquets S: Novel approaches to the treatment of cachexia. Drug Discov Today 13(1–2), 73–78, 2008.
   PubMed Web of Science ®Google Scholar
• Murphy RA, Yeung E, and Mazurak VC: Influence of eicosapentaenoic acid supplementation on lean body mass in cancer cachexia. Br J Cancer 105(10), 1469–1473, 2011.
   PubMed Web of Science ®Google Scholar
• Pappalardo G, Almeida A, and Ravasco P: Eicosapentaenoic acid in cancer improves body composition and modulates metabolism. Nutrition 31(14), 549–455, 2015.
   PubMed Web of Science ®Google Scholar
• Sperling RI, Benincaso AI, Knoell CT, Larkin JK, Austen KF, et al.: Dietary u-3 polyunsaturated fatty acids inhibit phosphoinositide formation and chemotaxis in neutrophils. J Clin Invest 91(2), 651–660, 1993.
   PubMed Web of Science ®Google Scholar
• Schacky CV, Kiefl R, Jendraschak E, and Kaminski WE: N-3 fatty acids and cysteinyl-leukotriene formation in humans in vitro, ex vivo and in vivo. J Lab Clin Med 121(2), 302–309, 1993.
   PubMed Web of Science ®Google Scholar
• Babcock TA, Novak T, Ong E, Jho DH, Welton WS, et al.: Modulation of lipopolysaccharide stimulated macrophage tumor necrosis factor-a production by u-3 fatty acid is associated with differential cyclooxygenase-2 protein expression and is independent of interleukin-10. J Surg Res 107(1), 135–139, 2002.
   PubMed Web of Science ®Google Scholar
• De Caterina R, Cybulsky MI, Clinton SK, Gimbrone MA, and Libby P: The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells. Arterioscler Thromb 14(11), 1829–1836, 1994.
   PubMed Web of Science ®Google Scholar
• Khalfoun B, Thibault F, Watier H, Bardos P, and Lebranchu Y: Docosahexaenoic and eicosapentaenoic acids inhibit in vitro human endothelial cell production of interleukin-6. Adv Exp Biol Med 400, 589–597, 1997.
   Web of Science ®Google Scholar
• Caughey G, Mantzioris E, Gibson R, Clelnd L, and James M: The effect on human tumor necrosis factor alpha and interleukin 1 beta production of diets enriched in n-3 fatty acids from vegetable oil or fish oil. Am J Clin Nutr 63(1), 116–122, 1996.
   PubMed Web of Science ®Google Scholar
• Novak TE, Babcock TA, Jho DH, Helton WS, and Espat NJ: NF-kappa B inhibition by omega-3 fatty acids modulates LPS-stimulated macrophage TNFalpha transcription. Am J Physiol 284(1), 84–89, 2003.
   Web of Science ®Google Scholar
• Zhao Y, Joshi-Barve S, Barve S, and Chen LH: Eicosapentaenoic acid prevents LPS-induced TNF-alpha expression by preventing NF-kappaB activation. J Am Coll Nut 23(1), 71–78, 2004.
   PubMed Web of Science ®Google Scholar
• Peltola H and Valmari P: Serum C-reactive protein as detector of pretreated childhood bacterial meningitis. Neurology, 35(2), 251–253, 1085.
   PubMed Web of Science ®Google Scholar
• Doumas BT, Watson WA, and Biggs HG: Albumin standards and the measurement of serum albumin with bromcresol green. Clin Chim Acta 31(1), 87–96, 1971.
   PubMed Web of Science ®Google Scholar
• Corrêa CR, Angelili AO, Camargo NR, Barbosa L, and Burini RC: Comparação entre a relação PCR/albumina e o índice prognóstico inflamatório nutricional (IPIN). J Bras Patol Med Lab 38(3), 183–190, 2002.
   Google Scholar
• Ross PJ, Ashley S, Norton A, Priest K, Waters JS, et al.: Do patients with weight loss have a worse outcome when undergoing chemotherapy for lung cancer? Br J Cancer 90(10), 1905–1911, 2004.
   PubMed Web of Science ®Google Scholar
• Barber MD, Fearon KC, Tisdale MJ, McMillan DC, and Ross JA: Effect of a fish oil-enriched nutritional supplement on metabolic mediators in patients with pancreatic cancer cachexia. Nutr Cancer 40(2), 118–124, 2001.
   PubMed Web of Science ®Google Scholar
• Van der Meij B, Langius J, Smit E, Spreeuwenberg MD, von Blomberg BM, et al.: Oral nutritional supplements containing (n-3) polyunsaturated fatty acids affect the nutritional status of patients with stage III non-small cell lung cancer during multimodality treatment. J Nutr 140(10), 1774–1780, 2010.
   PubMed Web of Science ®Google Scholar
• Read JA, Beale PJ, Volker DH, Smith N, Childs A, et al.: Nutrition intervention using an eicosapenatenoic acid (EPA)-containing supplement in patients with advanced colorectal cancer. Effects on nutritional and inflammatory status: a phase II trial. Supp Care Cancer 15(3), 301–307, 2007.
   PubMed Web of Science ®Google Scholar
• Ke L, Xiang Y, Xia W, Yang J, Yu Y, et al. A prognostic model predicts the risk of distant metastasis and death for patients with nasopharyngeal carcinoma based on pre-treatment interleukin 6 and clinical stage. Clin Immunol 164, 45–51, 2016.
   PubMed Web of Science ®Google Scholar
• Skrinjar I, Brailo V, Vidovic-Juras D, Vucicevic-Boras V, and Milenovic A. Evaluation of pretreatment serum interleukin-6 and tumor necrosis factor alpha as a potential biomarker for recurrence in patients with oral squamous cell carcinoma. Med Oral Patol Oral Cir Bucal 20(4), 402–407, 2015.
   PubMed Web of Science ®Google Scholar
• Casas-Rodera, P, Gomez-Candela C, Benitez S, Mateo R, Armero M, et al.: Immunoenhanced enteral nutrition formulas in head and neck cancer surgery: a prospective, randomized clinical trial. Nutr Hosp 23(2), 105–110, 2008.
   PubMed Web of Science ®Google Scholar
• Silva JA, Trindade EB, Fabre ME, Mengotto VM, Gevaerd S, et al.: Fish oil supplement alters markers of inflammatory and nutritional status in colorectal cancer patients. Nutr Cancer 64(2), 267–273, 2012.
   PubMed Web of Science ®Google Scholar
• Finocchiaro C, Segre O, Fadda M, Monge T, Scigliano M, et al.: Effect of n-3 fatty acids on patients with advanced lung cancer: a double-blind, placebo-controlled study. Br J Nutr 108(2), 327–333, 2011.
   PubMed Web of Science ®Google Scholar
• Forrest LM, Mcmillan DC, Mcardle CS, Angerson WJ, and Dunlop DJ: Comparison of an inflammation-based prognostic score (GPS) with performance status (ECOG) in patient receiving platinum-based chemotherapy for inoperable nonsmall-cell lung cancer. Br J Cancer 90, 1704–1706, 2004.
   PubMed Web of Science ®Google Scholar
• Scott HR, Mcmillan DC, Forrest LM, Brown DJ, Mcardle CS, et al.: The systemic inflammatory response, weight loss, performance status and survival in patients with inoperable non-small cell lung cancer. Br J Cancer 87, 264–267, 2002.
   PubMed Web of Science ®Google Scholar
• de Luis DA, Izaola O, Cuella L, Terroba MC, de la Fuente B, et al.: A randomized clinical trial with two doses of a omega 3 fatty acids oral and arginine enhanced formula in clinical and biochemical parameters of head and neck cancer ambulatory patients. Eur Rev Med Pharmacol Sci 17(8), 1090–1094, 2013.
   PubMed Web of Science ®Google Scholar
• de Luis DA, de la Fuente B, Izaola O, Martin T, Cuellar L, et al.: Clinical effects of a hypercaloric and hyperproteic oral supplement enhanced with w3 fatty acids and dietary fiber in postsurgical ambulatory head and neck cancer patients. Nutr Hosp 31(2), 759–763, 2015.
   Web of Science ®Google Scholar
• Zhu MW, Tang DN, Hou J, Wei JM, Hua B, et al.: Impact of fish oil enriched total parenteral nutrition on elderly patients after colorectal cancer surgery. Chin Med J 125, 178–181, 2012.
   PubMed Web of Science ®Google Scholar
• Braga M, Gianotti L, Vignali A, and Carlo VD. Preoperative oral arginine and fatty acid supplementation improves the immunometabolic host response and outcome after colorectal resection for cancer. Surgery 132(5), 805–814, 2002.
   PubMed Web of Science ®Google Scholar