620
Views
42
CrossRef citations to date
0
Altmetric
Articles

Antigenotoxicity and Cytotoxic Potentials of Metabiotics Extracted from Isolated Probiotic, Lactobacillus rhamnosus MD 14 on Caco-2 and HT-29 Human Colon Cancer Cells

, &
Pages 110-119 | Received 09 Mar 2019, Accepted 02 May 2019, Published online: 03 Jul 2019

References

  • Kumar KS, Sastry N, Polaki H, and Mishra V: Colon cancer prevention through probiotics: an overview. J Cancer Ther 7, 81–92, 2015.
  • Cancer Facts and Figures. Cancer Facts and Figures 2016. Atlanta, GA: American Cancer Society, 2016.
  • Prakash S, Rodes L, Coussa-Charley M, and Tomaro-Duchesneau C: Gut microbiota: next frontier in understanding human health and development of biotherapeutics. Biologics 5, 71–86, 2011.
  • Brown K, DeCoffe D, Molcan E, and Gibson DL: Diet-induced dysbiosis of the intestinal microbiota and the effects on immunity and disease. Nutrients 4, 1095–1119, 2012.
  • Stecher B, Maier L, and Hardt WD: ‘Blooming’ in the gut: how dysbiosis might contribute to pathogen evolution. Nat Rev Microbiol 11, 277–284, 2013.
  • Goyal N, and Shukla G: Probiotic Lactobacillus rhamnosus GG modulates the mucosal immune response in Giardia intestinalis-Infected BALB/c Mice. Dig Dis Sci 58, 1218–1225, 2013. doi:10.1007/s10620-012-2503-y
  • Raman M, Ambalam P, Kondepudi KK, Pithva S, Kothari C, et al.: Potential of probiotics, prebiotics and synbiotics for management of colorectal cancer. Gut Microbes 4, 181–192, 2013.
  • Verma A, and Shukla G: Synbiotic (Lactobacillus rhamnosus + Lactobacillus acidophilus + inulin) attenuates oxidative stress and colonic damage in 1,2 dimethylhydrazine dihydrochloride-induced colon carcinogenesis in Sprague-Dawley rats: a long-term study. Eur J Cancer Prev 23, 550–559, 2014.
  • Shukla G, Bhatia R, and Sharma A: Prebiotic inulin supplementation modulates the immune response and restores gut morphology in Giardia duodenalis infected malnourished mice. Parasitol Res 115, 4189–4198, 2016. doi: 10.1007/s00436-016-5196-x
  • Boyle RJ, Roy MB, and Mimi LK: Probiotic use in clinical practice: what are the risks? Am J Clin Nutr 83, 1256–1264, 2006.
  • Doron S, and Snydman DR: Risk and safety of probiotics. Clin Infect Dis 60, S129–S134, 2015.
  • Shenderov BA: Metabiotics: novel idea or natural development of probiotic conception. Microb Ecol Health Dis 24, 20399, 2013.
  • Bomba A, Brandeburova A, Ricanyova J, Strojny L, Chmelarova A, et al.: The role of probiotics and natural bioactive compounds in modulation of the common molecular pathways in pathogenesis of atherosclerosis and cancer. Biologia 67, 1–13, 2012.
  • Sharma M, and Shukla G: Metabiotics: one step ahead of probiotics; an insight into mechanisms involved in anticancerous effect in colorectal cancer. Front Microbiol 7, 1940, 2016.
  • Beloborodova NV, and Osipov GA: Small molecules originating from microbes (SMOM) and their role in microbes-host relationship. Microb Ecol Health Dis 12, 12–21, 2000.
  • Escamilla J, Lane MA, and Maitin V: Cell-free supernatants from probiotic Lactobacillus casei and Lactobacillus rhamnosus GG decrease colon cancer cell invasion in vitro. Nutr Cancer 64, 871–878, 2012.
  • Lankaputhra WE, and Shah NP: Antimutagenic properties of probiotic bacteria and of organic acids. Mutat Res 397, 169–182, 1998.
  • Davis C, and Milner J: Gastrointestinal microflora, food components and colon cancer prevention. J Nutr Biochem 20, 743–752, 2009.
  • Yu DCW, Waby JS, Chirakkal H, Staton CA, and Corfe BM: Butyrate suppresses expression of neuropilin I in colorectal cell lines through inhibition of Sp1 transactivation. Mol Cancer 9, 276–289, 2010.
  • Prisciandaro LD, Geier MS, Chua AE, Butler RN, and Cummins AG: Probiotic factors partially prevent changes to caspases 3 and 7 activation and transepithelial electrical resistance in a model of 5-fluorouracil-induced epithelial cell damage. Support Care Cancer 20, 520–523, 2012.
  • Wan Y, Xin YI, Zhang C, Wu D, Ding D, et al. Fermentation supernatants of Lactobacillus delbrueckii inhibit growth of human colon cancer cells and induce apoptosis through a caspase 3-dependent pathway. Oncol Lett 7, 1738–1742, 2014.
  • Key TJ, Schatzkin A, Willett WC, Allen NE, Spencer EA, et al.: Diet, nutrition and the prevention of cancer. Public Health Nutr 7, 187–200, 2004.
  • Fajardo AM, and Piazza GA: Chemoprevention in gastrointestinal physiology and disease. Anti-inflammatory approaches for colorectal cancer chemoprevention. Am J Physiol Gastrointest Liver Physiol 309, G59–G70, 2015.
  • Aliabadi SH, Mohammadi F, Fazeli H, and Mirlohi M: Effects of Lactobacillus plantarum A7 with probiotic potential on colon cancer and normal cells proliferation in comparison with a commercial strain. Iran J Basic Med Sci 17, 815–819, 2014.
  • Quillardet P, de Bellecombe C, and Hofnung M: The SOS Chromotest, a colorimetric bacterial assay for genotoxins: validation study with 83 compounds. Mutat Res 147, 79–95, 1985.
  • Phonnok S, Wanlaya UT, and Wongsatayanon BT: Anticancer and apoptosis-inducing activities of microbial metabolites. Electron J Biotechnol 13, 2010.
  • Ma EL, Choi YJ, Choi J, Pothoulakis C, Rhee SH, et al. The anticancer effect of probiotic Bacillus polyfermenticus on human colon cancer cells is mediated through ErbB2 and ErbB3 inhibition. Int J Cancer 127, 780–790, 2010.
  • Culligan EP, Colin H, and Roy DS: Probiotics and gastrointestinal disease: successes, problems and future prospects. Gut Pathog 23, 1–19, 2009.
  • Suda H, Hara K, and Miyamoto T: Binding of mutagens to exopolysaccharide produced by Lactobacillus plantarum mutant strain 301102S. J Dairy Sci 91, 2960–2966, 2008.
  • Kim Y, Lee D, Kim D, Cho J, Yang J, et al. Inhibition of proliferation in colon cancer cell lines and harmful enzyme activity of colon bacteria by Bifidobacterium adolescentis SPM0212. Arch Pharm Res 1, 468–473, 2008.
  • Nami Y, Haghshenas B, Haghshenas M, Abdullah N, and Yari KA: The prophylactic effect of probiotic Enterococcus lactis IW5 against different human cancer cells. Front Microbiol 6, 1317, 2015.
  • Scharlau D, Borowicki A, Habermann N, Hofmann T, Klenow S, et al.: Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre. Mutat Res 682, 39–53, 2009.
  • Chen Y-x, Fang J-y, Lu J, and Qiu D-k: Regulation of histone acetylation on the expression of cell cycle-associated genes in human colon cancer cell lines. Zhonghua Yi Xue Za Zhi 84, 312–317, 2004.
  • Jan G, Belzacq A-S, Haouzi D, Rouault A, Métivier D, et al.: Propionibacteria induce apoptosis of colorectal carcinoma cells via short-chain fatty acids acting on mitochondria. Cell Death Differ 9, 179–188, 2002.
  • Lan A, Gossmann LD, Lemaire C, Brenner C, and Jan G: Acidic extracellular pH shifts colorectal cancer cell death from apoptosis to necrosis upon exposure to propionate and acetate, major end-products of the human probiotic propionibacteria. Apoptosis 12, 573–591, 2007.
  • Yan F, Cao H, Cover TL, Whitehead R, Washington MK, et al.: Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth. Gastroenterol 132, 562–575, 2007.
  • Nepelska M, Wouters T, Jacouton E, Beguet-Crespel F, Lapaque N, et al.: Commensal gut bacteria modulate phosphorylation-dependent PPARγ transcriptional activity in human intestinal epithelial cells. Sci Rep 7, 43199, 2017.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.