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Original Articles

The NCI-N87 Cell Line as a Gastric Epithelial Model to Study Cellular Uptake, Trans-Epithelial Transport, and Gastric Anti-Inflammatory Properties of Anthocyanins

, , ORCID Icon, , &
Pages 686-695 | Received 02 May 2018, Accepted 12 Jul 2019, Published online: 29 Jul 2019

References

  • Prior RL and Wu X: Anthocyanins: structural characteristics that result in unique metabolic patterns and biological activities. Free Radic Res 40, 1014–1028, 2006. [Internet]. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17015246
  • Rice-Evans CA, Miller NJ, and Paganga G: Antioxidant properties of phenolic compounds. Trends Plant Sci 2, 152–159, 1997.
  • Zamora-Ros R, Agudo A, Lujan-Barroso L, Romieu I, Ferrari P, et al.: Dietary flavonoid and lignan intake and gastric adenocarcinoma risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Am J Clin Nutr 96, 1398–1408, 2012.
  • Hertog MGL, Feskens EJM, Kromhout D, Hertog MGL, Hollman PCH, et al.: Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Lancet 342, 1007–1011, 1993.
  • Kamonpatana K, Giusti MM, Chitchumroonchokchai C, MorenoCruz M, Riedl KM, et al.: Susceptibility of anthocyanins to ex vivo degradation in human saliva. Food Chem 135, 738–747, 2012. doi:10.1016/j.foodchem.2012.04.110
  • Castañeda-Ovando A, Pacheco-Hernández MDL, Páez-Hernández ME, Rodríguez JA, and Galán-Vidal CA: Chemical studies of anthocyanins: A review. Food Chem 113, 859–871, 2009.
  • Andersen ØM and Jordheim M: Basic anthocyanin chemistry and dietary sources. In: Anthocyanins Heal Dis., Wallace TC and Giusti MM (eds.). 1st ed. Boca Raton, FL: CRC Press (Taylor & Francis Group), 2014, pp. 13–90.
  • Tsuda T, Horio F, and Osawa T: Absorption and metabolism of cyanidin 3-O-beta-D-glucoside in rats. FEBS Lett 449, 179–182, 1999.
  • Milbury PE, Cao G, Prior RL, and Blumberg J: Bioavailablility of elderberry anthocyanins. Mech Ageing Dev 123, 997–1006, 2002.
  • Passamonti S, Vrhovsek U, Vanzo A, and Mattivi F: The stomach as a site for anthocyanins absorption from food. FEBS Lett 544, 210–213, 2003.
  • Talavera S, Felgines C, Texier O, Besson C, Gil-Izquierdo A, et al.: Anthocyanin metabolism in rats and their distribution to digestive area, kidney, and brain. J Agric Food Chem 53, 3902–3908, 2005.
  • Fernandes I, de Freitas V, Reis C, and Mateus N: A new approach on the gastric absorption of anthocyanins. Food Funct 3, 508–516, 2012. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22391951
  • Fang J: Some anthocyanins could be efficiently absorbed across the gastrointestinal mucosa: Extensive presystemic metabolism reduces apparent bioavailability. J Agric Food Chem 62, 3904–3911, 2014.
  • Phelan K and May KM: Basic techniques in mammalian cell tissue culture. Curr Protoc Cell Biol 66, 1.1.1–1.22, 2015.
  • Oliveira H, Fernandes I, Brás NF, Faria A, De Freitas V, et al.: Experimental and theoretical data on the mechanism by which red wine anthocyanins are transported through a human MKN-28 gastric cell model. J Agric Food Chem 63, 7685–7692, 2015.
  • Japanese Collection of Research Bioresources Cell Bank. JCRB0253 MKN28. Natl Institutes. Biomed Innov Heal Nutr 2015. [Internet]. [cited 2017 Mar 1]. Available from: http://cellbank.nibiohn.go.jp/∼cellbank/en/search_res_det.cgi?ID=340#
  • Lemieux M, Bouchard F, Gosselin P, Paquin J, and Mateescu MA: The NCI-N87 cell line as a gastric epithelial barrier model for drug permeability assay. Biochem Biophys Res Commun 412, 429–434, 2011. doi:10.1016/j.bbrc.2011.07.106
  • Park JG, Frucht H, LaRocca RV, Bliss DP, Jr. Kurita Y, et al.: 1990. Characteristics of cell lines established from human gastric carcinoma. Cancer Res 50, 2773–2780. Available from: http://www.ncbi.nlm.nih.gov/pubmed/2158397
  • Chailler P and Ménard D: Establishment of human gastric epithelial (HGE) cell lines exhibiting barrier function, progenitor, and prezymogenic characteristics. J Cell Physiol 202, 263–274, 2005.
  • Conlin VS, Curtis SB, Zhao Y, Moore EDW, Smith VC, et al.: Helicobacter pylori infection targets adherens junction regulatory proteins and results in increased rates of migration in human gastric epithelial cells. Infect Immun 72, 5181–5192, 2004.
  • Kim JM, Kim KM, Park EH, Seo JH, Song JY, et al.: Anthocyanins from black soybean inhibit Helicobacter pylori-induced inflammation in human gastric epithelial AGS cells. Microbiol Immunol 57, 366–373, 2013.
  • Rodríguez-Saona LE and Wrolstad RE: 2001. Extraction, isolation, and purification of anthocyanins. In: Curr Protoc Food Anal Chem, Wrolstad RE, Acree TE, An H, Decker EA, Penner MH, Reid DS, Schwartz SJ, Shoemaker CF, and Sporns P (eds.). 1st ed. New York, NY: John Wiley & Sons, Inc.; pp. F1.1.1–F1.1.11.
  • He J and Giusti MM: High-purity isolation of anthocyanins mixtures from fruits and vegetables – a novel solid-phase extraction method using mixed mode cation-exchange chromatography. J Chromatogr A 1218, 7914–7922, 2011.
  • Jovov B, Wills NK, and Lewis SA: A spectroscopic method for assessing confluence of epithelial cell cultures. Am J Physiol Cell Physiol 30, C1196–C1203, 1991. Available from: http://cat.inist.fr/?aModele=afficheN&cpsidt=5027446
  • Gagnon M, Zihler Berner A, Chervet N, Chassard C, and Lacroix C: Comparison of the Caco-2, HT-29 and the mucus-secreting HT29-MTX intestinal cell models to investigate Salmonella adhesion and invasion. J Microbiol Methods 94, 274–279, 2013. doi:10.1016/j.mimet.2013.06.027
  • Wu X, Gu L, Prior RL, McKay S, Nakajima J, et al.: Characterization of anthocyanins and proanthocyanidins in some cultivars of Ribes, Aronia, and Sambucus and their antioxidant capacity. J Agric Food Chem 52, 7846–7856, 2004. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1082896/pdf/S1110724304404045.pdf
  • Yandrapu H and Sarosiek J: Protective factors of the gastric and duodenal mucosa: an overview. Curr Gastroenterol Rep 17, 1–8, 2015.
  • Atnip A, Sigurdson GT, Bomser J, and Giusti MM: Time, concentration, and pH-dependent transport and uptake of anthocyanins in a human gastric epithelial (NCI-N87) cell line. IJMS 18, 446–458, 2017. Available from: http://www.mdpi.com/1422-0067/18/2/446
  • Passamonti S, Vrhovsek U, and Mattivi F: The interaction of anthocyanins with bilitranslocase. Biochem Biophys Res Commun 296, 631–636, 2002.
  • Sigurdson GT, Atnip A, Bomser J, and Giusti MM: Aglycone structures and glycosylations affect anthocyanin transport and uptake in human gastric epithelial (NCI-N87) cells. J Food Compos Anal 65, 33–39, 2018.
  • Gu LC, Erdös EA, Chiang HS, Calderwood T, Tsai K, et al.: Stability of interleukin 1β (IL-1β) in aqueous solution: analytical methods, kinetics, products, and solution formulation implications. Pharm Res 8, 485–490, 1991.

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