Cytotoxic Activity of Boesenbergia rotunda Extracts against Nasopharyngeal Carcinoma Cells (HK1). Cardamonin, a Boesenbergia rotunda Constituent, Inhibits Growth and Migration of HK1 Cells by Inducing Caspase-Dependent Apoptosis and G2/M–Phase Arrest

References

• Han P, Chen R-H, Wang F, Zeng J-Y, Yu S-T, Xu L-H, Cai Q, Liang F-Y, Xia T-L, Lin Z-R, et al. Novel chimeric transcript RRM2-c2orf48 promotes metastasis in nasopharyngeal carcinoma. Cell Death Dis. 2017;8(9):e3047. doi:10.1038/cddis.2017.402
   PubMed Web of Science ®Google Scholar
• Newman DJ, Cragg GM. Natural products as sources of new drugs from 1981 to 2014. J Nat Prod. 2016;79(3):629–61. doi:10.1021/acs.jnatprod.5b01055
   PubMed Web of Science ®Google Scholar
• Eng-Chong T, Yean-Kee L, Chin-Fei C, Choon-Han H, Sher-Ming W, Li-Ping CT, Gen-Teck F, Khalid N, Abd Rahman N, Karsani SA, et al. Boesenbergia rotunda: From ethnomedicine to drug discovery. Evid-Based Complement Altern Med. 2012;2012:1–25. doi:10.1155/2012/473637
   Web of Science ®Google Scholar
• Jing LJ, Mohamed M, Rahmat A, Bakar MFA. Phytochemicals, antioxidant properties and anticancer investigations of the different parts of several gingers species (Boesenbergia rotunda, Boesenbergia pulchella var attenuata and Boesenbergia armeniaca). J Med Plants Res. 2010;4:27–32.
   Google Scholar
• Kirana C, Record IR, McIntosh GH, Jones GP. Screening for antitumor activity of 11 species of Indonesian Zingiberaceae using human MCF-7 and HT-29 cancer cells. Pharm Biol. 2003;41(4):271–6. doi:10.1076/phbi.41.4.271.15673
   Web of Science ®Google Scholar
• Sukari MA, Ching AYL, Lian GEC, Rahmani M, Khalid K. Cytotoxic constituents from Boesenbergia pandurata (roxb.) schltr. Nat Prod Sci. 2007;13:110–3.
   Google Scholar
• Isa NM, Abdul AB, Abdelwahab SI, Abdullah R, Sukari MA, Kamalidehghan B, Hadi AHA, Mohan S. Boesenbergin A, a chalcone from Boesenbergia rotunda induces apoptosis via mitochondrial dysregulation and cytochrome c release in A549 cells in vitro: Involvement of HSP70 and Bcl2/Bax signalling pathways. J Funct Foods. 2013;5(1):87–97. doi:10.1016/j.jff.2012.08.008
   Web of Science ®Google Scholar
• James S, Aparna JS, Paul AM, Lankadasari MB, Mohammed S, Binu VS, Santhoshkumar TR, Reshmi G, Harikumar KB. Cardamonin inhibits colonic neoplasia through modulation of MicroRNA expression. Sci Rep. 2017;7(1):13945. doi:10.1038/s41598-017-14253-8
   PubMed Web of Science ®Google Scholar
• Mohammed IA, Akhtar MN, Biau FJ, Tor YS, Zareen S, Binti Shahabudin S, Binti Abd Hamid H, Ul Haq Z, Khalil R, Khalaf RM, et al. Isolation of cardamonin and pinostrobin chalcone from the rhizomes of Boesenbergia rotunda (L.) Mansf. and their cytotoxic effects on H-29 and MDA-MB-231 cancer cell lines. Nat Prod J. 2019;9(4):341–8. doi:10.2174/2210315509666190117151542
   Web of Science ®Google Scholar
• Huang DP, Ho JHC, Poon YF, Chew EC, Saw D, Lui M, Li CL, Mak LS, Lai SH, Lau WH, et al. Establishment of a cell line (NPC/HK1) from a differentiated squamous carcinoma of the nasopharynx. Int J Cancer. 1980;26(2):127–32. doi:10.1002/ijc.2910260202
   PubMed Web of Science ®Google Scholar
• Ching AYL, Wah TS, Sukari MA, Lian GEC, Rahmani M, et al. Characterization of flavonoid derivatives from Boesenbergia rotunda (L.). Malaysian J Anal Sci. 2007;11:154–9.
   Google Scholar
• Morikawa T, Funakoshi K, Ninomiya K, Yasuda D, Miyagawa K, Matsuda H, Yoshikawa M. Medicinal foodstuffs. XXXIV. Structures of new prenylchalcones and prenylflavanones with TNF-α; and aminopeptidase N inhibitory activities from Boesenbergia rotunda. Chem Pharm Bull. 2008;56(7):956–62. doi:10.1248/cpb.56.956
   PubMed Web of Science ®Google Scholar
• Park S, Gwak J, Han SJ, Oh S. Cardamonin suppresses the proliferation of colon cancer cells by promoting β-catenin degradation. Biol Pharm Bull. 2013;36:1040–4.
   PubMed Web of Science ®Google Scholar
• Gonçalves LM, Valente IM, Rodrigues JA. An overview on cardamonin. J Med Food. 2014;17(6):633–40. doi:10.1089/jmf.2013.0061
   PubMed Web of Science ®Google Scholar
• Niu P-G, Zhang Y-X, Shi D-H, Liu Y, Chen Y-Y, Deng J. Cardamonin inhibits metastasis of Lewis lung carcinoma cells by decreasing mTOR activity. PLoS One. 2015;10(5):e0127778. doi:10.1371/journal.pone.0127778
   PubMed Web of Science ®Google Scholar
• Nandakumar N, Muthuraman S, Gopinath P, Nithya P, Gopas J, Kumar RS. Synthesis of coumaperine derivatives: Their NF-κB inhibitory effect, inhibition of cell migration and their cytotoxic activity. Eur J Med Chem. 2017;125:1076–87. doi:10.1016/j.ejmech.2016.10.047
   PubMed Web of Science ®Google Scholar
• Nomura M, Takahashi T, Uesugi A, Tanaka R, Kobayashi S. Inotodiol, a lanostane triterpenoid, from Inonotus obliquus inhibits cell proliferation through caspase-3-dependent apoptosis. Anticancer Res. 2008;28(5A):2691–6.
   PubMed Web of Science ®Google Scholar
• Gong L, Tang Y, An R, Lin M, Chen L, Du J. RTN1-C mediates cerebral ischemia/reperfusion injury via ER stress and mitochondria-associated apoptosis pathways. Cell Death Dis. 2017;8(10):e3080. doi:10.1038/cddis.2017.465
   PubMed Web of Science ®Google Scholar
• Ichim G, Tait SWG. A fate worse than death: apoptosis as an oncogenic process. Nat Rev Cancer. 2016;16(8):539–48. doi:10.1038/nrc.2016.58
   PubMed Web of Science ®Google Scholar
• Henry-Mowatt J, Dive C, Martinou J-C, James D. Role of mitochondrial membrane permeabilization in apoptosis and cancer. Oncogene. 2004;23(16):2850–60. doi:10.1038/sj.onc.1207534
   PubMed Web of Science ®Google Scholar
• Ding D, Guo Y-R, Wu R-L, Qi W-Y, Xu H-M. Two new isoquinoline alkaloids from Scolopendra subspinipes mutilans induce cell cycle arrest and apoptosis in human glioma cancer U87 cells. Fitoterapia. 2016;110:103–9. doi:10.1016/j.fitote.2016.03.004
   PubMed Web of Science ®Google Scholar