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Article

Açaí (Euterpe oleracea Martius) Promotes Jejunal Tissue Regeneration by Enhancing Antioxidant Response in 5-Fluorouracil-Induced Mucositis

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Pages 523-533 | Received 12 Feb 2019, Accepted 02 Apr 2020, Published online: 05 May 2020

References

  • Sonis ST. The pathobiology of mucositis. Nat Rev Cancer. 2004;4(4):277–84. doi:10.1038/nrc1318
  • Sonis ST, Elting LS, Keefe D, Peterson DE, Schubert M, Hauer-Jensen M, Bekele BN, Raber-Durlacher J, Donnelly JP, Rubenstein EB, et al. Perspectives on cancer therapy-induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients. Cancer. 2004;100(S9):1995–2025.,.: doi:10.1002/cncr.20162
  • Longley DB, Harkin DP, Johnston PG. 5-fluorouracil: mechanisms of action and clinical strategies. Nat Rev Cancer. 2003;3(5):330–8. doi:10.1038/nrc1074
  • Yasuda M, Kato S, Yamanaka N, Iimori M, Matsumoto K, Utsumi D, Kitahara Y, Amagase K, Horie S, Takeuchi K, et al. 5-HT3 receptor antagonists ameliorate 5-fluorouracil-induced intestinal mucositis by suppression of apoptosis in murine intestinal crypt cells. Br J Pharmacol. 2013;168(6):1388–400.: doi:10.1111/bph.12019
  • Schauss AG, Wu X, Prior RL, Ou B, Patel D, Huang D, Kababick JP. Phytochemical and nutrient composition of the freeze-dried amazonian palm berry, Euterpe oleraceae mart. (Açaí). J Agric Food Chem. 2006;54(22):8598–603. doi:10.1021/jf060976g
  • Menezes E, Torres AT, Sabaa Srur AU. Lyophilized açaí pulp (Euterpe oleracea, Mart.) nutritional value. Acta Amaz. 2008;38(2):311–6. doi:10.1590/S0044-59672008000200014
  • Silva HRd, Assis DCd, Prada AL, Keita H, Amado JRR, et al. Euterpe oleracea Mart. (aai): an old known plant with a new perspective. Afr J Pharm Pharmacol. 2016;10:995–1006.:
  • Schauss AG, Wu X, Prior RL, Ou B, Huang D, Owens J, Agarwal A, Jensen GS, Hart AN, Shanbrom E, et al. Antioxidant capacity and other bioactivities of the freeze-dried Amazonian palm berry, Euterpe oleraceae mart. (Açaí). J Agric Food Chem. 2006;54(22):8604–10.: doi:10.1021/jf0609779
  • Spada PD, de Souza GG, Bortolini GV, Henriques JA, Salvador M. Antioxidant, mutagenic, and antimutagenic activity of frozen fruits. J Med Food. 2008;11(1):144–51. doi:10.1089/jmf.2007.598
  • Hogan S, Chung H, Zhang L, Li J, Lee Y, Dai Y, Zhou K. Antiproliferative and antioxidant properties of anthocyanin-rich extract from açai. Food Chem . 2010;118(2):208–14. doi:10.1016/j.foodchem.2009.04.099
  • Zielinski AA, Avila S, Ito V, Nogueira A, Wosiacki G, et al. The association between chromaticity, phenolics, carotenoids, and in vitro antioxidant activity of frozen fruit pulp in Brazil: an application of chemometrics. J Food Sci. 2014;79:510–6.:
  • Oliveira de Souza M, Silva M, Silva ME, de Paula Oliveira R, Pedrosa ML. Diet supplementation with Açaí (Euterpe oleracea Mart.) pulp improves biomarkers of oxidative stress and the serum lipid profile in rats. Nutrition. 2010;26(7-8):804–10. doi:10.1016/j.nut.2009.09.007
  • Xie C, Kang J, Burris R, Ferguson ME, Schauss AG, Nagarajan S, Wu X. Açaí juice attenuates atherosclerosis in ApoE deficient mice through antioxidant and anti-inflammatory activities. Atherosclerosis. 2011;216(2):327–33. doi:10.1016/j.atherosclerosis.2011.02.035
  • de Moura RS, Ferreira TS, Lopes AA, Pires KMP, Nesi RT, Resende AC, Souza PJC, da Silva AJR, Borges RM, Porto LC, et al. Effects of Euterpe oleracea Mart. (AÇAÍ) extract in acute lung inflammation induced by cigarette smoke in the mouse. Phytomedicine. 2012;19(3-4):262–9. doi:10.1016/j.phymed.2011.11.004
  • Bonomo L. d F, Silva DN, Boasquivis PF, Paiva FA, Guerra J. F d C, Martins TAF, de Jesus Torres ÁG, de Paula ITBR, Caneschi WL, Jacolot P, et al. Açaí (Euterpe oleracea Mart.) modulates oxidative stress resistance in Caenorhabditis elegans by direct and indirect mechanisms. PLoS One. 2014;9(3):e89933.: doi:10.1371/journal.pone.0089933
  • Barbosa PO, Pala D, Silva CT, de Souza MO, do Amaral JF, Vieira RAL, Folly G. A d F, Volp ACP, de Freitas RN. Açaí (Euterpe oleracea Mart.) pulp dietary intake improves cellular antioxidant enzymes and biomarkers of serum in healthy women. Nutrition. 2016;32(6):674–80. doi:10.1016/j.nut.2015.12.030
  • Day BJ. Antioxidant therapeutics: Pandora’s box. Free Radic Biol Med. 2014;66:58–64. doi:10.1016/j.freeradbiomed.2013.05.047
  • Holderness J, Schepetkin IA, Freedman B, Kirpotina LN, Quinn MT, Hedges JF, Jutila MA. Polysaccharides Isolated from Açaí Fruit Induce Innate Immune Responses. PLoS One. 2011;6(2):e17301. doi:10.1371/journal.pone.0017301
  • Reeves PG, Nielsen FH, Fahey GC. Jr: AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr. 1993;123(11):1939–51. doi:10.1093/jn/123.11.1939
  • Ferraris RP, Villenas SA, Diamond J. Regulation of brush-border enzyme activities and enterocyte migration rates in mouse small intestine. Am J Physiol. 1992;262:1047–59.
  • Williams JM, Duckworth CA, Vowell K, Burkitt MD, Pritchard DM. Intestinal Preparation Techniques for Histological Analysis in the Mouse. Curr Protoc Mouse Biol. 2016;6(2):148–68. doi:10.1002/cpmo.2
  • Soares PMG, Mota JMSC, Gomes AS, Oliveira RB, Assreuy AMS, Brito GAC, Santos AA, Ribeiro RA, Souza MHLP. Gastrointestinal dysmotility in 5-fluorouracil-induced intestinal mucositis outlasts inflammatory process resolution. Cancer Chemother Pharmacol. 2008;63(1):91–8. doi:10.1007/s00280-008-0715-9
  • Madesh M, Balasubramanian KA. Microtiter plate assay for superoxide dismutase using MTT reduction by superoxide. Indian J Biochem Biophys. 1998;35(3):184–8.
  • Lowry OH, Rosebrough NJ, Farr AL, Randall R. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951;193(1):265–75.
  • Aebi H. Catalase in vitro. Meth Enzymol. 1984;105:121–6. doi:10.1016/s0076-6879(84)05016-3
  • Sedlak J, Lindsay RH. Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman’s reagent. Anal Biochem. 1968;25:192–205. doi:10.1016/0003-2697(68)90092-4
  • Gibson RJ, Keefe DM. Cancer chemotherapy-induced diarrhoea and constipation: mechanisms of damage and prevention strategies. Support Care Cancer. 2006;14(9):890–900. doi:10.1007/s00520-006-0040-y
  • Generoso SdV, Rodrigues NM, Trindade LM, Paiva NC, Cardoso VN, Carneiro CM, Ferreira AVdM, Faria AMC, Maioli TU. Dietary supplementation with omega-3 fatty acid attenuates 5-fluorouracil induced mucositis in mice. Lipids Health Dis. 2015;14(1): 54. doi:10.1186/s12944-015-0052-z
  • Barros PAVd, Generoso SdV, Andrade MER, da Gama MAS, Lopes FCF, de Sales e Souza ÉL, Martins FdS, Miranda SEM, Fernandes SOA, Cardoso VN, et al. Effect of Conjugated Linoleic Acid-enriched Butter After 24 hours of Intestinal Mucositis Induction. Nutr Cancer. 2017;69(1):168–75.: doi:10.1080/01635581.2016.1225100
  • Song MK, Park MY, Sung MK. 5-Fluorouracil-induced changes of intestinal integrity biomarkers in BALB/c mice. J Cancer Prev. 2013;18(4):322–9. doi:10.15430/JCP.2013.18.4.322
  • Han X, Wu Z, Di J, Pan Y, Zhang H, Du Y, Cheng Z, Jin Z, Wang Z, Zheng Q, et al. CXCL9 attenuated chemotherapy-induced intestinal mucositis by inhibiting proliferation and reducing apoptosis. Biomed Pharmacother. 2011;65(8):547–54.: doi:10.1016/j.biopha.2011.03.008
  • Keefe D, Brealey J, Goland G, Cummins A. Chemotherapy for cancer causes apoptosis that precedes hypoplasia in crypts of the small intestine in humans. Gut. 2000;47(5):632–7. doi:10.1136/gut.47.5.632
  • Leocádio PCL, Antunes MM, Teixeira LG, Leonel AJ, Alvarez-Leite JI, Machado DCC, Generoso SV, Cardoso VN, Correia MITD. L-arginine pretreatment reduces intestinal mucositis as induced by 5-FU in mice. Nutr Cancer. 2015;67(3):486–93. doi:10.1080/01635581.2015.1004730
  • Al-Asmari AK, Khan AQ, Al-Asmari SA, Al-Rawi A, Al-Omani S. Alleviation of 5-fluorouracil-induced intestinal mucositis in rats by vitamin E via targeting oxidative stress and inflammatory markers. J Complement Integr Med. 2016;13(4):377–85. doi:10.1515/jcim-2016-0043
  • Cheah KY, Howarth GS, Yazbeck R, Wright TH, Whitford EJ, Payne C, Butler RN, Bastian SEP. Grape seed extract protects IEC-6 cells from chemotherapy-induced cytotoxicity and improves parameters of small intestinal mucositis in rats with experimentally-induced mucositis. Cancer Biol Ther. 2009;8(4):382–90. doi:10.4161/cbt.8.4.7453
  • Ferreira TM, Leonel AJ, Melo MA, Santos RRG, Cara DC, Cardoso VN, Correia MITD, Alvarez-Leite JI. Oral supplementation of butyrate reduces mucositis and intestinal permeability associated with 5-Fluorouracil administration. Lipids. 2012;47(7):669–78. doi:10.1007/s11745-012-3680-3
  • Whittaker AL, Zhu Y, Howarth GS, Loung CS, Bastian SEP, Wirthensohn MG. Effects of commercially produced almond by-products on chemotherapy-induced mucositis in rats. WJGP. 2017;8(4):176–87. doi:10.4291/wjgp.v8.i4.176
  • Ribeiro JC, Antunes LMG, Aissa AF, Darin JDC, De Rosso VV, Mercadante AZ, Bianchi MLP. Evaluation of the genotoxic and antigenotoxic effects after acute and subacute treatments with Açaí pulp (Euterpe oleracea Mart.) on mice using the erythrocytes micronucleus test and the comet assay. Mutat Res. 2010;695(1-2):22–8. doi:10.1016/j.mrgentox.2009.10.009
  • Kang MH, Kim BH. Oral Wound Healing Effects of Açaí Berry Water Extracts in Rat Oral Mucosa. ToxicolRes. 2018;34(2):97–102. doi:10.5487/TR.2018.34.2.097
  • Fournier BM, Parkos CA. The role of neutrophils during intestinal inflammation. Mucosal Immunol. 2012;5(4):354–66. doi:10.1038/mi.2012.24
  • Ribeiro SMR, de Queiroz JH, Pelúzio MCG, Costa NMB, da Matta SLP, de Queiroz MELR. A formação e os efeitos das espécies reativas de oxigênio no meio biológico. Biosci J. 2005;21:133–49.:
  • Rtibi K, Selmi S, Grami D, Amri M, Sebai H, Marzouki L. Contribution of oxidative stress in acute intestinal mucositis induced by 5 fluorouracil (5-FU) and its pro-drug capecitabine in rats. Toxicol Mech Methods. 2018;28(4):262–7. doi:10.1080/15376516.2017.1402976
  • Ellman GL. Tissue sulfhydryl groups. Arch Biochem Biophys. 1959;82(1):70–7. doi:10.1016/0003-9861(59)90090-6
  • Knorre D, Kudryashova N, Godovikova T. Chemical and Functional Aspects of Posttranslational Modification of Proteins. Acta Naturae. 2009;1(3):29–51. doi:10.32607/20758251-2009-1-3-29-51
  • Meister A, Anderson ME. Glutathione. Annu Rev Biochem. 1983;52(1):711–60. doi:10.1146/annurev.bi.52.070183.003431
  • Ghibelli L, Coppola S, Rotilio G, Lafavia E, Maresca V, Ciriolo MR. Non-oxidative loss of glutathione in apoptosis via GSH extrusion. Biochem Biophys Res Commun. 1995;216(1):313–20. doi:10.1006/bbrc.1995.2626
  • Poulose SM, Fisher DR, Larson J, Bielinski DF, Rimando AM, Carey AN, Schauss AG, Shukitt-Hale B. Anthocyanin-rich Açaí (Euterpe oleracea Mart.) fruit pulp fractions attenuate inflammatory stress signaling in mouse brain BV-2 microglial cells. J Agric Food Chem. 2012;60(4):1084–93. doi:10.1021/jf203989k

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