Inhibitory Effects of Olea europaea Leaf Extract on Mesenchymal Transition Mechanism in Glioblastoma Cells

References

• Gudinavičienė G, Pranys D, Juozaitytė E. Impact of morphology and biology on the prognosis of patiens with gliomas. Medicina. 2004;40(2):112–20.
   PubMedGoogle Scholar
• Stupp R, Hegi ME, Mason WP, van den Bent MJ, Taphoorn MJ, European Organisation for Research and Treatment of Cancer Brain Tumour and Radiation Oncology Groups; National Cancer Institute of Canada Clinical Trials Group, et al.. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol. 2009;10:459–66.:
   PubMed Web of Science ®Google Scholar
• Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJB, Belanger K, Brandes AA, Marosi C, Bogdahn U, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352(10):987–96.:doi:10.1056/NEJMoa043330
   PubMed Web of Science ®Google Scholar
• Rosell R, de Las Peñas R, Balaña C, Santarpia M, Salazar F, de Aguirre I, Reguart N, Villa S, Wei J, Ramirez JL, et al. Translational research in glioblastoma multiforme: molecular criteria for patient selection. Fut Oncol. 2008;4(2):219–28.: doi:10.2217/14796694.4.2.219
   PubMed Web of Science ®Google Scholar
• Wang Q, Lu1 W, Zhao S, Pang M, Wu X, Wu H, Hoffman RM, Yang Z, Zhang YAN. Moesin Expression Is Associated with Glioblastoma Cell Proliferation and Invasion. AR. 2017;37(5):2211–8. doi:10.21873/anticanres.11556
   Web of Science ®Google Scholar
• Jiang C, Shen F, Du J, Hu Z, Li X, Su J, Wang X, Huang X. MicroRNA-564 is downregulated in glioblastoma and inhibited proliferation and invasion of glioblastoma cells by targeting TGF-β1. Oncotarget. 2016;7(35):56200–8. 30 doi:10.18632/oncotarget.8987
   PubMedGoogle Scholar
• Breznik B, Motaln H, Vittori M, Rotter A, Lah Turnšek T. Mesenchymal stem cells differentially affect the invasion of distinct glioblastoma cell lines. Oncotarget. 2017;8(15):25482–99. 11 doi:10.18632/oncotarget.16041
   PubMedGoogle Scholar
• Liu G, Yan T, Li X, Sun J, Zhang B, Wang H, Zhu Y. Daam1 activates RhoA to regulate Wnt5a‑induced glioblastoma cell invasion. Oncol Rep. 2018;39(2):465–72. doi:10.3892/or.2017.6124
   PubMed Web of Science ®Google Scholar
• Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest. 2009;119(6):1420–8. doi:10.1172/JCI39104
   PubMed Web of Science ®Google Scholar
• Thiery JP. Epithelial–mesenchymal transitions in tumour progression. Nat Rev Cancer. 2002;2(6):442–54. doi:10.1038/nrc822
   PubMed Web of Science ®Google Scholar
• Kahlert UD, Joseph JV, Kruyt FAE. EMT- and MET-related processes in nonepithelial tumors: importance for disease progression, prognosis, and therapeutic opportunities. Mol Oncol. 2017;11(7):860–77. doi:10.1002/1878-0261.12085
   PubMed Web of Science ®Google Scholar
• Gotz M, Huttner WB. The cell biology of neurogenesis. Nat Rev Mol Cell Biol. 2005;6(10):777–88. doi:10.1038/nrm1739
   PubMed Web of Science ®Google Scholar
• Fu J, Rodova M, Nanta R, Meeker D, Van Veldhuizen PJ, Srivastava RK, Shankar S. NPV-LDE-225 (Erismodegib) inhibits epithelial mesenchymal transition and self-renewal of glioblastoma initiating cells by regulating miR-21, miR-128, and miR-200. Neuro Oncol. 2013;15(6):691–706. doi:10.1093/neuonc/not011
   PubMed Web of Science ®Google Scholar
• Gilani AH, Khan AU, Shah AJ, Connor J, Jabeen Q. Blood pressure lowering effect of olive is mediated through calcium channel blockade. Int J Food Sci Nutr. 2005;56(8):613–20. doi:10.1080/09637480500539420
   PubMed Web of Science ®Google Scholar
• Bartolí R, Fernández-Bañares F, Navarro E, Castellà E, Mañé J, Alvarez M, Pastor C, Cabré E, Gassull MA. Effect of olive oil on early and late events of colon carcinogenesis in rats: modulation of arachidonic acid metabolism and local prostaglandin E(2) synthesis. Gut. 2000;46(2):191–9. doi:10.1136/gut.46.2.191
   PubMed Web of Science ®Google Scholar
• Stark AH, Kossoy G, Zusman I, Yarden G, Madar Z. Olive oil consumption during pregnancy and lactation in rats influences mammary cancer development in female offspring. Nutr Cancer. 2003;46(1):59–65. doi:10.1207/S15327914NC4601_08
   PubMed Web of Science ®Google Scholar
• Tunca B, Tezcan G, Cecener G, Egeli U, Ak S, Malyer H, Tumen G, Bilir A. Olea europaea leaf extract alters microRNA expression in human glioblastoma cells. J Cancer Res Clin Oncol. 2012;138(11):1831–44. doi:10.1007/s00432-012-1261-8
   PubMed Web of Science ®Google Scholar
• Tezcan G, Tunca B, Demirci H, Bekar A, Taskapilioglu MO, Kocaeli H, Egeli U, Cecener G, Tolunay S, Vatan O. Olea europaea leaf extract improves the efficacy of temozolomide therapy by inducing MGMT methylation and reducing P53 expression in glioblastoma. Nutr Cancer. 2017;69(6):873–80. doi:10.1080/01635581.2017.1339810
   PubMed Web of Science ®Google Scholar
• Tezcan G, Taskapilioglu MO, Tunca B, Bekar A, Demirci H, Kocaeli H, Aksoy SA, Egeli U, Cecener G, Tolunay S. Olea europaea leaf extract and bevacizumab synergistically exhibit beneficial efficacy upon human glioblastoma cancer stem cells through reducing angiogenesis and invasion in vitro. Biomed Pharmacother. 2017;90:713–23. doi:10.1016/j.biopha.2017.04.022
   PubMed Web of Science ®Google Scholar
• Tezcan G, Tunca B, Bekar A, Budak F, Sahin S. Olea europaea leaf extract improves the treatment response of GBM stem cells by modulating miRNA expression. Am J Cancer Res. 2014;4(5):572–90. 6
   PubMed Web of Science ®Google Scholar
• Piperi C, Themistocleous MS, Papavassiliou GA, Farmaki E, Levidou G, Korkolopoulou P, Adamopoulos C, Papavassiliou AG. High incidence of MGMT and RARbeta promoter methylation in primary glioblastomas: association with histopathological characteristics, inflammatory mediators and clinical outcome. Mol Med. 2010;16(1-2):1–9. doi:10.2119/molmed.2009.00140
   PubMed Web of Science ®Google Scholar
• Craig WJ. Health-promoting properties of common herbs. Am J Clin Nutr. 1999;70:491–5.
   PubMed Web of Science ®Google Scholar
• Setzer WN, Setzer MC. Plant-derived triterpenoids as potential antineoplastic agents. MRMC. 2003;3(6):540–56. doi:10.2174/1389557033487854
   Web of Science ®Google Scholar
• Nallanthighal S, Elmaliki KM, Reliene R. Pomegranate extract alters breast cancer stem cell properties in association with inhibition of epithelial-to-mesenchymal transition. Nutr Cancer. 2017;69(7):1088–98. doi:10.1080/01635581.2017.1359318
   PubMed Web of Science ®Google Scholar
• Neil VK, Mittal S. Therapeutic potential of curcumin for the treatment of brain tumors. Oxid Med Cell Longev. 2016;2016:1–14. doi:10.1155/2016/9324085
   Web of Science ®Google Scholar
• Wang W, Mouneimne G, Sidani M, Wyckoff J, Chen X, Makris A, Goswami S, Bresnick AR, Condeelis JS. The activity status of cofilin is directly related to invasion, intravasation and metastasis of mammary tumors. J Cell Biol. 2006;173(3):395–404. ‑ doi:10.1083/jcb.200510115
   PubMed Web of Science ®Google Scholar
• Saitoh M. Epithelial-mesenchymal transition is regulated at post-transcriptional levels by transforming growth factor-β signaling during tumor progression. Cancer Sci. 2015;106(5):481–8. doi:10.1111/cas.12630
   PubMed Web of Science ®Google Scholar
• Han SP, Kim JH, Han ME, Sim HE, Kim KS, Yoon S, Baek SY, Kim BS, Oh SO. SNAI1 is involved in the proliferation and migration of glioblastoma cells. Cell Mol Neurobiol. 2011;31(3):489–96. doi:10.1007/s10571-010-9643-4
   PubMed Web of Science ®Google Scholar
• Myung JK, Choi SA, Kim SK, Wang KC, Park SH. Snail plays an oncogenic role in glioblastoma by promoting epithelial mesenchymal transition. Int J Clin Exp Pathol. 2014;7(5):1977–87. 15:
   PubMed Web of Science ®Google Scholar
• Yang MH, Wu MZ, Chiou SH, Chen PM, Chang SY, Liu CJ, Teng SC, Wu KJ. Direct regulation of TWIST by HIF-1alpha promotes metastasis. Nat Cell Biol. 2008;10(3):295–305. doi:10.1038/ncb1691
   PubMed Web of Science ®Google Scholar
• Gallardo M, Calaf G. M Curcumin and epithelial-mesenchymal transition in breast cancer cells transformed by low doses of radiation and estrogen. Int J Oncol. 2016;48(6):2534–42. doi:10.3892/ijo.2016.3477
   PubMed Web of Science ®Google Scholar
• Cheng X, Chen N, Wang W, Niu Q, Li Q, et al. Inhibitory effects of curcumin on epithelial-mesenchymal transition in human gastric cancer cells and the possible mechanism. Int J Clin Exp Med. 2018;11(7):6973–9. :
   Web of Science ®Google Scholar
• Kim GT, Lee SH, Kim YM. Torilis japonica extract, a new potential EMT suppressor agent by regulation of EGFR signaling pathways. Int J Oncol. 2014;45(4):1673–9. doi:10.3892/ijo.2014.2546
   PubMed Web of Science ®Google Scholar
• Wang H, Gu H, Feng J, Qian Y, Yang L, Jin F, Wang X, Chen J, Shi Y, Lu S, et al. Celastrus orbiculatus extract suppresses the epithelial-mesenchymal transition by mediating cytoskeleton rearrangement via inhibition of the Cofilin 1 signaling pathway in human gastric cancer. Oncol Lett. 2017;14(3):2926–32. : doi:10.3892/ol.2017.6470
   PubMed Web of Science ®Google Scholar
• Do NY, Shin HJ, Lee J. Wheatgrass extract inhibits hypoxia-inducible factor-1-mediated epithelial-mesenchymal transition in A549 cells. Nutr Res Pract. 2017;11(2):83–9. doi:10.4162/nrp.2017.11.2.83
   PubMed Web of Science ®Google Scholar
• Lin Y-C, Lin J-C, Hung C-M, Chen Y, Liu L-C, Chang T-C, Kao J-Y, Ho C-T, Way T-D. Osthole inhibits insulin-like growth factor-1-induced epithelial to mesenchymal transition via the inhibition of PI3K/Akt signaling pathway in human brain cancer cells. J Agric Food Chem. 2014;62(22):5061–71. 4 doi:10.1021/jf501047g
   PubMed Web of Science ®Google Scholar
• Hei B, Wang J, Wu G, Ouyang J, Liu RE. Verbascoside suppresses the migration and invasion of human glioblastoma cells via targeting c-Met-mediated epithelial-mesenchymal transition. Biochem Biophys Res Commun. 2019;514(4):1270–7. 5 doi:10.1016/j.bbrc.2019.05.096
   PubMed Web of Science ®Google Scholar
• Wang Z, Liu Z, Yu G, Nie X, Jia W, Liu R-e, Xu R. Paeoniflorin inhibits migration and invasion of human glioblastoma cells via suppression transforming growth factor β-induced epithelial-mesenchymal transition. Neurochem Res. 2018;43(3):760–74. doi:10.1007/s11064-018-2478-y
   PubMed Web of Science ®Google Scholar
• Wang Q, Li H, Sun Z, Dong L, Gao L, Liu C, Wang X. Kukoamine A inhibits human glioblastoma cell growth and migration through apoptosis induction and epithelial-mesenchymal transition attenuation. Sci Rep. 2016;6(1):36543. doi:10.1038/srep36543
   PubMed Web of Science ®Google Scholar