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Nutrition and Cancer Volume 73, 2021 - Issue 4
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Article

Can Serum Vitamin B12 and Folate Levels Predict HPV Penetration in Patients with ASCUS?

Nefise Nazlı Yenigula Department of Obstetrics and Gynecology, Ministry of Health Sanlıurfa Training & Research Hospital, Sanlıurfa, TurkeyCorrespondence[email protected]
,
Fatma Yazıcı Yılmazb Department of Obstetrics and Gynecology, Ministry of Health Sisli Etfal Training & Research Hospital, Istanbul, Turkey
&
Isıl Ayhanc Department of Obstetrics and Gynecology, Ministry of Health Zeynep Kamil Training & Research Hospital, Istanbul, Turkey
Pages 602-608 | Received 10 Jun 2019, Accepted 22 Jul 2020, Published online: 14 Aug 2020

References

  • Parkin DM, Bray FI, Devesa SS. Cancer burden in the year 2000. The global picture. Eur J Cancer. 2001;37:4–66. doi:10.1016/S0959-8049(01)00267-2
  • Katki HA, Schiffman M, Castle PE, Fetterman B, Poitras NE, Lorey T, Cheung LC, Raine-Bennett T, Gage JC, Kinney WK, et al. Benchmarking CIN 3+ risk as the basis for incorporating HPV and Pap cotesting into cervical screening and management guidelines. J Low Genit Tract Dis. 2013;17(5 Suppl 1):S28–S35. doi:10.1097/LGT.0b013e318285423c
  • Ferlay JF. GLOBOCAN 2000. Cancer incidence, mortality and prevalence worldwide. 2001; version 1.0. IARC cancerbase.
  • Kwas ´Niewska A, Tukendorf A, Goz ´Dzicka-Jo ´Zefiak A, SemczukSikora A, Korobowicz E. Content of folic acid and free homocysteine in blood serum of human papillomavirus-infected women with cervical dysplasia. Eur J Gynaecol Oncol. 2002;23(4):311–6.
  • Whitehead N, Reyner F, Lindenbaum J. Megaloblastic changes in the cervical epithelium. Association with oral contraceptive therapy and reversal with folic acid. JAMA. 1973;226(12):1421–4.
  • Butterworth CE. Jr, Effect of folate on cervical cancer. Synergism among risk factors. Ann N Y Acad Sci. 1992;669(1):293–9. doi:10.1111/j.1749-6632.1992.tb17108.x
  • Mason JB, Levesque T. Folate: effects on carcinogenesis and the potential for cancer chemoprevention. Oncology (Basel). 1996;10:1727–42.
  • Carter JJ, Koutsky LA, Hughes JP, Lee SK, Kuypers J, Kiviat N, Galloway DA. Comparison of human papillomavirus types 16, 18, and 6 capsid antibody responses following incident infection. J Infect Dis. 2000;181(6):1911–9. doi:10.1086/315498
  • Bosch FX, Lorincz A, Muñoz N, Meijer CJLM, Shah KV. The causal relation between human papillomavirus and cervical cancer. J Clin Pathol. 2002;55(4):244–65. doi:10.1136/jcp.55.4.244
  • Chew GK, Cruickshank ME, Rooney PH, Miller ID, Parkin DE, Murray GI. Human papillomavirus 16 infection in adenocarcinoma of the cervix. Br J Cancer. 2005;93(11):1301–4. doi:10.1038/sj.bjc.6602855
  • IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Meeting, World Health Organization, International Agency for Research on Cancer. 2007. Human papillomaviruses. Vol. 90. World Health Organization.
  • Chandra S, Chandra RK. Nutrition, immuneresponse, and outcome. Prog Food Nutr Sci. 1986;10(5):1–65.
  • Dhur A, Galan P, Hercberg S. Folate status and the immune system. Prog Food Nutr Sci. 1991;15(1-2):43–60.
  • Maggini S, Wintergerst ES, Beveridge S, Hornig DH. Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses. Br J Nutr. 2007;98(S1):S29–S35. doi:10.1017/S0007114507832971
  • Popescu NC, DiPaolo JA, Amsbaugh SC. Integration sites of human papillomavirus 18 DNA sequences on HeLa cell chromosomes. Cytogenet Cell Genet. 1987;44(1):58–62. doi:10.1159/000132342
  • Fenech M. Nutrition and genome health. In Nutrigenomics-opportunities in Asia. Vol. 60; 2007. p. 49–65.
  • Piyathilake CJ, Macaluso M, Chambers MM, Badiga S, Siddiqui NR, Bell WC, Edberg JC, Partridge EE, Alvarez RD, Johanning GL, et al. Folate and vitamin B12 may play a critical role in lowering the HPV 16 methylation–associated risk of developing higher grades of CIN. Cancer Prev Res. 2014;7(11):1128–37. doi:10.1158/1940-6207.CAPR-14-0143
  • Piyathilake CJ, Henao OL, Meleth S, Partridge E, Heimburger D. Folate is associated with the acquisition, persistence and clearance of high-risk (HR) human papillomavirus (HPV). FASEB J. 2003;17(4):373.
  • Piyathilake CJ, Badiga S, Paul P, Vijayaraghavan K, Vedantham H, Sudula M, Sowjanya P, Ramakrishna G, Shah KV, Partridge EE, et al. Indian women with higher serum concentrations of folate and vitamin B12 are significantly less likely to be infected with carcinogenic or high-risk (HR) types of human papillomaviruses (HPVs). Int J Women's Health. 2010;2:7.
  • Abike F, Engin AB, Dunder İ, Tapisiz OL, Aslan C, Kutluay L. Human papilloma virus persistence and neopterin, folate and homocysteine levels in cervical dysplasias. Arch Gynecol Obstet. 2011;284(1):209–14. doi:10.1007/s00404-010-1650-7

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