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Article

Cytotoxic Activity and Initiation of Apoptosis via Intrinsic Pathway in Jurkat Cells by Leaf Extract of Zanthoxylum rhetsa DC

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Pages 1768-1779 | Received 09 Jan 2020, Accepted 02 Aug 2020, Published online: 18 Aug 2020

References

  • Leukemia Immunotherapy - Cancer Research Institute [Internet]. [cited 2019 Mar 27]. Available from: https://www.cancerresearch.org/immunotherapy/cancer-types/leukemia.
  • Lucas DM, Still PC, Pérez LB, Grever MR, Kinghorn AD. Potential of plant-derived natural products in the treatment of leukemia and lymphoma. Curr Drug Targets. 2010;11(7):812–822. doi:10.2174/138945010791320809
  • Anonymous. The wealth of India: raw materials and industrial products. Vol. XI. New Delhi: Publication and Information Directorate, CSIR; 1956. pp. 22–23.
  • Quattrocchi U. CRC world dictionary of medicinal and poisonous plants: common names, scientific names, eponyms, synonyms, and etymology. New Delhi: CRC Press; 2012. p. 3650.
  • Patiño LO, Prieto RJ, Cuca SL. Zanthoxylum genus as a potential source of bioactive compounds. In: Iraj R, editor. Bioactive compounds in phytomedicine. Intech Open; 2012. p.189-218, doi:10.5772/26037.
  • Anwarul I, Abu S, Md Anwar UI, Astaq GRMMK, Helal UB, Shah AB. A flavonone from leaves of Zanthoxylum budrunga: its in vitro antimicrobial activity and cytotoxic evaluation. J Med Sci. 2001;1(4):209–213. doi:10.3923/jms.2001.209.213
  • Yadav AK, Tangpu V. Therapeutic efficacy of Zanthoxylum rhetsa DC extract against experimental Hymenolepis diminuta (Cestoda) infections in rats. J Parasit Dis. 2009;33(1–2):42–47. doi:10.1007/s12639-009-0007-2
  • Shaik G, Sujatha N, Mehar SK. Medicinal plants as a source of antibacterial agents to counter Klebsiella pneumoniae. J Appl Pharm Sci. 2014;4:135–147.
  • Azad AK, Ohidul I, Rima E, Mohaiminul I, Chand S, Jeb-Un N, Firoj A. Phytochemical screening and in-vitro thrombolytic activity of methanolic leaf extract of Zanthoxylum rhetsa. J Pharm Sci Res. 2015;7:302–304.
  • Perala K, Ciddi V. Simultaneous quantitative determination of nitidine, chelerythrine and sanguinarine using HPTLC from callus extract of Zanthoxylum rhetsa. Am J Anal Chem. 2018;9(8):386–396. doi:10.4236/ajac.2018.98030
  • Rana K, Arora A, Bansal S, Chawla R. Synthesis, in vitro anticancer and antimicrobial evaluation of novel substituted dihydropyrimidines. Ind J Pharm Sci. 2014;76:339.
  • Chang H-Y, Huang H-C, Huang T-C, Yang P-C, Wang Y-C, Juan H-F. Flow cytometric detection of reactive oxygen species. Bio-Protocol. 2013;3(8):e431. doi:10.21769/BioProtoc.431
  • Kwan YP, Saito T, Ibrahim D, Al-Hassan FMS, Ein Oon C, Chen Y, Jothy SL, Kanwar JR, Sasidharan S. Evaluation of the cytotoxicity, cell-cycle arrest, and apoptotic induction by Euphorbia hirta in MCF-7 breast cancer cells. Pharm Biol. 2013;54:1–14.
  • Katiyar SK, Roy AM, Baliga MS. Silymarin induces apoptosis primarily through a p53-dependent pathway involving Bcl-2/Bax, cytochrome c release, and caspase activation. Mol Cancer Ther. 2005;4(2):207–216.
  • Madhumitha G, Fowsiya JA. Hand book on: semi micro technique for extraction of alkaloids. Indore: International E-Publication; 2015. p. 9.
  • Finucane DM, Bossy-Wetzel E, Waterhouse NJ, Cotter TG, Green DR. Bax-induced caspase activation and apoptosis via cytochrome c release from mitochondria is inhabitable by Bcl-xL. J Biol Chem. 1999;274(4):2225–2233. doi:10.1074/jbc.274.4.2225
  • Manosroi A, Akazawa H, Pattamapun K, Kitdamrongtham W, Akihisa T, Manosroi W, Manosroi J. Potent anti-proliferative effects against oral and cervical cancers of Thai medicinal plants selected from the Thai/Lanna medicinal plant recipe database “MANOSROI III”. Pharm Biol. 2015;53(7):1075–1081. doi:10.3109/13880209.2014.959613
  • Caxito MLC, Correia RR, Gomes ACC, Justo G, Coelho MGP, Sakuragui CM, Kuster RM, Sabino KCC. In vitro antileukemic activity of Xanthosoma sagittifolium (Taioba) leaf extract. Evid Based Compl Alternat Med. 2015;2015:384267. doi:10.1155/2015/384267
  • Martins LM, Mesner PW, Kottke TJ, Basi GS, Sinha S, Tung JS, Svingen PA, Madden BJ, Takahashi A, McCormick DJ, et al. Comparison of caspase activation and subcellular localization in HL-60 and K562 cells undergoing etoposide-induced apoptosis. Blood. 1997;90(11):4283–4296. doi:10.1182/blood.V90.11.4283.4283_4283_4296
  • Lee JI, Kim I-H, Nam T-J. Crude extract and solvent fractions of Calystegia soldanella induce G1 and S phase arrest of the cell cycle in HepG2 cells. Int J Oncol. 2017;50(2):414–420. doi:10.3892/ijo.2017.3836
  • Qiaohong Q, Wanqing C, Yajuan C. Targeting reactive oxygen species in cancer via Chinese herbal medicine. Oxid Med Cell Longev. 2019;2019:9240426.
  • Shahali A, Ghanadian M, Jafari SM, Aghaei M. Mitochondrial and caspase pathways are involved in the induction of apoptosis by nardosinen in MCF-7 breast cancer cell line. Res Pharm Sci. 2018;13(1):12–21. doi:10.4103/1735-5362.220963
  • Samudio I, Konopleva M, Carter B, Andreeff M. Apoptosis in leukemias: regulation and therapeutic targeting. Cancer Treat Res. 2010;145:197–217. doi:10.1007/978-0-387-69259-3_12
  • Perini GF, Ribeiro GN, Pinto Neto JV, Campos LT, Hamerschlak N. BCL-2 as therapeutic target for hematological malignancies. J Hematol Oncol. 2011;11:65.
  • Cai J, Yang J, Jones D. Mitochondrial control of apoptosis: the role of cytochrome c. Biochim Biophys Acta. 1998;1366(1–2):139–149. doi:10.1016/S0005-2728(98)00109-1
  • Kitazumi I, Tsukahara M. Regulation of DNA fragmentation: the role of caspases and phosphorylation. FEBS J. 2011;278(3):427–441. doi:10.1111/j.1742-4658.2010.07975.x
  • Olivero AM, Maldonado RW, Olivero VJ. Natural products as chemopreventive agents by potential inhibition of the kinase domain in ErbB receptors. Molecules. 2017;22:308.
  • Sun H, Hou H, Lu P, Zhang L, Zhao F, Ge C, Wang T, Yao M, Li J. Isocorydine inhibits cell proliferation in hepatocellular carcinoma cell lines by inducing G2/M cell cycle arrest and apoptosis. PLoS One. 2012;7(5):e36808. doi:10.1371/journal.pone.0036808
  • Jeong M, Kim H, Lee J, Choi J-H, Jang D. (−)-Asarinin from the roots of Asarum sieboldii induces apoptotic cell death via caspase activation in human ovarian cancer cells. Molecules. 2018;23(8):1849. doi:10.3390/molecules23081849

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