References
- Jilkova ZM, Kurma K, Decaens T. Animal models of hepatocellular carcinoma: the role of immune system and tumor microenvironment. Cancers (Basel). 2019;11(10):1487. doi:https://doi.org/10.3390/cancers11101487
- Zhang QY, Wang FX, Jia KK, Kong LD. Natural product interventions for chemotherapy and radiotherapy-induced side effects. Front Pharmacol. 2018;9:1253.
- Wan MLY, El-Nezami H. Targeting gut microbiota in hepatocellular carcinoma: probiotics as a novel therapy. Hepatobiliary Surg Nutr. 2018;7(1):11–20. doi:https://doi.org/10.21037/hbsn.2017.12.07
- El-Deeb NM, Yassi AM, Al-Madboly LA, El-Hawiet A. A novel purified Lactobacillus acidophilus 20079 exopolysaccharide, LA-EPS-20079, molecularly regulates both apoptotic and NF-κB infammatory pathways in human colon cancer. Microb Cell Fact. 2018;17(1):194. doi:https://doi.org/10.1186/s12934-018-0877-z
- Moshiri M, Dallal MMS, Rezaei F, Douraghi M, Sharifi L, Noroozbabaei Z, Gholami M, Mirshafiey A. The effect of Lactobacillus acidophilus PTCC 1643 on cultured intestinal epithelial cells infected with Salmonella enterica Serovar enteritidis. Osong Public Health Res Perspect. 2017;8(1):54–60. doi:https://doi.org/10.24171/j.phrp.2017.8.1.07
- Seo BJ, Bajpai VK, Rather IA, Park YH. Partially purified exopolysaccharide from Lactobacillus plantarum YML009 with total phenolic content, antioxidant and Free radical scavenging efficacy. IJPER. 2015;49(4):282–92. doi:https://doi.org/10.5530/ijper.49.4.6
- Li J, Sung CYJ, Lee N, Ni Y, Pihlajamäki J, Panagiotou G, El-Nezami H. Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in mice. Proc Natl Acad USA. 2016;113(9):E1306–15.
- Jiang Y, Han QJ, Zhang J. Hepatocellular carcinoma: mechanisms of progression and immunotherapy. World J Gastroenterol. 2019;25(25):3151–67. doi:https://doi.org/10.3748/wjg.v25.i25.3151
- Abdallah HMI, Abdel-Rahman RF, El Awdan SA, Allam RM, El-Mosallamy AEMK, Selim MS, Mohamed SS, Arbid MS, Farrag AH. Protective effect of some natural products against chemotherapy-induced toxicity in rats. Heliyon. 2019;5(5):e01590. doi:https://doi.org/10.1016/j.heliyon.2019.e01590
- Sun X, Zhang J, Wang L, Tian Z. Growth inhibition of human hepatocellular carcinoma cells by blocking STAT3 activation with decoy-ODN. Cancer Lett. 2008;262(2):201–13. doi:https://doi.org/10.1016/j.canlet.2007.12.009
- Soni S, Anand P, Padwad YS. MAPKAPK2: the master regulator of RNA binding proteins modulates transcript stability and tumor progression. J Exp Clin Cancer Res. 2019;38(1):18. doi:https://doi.org/10.1186/s13046-019-1115-1
- Yang J, Li M, Zheng QC. Emerging role of toll-like receptor 4 in hepatocellular carcinoma. J Hepatocell Carcinoma. 2015;2:11–7.
- Aachary AA, Gobinath D, Srinivasan K, Prapulla SG. Protective effect of xylooligosaccharides from corncob on 1, 2-dimethylhydrazine induced colon cancer in rats. Bioactive Carbohydrates Dietary Fibers. 2015;5(2):146–52. doi:https://doi.org/10.1016/j.bcdf.2015.03.004
- Zahran WE, Elsonbatyb SM, Moawed FSM. Lactobacillus rhamnosus ATCC 7469 exopolysaccharides synergizes with low level ionizing radiation to modulate signaling molecular targets in colorectal carcinogenesis in rats. Biomed Pharmacother. 2017;92:384–93. doi:https://doi.org/10.1016/j.biopha.2017.05.089
- Frey B, Hehlgans S, Rodel F, Gaipl US. Modulation of inflammation by low and high doses of ionizing radiation: implications for benign and malign diseases. Cancer Lett. 2015;368(2):230–7. doi:https://doi.org/10.1016/j.canlet.2015.04.010
- Darwish HA, El-Boghdady NA. Possible involvement of oxidative stress in diethylnitrosamine-induced hepatocarcinogenesis: chemopreventive effect of curcumin. J Food Bioch. 2013;37(3):353–61. doi:https://doi.org/10.1111/j.1745-4514.2011.00637.x
- Reitman S, Frankel S. A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Am J Clin Path. 1957;28:56–63. doi:https://doi.org/10.1093/ajcp/28.1.56
- Gornall G, Bardawill C, David M. Determination of serum proteins by means of the biuret reaction. J. Biol. Chem. 1949;177:751–66.
- Szasz G. Reaction-rate method for gamma-glutamyltransferase activity in serum. Clin Chem. 1976;22:2051. doi:https://doi.org/10.1093/clinchem/22.12.2051
- Beutler E, Duron O, Kelly BM. Improved method for the determination of blood glutathione. J Lab Clin Med. 1963;61:882–8.
- Yoshioka TK, Kawada T, Shimada T, Mori M. Lipid peroxidation in maternal and cord blood and protective mechanism against activated-oxygen toxicity in the blood. Am J Obstet Gynecol. 1979;135:372–6. doi:https://doi.org/10.1016/0002-9378(79)90708-7
- Chomczynski P. A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. Biotechniques. 1993;15:532–7.
- Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72(1–2):248–54. doi:https://doi.org/10.1016/0003-ss2697(76)90527-3
- Hubert FX, Voisine C, Louvet C, Heslan JM, Ouabed A, Heslan M, Josien R. Differential pattern recognition receptor expression but stereotyped responsiveness in rat spleen dendritic cell subsets. J Immunol. 2006;177:1007–16. doi:https://doi.org/10.4049/jimmunol.177.2.1007
- Pfaffl WW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001;29:2002–7.
- Banchroft JD, Stevens A, Turner DR. Theory and practice of histological techniques. 4th ed. New York, London, San Francisco, Tokyo: Churchil Livingstone, 1996. p. 125.
- Du B, Yang YD, Bian ZX, Xu BJ. Characterization and anti-inflammatory potential of an exopolysaccharide from submerged mycelial culture of Schizophyllum commune. Front Pharmacol. 2017;8:1–11.
- Dinić M, Pecikoza U, Djokić J, Stepanović-Petrović R, Milenković M, Stevanović M, Filipović N, Begović J, Golić N, Lukić J. Exopolysaccharide produced by probiotic strain Lactobacillus paraplantarum BGCG11 reduces inflammatory hyperalgesia in rats. Front Pharmacol. 2018;9:1–12.
- Palaniyandi SA, Damodharan K, Suh JW, Yang SH. Functional characterization of an exopolysaccharide produced by Bacillus sonorensis MJM60135 isolated from ganjang. J Microbiol Biotechnol. 2018;28(5):663–70. doi:https://doi.org/10.4014/jmb.1711.11040
- Dara KK, Alib S, Ejazc M, Nasreenc S, Ashrafc N, Gillanic SF, Shafic N, Safeerc S, Khanc MA, Andleebc S, et al. In vivo induction of hepatocellular carcinoma by diethylnitrosoamine and pharmacological intervention in Balb C mice using Bergenia ciliata extracts. Braz J Biol. 2019;79(4):629–38. doi:https://doi.org/10.1590/1519-6984.186565
- Anoopraj R, Hemalatha S, Balachandran C. A preliminary study on serum liver function indices of diethylnitrosamine induced hepatocarcinogenesis and chemoprotective potential of in male Wistar rats. Vet World. 2014;7(6):439–42. doi:https://doi.org/10.14202/vetworld.2014.439-442
- Senoner T, Schindler S, Stättner S, Öfner D, Troppmair J, Primavesi F. Associations of oxidative stress and postoperative outcome in liver surgery with an outlook to future potential therapeutic options. Oxid Med Cell. 2019;2019:1–18. doi:https://doi.org/10.1155/2019/3950818
- Mahfouz MK, Abd El-Hamid OM, Emam MA, Bakr MA. Biochemical and histopathological effect of probiotics on experimentally induced liver fibrosis in rat. BVMJ. 2016;31(2):248–53. doi:https://doi.org/10.21608/bvmj.2016.31306
- Selim MS, Mohamed SS, Asker MM, Salama AAA, Abdallah HMI, Yassen NN. Production and characterization of exopolysaccharide from marine Bacillus sp. MSHN2016 with studying its effect on isoniazid/rifampicin-induced hepatic and renal toxicities in rats. J Appl Pharm Sci. 2018;8(8):1–11.
- Unsal V, Belge-Kurutaş E. Experimental hepatic carcinogenesis: oxidative stress and natural antioxidants. J Med Sci. 2017;5(5):686–91.
- Gu FM, Li QL, Gao Q, Jiang JH, Zhu K, Huang XY, Pan JF, Yan J, Hu JH, Wang Z, Dai Z, et al. IL-17 induces AKT-dependent IL-6/JAK2/STAT3 activation and tumor progression in hepatocellular carcinoma. Mol Can. 2011;10:150. doi:https://doi.org/10.1186/1476-4598-10-150
- Kleniewska p, Pawliczak R. Influence of synbiotics on selected oxidative stress parameters. Oxid Med Cell Longev. 2017;2017:1–8. doi:https://doi.org/10.1155/2017/9315375
- Song X, Liu Z, Zhang J, Yang Q, Ren Z, Zhang C, Liu M, Gao Z, Zhao H, Jia L. Anti-inflammatory and hepatoprotective effects of exopolysaccharides isolated from Pleurotus geesteranus on alcohol induced liver injury. Sci Rep. 2018;8:1–13.
- Alqahtani A, Khan Z, Alloghbi A, Ahmed TSS, Ashraf M, Hammouda DM. Hepatocellular carcinoma: molecular mechanisms and targeted therapies. Medicina. 2019;55(9):526. doi:https://doi.org/10.3390/medicina55090526
- Paquissi FC. Immunity and fibrogenesis: the Role of Th17/IL-17 axis in HBV and HCV-induced chronic hepatitis and progression to cirrhosis. Front Immunol. 2017;8:1–16. doi:https://doi.org/10.3389/fimmu.2017.01195
- Zhang Y, Li A, Sun Y, Du P, Liu L, Li S, Zhang C. Lactobacillus acidophilus regulates STAT3 and STAT5 signaling in bovine β-lg-sensitized mice model. Dairy Sci Technol. 2016;96(4):501–12. doi:https://doi.org/10.1007/s13594-016-0284-3
- Jiang Y, Lü X, Man C, Han L, Shan Y, Qu X, Liu Y, Yang S, Xue Y, Zhang Y. Lactobacillus acidophilus induces cytokine and chemokine production via NF-kB and p38 mitogen-activated protein kinase signaling pathways in intestinal epithelial cells. Clin Vaccine Immunol. 2012;19(4):603–8. doi:https://doi.org/10.1128/CVI.05617-11
- Elsonbaty SM, Zahran WE, Moawed FSM. Gamma-irradiated β-glucan modulates signaling molecular targets of hepatocellular carcinoma in rats. Tumor Biol. 2017;2017:1–10.
- Wang M, Zhang XJ, Feng R, Jiang Y, Zhang DY, He C, Li P, Wan P. Hepatoprotective properties of Penthorum chinense pursh against carbon tetrachloride-induced acute liver injury in mice. Chinese Med. 2017;12:32–42.