References
- Styczyński J, Tridello G, Koster L, Iacobelli S, van Biezen A, van der Werf S, Mikulska M, Gil L, Cordonnier C, Ljungman P, et al. Death after hematopoietic stem cell transplantation: changes over calendar year time, infections and associated factors. Bone Marrow Transplant. 2020;55(1):126–136. doi:https://doi.org/10.1038/s41409-019-0624-z
- Majhail NS. Long-term complications after hematopoietic cell transplantation. Hematol Oncol Stem Cell Ther. 2017;10(4):220–227. doi:https://doi.org/10.1016/j.hemonc.2017.05.009
- Lazarow H, Singer R, Compher C, Gilmar C, Kucharczuk CR, Mangan P, Salam K, Cunningham K, Stadtmauer EA, Landsburg DJ. Effect of malnutrition-driven nutritional support protocol on clinical outcomes in autologous stem cell transplantation patients. Support Care Cancer. 2021;29(2):997–1003. doi:https://doi.org/10.1007/s00520-020-05571-1
- Morishita S, Kaida K, Tanaka T, Itani Y, Ikegame K, Okada M, Ishii S, Kodama N, Ogawa H, Domen K. Prevalence of sarcopenia and relevance of body composition, physiological function, fatigue, and health-related quality of life in patients before allogeneic hematopoietic stem transplantation. Support Care Cancer. 2012;20 (12):3161–3168. doi:https://doi.org/10.1007/s00520-012-1460-5
- Ando T, Fujisawa S, Sakuma T, Teshigawara H, Matsumura A, Suzuki T. Value of computed tomography-defined sarcopenia: a prognostic predictor of non-relapse mortality following allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia and myelodysplastic syndrome. Blood. 2017;130(1):4562.
- Tanaka S, Imataki O, Kitaoka A, Fujioka S, Hanabusa E, Ohbayashi Y, Uemura M, Arima N, Yamamoto T. Clinical impact of sarcopenia and relevance of nutritional intake in patients before and after allogeneic hematopoietic stem cell transplantation. J Cancer Res Clin Oncol. 2017;143(6):1083–1092. doi:https://doi.org/10.1007/s00432-016-2336-8
- Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, Cooper C, Landi F, Rolland Y, Sayer AA, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(1):16–31. doi:https://doi.org/10.1093/ageing/afy169
- Mijnarends DM, Koster A, Schols J, Meijers JMM, Halfens R, Gudnason V, Eiriksdottir G, Siggeirsdottir K, Sigurdsson S, Jonsson PV, et al. Physical activity and incidence of sarcopenia: the population-based AGES-Reykjavik Study. Age Ageing. 2016;45(5):614–620. doi:https://doi.org/10.1093/ageing/afw090
- Lim JU, Lee JH, Kim JS, Hwang Y, II, Kim TH, Lim SY, Yoo KH, Jung K-S, Kim YK, Rhee CK. Comparison of World Health Organization and Asia-Pacific body mass index classifications in COPD patients. Int J Chron Obstruct Pulmon Dis. 2017;12:2465–2475. doi:https://doi.org/10.2147/COPD.S141295
- World Health Organization. Body Mass Index – BMI. Copenhagen: WHO, Regional Office for Europe; 2021. [accessed 2021 Mar 1]. https://www.euro.who.int/en/health-topics/disease-prevention/nutrition/a-healthy-lifestyle/body-mass-index-bmi.
- Dietrich S, Radujkovic A, Stölzel F, Falk CS, Benner A, Schaich M, Bornhäuser M, Ehninger G, Krämer A, Hegenbart U, et al. Pretransplant metabolic distress predicts relapse of acute myeloid leukemia after allogeneic stem cell transplantation. Transplantation. 2015;99(5):1065–1071. doi:https://doi.org/10.1097/TP.0000000000000471
- Carson KR, Bates ML, Tomasson MH. The skinny on obesity and plasma cell myeloma: a review of the literature. Bone Marrow Transplant. 2014;49(8):1009–1015. doi:https://doi.org/10.1038/bmt.2014.71
- Tarella C, Caracciolo D, Gavarotti P, Argentino C, Zallio F, Corradini P, Novero D, Magnani C, Pileri A, Basingstoke A, et al. Overweight as an adverse prognostic factor for on-Hodgkin’s lymphoma patients receiving high-dose chemotherapy and autograft. Bone Marrow Transplant. 2000;26(11):1185–1191. doi:https://doi.org/10.1038/sj.bmt.1702692
- Navarro WH, Loberiza FR, Bajorunaite R, van Besien K, Vose JM, Lazarus HM, Rizzo JD. Effect of body mass index on mortality of patients with lymphoma undergoing autologous hematopoietic cell transplantation. Biol Blood Marrow Transplant. 2006;12(5):541–551. doi:https://doi.org/10.1016/j.bbmt.2005.12.033
- Calle EE, Kaaks R. Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat Rev Cancer. 2004;4(8):579–591. doi:https://doi.org/10.1038/nrc1408
- Yang H, Youm Y, Vandanmagsar B, Ravussin A, Gimble JM, Greenway F, Stephens JM, Mynatt RL, Dixit VD. Obesity increases the production of proinflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: implications for systemic inflammation and insulin resistance. J Immunol. 2010;185(3):1836–1845. doi:https://doi.org/10.4049/jimmunol.1000021
- Arends J, Bachmann P, Baracos V, Barthelemy N, Bertz H, Bozzetti F, Fearon K, Hütterer E, Isenring E, Kaasa S, et al. ESPEN guidelines on nutrition in cancer patients. Clin Nutr. 2017;36(1):11–48. doi:https://doi.org/10.1016/j.clnu.2016.07.015
- Hirose EY, de Molla VC, Gonçalves MV, Pereira AD, Szor RS, da Fonseca ARBM, Fatobene G, Serpa MG, Xavier EM, Tucunduva L, et al. The impact of pretransplant malnutrition on allogeneic hematopoietic stem cell transplantation outcomes. Clin Nutr Espen. 2019;33:213–219. doi:https://doi.org/10.1016/j.clnesp.2019.05.005
- Fuji S, Mori T, Khattry N, Cheng J, Do YR, Yakushijin K, Kohashi S, Fukuda T, Kim S-W. Severe weight loss in 3 months after allogeneic hematopoietic SCT was associated with an increased risk of subsequent non-relapse mortality. Bone Marrow Transplant. 2015;50(1):100–105. doi:https://doi.org/10.1038/bmt.2014.228
- Be the Match, National Marrow Donor Program. Transplant basics. BTM. [accessed 2021 Feb 10]. https://bethematch.org/transplant-basics/.
- Henig I, Zuckerman T. Hematopoietic stem cell transplantation-50 years of evolution and future perspectives. Rambam Maimonides Med J. 2014;5(4):e0028 doi:https://doi.org/10.5041/RMMJ.10162
- Bone Marrow Transplant Risks and Survival Rate. MedicineNet. [accessed 2021 March 11]. https://www.medicinenet.com/bone_marrow_transplant_risks_survival_prognosis/article.htm#how_long_can_you_live_after_a_bone_marrow_transplant.
- National Cancer Institute. NCI dictionary of cancer terms. Rockville, MD: National Cancer Institute. [accessed 2021 Feb 27]. https://www.cancer.gov/publications/dictionaries/cancer-terms.
- PRISMA Flow Diagram. PRISMA, Transparent reporting of systematic reviews and meta-analyses; 2015. [accessed 2021 Feb 10]. http://prisma-statement.org/.
- Doney K, McMillen K, Buono L, Deeg HJ, Gooley T. Impact of body mass index on outcomes of hematopoietic stem cell transplantation in adults. Biol Blood Marrow Transplant. 2019;25(3):613–620. doi:https://doi.org/10.1016/j.bbmt.2018.10.006
- Jaime-Pérez JC, Colunga-Pedraza PR, Gutiérrez-Gurrola B, Brito-Ramírez AS, Gutíerrez-Aguirre H, Cantú-Rodríguez OG, Herrera-Garza JL, Gómer-Almaguer D. Obesity is associated with higher overall survival in patients undergoing an outpatient reduced-intensity conditioning hematopoietic stem cell transplant. Blood Cells Mol Dis. 2013;51(1):61–65. doi:https://doi.org/10.1016/j.bcmd.2013.01.010
- Voshtina E, Szabo A, Hamadani M, Fenske TS, D’Souza A, Chhabra S, Saber W, Drobyski WR, Hari P, Shah NN. Impact of obesity on clinical outcomes of elderly patients undergoing allogeneic hematopoietic cell transplantation for myeloid malignancies. Biol Blood Marrow Transplant. 2019;25(1):e33–e38. doi:https://doi.org/10.1016/j.bbmt.2018.08.031
- DeFilipp Z, Troschel FM, Qualls DA, Li S, Kuklinski MW, Kempner ME, Hochberg E, Chen Y, El-Jawahri A, Fintelmann FJ. Evolution of body composition following autologous and allogeneic hematopoietic cell transplantation: incidence of sarcopenia and association with clinical outcomes. Biol Blood Marrow Transplant. 2018;24(8):1741–1747. doi:https://doi.org/10.1016/j.bbmt.2018.02.016
- Scheich S, Enßle JC, Mücke VT, Acker F, Aspacher L, Wolf S, Wilke AC, Weber S, Brunnberg U, Serve H, et al. Obesity is associated with an impaired survival in lymphoma patients undergoing autologous stem cell transplantation. PLoS One. 2019;14(11):e0225035. doi:https://doi.org/10.1371/journal.pone.0225035
- Yang J, Xue S-L, Zhang X, Zhou Y-N, Qin L-Q, Shen Y-P, Wu D-P. Effect of body mass index on overall survival of patients with allogeneic hematopoietic stem cell transplantation. Eur J Clin Nutr. 2017;71(6):750–754. doi:https://doi.org/10.1038/ejcn.2016.225
- Armenian SH, Xiao M, Berano Teh J, Lee B, Chang HA, Mascarenhas K, Lee S, Iukuridze A, Xie JJ, Scott JM, et al. Impact of sarcopenia on adverse outcomes after allogeneic hematopoietic cell transplantation. J Natl Cancer Inst. 2019;111(8):837–844. doi:https://doi.org/10.1093/jnci/djy231
- Khouri J, Rybicki L, Majhail NS, Kalaycio M, Pohlman B, Hill B, Jagadeesh D, Dean R, Hamilton B, Sobecks R, et al. Body mass index does not impact hematopoietic progenitor cell mobilization for autologous hematopoietic cell transplantation. J Clin Apher. 2019;34(6):638–645. doi:https://doi.org/10.1002/jca.21739
- Sakatoku K, Ito A, Tajima K, Yamaguchi K, Kuno M, Aoki N, Tanaka T, Kurosawa S, Inamoto Y, Kim S-W, et al. Prognostic significance of low pre-transplant skeletal muscle mass on survival outcomes in patients undergoing hematopoietic stem cell transplantation. Int J Hematol. 2020;111(2):267–277. doi:https://doi.org/10.1007/s12185-019-02773-0
- Radujkovic A, Becker N, Benner A, Penack O, Platzbecker U, Stölzel F, Bornhauser M, Hegenbart U, Ho AD, Dreger P, et al. Pre-transplant weight loss predicts inferior outcome after allogeneic stem cell transplantation in patients with myelodysplastic syndrome. Oncotarget. 2015;6(33):35095–35106. doi:https://doi.org/10.18632/oncotarget.4805
- Fuji S, Takano K, Mori T, Eto T, Taniguchi S, Ohashi K, Sakamaki H, Morishima Y, Kato K, Miyamura K, et al. Impact of pretransplant body mass index on the clinical outcome after allogeneic hematopoietic SCT. Bone Marrow Transplant. 2014;49(12):1505–1512. doi:https://doi.org/10.1038/bmt.2014.178
- Pereira AZ, de Almeida-Pitito B, Eugenio GC, Ruscitto do Prado R, Silva CC, Hamerschlak N. Impact of obesity and visceral fat on mortality in Hematopoietic Stem Cell Transplantation (HSCT). JPEN J Parenter Enteral Nutr. 2021;45(7):1597–1603. doi:https://doi.org/10.1002/jpen.2048
- Urbain P, Birlinger J, Ihorst G, Biesalski H-K, Finke J, Bertz H. Body mass index and bioelectrical impedance phase angle as potentially modifiable nutritional markers are independent risk factors for outcome in allogeneic hematopoietic cell transplantation. Ann Hematol. 2013;92(1):111–119. doi:https://doi.org/10.1007/s00277-012-1573-4
- Caram MV, Bellile EL, Englesbe MJ, Terjimanian M, Wang SC, Griggs JJ, Couriel D. Sarcopenia is associated with autologous transplant-related outcomes in patients with lymphoma. Leuk Lymphoma. 2015;56(10):2855–2862. doi:https://doi.org/10.3109/10428194.2015.1014359
- Rieger CT, Wischumerski I, Rust C, Fiegl M. Weight loss and decrease of body mass index during allogeneic stem cell transplantation are common events with limited clinical impact. PLoS One. 2015;10(12):e0145445 doi:https://doi.org/10.1371/journal.pone.0145445
- Psoas Syndrome. Cleveland clinic; 2021. [accessed 2021 February 27]. https://my.clevelandclinic.org/health/diseases/15721-psoas-syndrome.
- Singh N, Loren AW. Overview of hematopoietic cell transplantation for the treatment of hematologic malignancies. Clin Chest Med. 2017;38(4):575–593. doi:https://doi.org/10.1016/j.ccm.2017.07.001
- Ramachandran V, Kolli SS, Strowd LC. Review of graft-versus-host disease. Dermatol Clin. 2019;37(4):569–582. doi:https://doi.org/10.1016/j.det.2019.05.014
- Gao Y, Ma J. Tacrolimus in adult hematopoietic stem cell transplantation. Expert Opin Drug Metab Toxicol. 2019;15(10):803–811. doi:https://doi.org/10.1080/17425255.2019.1675635
- Nuttall FQ. Body mass index: obesity, BMI, and health: a critical review. Nutr Today. 2015;50(3):117–128. doi:https://doi.org/10.1097/NT.0000000000000092
- Chughtai K, Song Y, Zhang P, Derstine B, Gatza E, Friedman J, Hully L, Inglis C, Goldstein S, Magenau J, et al. Analytic morphomics: a novel CT imaging approach to quantify adipose tissue and muscle composition in allogeneic hematopoietic cell transplantation. Bone Marrow Transplant. 2016;51(3):446–450. doi:https://doi.org/10.1038/bmt.2015.267
- Kyle UG, Chalandon Y, Miralbell R, Karsegard VL, Hans D, Trombetti A, Rizzoli R, Helg C, Pichard C. Longitudinal follow-up of body composition in hematopoietic stem cell transplant patients. Bone Marrow Transplant. 2005;35(12):1171–1177. doi:https://doi.org/10.1038/sj.bmt.1704996
- Chu MP, Lieffers J, Ghosh S, Belch AR, Chua NS, Fontaine A, Sangha R, Turner AR, Baracos VE, Sawyer MB, et al. Skeletal muscle radio-density is an independent predictor of response and outcomes in follicular lymphoma treated with chemoimmunotherapy. PloS One. 2015;10(6):e0127589. doi:https://doi.org/10.1371/journal.pone.0127589
- American Cancer Society. Cancer statistics center. [accessed 2021 Feb 21]. http://cancerstatisticscenter.cancer.org/?_ga=2.84520208.844054865.1613951983-654552607.1613951983#. !/.
- World Health Organization. Female life expectancy. WHO; 2021. [accessed 2021 Apr 9]. https://www.who.int/gho/women_and_health/mortality/life_expectancy_text/en/.
- Baumgartner A, Zueger N, Bargetzi A, Medinger M, Passweg JR, Stanga Z, Mueller B, Bargetzi M, Schuetz P. Association of nutritional parameters with clinical outcomes in patients with acute myeloid leukemia undergoing hematopoietic stem cell transplantation. Ann Nutr Metab. 2016;69(2):89–98. doi:https://doi.org/10.1159/000449451
- Gupta R, Jamal F, Yang D, Chendri C, Aldoss I, Malki MA, Mei M, Salhotra A, Dobrin S, Tran M, et al. Pulmonary hypertension is associated with increased nonrelapse mortality after allogeneic hematopoietic cell transplantation for myelofibrosis. Bone Marrow Transplant. 2020;55(5):877–883. doi:https://doi.org/10.1038/s41409-019-0741-8
- Takano K, Fuji S, Uchida N, Ogawa H, Ohashi K, Eto T, Sakamaki H, Morishima Y, Kato K, Suzuki R, et al. Pre-transplant diabetes mellitus is a risk factor for non-relapse mortality, especially infection-related mortality, after allogeneic hematopoietic SCT. Bone Marrow Transplant. 2015;50(4):553–558. doi:https://doi.org/10.1038/bmt.2014.315