153
Views
4
CrossRef citations to date
0
Altmetric
Article

Sesamol Augments Paclitaxel-Induced Apoptosis in Human Cervical Cancer Cell Lines

, , , , &
Pages 3692-3700 | Received 12 Aug 2021, Accepted 13 May 2022, Published online: 31 May 2022

References

  • Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN ­estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;70(4):313–4.
  • Jradi H, Bawazir A. Knowledge, attitudes, and practices among Saudi women regarding cervical cancer, human papillomavirus (HPV) and corresponding vaccine. Vaccine. 2019;37(3):530–7. doi:10.1016/j.vaccine.2018.11.065
  • Lapresa M, Parma G, Portuesi R, Colombo N. Neoadjuvant chemotherapy in cervical cancer: An update. Expert Rev Anticancer Ther. 2015;15(10):1171–81. doi:10.1586/14737140.2015.1079777
  • Loibl S, O’Shaughnessy J, Untch M, Sikov WM, Rugo HS, McKee MD, et al. Addition of the PARP inhibitor veliparib plus carboplatin or carboplatin alone to standard neoadjuvant chemotherapy in triple-negative breast cancer (BrighTNess): a randomized, phase 3 trial. Lancet Oncol. 2018;19(4):497–509.
  • Schmid P, Adams S, Rugo HS, Schneeweiss A, Barrios CH, Iwata H, Diéras V, Hegg R, Im S-A, Shaw Wright G, et al. Atezolizumab and nab-paclitaxel in advanced triple-negative breast cancer. N Engl J Med. 2018;379(22):2108–21. doi:10.1056/NEJMoa1809615
  • Dang YP, Yuan XY, Tian R, Li DG, Liu W. Curcumin improves the paclitaxel-induced apoptosis of HPV positive human cervical cancer cells via the NF κB p53 caspase 3 pathway. Exp Ther Med. 2015;9(4):1470–6. doi:10.3892/etm.2015.2240
  • Škubník J, Pavlíčková VS, Ruml T, Rimpelová S. Vincristine in combination therapy of cancer: Emerging trends in clinics. Biology. 2021;10(9):849. doi:10.3390/biology10090849
  • Khongkow P, Gomes AR, Gong C, Man EPS, Tsang JW-H, Zhao F, Monteiro LJ, Coombes RC, Medema RH, Khoo US, et al. Paclitaxel targets FOXM1 to regulate KIF20A in mitotic catastrophe and breast cancer paclitaxel resistance. Oncogene. 2016;35(8):990–1002. doi:10.1038/onc.2015.152
  • Muthusamy G, Gunaseelan S, Prasad NR. Ferulic acid reverses P-glycoprotein-mediated multidrug resistance via inhibition of PI3K/Akt/NF-κB signaling pathway. J Nutr Biochem. 2019;63:62–71. doi:10.1016/j.jnutbio.2018.09.022
  • Lovitt CJ, Shelper TB, Avery VM. Doxorubicin resistance in breast cancer cells is mediated by extracellular matrix proteins. BMC Cancer. 2018;18(1):41. doi:10.1186/s12885-017-3953-6
  • Lukhele ST, Motadi LR. Cannabidiol rather than Cannabis sativa extracts inhibit cell growth and induce apoptosis in cervical cancer cells. BMC Complement Altern Med. 2016;16(1):335. doi:10.1186/s12906-016-1280-0
  • Vidya Priyadarsini R, Senthil Murugan R, Maitreyi S, Ramalingam K, Karunagaran D, Nagini S. The flavonoid quercetin induces cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells through p53 induction and NF-κB inhibition. Eur J Pharmacol. 2010;649(1–3):84–91. doi:10.1016/j.ejphar.2010.09.020
  • Chen Y-J, Cheng Y-J, Hung AC, Wu Y-C, Hou M-F, Tyan Y-C, Yuan S-SF. The synthetic flavonoid WYC02-9 inhibits cervical cancer cell migration/invasion and angiogenesis via MAPK14 signaling. Gynecol Oncol. 2013;131(3):734–43. doi:10.1016/j.ygyno.2013.10.012
  • Kapinova A, Kubatka P, Golubnitschaja O, Kello M, Zubor P, Solar P, Pec M. Dietary phytochemicals in breast cancer research: Anticancer effects and potential utility for effective chemoprevention. Environ Health Prev Med. 2018;23(1):36.
  • Wu M-S, Aquino LBB, Barbaza MYU, Hsieh C-L, De Castro-Cruz KA, Yang L-L, Tsai P-W. Anti-inflammatory and anticancer properties of bioactive compounds from sesamum indicum L. A review. Molecules. 2019;24(24):4426. doi:10.3390/molecules24244426
  • Majdalawieh AF, Mansour ZR. Sesamol, a major lignan in sesame seeds (Sesamum indicum): Anti-cancer properties and mechanisms of action. Eur J Pharmacol. 2019;855:75–89. doi:10.1016/j.ejphar.2019.05.008
  • Bosebabu B, Cheruku SP, Chamallamudi MR, Nampoothiri M, Shenoy RR, Nandakumar K, Parihar VK, Kumar N. An appraisal of current pharmacological perspectives of sesamol: A review. Mini Rev Med Chem. 2020;20(11):988–1000. doi:10.2174/1389557520666200313120419
  • Liou CJ, Chen YL, Yu MC, Yeh KW, Shen SC, Huang WC. Sesamol alleviates airway hyperresponsiveness and oxidative stress in asthmatic mice. Antioxidants. 2020;9(4):295. doi:10.3390/antiox9040295
  • Ren B, Yuan T, Zhang X, Wang L, Pan J, Liu Y, Zhao B, Zhao W, Liu Z, Liu X, et al. Protective effects of sesamol on systemic inflammation and cognitive impairment in aging mice. J Agric Food Chem. 2020;68(10):3099–111. doi:10.1021/acs.jafc.9b07598
  • Murthy S, Hazli UHAM, Kong KW, Mai C-W, Leong C-O, Rahman NA, Lo KM, Chee CF. Identification of novel sesamol dimers with unusual methylenedioxy ring-opening skeleton and evaluation of their antioxidant and cytotoxic activities. Curr Org Synth. 2019;16(8):1166–73. doi:10.2174/1570179416666191003095253
  • Srisongkram T, Weerapreeyakul N, Kärkkäinen J, Rautio J. Role of L-type amino acid transporter 1 (LAT1) for the selective cytotoxicity of sesamol in human melanoma cells. Molecules. 2019;24(21):3869. doi:10.3390/molecules24213869
  • Abd Elrazik NA, El-Mesery M, El-Karef A, Eissa LA, El Gayar AM. Sesamol upreulates death receptors and acts as a chemosensitizer in solid ehrlich carcinoma model in mice. Nutr Cancer. 2021;74(1):250–64.
  • Kumar P, Nagarajan A, Uchil PD. Analysis of cell viability by the MTT assay. Cold Spring Harb Protoc. 2018;2018(6):pdb.prot095505. doi:10.1101/pdb.prot095505
  • Madeira K, Cerri M, Daltoé R, Herlinger A, Filho JA, Greco S, Rangel L. In vitro antineoplastic activity in triple-negative breast cancer cell line and in vivo. BMC Proc. 2014;8(S4):8–9. doi:10.1186/1753-6561-8-S4-P22
  • Singh S, Prasad NR, Chufan EE, Patel BA, Wang Y-J, Chen Z-S, Ambudkar SV, Talele TT. Design and synthesis of human ABCB1 (P-glycoprotein) inhibitors by peptide coupling of diverse chemical scaffolds on carboxyl and amino termini of (S)-valine-derived thiazole amino acid. J Med Chem. 2014;57(10):4058–72.
  • Prasad N, Shanmugham M. Radiosensitizing effect of sesamol on human cervical carcinoma cells. Int J Nutr Pharmacol Neurol Dis. 2012;2(3):210–6. doi:10.4103/2231-0738.99472
  • Khamphio M, Barusrux S, Weerapreeyakul N. Sesamol induces mitochondrial apoptosis pathway in HCT116 human colon cancer cells via pro-oxidant effect. Life Sci. 2016;158:46–56. doi:10.1016/j.lfs.2016.06.017
  • Nayak PG, Paul P, Bansal P, Kutty NG, Pai KSR. Sesamol prevents doxorubicin-induced oxidative damage and toxicity on H9c2 cardiomyoblasts. J Pharm Pharmacol. 2013;65(7):1083–93. doi:10.1111/jphp.12073
  • Muthusamy G, Balupillai A, Ramasamy K, Shanmugam M, Gunaseelan S, Mary B, Prasad NR. Ferulic acid reverses ABCB1-mediated paclitaxel resistance in MDR cell lines. Eur J Pharmacol. 2016;786:194–203. doi:10.1016/j.ejphar.2016.05.023
  • Shukla AS, Jha AK, Kumari R, Rawat K, Syeda S, Shrivastava A. Role of catechins in chemosensitization. In: Role of nutraceuticals in chemoresistance to cancer; London: Academic Press; 2018. p. 169–98.
  • Sordillo PP, Helson L. Curcumin and cancer stem cells: Curcumin has asymmetrical effects on cancer and normal stem cells. Anticancer Res. 2015;35(2):599–614.
  • Rajendra Prasad N, Karthikeyan A, Karthikeyan S, Venkata Reddy B. Inhibitory effect of caffeic acid on cancer cell proliferation by oxidative mechanism in human HT-1080 fibrosarcoma cell line. Mol Cell Biochem. 2011;349(1–2):11–9. doi:10.1007/s11010-010-0655-7
  • Galati G, Sabzevari O, Wilson JX, O’Brien PJ. Prooxidant activity and cellular effects of the phenoxyl radicals of dietary flavonoids and other polyphenolics. Toxicology. 2002;177(1):91–104. doi:10.1016/S0300-483X(02)00198-1
  • Miliukiene V, Nemeikaite-Čeniene A, Čenas N. Prooxidant cytotoxicity of polyphenolic compounds in primary mice splenocytes: The role of redox potential and lipophilicity. Chemija. 2014;25(4):218–23.
  • Chikara S, Nagaprashantha LD, Singhal J, Horne D, Awasthi S, Singhal SS. Oxidative stress and dietary phytochemicals: Role in cancer chemoprevention and treatment. Cancer Lett. 2018;413:122–34. doi:10.1016/j.canlet.2017.11.002
  • Prasad N, Muthusamy G, Shanmugam M, Ambudkar S. South Asian medicinal compounds as modulators of resistance to chemotherapy and radiotherapy. Cancers (Basel). 2016;8(3):32. doi:10.3390/cancers8030032
  • Farhan M, Khan HY, Oves M, Al-Harrasi A, Rehmani N, Arif H, Hadi SM, Ahmad A. Cancer therapy by catechins involves redox cycling of copper ions and generation of reactive Oxygen species. Toxins (Basel). 2016;8(2):37. doi:10.3390/toxins8020037
  • Sarkar N, Das B, Bishayee A, Sinha D. Arsenal of phytochemicals to combat against arsenic-induced mitochondrial stress and cancer. Antioxid Redox Signal. 2020;33(17):1230–56. doi:10.1089/ars.2019.7950
  • Liu Z, Ren B, Wang Y, Zou C, Qiao Q, Diao Z, Mi Y, Zhu D, Liu X. Sesamol induces human hepatocellular carcinoma cells apoptosis by impairing mitochondrial function and suppressing autophagy. Sci Rep. 2017;7:45728. doi:10.1038/srep45728
  • Sundaram MK, Khan MA, Alalami U, Somvanshi P, Bhardwaj T, Pramodh S, Raina R, Shekfeh Z, Haque S, Hussain A. Phytochemicals induce apoptosis by modulation of nitric oxide signaling pathway in cervical cancer cells. Eur Rev Med Pharmacol Sci. 2020;24(22):11827–44.
  • Bhardwaj R, Sanyal SN, Vaiphei K, Kakkar V, Deol PK, Kaur IP, Kaur T. Sesamol induces apoptosis by altering expression of Bcl-2 and Bax proteins and modifies skin tumor development in Balb/c mice. Anticancer Agents Med Chem. 2017;17(5):726–33. doi:10.2174/1871520616666160819103249
  • Wang TH, Wang HS, Soong YK. Paclitaxel-induced cell death: Where the cell cycle and apoptosis come together. Cancer. 2000;88(11):2619–28. doi:10.1002/1097-0142(20000601)88:11<2619::AID-CNCR26>3.0.CO;2-J
  • Bashari MH, Damara FA, Hardani IN, Pradini GW, Putri T, Ariyanto EF. Generating paclitaxel-resistant in cervical cancer HeLa cell line. Indones J Cancer Chemoprevent. 2020;11(2):90. doi:10.14499/indonesianjcanchemoprev11iss2pp90-96
  • Aborehab NM, Osama N. Effect of Gallic acid in potentiating chemotherapeutic effect of Paclitaxel in HeLa cervical cancer cells. Cancer Cell Int. 2019;19(1):154. doi:10.1186/s12935-019-0868-0

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.