Genome-Wide Association Study of Metachronous Colorectal Adenoma Risk among Participants in the Selenium Trial

References

• Siegel RL, Miller KD, Jemal A. Cancer statistics, 2019. CA A Cancer J Clin. 2019;69(1):7–34. doi:10.3322/caac.21551
   PubMed Web of Science ®Google Scholar
• Siegel RL, Miller KD, Fuchs HE, Jemal A. Cancer statistics, 2022. CA A Cancer J Clin. 2022;72(1):7–33. doi:10.3322/caac.21708
   PubMed Web of Science ®Google Scholar
• Bond JH. Polyp guideline: diagnosis, treatment, and surveillance for patients with colorectal polyps. Am J Gastroenterol. 2000;95(11):3053–63. doi:10.1111/j.1572-0241.2000.03434.x
   PubMed Web of Science ®Google Scholar
• Stewart SL, Wike JM, Kato I, Lewis DR, Michaud F. A population-based study of colorectal cancer histology in the United States, 1998–2001. Cancer. 2006;107(5 Suppl):1128–41. doi:10.1002/cncr.22010
   PubMed Web of Science ®Google Scholar
• Brenner H, Hoffmeister M, Stegmaier C, Brenner G, Altenhofen L, Haug U. Risk of progression of advanced adenomas to colorectal cancer by age and sex: estimates based on 840 149 screening colonoscopies. Gut. 2007;56(11):1585–9. doi:10.1136/gut.2007.122739
   PubMed Web of Science ®Google Scholar
• Hermsen M, Postma C, Baak J, Weiss M, Rapallo A, Sciutto A, Roemen G, Arends J-W, Williams R, Giaretti W, et al. Colorectal adenoma to carcinoma progression follows multiple pathways of chromosomal instability. Gastroenterology. 2002;123(4):1109–19. doi:10.1053/gast.2002.36051
   PubMed Web of Science ®Google Scholar
• Corley DA, Jensen CD, Marks AR, Zhao WK, de Boer J, Levin TR, Doubeni C, Fireman BH, Quesenberry CP. Variation of adenoma prevalence by age, sex, race, and colon location in a large population: implications for screening and quality programs. Clin Gastroenterol Hepatol. 2013;11(2):172–80. doi:10.1016/j.cgh.2012.09.010
   PubMed Web of Science ®Google Scholar
• Levin B, Lieberman DA, McFarland B, Andrews KS, Brooks D, Bond J, Dash C, Giardiello FM, Glick S, Johnson D, American College of Radiology Colon Cancer Committee, et al. Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, 2008: A Joint Guideline From the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. Gastroenterology. 2008;134(5):1570–95. doi:10.1053/j.gastro.2008.02.002
   PubMed Web of Science ®Google Scholar
• Johnson CM, Wei C, Ensor JE, Smolenski DJ, Amos CI, Levin B, Berry DA. Meta-analyses of colorectal cancer risk factors. Cancer Causes Control. 2013;24(6):1207–22. doi:10.1007/s10552-013-0201-5
   PubMed Web of Science ®Google Scholar
• US Preventive Services Task Force Screening for colorectal cancer: US Preventive Services Task Force recommendation statement. JAMA. 2016;315(23):2564–75.
   PubMed Web of Science ®Google Scholar
• Jacobs ET, Gupta S, Baron JA, Cross AJ, Lieberman DA, Murphy G, Martínez ME. Family history of colorectal cancer in first-degree relatives and metachronous colorectal adenoma. Am J Gastroenterol. 2018;113(6):899–905. doi:10.1038/s41395-018-0007-x
   PubMed Web of Science ®Google Scholar
• Bermano G, Pagmantidis V, Holloway N, Kadri S, Mowat NAG, Shiel RS, Arthur JR, Mathers JC, Daly AK, Broom J, et al. Evidence that a polymorphism within the 3’UTR of glutathione peroxidase 4 is functional and is associated with susceptibility to colorectal cancer. Genes Nutr. 2007;2(2):225–32. doi:10.1007/s12263-007-0052-3
   PubMed Web of Science ®Google Scholar
• Fedirko V, Jenab M, Méplan C, Jones JS, Zhu W, Schomburg L, Siddiq A, Hybsier S, Overvad K, Tjønneland A, et al. Association of selenoprotein and selenium pathway genotypes with risk of colorectal cancer and interaction with selenium status. Nutrients. 2019;11(4):935. doi:10.3390/nu11040935
   PubMed Web of Science ®Google Scholar
• Hansen R, Saebø M, Skjelbred CF, Nexø BA, Hagen PC, Bock G, Bowitz Lothe IM, Johnson E, Aase S, Hansteen I-L, et al. GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colorectal adenomas and colorectal cancer. Cancer Lett. 2005;229(1):85–91. doi:10.1016/j.canlet.2005.04.019
   PubMed Web of Science ®Google Scholar
• Haug U, Poole EM, Xiao L, Curtin K, Duggan D, Hsu L, Makar KW, Peters U, Kulmacz RJ, Potter JD, et al. Glutathione peroxidase tagSNPs: associations with rectal cancer but not with colon cancer. Genes Chromosomes Cancer. 2012;51(6):598–605. doi:10.1002/gcc.21946
   PubMed Web of Science ®Google Scholar
• Méplan C, Hughes DJ, Pardini B, Naccarati A, Soucek P, Vodickova L, Hlavatá I, Vrána D, Vodicka P, Hesketh JE, et al. Genetic variants in selenoprotein genes increase risk of colorectal cancer. Carcinogenesis. 2010;31(6):1074–9. doi:10.1093/carcin/bgq076
   PubMed Web of Science ®Google Scholar
• Peters U, Chatterjee N, Hayes RB, Schoen RE, Wang Y, Chanock SJ, Foster CB. Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma. Cancer Epidemiol Biomarkers Prev. 2008;17(5):1144–54. doi:10.1158/1055-9965.EPI-07-2947
   PubMed Web of Science ®Google Scholar
• Slattery ML, Lundgreen A, Welbourn B, Corcoran C, Wolff RK. Genetic variation in selenoprotein genes, lifestyle, and risk of colon and rectal cancer. PLoS One. 2012;7(5):e37312. doi:10.1371/journal.pone.0037312
   PubMed Web of Science ®Google Scholar
• Sutherland A, Kim DH, Relton C, Ahn YO, Hesketh J. Polymorphisms in the selenoprotein S and 15-kDa selenoprotein genes are associated with altered susceptibility to colorectal cancer. Genes Nutr. 2010;5(3):215–23. doi:10.1007/s12263-010-0176-8
   PubMed Web of Science ®Google Scholar
• Takata Y, Kristal AR, King IB, Song X, Diamond AM, Foster CB, Hutter CM, Hsu L, Duggan DJ, Langer RD, et al. Serum selenium, genetic variation in selenoenzymes, and risk of colorectal cancer: primary analysis from the Women’s Health Initiative Observational Study and meta-analysis. Cancer Epidemiol Biomarkers Prev. 2011;20(9):1822–30. doi:10.1158/1055-9965.EPI-11-0364
   PubMed Web of Science ®Google Scholar
• Xie W, Yang M, Chan J, Sun T, Mucci LA, Penney KL, Lee G-SM, Kantoff PW. Association of genetic variations of selenoprotein genes, plasma selenium levels, and prostate cancer aggressiveness at diagnosis. Prostate. 2016;76(7):691–9. doi:10.1002/pros.23160
   PubMed Web of Science ®Google Scholar
• Hofer P, Hagmann M, Brezina S, Dolejsi E, Mach K, Leeb G, Baierl A, Buch S, Sutterlüty-Fall H, Karner-Hanusch J, et al. Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas. Oncotarget. 2017;8(58):98623–34. doi:10.18632/oncotarget.21697
   PubMedGoogle Scholar
• Wang J, Carvajal-Carmona LG, Chu J-H, Zauber AG, Kubo M, Matsuda K, Dunlop M, Houlston RS, Sieber O, Lipton L, APC Trial Collaborators, et al. Germline variants and advanced colorectal adenomas: adenoma prevention with Celecoxib Trial Genome-wide Association Study. Clin Cancer Res. 2013;19(23):6430–7. doi:10.1158/1078-0432.CCR-13-0550
   PubMed Web of Science ®Google Scholar
• Duffield-Lillico AJ, Dalkin BL, Reid ME, Turnbull BW, Slate EH, Jacobs ET, Marshall JR, Clark LC, for the Nutritional Prevention of Cancer Study Group Selenium supplementation, baseline plasma selenium status and incidence of prostate cancer: an analysis of the complete treatment period of the Nutritional Prevention of Cancer Trial. BJU Int. 2003;91(7):608–12. doi:10.1046/j.1464-410X.2003.04167.x
   PubMed Web of Science ®Google Scholar
• Reid ME, Duffield-Lillico AJ, Sunga A, Fakih M, Alberts DS, Marshall JR. Selenium supplementation and colorectal adenomas: an analysis of the nutritional prevention of cancer trial. Int J Cancer. 2006;118(7):1777–81. doi:10.1002/ijc.21529
   PubMed Web of Science ®Google Scholar
• Thompson P, Roe DJ, Fales L, Buckmeier J, Wang F, Hamilton SR, Bhattacharyya A, Green S, Hsu C-H, Chow H-HS, et al. Design and baseline characteristics of participants in a phase III randomized trial of celecoxib and selenium for colorectal adenoma prevention. Cancer Prev Res (Phila). 2012;5(12):1381–93. doi:10.1158/1940-6207.CAPR-12-0204
   PubMed Web of Science ®Google Scholar
• Saini SD, Kim HM, Schoenfeld P. Incidence of advanced adenomas at surveillance colonoscopy in patients with a personal history of colon adenomas: a meta-analysis and systematic review. Gastrointest Endosc. 2006;64(4):614–26. doi:10.1016/j.gie.2006.06.057
   PubMed Web of Science ®Google Scholar
• Half E, Bercovich D, Rozen P. Familial adenomatous polyposis. Orphanet J Rare Dis. 2009;4(1):22. doi:10.1186/1750-1172-4-22
   PubMed Web of Science ®Google Scholar
• Lynch HT, Snyder CL, Shaw TG, Heinen CD, Hitchins MP. Milestones of Lynch syndrome: 1895–2015. Nat Rev Cancer. 2015;15(3):181–94. doi:10.1038/nrc3878
   PubMed Web of Science ®Google Scholar
• McCarthy S, Das S, Kretzschmar W, Delaneau O, Wood AR, Teumer A, Kang HM, Fuchsberger C, Danecek P, Sharp K, Haplotype Reference Consortium, et al. A reference panel of 64,976 haplotypes for genotype imputation. Nat Genet. 2016;48(10):1279–83.
   PubMed Web of Science ®Google Scholar
• Das S, Forer L, Schönherr S, Sidore C, Locke AE, Kwong A, Vrieze SI, Chew EY, Levy S, McGue M, et al. Next-generation genotype imputation service and methods. Nat Genet. 2016;48(10):1284–7. doi:10.1038/ng.3656
   PubMed Web of Science ®Google Scholar
• Loh P-R, Danecek P, Palamara PF, Fuchsberger C, A Reshef Y, K Finucane H, Schoenherr S, Forer L, McCarthy S, Abecasis GR, et al. Reference-based phasing using the Haplotype Reference Consortium panel. Nat Genet. 2016;48(11):1443–8. doi:10.1038/ng.3679
   PubMed Web of Science ®Google Scholar
• Gsur A, Baierl A, Brezina S. Colorectal Cancer Study of Austria (CORSA): A population-based multicenter study. Biology (Basel). 2021;10(8):722. doi:10.3390/biology10080722
   PubMedGoogle Scholar
• Chang CC, Chow CC, Tellier LC, Vattikuti S, Purcell SM, Lee JJ. Second-generation PLINK: rising to the challenge of larger and richer datasets. GigaSci. 2015;4(1):1–16. doi:10.1186/s13742-015-0047-8
   PubMedGoogle Scholar
• Ungerbäck J, Belenki D, Jawad ul-Hassan A, Fredrikson M, Fransén K, Elander N, Verma D, Söderkvist P. Genetic variation and alterations of genes involved in NFκB/TNFAIP3- and NLRP3-inflammasome signaling affect susceptibility and outcome of colorectal cancer. Carcinogenesis. 2012;33(11):2126–34. doi:10.1093/carcin/bgs256
   PubMed Web of Science ®Google Scholar
• He J, Wilkens LR, Stram DO, Kolonel LN, Henderson BE, Wu AH, Le Marchand L, Haiman CA. Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations. Cancer Epidemiol Biomarkers Prev. 2011;20(1):70–81. doi:10.1158/1055-9965.EPI-10-0892
   PubMed Web of Science ®Google Scholar
• Tanikawa C, Kamatani Y, Takahashi A, Momozawa Y, Leveque K, Nagayama S, Mimori K, Mori M, Ishii H, Inazawa J, et al. GWAS identifies two novel colorectal cancer loci at 16q24.1 and 20q13.12. Carcinogenesis. 2018;39(5):652–60. doi:10.1093/carcin/bgy026
   PubMed Web of Science ®Google Scholar
• Segditsas S, Tomlinson I. Colorectal cancer and genetic alterations in the Wnt pathway. Oncogene. 2006;25(57):7531–7. doi:10.1038/sj.onc.1210059
   PubMed Web of Science ®Google Scholar
• Schatoff EM, Leach BI, Dow LE. Wnt signaling and colorectal cancer. Curr Colorectal Cancer Rep. 2017;13(2):101–10. doi:10.1007/s11888-017-0354-9
   PubMed Web of Science ®Google Scholar
• Morris LGT, Ramaswami D, Chan TA. The FAT epidemic: A gene family frequently mutated across multiple human cancer types. Cell Cycle. 2013;12(7):1011–2. doi:10.4161/cc.24305
   PubMed Web of Science ®Google Scholar
• Katoh Y, Katoh M. Comparative integromics on FAT1, FAT2, FAT3 and FAT4. Int J Mol Med. 2006;18(3):523–8. doi:10.3892/ijmm.18.3.523
   PubMed Web of Science ®Google Scholar
• Zhang X, Liu J, Liang X, Chen J, Hong J, Li L, He Q, Cai X. History and progression of Fat cadherins in health and disease. Onco Targets Ther. 2016;9:7337–43. doi:10.2147/OTT.S111176
   PubMed Web of Science ®Google Scholar
• Morris LGT, Kaufman AM, Gong Y, Ramaswami D, Walsh LA, Turcan Ş, Eng S, Kannan K, Zou Y, Peng L, et al. Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation. Nat Genet. 2013;45(3):253–61. doi:10.1038/ng.2538
   PubMed Web of Science ®Google Scholar
• Rohrbeck A, Borlak J. Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to advanced lung adenocarcinomas induced by c-Raf-1. PLoS One. 2009;4(10):e7315. doi:10.1371/journal.pone.0007315
   PubMed Web of Science ®Google Scholar
• Thi HTH, Hong S. Inflammasome as a therapeutic target for cancer prevention and treatment. J Cancer Prev. 2017;22(2):62–73. doi:10.15430/JCP.2017.22.2.62
   PubMed Web of Science ®Google Scholar
• Moossavi M, Parsamanesh N, Bahrami A, Atkin SL, Sahebkar A. Role of the NLRP3 inflammasome in cancer. Mol Cancer. 2018;17(1):158. doi:10.1186/s12943-018-0900-3
   PubMed Web of Science ®Google Scholar
• Dupaul-Chicoine J, Yeretssian G, Doiron K, Bergstrom KSB, McIntire CR, LeBlanc PM, Meunier C, Turbide C, Gros P, Beauchemin N, et al. Control of intestinal homeostasis, colitis, and colitis-associated colorectal cancer by the inflammatory caspases. Immunity. 2010;32(3):367–78. doi:10.1016/j.immuni.2010.02.012
   PubMed Web of Science ®Google Scholar
• Dupaul-Chicoine J, Arabzadeh A, Dagenais M, Douglas T, Champagne C, Morizot A, Rodrigue-Gervais IG, Breton V, Colpitts SL, Beauchemin N, et al. The Nlrp3 inflammasome suppresses colorectal cancer metastatic growth in the liver by promoting natural killer cell tumoricidal activity. Immunity. 2015;43(4):751–63. doi:10.1016/j.immuni.2015.08.013
   PubMed Web of Science ®Google Scholar
• Thompson PA, Ashbeck EL, Roe DJ, et al. Selenium supplementation for prevention of colorectal adenomas and risk of associated type 2 diabetes. J Natl Cancer Inst. 2016;108(12):604–10.
   Google Scholar
• Huang H, Li X, Wang Z, Lin X, Tian Y, Zhao Q, Zheng P. Anti-inflammatory effect of selenium on lead-induced testicular inflammation by inhibiting NLRP3 inflammasome activation in chickens. Theriogenology. 2020;155:139–49. doi:10.1016/j.theriogenology.2020.06.015
   PubMed Web of Science ®Google Scholar
• Qing Z, Kaixin Z, Yanfei H, Yiming Z, Hua X, Ling Z, Guangliang S, Shu L. MicroRNA-223 triggers inflammation in porcine aorta by activating NLRP3 inflammasome under selenium deficiency. J Cell Physiol. 2021;236(6):4555–64. doi:10.1002/jcp.30178
   PubMed Web of Science ®Google Scholar
• Bi C-L, Zhang S-J, Shen Y-Z, Pauline M, Li H, Tang H. Selenium plays an anti-inflammatory role by regulation NLRP3 inflammasome in Staphylococcus aureus-Infected mouse mammary gland. Biol Trace Elem Res. 2021;199(2):604–7. doi:10.1007/s12011-020-02166-z
   PubMed Web of Science ®Google Scholar
• Qu J, Wang W, Zhang Q, Li S. Inhibition of lipopolysaccharide-induced inflammation of chicken liver tissue by selenomethionine via TLR4-NF-κB-NLRP3 signaling pathway. Biol Trace Elem Res. 2020;195(1):205–10. doi:10.1007/s12011-019-01841-0
   PubMed Web of Science ®Google Scholar