75
Views
0
CrossRef citations to date
0
Altmetric
Article

Findings from Positron Emission Tomography-Computed Tomography with 18F-Fluorodeoxyglucose Uncover a Potential Marker of Nutritional Status in Cancer Patients: A Cross-Sectional Pilot Study

, , , , & ORCID Icon
Pages 1109-1115 | Received 01 Jun 2022, Accepted 14 Dec 2022, Published online: 09 Mar 2023

References

  • Elit LM, Fyles AW, Gu C-S, Pond GR, D’Souza D, SAMant R, Anthes M, Thomas G, Filion M, Arsenault J, et al. Effect of positron emission tomography Imaging in women with locally advanced cervical cancer - A randomized clinical trial. JAMA Netw Open. 2018;1(5):e182081. doi:10.1001/jamanetworkopen.2018.2081
  • Vella M, Meyer CS, Zhang N, Cohen BE, Whooley MA, Wang S, Hope MD. Association of receipt of positron emission tomography–computed tomography with non–small cell lung cancer mortality in the veterans affairs health care system. JAMA Netw Open. 2019;2(11):e1915828. doi:10.1001/jamanetworkopen.2019.15828
  • Walter MA. The role of positron emission tomography-computed tomography in the workup of non-small cell lung cancer. JAMA Netw Open. 2019;2(11):e1915873. doi:10.1001/jamanetworkopen.2019.15873
  • Abbasi J. PET-CT improved high-risk prostate cancer staging in trial. JAMA. 2020;323(18):1764. doi:10.1001/jama.2020.6994
  • Jamsek J, Hocevar M, Bergant D, Zaletel K, Rep S, Lezaic L. Diagnostic values of [18FDG] Fluorocholine PET/CT in detection of primary medullary thyroid cancer. Ann Nucl Med. 2021;35(4):429–37. 10.1007/s12149-021-01579-7.
  • Coenen HH, Elsinga PH, Iwata R, Kilbourn MR, Pillai MRA, Rajan MGR, Wagner HN, Zaknun JJ. Fluorine-18 radiopharmaceuticals beyond [18F]FDG for use in oncology and neurosciences. Nucl Med Biol. 2010;37(7):727–40. doi: 10.1016/j.nucmedbio.2010.04.185
  • Fox JJ, Gavane SC, Blanc-Autran E, Nehmeh S, Gönen M, BeaTie B, Vargas HA, Schöder H, Humm JL, Fine SW, et al. Positron emission tomography/computed tomography–based assessments of androgen receptor expression and glycolytic activity as a prognostic biomarker for metastatic castration-resistant prostate ­cancer. JAMA Oncol. 2018;4(2):217–24. doi:10.1001/jamaoncol.2017.3588
  • Khandani AH, Wahl RL. Applications of PET in liver imaging. Radiol Clin North Am. 2005;43(5):849–60. 10.1016/j.rcl.2005.05.008
  • Fearon KC, Voss AC, Hustead DS, Cancer Cachexia Study Group. Definition of cancer cachexia: Effect of weight loss, reduced food intake, and systemic inflammation on functional status and prognosis. Am J Clin Nutr. 2006;83(6):1345–50. doi: 10.1093/ajcn/83.6.1345
  • Caan BJ, Cespedes Feliciano EM, Prado CM, Alexeeff S, Kroenke CH, Bradshaw P, Quesenberry CP, Weltzien EK, Castillo AL, OLObatuyi TA, et al. Association of muscle and adiposity measured by computed tomography with survival in patients with nonmetastatic breast cancer. JAMA Oncol. 2018;4(6):798–804. doi:10.1001/jamaoncol.2018.0137
  • Cespedes Feliciano EM, Chen WY, Lee V, Albers KB, Prado CM, Alexeeff S, Xiao J, Shachar SS, Caan BJ. Body composition, adherence to anthracycline and taxane-based chemotherapy, and survival after nonmetastatic breast cancer. JAMA Oncol. 2020;6(2):264–70. doi:10.1001/jamaoncol.2019.4668
  • Marshall KM, Loeliger J, Nolte L, Kelaart A, Kiss NK. Prevalence of malnutrition and impact on clinical outcomes in cancer services: A comparison of two time points. Clin Nutr. 2019;38(2):644–51. doi: 10.1016/j.clnu.2018.04.007
  • Evans WJ. Nutritional support should target the cause of malnutrition in hospitalized patients. JAMA Netw Open. 2021;4(1):e2033925. doi:10.1001/jamanetworkopen.2020.33925
  • Martin L, Birdsell L, Macdonald N, Reiman T, Clandinin MT, McCargar LJ, Murphy R, Ghosh S, Sawyer MB, Baracos VE. Cancer cachexia in the age of obesity: Skeletal muscle depletion is a powerful prognostic factor, independent of body mass index. J Clin Oncol. 2013;31(12):1539–47. 10.1200/JCO.2012.45.2722
  • Miola TM, Santos da Conceição EL, de Oliveira Souza J, Barbosa PNV, Coimbra FJF, Bitencourt AGV. CT assessment of nutritional status and lean body mass in gastric and esophageal cancer. Appl Cancer Res. 2018;38(1):12. doi: 10.1186/s41241-018-0063-y 10.1186/s41241-018-0063-y
  • Prado CMM, Mourtzakis M, Baracos V, Reiman T, Sawyer MB. Overweight and obese patients with solid tumors may have sarcopenia, poor prognosis and early features of cachexia. Int J Body Compos Res. 2010;8(1):7–15.
  • Otomi Y, Otsuka H, Terazawa K, Kondo M, Arai Y, Yamanaka M, Otomo M, Abe T, Shinya T, Harada M. A reduced liver 18 F-FDG uptake may be related to hypoalbuminemia in patients with malnutrition. Ann Nucl Med. 2019;33(9):689–96. doi: 10.1007/s12149-019-01377-2
  • De Graaf W, Bennink RJ, Veteläinen R, van Gulik TM. Nuclear imaging techniques for the assessment of hepatic function in liver surgery and transplantation. J Nucl Med. 2010;51(5):742–52. doi: 10.2967/jnumed.109.069435
  • Keramida G, Hunter J, Dizdarevic S, Peters AM. Heterogeneity of intrahepatic fat distribution determined by (18)F-FDG PET and CT. Ann Nucl Med. 2016;30(3):200–6. doi: 10.1007/s12149-015-1045-8
  • Dolan DR, Maclay JD, Abbass T, Buali F, MacLeod N. The relationship between 18FDG-PETCT derived tumour metabolic activity, nutritional risk, body composition, systemic inflammation and survival in ­patients with lung cancer. Nature. 2020;10:10819.
  • Yue X, Wang J, Ye F, Xiao D. Mean standardized uptake value (SUVmean) and global hepatic glycolysis as potential imaging markers reflecting hepatic functional capacity: Evidence from 18F-FDG PET/CT. Hippokratia. 2018;22(4):122–6.
  • Baker JP, Detsky AS, Wesson DE, Wolman SL, Stewart S, Whitewell J, Langer B, Jeejeebhoy KN. Nutritional assessment: A comparison of clinical judgement and objective measurements. N Engl J Med. 1982;306(16):969–72. doi: 10.1056/NEJM198204223061606. PMID: 6801515
  • Correia MITD. Empowerment on the fight against malnutrition. J Parenter Enteral Nutr. 2018;42(4):672–674. doi: 10.1002/jpen.1161
  • Butterworth CE. The skeleton in the hospital closet. 1974. Nutrition. 1994;10(5):435–41. discussion 435, 441. PMID: 7819664.
  • Kathiresan AS, Brookfield KF, Schuman SI, Lucci JA. Malnutrition as a predictor of poor postoperative outcomes in gynecologic cancer patients. Arch Gynecol Obstet. 2011;284(2):445–51. 10.1007/s00404-010-1659-y
  • Capuano G, Gentile PC, Bianciardi F, Tosti M, Palladino A, Di Palma M. Prevalence and influence of malnutrition on quality of life and performance status in patients with locally advanced head and neck cancer before treatment. Support Care Cancer. 2010;18(4):433–7. 10.1007/s00520-009-0681-8
  • Nicholson JP, Wolmarans MR, Park GR. The role of albumin in critical illness. Br J Anaesth. 2000;85(4):599–610. 10.1093/bja/85.4.599
  • Berardi G, Colasanti M, Ettorre GM. Association of sarcopenia and body composition with postoperative 90-day morbidity after liver resection for malignant tumors - Reply. JAMA Surg. 2021;156(6):590–1. doi:10.1001/jamasurg.2021.0234
  • Brown JC, Caan BJ, Prado CM, Weltzien E, Xiao J, Cespedes FelICiano EM, Kroenke CH, Meyerhardt JA. Body composition and cardiovascular events in patients with colorectal cancer: A population-based retrospective cohort study. JAMA Oncol. 2019;5(7):967–72. doi:10.1001/jamaoncol.2019.0695
  • Yilmaz M, Atilla FD, Sahin F, Saydam G. The effect of malnutrition on mortality in hospitalized patients with hematologic malignancy. Support Care Cancer. 2020;28(3):1441–8. doi: 10.1007/s00520-019-04952-5
  • Bullock AF, Greenley SL, McKenzie GAG, Paton LW, Johnson Mri J. Relationship between markers of malnutrition and clinical outcomes in older adults with cancer: Systematic review, narrative synthesis and meta-analysis. Eur J Clin Nutr. 2020;74(11):1519–35. doi: 10.1038/s41430-020-0629-0
  • Sandini M, Patino M, Ferrone CR, Alvarez-Pérez CA, Honselmann KC, Paiella S, Catania M, Riva L, Tedesco G, Casolino R, et al. Association between changes in body composition and neoadjuvant treatment for pancreatic cancer. JAMA Surg. 2018;153(9):809–15. doi:10.1001/jamasurg.2018.0979
  • Bandera EV, John EM. Obesity, body composition, and breast cancer: An evolving science. JAMA Oncol. 2018;4(6):804–5. doi:10.1001/jamaoncol.2018.0125
  • Almasaudi AS, McSorley ST, Dolan RD, Edwards CA, McMillan DC. The relation between Malnutrition Universal Screening Tool (MUST), computed tomography–derived body composition, systemic inflammation, and clinical outcomes in patients undergoing surgery for colorectal cancer. Am J Clin Nutr. 2019;110(6):1327–34. doi:10.1093/ajcn/nqz230
  • Wells JCK. Using body composition assessment to evaluate the double burden of malnutrition. Ann Nutr Metab. 2019;75(2):103–8. doi: 10.1159/000503666
  • Huang DD, Yu DY, Song HN. The relationship between the GLIM-defined malnutrition, body composition and functional parameters, and clinical outcomes in elderly patients undergoing radical gastrectomy for gastric cancer. Eur J Surg Oncol. 2021;47(9):2323–2331. doi: 10.1016/j.ejso.2021.02.032.
  • Longo DL. Tumor heterogeneity and personalized medicine. N Engl J Med. 2012;366(10):956–7. doi: 10.1056/NEJMe1200656
  • van Zutphen T, Ciapaite J, Bloks VW, Ackereley C, Gerding A, Jurdzinski A, de Moraes RA, Zhang L, Wolters JC, Bischoff Rne, et al. Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction. J Hepatol. 2016;65(6):1198–208. doi: 10.1016/j.jhep.2016.05.046
  • Danielski M, Ikizler TA, McMonagle E, Kane JC, Pupim L, Morrow J, Himmelfarb J. Linkage of hypoalbuminemia, inflammation, and oxidative stress in patients receiving maintenance hemodialysis therapy. Am J Kidney Dis. 2003;42(2):286–94. doi: 10.1016/s0272-6386(03)00653-x
  • Cooper BA, Penne EL, Bartlett LH, Pollock CA. Protein malnutrition and hypoalbuminemia as predictors of vascular events and mortality in ESRD. Am J Kidney Dis. 2004;43(1):61–6. doi: 10.1053/j.ajkd.2003.08.045
  • Nazha B, Moussaly E, Zaarour M, Weerasinghe C, Azab B. Hypoalbuminemia in colorectal cancer prognosis: Nutritional marker or inflammatory surrogate? World J Gastrointest Surg. 2015;7(12):370–7. 10.4240/wjgs.v7.i12.370

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.