Syringic acid Attenuates Oxidative Stress in Plasma and Peripheral Blood Mononuclear Cells of Patients with Acute Myeloid Leukemia

References

• Ghazawi F, Le M, Rahme E, Roshdy O, Popradi G, Glassman S, et al. Analysis of acute myeloid leukemia (AML) incidence and geographic distribution in Canada from 1992 to 2010. J Am Acad Dermatol. 2018;125(11):1886–1897.
   Google Scholar
• Reta C, Altamirano L, Gonzalez JA, Diaz-Hernandez R, Peregrina H, Olmos I, Alonso JE, Lobato R. Segmentation and classification of bone marrow cells images using contextual information for medical diagnosis of acute leukemias. PLoS One. 2015;10(6):e0130805. 10.1371/journal.pone.0130805
   PubMed Web of Science ®Google Scholar
• Zhou J, Chng W-J. Identification and targeting leukemia stem cells: The path to the cure for acute myeloid leukemia. World J Stem Cells. 2014;6(4):473–84. 10.4252/wjsc.v6.i4.473
   PubMedGoogle Scholar
• Bispo JAB, Pinheiro PS, Kobetz EK. Epidemiology and etiology of leukemia and lymphoma. Cold Spring Harb Perspect Med. 2020;10(6):a034819. 10.1101/cshperspect.a034819
   PubMed Web of Science ®Google Scholar
• Hasanpour-Heidari S, Jafari-Delouei N, Shokoohifar N, Sedaghat SM, Moghaddami A, Hosseinpour R, Poorabbasi M, Gholami M, Semnani S, Naeimi-Tabiei M, et al. Completeness and accuracy of death registry data in Golestan, Iran. Arch Iran Med. 2019;22(1):1–6.
   PubMed Web of Science ®Google Scholar
• Ranjbar M, Barouni M, Moazed V, Fallahzadeh H, Sheikholeslami S. Survival rate of patients with acute leukemia: a case study in Iran. Evidence Based Health Policy Manage Econ. 2020;4(4):234–41.
   Google Scholar
• Fathi A, Bahadoram M, Amani F. Epidemiology of childhood cancer in northwest Iran. Asian Pac J Cancer Prev. 2015;16(13):5459–62. 10.7314/apjcp.2015.16.13.5459
   PubMedGoogle Scholar
• Azim M, Mohammad Saeid R, Amir Abbas Hedayati A, Maryam T, Mohammad F, Mardawig A, et al. Features of childhood acute myeloid leukemia in Iran: a report from double center study. Acta Med Iran. 2015;53(12):749–52.
   PubMedGoogle Scholar
• Prieto-Bermejo R, Romo-González M, Pérez-Fernández A, Ijurko C, Hernández-Hernández Á. Reactive oxygen species in haematopoiesis: leukaemic cells take a walk on the wild side. J Exp Clin Cancer Res. 2018;37(1):125. 10.1186/s13046-018-0797-0
   PubMedGoogle Scholar
• Trombetti S, Cesaro E, Catapano R, Sessa R, Lo Bianco A, Izzo P, Grosso M. Oxidative stress and ROS-mediated signaling in leukemia: novel promising perspectives to eradicate chemoresistant cells in myeloid leukemia. Int J Mol Sci. 2021;22(5):2470. 10.3390/ijms22052470
   PubMed Web of Science ®Google Scholar
• Zhang H, Fang H, Wang K. Reactive oxygen species in eradicating acute myeloid leukemic stem cells. Stem Cell Investig. 2014;1:13.
   PubMedGoogle Scholar
• Starkova J, Hermanova I, Hlozkova K, Hararova A, Trka J. Altered metabolism of leukemic cells: new therapeutic opportunity. Int Rev Cell Mol Biol. 2018;336:93–147. 10.1016/bs.ircmb.2017.07.012
   PubMed Web of Science ®Google Scholar
• Betteridge DJ. What is oxidative stress? Metabolism. 2000;49(2):3–8. 10.1016/s0026-0495(00)80077-3
   PubMed Web of Science ®Google Scholar
• De Maria N, Colantonl A, Fagiuoli S, Liu G-J, Rogers BK, Farinati F, et al. Association between reactive oxygen species and disease activity in chronic hepatitis C. Free Radical Biol Med. 1996;21(3):291–5.
   PubMed Web of Science ®Google Scholar
• Ghasemi H, Amini MA, Pegah A, Azizi E, Tayebinia H, Khanverdilou S, Mousavibahar SH, Alizamir A. Overexpression of reactive oxygen species modulator 1 is associated with advanced grades of bladder cancer. Mol Biol Rep. 2020;47(9):6497–505.
   PubMed Web of Science ®Google Scholar
• Zuo XL, Chen JM, Zhou X, Li XZ, Mei GY. Levels of selenium, zinc, copper, and antioxidant enzyme activity in patients with leukemia. Biol Trace Elem Res. 2006;114(1–3):41–53.
   PubMed Web of Science ®Google Scholar
• Ng SH. Characterization of colon cancer cell culture based screening assay to study effects of phenolic acids [Doctoral dissertation]. Saskatoon: University of Saskatchewan; 2011.
   Google Scholar
• Shibanuma M, Kuroki T, Nose K. Superoxide as a signal for increase in intracellular pH. J Cell Physiol. 1988;136(2):379–83. 10.1002/jcp.1041360224
   PubMed Web of Science ®Google Scholar
• Assady M, Farahnak A, Golestani A, Esharghian M. Superoxide dismutase (SOD) enzyme activity assay in Fasciola spp. parasites and liver tissue extract. Iran J Parasitol. 2011;6(4):17–22.
   PubMed Web of Science ®Google Scholar
• Hole PS, Zabkiewicz J, Munje C, Newton Z, Pearn L, White P, Marquez N, Hills RK, Burnett AK, Tonks A, et al. Overproduction of NOX-derived ROS in AML promotes proliferation and is associated with defective oxidative stress signaling. Blood. 2013;122(19):3322–30.
   PubMed Web of Science ®Google Scholar
• Rahman MM, Islam MB, Biswas M, Khurshid Alam AHM. In vitro antioxidant and free radical scavenging activity of different parts of Tabebuia pallida growing in Bangladesh. BMC Res Notes. 2015;8(1):621. 10.1186/s13104-015-1618-6
   PubMedGoogle Scholar
• Fresco P, Borges F, Diniz C, Marques MP. New insights on the anticancer properties of dietary polyphenols. Med Res Rev. 2006;26(6):747–66. 10.1002/med.20060
   PubMed Web of Science ®Google Scholar
• Ghasemzadeh Rahbardar M, Hosseinzadeh H. Therapeutic effects of rosemary (Rosmarinus officinalis L.) and its active constituents on nervous system disorders. Iran J Basic Med Sci. 2020;23(9):1100–12.
   PubMed Web of Science ®Google Scholar
• Albasher G, Albrahim T, Aljarba N, Alharbi RI, Alsultan N, Alsaiari J, Rizwana H. Involvement of redox status and the nuclear-related factor 2 in protecting against cadmium-induced renal injury with Sana Makki (Cassia senna L.) pre-treatment in male rats. An Acad Bras Cienc. 2020;92(2):e20191237.
   PubMed Web of Science ®Google Scholar
• Srinivasulu C, Ramgopal M, Ramanjaneyulu G, Anuradha CM, Suresh Kumar C. Syringic acid (SA)‒a review of its occurrence, biosynthesis, pharmacological and industrial importance. Biomed Pharmacother. 2018;108:547–57. 10.1016/j.biopha.2018.09.069
   PubMed Web of Science ®Google Scholar
• Karamać M, Kosińska A, Pegg RB. Comparison of radical-scavenging activities for selected phenolic acids. Pol J Food Nutr Sci. 2005;55(2):165–70.
   Google Scholar
• Kampa M, Alexaki V-I, Notas G, Nifli A-P, Nistikaki A, Hatzoglou A, Bakogeorgou E, Kouimtzoglou E, Blekas G, Boskou D, et al. Antiproliferative and apoptotic effects of selective phenolic acids on T47D human breast cancer cells: potential mechanisms of action. Breast Cancer Res. 2004;6(2):R63–12. 10.1186/bcr752
   PubMed Web of Science ®Google Scholar
• Zhang L, Liu R, Niu W. Phytochemical and Antiproliferative Activity of Proso Millet. PLoS One. 2014;9(8):e104058. 10.1371/journal.pone.0104058
   PubMed Web of Science ®Google Scholar
• Cheemanapalli S, Anuradha C, Madhusudhana P, Mahesh M, Raghavendra P, S, Kumar C. Exploring the binding affinity of novel syringic acid analogues and critical determinants of selectivity as potent proteasome inhibitors. Anti-Cancer Agents Med Chem. 2016;16(11):1496–510.
   PubMed Web of Science ®Google Scholar
• Ha SJ, Lee J, Park J, Kim YH, Lee NH, Kim YE, Song K-M, Chang P-S, Jeong C-H, Jung SK, et al. Syringic acid prevents skin carcinogenesis via regulation of NoX and EGFR signaling. Biochem Pharmacol. 2018;154:435–45.
   PubMed Web of Science ®Google Scholar
• Abotaleb M, Liskova A, Kubatka P, Büsselberg D. Therapeutic potential of plant phenolic acids in the treatment of cancer. Biomolecules. 2020;10(2):221. 10.3390/biom10020221
   PubMed Web of Science ®Google Scholar
• Pei J, Velu P, Zareian M, Feng Z, Vijayalakshmi A. Effects of syringic acid on apoptosis, inflammation, and AKT/mTOR signaling pathway in gastric cancer cells. Front Nutr. 2021;8:788929 10.3389/fnut.2021.788929
   PubMed Web of Science ®Google Scholar
• Yang N, Qiu F, Zhu F, Qi L. Therapeutic potential of zinc oxide-loaded syringic acid against in vitro and in vivo model of lung cancer. Int J Nanomed. 2020;15:8249–60. 10.2147/IJN.S272997
   PubMed Web of Science ®Google Scholar
• Mihanfar A, Darband SG, Sadighparvar S, Kaviani M, Mirza-Aghazadeh-Attari M, Yousefi B, Majidinia M. In vitro and in vivo anticancer effects of syringic acid on colorectal cancer: possible mechanistic view. Chem Biol Interact. 2021;337:109337.
   PubMed Web of Science ®Google Scholar
• Haagen L, Brock A. A new automated method for phenotyping arylesterase (EC 3.1. 1.2) based upon inhibition of enzymatic hydrolysis of 4-nitrophenyl acetate by phenyl acetate. 1992.
   Google Scholar
• Satoh K. Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method. Clin Chim Acta. 1978;90(1):37–43. 10.1016/0009-8981(78)90081-5
   PubMed Web of Science ®Google Scholar
• Evans P, Lyras L, Halliwell B. Measurement of protein carbonyls in human brain tissue. In: Methods in enzymology. Vol. 300. Academic Press; 1999. p. 145–56.
   Google Scholar
• Benzie IFF, Strain JJ. The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: the FRAP assay. Anal Biochem. 1996;239(1):70–6.
   PubMed Web of Science ®Google Scholar
• Battisti V, Maders LDK, Bagatini MD, Santos KF, Spanevello RM, Maldonado PA, Brulé AO, Araújo MdC, Schetinger MRC, Morsch VM, et al. Measurement of oxidative stress and antioxidant status in acute lymphoblastic leukemia patients. Clin Biochem. 2008;41(7-8):511–8.
   PubMed Web of Science ®Google Scholar
• Farquhar MJ, Bowen DT. Oxidative stress and the myelodysplastic syndromes. Int J Hematol. 2003;77(4):342–50. 10.1007/BF02982641
   PubMed Web of Science ®Google Scholar
• Sallmyr A, Fan J, Rassool F. Genomic instability in myeloid malignancies: Increased reactive oxygen species (ROS), DNA double strand breaks (DSBs) and error-prone repair. Cancer Lett. 2008;270(1):1–9. 10.1016/j.canlet.2008.03.036
   PubMed Web of Science ®Google Scholar
• Abaza M-S, Ra A-A, Bhardwaj R, Abbadi G, Koyippally M, Afzal M. Syringic acid from Tamarix aucheriana possesses antimitogenic and chemo-sensitizing activities in human colorectal cancer cells. Pharm Biol. 2013;51(9):1110–24.
   PubMed Web of Science ®Google Scholar
• Orabi KY, Abaza MS, El Sayed KA, Elnagar AY, Al-Attiyah R, Guleri RP. Selective growth inhibition of human malignant melanoma cells by syringic acid-derived proteasome inhibitors. Cancer Cell Int. 2013;13(1):82–16. 10.1186/1475-2867-13-82
   PubMedGoogle Scholar
• Pujari KN, Jadkar SP, Patil CG, Kulkarni A, Tuljapurkar VB. Variations in serum malondialdehyde levels in patients with leukemia. Int J Clin Biochem Res. 2018;5(2):254–6.
   Google Scholar
• Liu J, Wang W, Chen L, Li Y, Zhao S, Liang Y. Chemoprotective effect of syringic acid on cyclophosphamide induced ovarian damage via inflammatory pathway. J Oleo Sci. 2021;70(5):675–83.
   PubMed Web of Science ®Google Scholar
• Güven M, Aras AB, Topaloğlu N, Özkan A, Şen HM, Kalkan Y, Okuyucu A, Akbal A, Gökmen F, Coşar M, et al. The protective effect of syringic acid on ischemia injury in rat brain. Turk J Med Sci. 2015;45(1):233–40.
   PubMed Web of Science ®Google Scholar
• Dalmagro AP, Camargo A, Pedron NB, Garcia SAM, Zeni ALB. Morus nigra leaves extract revokes the depressive-like behavior, oxidative stress, and hippocampal damage induced by corticosterone: a pivotal role of the phenolic syringic acid. Behav Pharmacol. 2020;31(4):397–406. 10.1097/FBP.0000000000000549
   PubMed Web of Science ®Google Scholar
• Rajeshwari U, Iyer S, Raghunatha R, Andallu B. Oxidative stress and antioxidant status in acute and chronic myeloid leukemia patients. Open J Blood Dis. 2013;03(03):17–22. 10.4236/ojbd.2013.33A004
   Google Scholar
• Sabahi Z, Khoshnoud MJ, Hosseini S, Khoshraftar F, Rashedinia M. Syringic acid attenuates cardiomyopathy in streptozotocin-induced diabetic rats. Adv Pharmacol Pharm Sci. 2021;2021:5018092. 10.1155/2021/5018092
   PubMedGoogle Scholar
• Hole PS, Darley RL, Tonks A. Do reactive oxygen species play a role in myeloid leukemias? Blood. 2011;117(22):5816–26. 10.1182/blood-2011-01-326025
   PubMed Web of Science ®Google Scholar
• Cikman O, Soylemez O, Ozkan OF, Kiraz HA, Sayar I, Ademoglu S, Taysi S, Karaayvaz M. Antioxidant activity of syringic acid prevents oxidative stress in l-arginine-induced acute pancreatitis: an experimental study on rats. International surgery. 2015;100(5):891–6. 10.9738/INTSURG-D-14-00170.1
   PubMed Web of Science ®Google Scholar
• Sancak EB, Akbas A, Silan C, Cakir DU, Turkon H, Ozkanli SS. Protective effect of syringic acid on kidney ischemia-reperfusion injury. Ren Fail. 2016;38(4):629–35. 10.3109/0886022X.2016.1149868
   PubMed Web of Science ®Google Scholar
• Kökoğlu E, Aktuğlu G, Belce A. Leucocyte superoxide dismutase levels in acute and chronic leukemias. Leuk Res. 1989;13(6):457–8. 10.1016/0145-2126(89)90166-5
   PubMed Web of Science ®Google Scholar
• Sammeturi M, Shaik AH, Bongu SBR, Cheemanapalli S, Mohammad A, Kodidhela LD. Protective effects of syringic acid, resveratrol and their combination against isoprenaline administered cardiotoxicity in wistar rats. Saudi J Biol Sci. 2019;26(7):1429–35. 10.1016/j.sjbs.2019.09.027
   PubMed Web of Science ®Google Scholar
• Zhou J-D, Lin J, Zhang T-J, Ma J-C, Yang L, Wen X-M, Guo H, Yang J, Deng Z-Q, Qian J. GPX3 methylation in bone marrow predicts adverse prognosis and leukemia transformation in myelodysplastic syndrome. Cancer Med. 2017;6(1):267–74.
   PubMed Web of Science ®Google Scholar
• Kos Z, Pavelić L, Pekić B, Pavelić K. Reversal of human myeloid leukemia cells into normal granulocytes and macrophages: activity and intracellular distribution of catalase. Oncology. 1987;44(4):245–7. 10.1159/000226487
   PubMed Web of Science ®Google Scholar