Characterizing the Role of Calcium Sensing Receptor in the Progression of Obesity-Mediated Aggressive Prostate Cancer Phenotype

References

• Lauby-Secretan B, Scoccianti C, Loomis D, Grosse Y, Bianchini F, Straif K. Body fatness and cancer - viewpoint of the IARC working Group. N Engl J Med. 2016;375(8):794–8. 10.1056/NEJMsr1606602
   PubMed Web of Science ®Google Scholar
• Porter MP, Stanford JL. Obesity and the risk of prostate cancer. Prostate. 2005;62(4):316–21. doi:10.1002/pros.20121.
   PubMed Web of Science ®Google Scholar
• Allott EH, Masko EM, Freedland SJ. Obesity and prostate cancer: Weighing the evidence. Eur Urol. 2013;63(5):800–9. doi:10.1016/j.eururo.2012.11.013.
   PubMed Web of Science ®Google Scholar
• Hanahan D, Weinberg RA. Hallmarks of cancer: The next generation. Cell. 2011;144(5):646–74. doi:10.1016/j.cell.2011.02.013.
   PubMed Web of Science ®Google Scholar
• Donohoe CL, Lysaght J, O'Sullivan J, Reynolds JV. Emerging concepts linking obesity with the hallmarks of cancer. Trends Endocrinol Metab. 2017;28(1):46–62. doi:10.1016/j.tem.2016.08.004.
   PubMed Web of Science ®Google Scholar
• Pérez-Hernández AI, Catalán V, Gómez-Ambrosi J, Rodríguez A, Frühbeck G. Mechanisms linking excess adiposity and carcinogenesis promotion. Front Endocrinol (Lausanne). 2014;5:1–17. doi:10.3389/fendo.2014.00065.
   PubMed Web of Science ®Google Scholar
• Trulson MF, Clancy RE, Stare FJ. Advances in nutrition and dietetics. Practitioner. 1962;189:505–12. doi:10.1007/978-3-642-38007-5.
   PubMedGoogle Scholar
• Ribeiro RJT, Monteiro CPD, Cunha VFPM, Azevedo ASM, Oliveira MJ, Monteiro R, Fraga AM, Príncipe P, Lobato C, Lobo F, et al. Tumor cell-educated periprostatic adipose tissue acquires an aggressive cancer-promoting secretory profile. Cell Physiol Biochem. 2012;29(1-2):233–40. 10.1159/000337604
   PubMedGoogle Scholar
• Cao Y. Angiogenesis modulates adipogenesis and obesity. J Clin Invest. 2007;117(9):2362–8. doi:10.1172/JCI32239.
   PubMed Web of Science ®Google Scholar
• Sarkar P, Kumar S. Calcium sensing receptor modulation for cancer therapy. Asian Pac J Cancer Prev. 2012;13(8):3561–8. doi:10.7314/APJCP.2012.13.8.3561.
   PubMedGoogle Scholar
• Sanders JL, Chattopadhyay N, Kifor O, Yamaguchi T, Brown Em, Jennifer L. Ca2+-sensing receptor expression and PTHrP secretion in PC-3 human prostate cancer cells. 2001. 1267–1274.
   Google Scholar
• Chang W, Tu C, Chen TH, Bikle D, Shoback D. The extracellular calcium-sensing receptor (CaSR) is a critical modulator of skeletal development. Sci Signal. 2013;1(35):1–23. doi:10.1126/scisignal.1159945.
   Google Scholar
• Hobisch A, Eder IE, Putz T, et al. Interleukin-6 regulates prostate-specific protein expression in prostate carcinoma cells by activation of the androgen receptor. Cancer Res. 1998;58(20):4640–5.
   PubMed Web of Science ®Google Scholar
• Lee SO, Lou W, Hou M, De MF, Gerber L, Gao AC. Interleukin-6 promotes androgen-independent growth in LNCaP human prostate cancer cells. Clin Cancer Res. 2003;9(1):370–6.
   PubMed Web of Science ®Google Scholar
• Steiner H, Berger AP, Godoy-Tundidor S, Bjartell A, Lilja H, Bartsch G, Hobisch A, Culig Z. An autocrine loop for vascular endothelial growth factor is established in prostate cancer cells generated after prolonged treatment with interleukin 6. Eur J Cancer. 2004;40(7):1066–72. doi:10.1016/j.ejca.2003.11.033.
   PubMed Web of Science ®Google Scholar
• Giannoni E, Bianchini F, Masieri L, Serni S, Torre E, Calorini L, Chiarugi P. Reciprocal activation of prostate cancer cells and cancer-associated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemness. Cancer Res. 2010;70(17):6945–56. doi:10.1158/0008-5472.CAN-10-0785.
   PubMed Web of Science ®Google Scholar
• Garg R, Blando J, Perez CJ, Wang H, Benavides FJ, Kazanietz MG. Activation of nuclear factor κB (NF-κB) in prostate cancer Is mediated by protein kinase Cε (PKCε). J Biol Chem. 2012;287(44):37570–82. doi:10.1074/jbc.M112.398925.
   PubMed Web of Science ®Google Scholar
• Font-Burgada J, Sun B, Karin M. Obesity and cancer: The oil that feeds the flame. Cell Metab. 2016;23(1):48–62. doi:10.1016/j.cmet.2015.12.015.
   PubMed Web of Science ®Google Scholar
• Smith WL, DeWitt DL, Garavito RM. Cyclooxygenases: Structural, cellular, and molecular biology. Annu Rev Biochem. 2000;69(1):145–82. doi:10.1146/annurev.biochem.69.1.145.
   PubMedGoogle Scholar
• Bieniek J, Childress C, Swatski MD, Yang W. COX-2 inhibitors arrest prostate cancer cell cycle progression by down-regulation of kinetochore/centromere proteins. Prostate. 2014;74(10):999–1011. doi:10.1002/pros.22815.
   PubMed Web of Science ®Google Scholar
• World Cancer Research Fund. Diet, nutrition, physical activity and prostate cancer. 2014. 50. http://www.wcrf.org/sites/default/files/Prostate-Cancer-2014-Report.pdf.
   Google Scholar
• Binder M, Shui IM, Wilson KM, Penney KL, Mucci LA, Kibel AS, PRACTICAL/ELLIPSE Consortium Calcium intake, polymorphisms of the calcium-sensing receptor, and recurrent/aggressive prostate cancer. Cancer Causes Control. 2015;26(12):1751–9. 10.1007/s10552-015-0668-3
   PubMed Web of Science ®Google Scholar
• Bernichtein S, Pigat N, Barry Delongchamps N, Boutillon F, Verkarre V, Camparo P, Reyes-Gomez E, Méjean A, Oudard SM, Lepicard EM, et al. Vitamin D3 prevents calcium-induced progression of early-stage prostate tumors by counteracting TRPC6 and calcium sensing receptor upregulation. Cancer Res. 2017;77(2):355–65. doi:10.1158/0008-5472.CAN-16-0687.
   PubMed Web of Science ®Google Scholar
• Chakravarti B, Dwivedi SKD, Mithal A, Chattopadhyay N. Calcium-sensing receptor in cancer: Good cop or bad cop? Endocrine. 2009;35(3):271–84. doi:10.1007/s12020-008-9131-5.
   PubMed Web of Science ®Google Scholar
• Ahearn TU, Tchrakian N, Wilson KM, Lis R, Nuttall E, Sesso HD, Loda M, Giovannucci E, Mucci LA, Finn S, et al. Calcium-sensing receptor tumor expression and lethal prostate cancer progression. J Clin Endocrinol Metab. 2016;101(6):2520–7. doi:10.1210/jc.2016-1082.
   PubMed Web of Science ®Google Scholar
• Feng J, Xu X, Li B, et al. Prostate cancer metastatic to bone has higher expression of the calcium-sensing receptor (CaSR) than primary prostate cancer. Recept Clin Investig. 2015;1(6):1–14. doi:10.14800/rci.270.
   Google Scholar
• Kameda T, Mano H, Yamada Y, Takai H, Amizuka N, Kobori M, Izumi N, Kawashima H, Ozawa H, Ikeda K, et al. Calcium-sensing receptor in mature osteoclasts, which are bone resorbing cells. Biochem Biophys Res Commun. 1998;245(2):419–22. doi:10.1006/bbrc.1998.8448.
   PubMed Web of Science ®Google Scholar
• Sanders JL, Chattopadhyay N, et al. Extracellular calcium-sensing receptor expression and its potential role in regulating parathyroid hormone related peptide secretion in human breast cancer. Endo. 2015;141(12):0–7.
   Google Scholar
• Yano S, Macleod RJ, Chattopadhyay N, Tfelt-Hansen J, Kifor O, Butters RR, Brown EM. Calcium-sensing receptor activation stimulates parathyroid hormone-related protein secretion in prostate cancer cells: Role of epidermal growth factor receptor transactivation. Bone. 2004;35(3):664–72. doi:10.1016/j.bone.2004.04.014.
   PubMed Web of Science ®Google Scholar
• Canaff L, Zhou X, Hendy GN. The proinflammatory cytokine, interleukin-6, up-regulates calcium-sensing receptor gene transcription via Stat1/3 and Sp1/3. J Biol Chem. 2008;283(20):13586–600. doi:10.1074/jbc.M708087200.
   PubMed Web of Science ®Google Scholar
• Canaff L, Hendy GN. Calcium-sensing receptor gene transcription is up-regulated by the proinflammatory cytokine, interleukin-1β: Role of the NF-κB pathway and κB elements. J Biol Chem. 2005;280(14):14177–88. doi:10.1074/jbc.M408587200.
   PubMed Web of Science ®Google Scholar
• Cifuentes M, Fuentes C, Mattar P, Tobar N, Hugo E, Ben-Jonathan N, Rojas C, Martínez J. Obesity-associated proinflammatory cytokines increase calcium sensing receptor (CaSR) protein expression in primary human adipocytes and LS14 human adipose cell line. Arch Biochem Biophys. 2010;500(2):151–6. doi:10.1016/j.abb.2010.05.033.
   PubMed Web of Science ®Google Scholar
• Déliot N, Constantin B. Plasma membrane calcium channels in cancer: alterations and consequences for cell proliferation and migration. Biochim Biophys Acta. 2015;1848(10 Pt B):2512–22. doi:10.1016/j.bbamem.2015.06.009.
   PubMed Web of Science ®Google Scholar
• Miethe C, Nix H, Martin R, Hernandez AR, Price RS. Silibinin reduces the impact of obesity on invasive liver cancer. Nutr Cancer. 2017;69(8):1272–80. doi:10.1080/01635581.2017.1367935.
   PubMed Web of Science ®Google Scholar
• Price RS, Cavazos D a, De Angel RE, Hursting SD, deGraffenried L. Obesity-related systemic factors promote an invasive phenotype in prostate cancer cells. Prostate Cancer Prostatic Dis. 2012;15(2):135–43. doi:10.1038/pcan.2011.54.
   PubMed Web of Science ®Google Scholar
• Giovannucci E, Pollak M, Liu Y, Platz EA, Majeed N, Rimm EB, Willett WC. Nutritional predictors of insulin-like growth factor 1 and their relationships to cancer in men. Cancer Epidemiol Biomarkers Prev. 2003;12(2):84–9.
   PubMed Web of Science ®Google Scholar
• Rodriguez C, McCullough ML, Mondul AM, et al. Calcium, dairy products, and risk of prostate cancer in a prospective cohort of United States men. Cancer Epidemiol Biomarkers Prev. 2003;12(7):597–603.
   PubMed Web of Science ®Google Scholar
• Lokeshwar BL, Schwartz GG, Selzer MG, Burnstein KL, Zhuang SH, Block NL, Binderup L. Inhibition of prostate cancer metastasis in vivo: a comparison of 1,23-dihydroxyvitamin D (calcitriol) and EB1089. Cancer Epidemiol Biomarkers Prev. 1999;8(3):241–8.
   PubMed Web of Science ®Google Scholar