Retardation of experimental oral cancer by topical vitamin E

References and notes

• Harman , D . 1969 . “Dimethylbenzanthracene‐Induced Cancer. Inhibiting Effect of Dietary Vitamin E” . Clin Res , 17 : 125 – 129 .
   Google Scholar
• Slaga , TJ and Bracken , WM . 1977 . “The Effects of Antioxidants on Skin Tumor Initiation and Aryl Hydrocarbon Hydroxylase” . Cancer Res , 37 : 1631 – 1635 .
   PubMed Web of Science ®Google Scholar
• Cook , MG and McNamara , P . 1980 . “Effect of Dietary Vitamin E on Dimethylhydrazine‐Induced Colonic Tumors in Mice” . Cancer Res , 40 : 1329 – 1332 .
   PubMed Web of Science ®Google Scholar
• Shklar , G . 1982 . “Oral Mucosal Carcinogenesis in Hamsters: Inhibition by Vitamin E” . JNCI , 68 : 791 – 797 .
   PubMed Web of Science ®Google Scholar
• Weerapradist , W and Shklar , G . 1982 . “Vitamin E Inhibition of Hamster Buccal Pouch Carcinogenesis: A Gross, Histologic and Ultrastructural Study” . Oral Surg , 54 : 304 – 312 .
   PubMedGoogle Scholar
• Salley , JJ . 1954 . “Experimental Carcinogenesis in the Cheek Pouch of the Syrian Hamster” . J Dent Res , 33 : 243 – 262 .
   Google Scholar
• Shklar , G . 1972 . “Experimental Oral Pathology in the Syrian Hamster” . Prog Exp Tumor Res , 16 : 518 – 538 .
   PubMed Web of Science ®Google Scholar
• Bartlett , GL , Krieder , JW and Parnell , DM . 1976 . “Immunotherapy of Cancer in Animals: Models or Muddles” . JNCI , 56 : 207 – 210 .
   PubMedGoogle Scholar
• Osborne , MR . 1979 . “Diolepoxides—The Key to Hydrocarbon Carcinogenesis?” . Trends Biochem Sci , 4 : 213 – 215 .
   Google Scholar
• Tappel , AL . 1972 . “Vitamin E and Free Radical Peroxidation of Lipids” . Ann NY Acad Sci , 230 : 12 – 28 .
   Web of Science ®Google Scholar
• Tinberg , HM and Barber , AA . 1970 . “Studies on Vitamin E Action: Peroxidation Inhibition in Structural Protein Lipid Micelle Complexes Derived From Rat Liver Microsomal Membranes” . J Nutr , 100 : 413 – 418 .
   PubMedGoogle Scholar
• Molenaar , I , Vos , J , Jager , FC and Hommes , FA . 1970 . “The Influence of Vitamin E Deficiency on Biological Membranes: An Ultrastructural Study on the Intestinal Epithelial Cells of Ducklings” . Nutr Metab , 12 : 358 – 370 .
   PubMedGoogle Scholar
• McCay , PB , Poyer , JL , Pfeifer , PM , May , HE and Gilliam , JM . 1971 . “A Function of α‐Tocopherol: Stabilization of the Microsomal Membrane From Radical Attack During TPNH‐Dependent Oxidations” . Lipids , 6 : 297 – 306 .
   Web of Science ®Google Scholar
• Schwartz , J , Solt , DB , Pappo , J and Weichselbaum , R . 1981 . “Distribution of Langerhans’ Cells in Normal and Carcinogen Treated Mucosa of Buccal Pouches of Hamsters” . J Dermatol Surg Oncol , 7 : 1005 – 1010 .
   PubMedGoogle Scholar
• Schwartz, J, Odukoya, O, Stoufi, E, Shklar, G: “Alpha Tocopherol Alters the Distribution of Langerhans’ Cells in DMBA‐Treated Hamster Pouch Epithelium” (in preparation)
   Google Scholar
• Stingl , G . 1978 . “Analogous Expression of Macrophages and Langerhans’ Cells in the Initiation of the Immune Response” . J Invest Dermatol , 71 : 59 – 64 .
   PubMedGoogle Scholar
• Streilein , JW and Bergstresser , PR . 1981 . “Langherhans’ Cell Function Dictates Induction of Contact Hypersen‐sitivity of Unresponsiveness to DMBA in Syrian Hamsters” . J Invest Dermatol , 11 : 272 – 277 .
   Google Scholar
• This research received support from grant no. 0004–02 of the Smokeless Tobacco Research Council, Inc., New York.
   Google Scholar