References
- Neiderau , C , Fischer , R , Sonnenberg , A , Stremmel , W Trampisch , HJ . 1985 . “Survival and Causes of Death in Cirrhotic and Noncirrhotic Patients With Primary Hemochromatosis” . N Engl J Med , 313 : 1256 – 1262 .
- Salata , H , Cortes , JM , Salamanca , RE , Oliva , H Castro , A . 1985 . “Porphyria Cutanea Tarda and Hepatocellular Carcinoma” . J Hepatol , 1 : 477 – 487 .
- Selby , JV and Friedman , GD . 1988 . “Epidemiologic Evidence of an Association Between Body Iron Stores and Risk of Cancer” . Int J Cancer , 41 : 677 – 682 .
- Stevens , RG , Beasley , RP and Blumberg , BS . 1986 . “Iron‐Binding Proteins and Risk of Cancer in Taiwan” . JNCI , 76 : 605 – 610 .
- Jacobs , A . 1980 . “The Pathology of Iron Overload” . In Iron in Biochemistry and Medicine, II , Edited by: Jacobs , A and Worwood , M . 427 – 459 . New York : Academic .
- Aust , SD , Chignell , CF , Bray , TM , Kalyanaraman , B and Mason , RP . 1993 . “Contemporary Issues in Toxicology, Free Radicals in Toxicology” . Toxicol Appl Pharmacol , 120 : 168 – 178 .
- Fenton , HJH . 1894 . “Oxidation of Tartaric Acid in Presence of Iron” . J Chem Soc , 65 : 899 – 910 .
- Haber , F and Weiss , J . 1934 . “The Catalytic Decomposition of Hydrogen Peroxide by Iron Salts” . Proc R Soc Lond Ser A , 147 : 332 – 351 .
- Bolann , BJ and Ulvik , RJ . 1990 . “On the Limited Ability of Superoxide to Release Iron From Ferritin” . Eur J Biochem , 193 : 899 – 904 .
- 1988 . “Free Radicals and Antioxidant Protection: Mechanisms and Significance in Toxicology and Disease” (editorial) . Hum Toxicol , 7 : 7 – 13 .
- Ames , BN . 1983 . “Dietary Carcinogens and Anticarcinogens” . Science , 221 : 1256 – 1264 .
- Burton , GW . 1989 . “Antioxidant Action of Carotenoids” . J Nutr , 119 : 109 – 111 .
- Dillard , CJ , Downey , JE and Tappel , AL . 1984 . “Effect of Antioxidants on Lipid Peroxidation in Iron‐Loaded Rats” . Lipids , 19 : 127 – 132 .
- Stocker , R and Ames , BN . 1987 . “Potential Role of Conjugated Bilirubin and Copper in the Metabolism of Lipid Peroxides in Bile” . Proc Natl Acad Sci USA , 84 : 8130 – 8134 .
- Burton , GW and Ingold , KU . 1984 . “β‐Carotene: an Unusual Type of Lipid Antioxidant” . Science , 224 : 569 – 573 .
- Santamaria , L , Bianchi , A , Arnaboldi , A , Ravetto , C Bianchi , L . 1988 . “Chemoprevention of Indirect and Direct Chemical Carcinogenesis by Carotenoids as Oxygen Radical Quenchers” . Ann NY Acad Sci , 534 : 584 – 596 .
- Shklar , G , Schwartz , J , Trickier , D and Reid , S . 1989 . “Regression of Experimental Cancer by Oral Administration of Combined Alpha‐Tocopherol and Beta‐Carotene” . Nutr Cancer , 12 : 321 – 325 .
- Tim , KI . 1979 . “Orbital Venous Anatomy of the Rat” . Lab Anim Sci , 29 : 636 – 638 .
- Crosby , WH and Munn , SI . 1954 . “Standardized Method for Clinical Hemoglobinometry” . US Armed Forces Med J , 51 : 693 – 703 .
- Whittaker , P and Vanderveen , JE . 1990 . “Effect of EDTA on the Bioavailability of Fortification Iron Used in Egyptian Balady Bread” . Br J Nutr , 63 : 587 – 595 .
- Watson , BD , Busto , R , Goldberg , WJ , Santiso , M Yoshida , S . 1984 . “Lipid Peroxidation In Vivo Induced by Reversible Global Ischemia in Rat Brain” . J Neurochem , 42 : 268 – 274 .
- Folch , J , Lees , M and Sloane , GH . 1957 . “A Simple Method for the Isolation and Purification of Total Lipids From Animal Tissues” . J Biol Chem , 226 : 497 – 509 .
- ABstat . 1993 . ABstat User Manual , Parker, CO : Anderson‐Bell . Version 7.02.
- Snedecor , GW and Cochran , WG . 1980 . Statistical Methods , 175 – 193 . 215 – 237 . Ames, IA : Iowa State University Press .
- Whittaker , P , Wamer , W and Calvert , RJ . 1992 . “Effect of Chronic Iron Overload on Iron Status, Lipid Peroxidation, Cell Proliferation, and DNA Damage” . J Trace Elem Exp Med , 5 : 227 – 236 .
- Whittaker , P , Chanderbhan , R , Calvert , R and Dunkel , V . 1994 . “Cellular and Molecular Responses in the Sprague‐Dawley Rat to Chronic Iron Overload” . J Trace Elem Exp Med , 7 : 19 – 31 .
- Umegaki , K , Takeuchi , N , Ikegami , S and Ichikawa , T . 1994 . “Effect of β‐Carotene on Spontaneous and X‐Ray‐Induced Chromosomal Damage in Bone Marrow Cells of Mice” . Nutr Cancer , 22 : 277 – 284 .
- Bendich , A and Shapiro , SS . 1986 . “Effect of β‐Carotene and Canthaxanthin on the Immune Responses of the Rat” . J Nutr , 116 : 2254 – 2262 .
- Mobarhan , S , Shiau , A , Grande , A , Kolli , S Stacewicz‐Sapuntzakis , M . 1994 . “β‐Carotene Supplementation Results in an Increased Serum and Colonic Mucosal Concentration of β‐Carotene and a Decrease in α‐Tocopherol Concentration in Patients With Colonic Neoplasia” . Cancer Epidemiol Biomarkers Prev , 3 : 501 – 505 .
- Whittaker , P and Chanderbhan , R . 1993 . “Effects of Increasing Iron Supplementation on Serum Free Fatty Acids, Phospholipids and Cholesterol” (abstr) . FASEB J , 7 : 297
- Dabbagh , AJ , Mannion , T , Lynch , SM and Frei , B . 1994 . “The Effect of Iron Overload on Rat Plasma and Liver Oxidant Status” . In Vivo Biochem J , 300 : 799 – 803 .