19
Views
21
CrossRef citations to date
0
Altmetric
Reports

In vitro β‐carotene toxicity for human colon cancer cells

, , &
Pages 221-230 | Received 17 Oct 1995, Accepted 27 Dec 1995, Published online: 04 Aug 2009

References

  • Ziegler , RG . 1989 . “A Review of Epidemiological Evidence That Carotenoids Reduce the Risk of Cancer” . J Nutr , 119 : 116 – 122 .
  • Wald , NJ , Thompson , SG , Densem , JW , Boreham , J and Bailey , A . 1988 . “Serum Beta‐Carotene and Subsequent Risk of Cancer: Results From the BUPA Study” . Br J Cancer , 57 : 428 – 433 .
  • Kneller , RW , Guo , WD , Hsing , AW , Chen , JS Blot , WJ . 1992 . “Risk Factors for Stomach Cancer in Sixty‐Five Chinese Counties” . Cancer Epidemiol Biomarkers Prev , 1 : 113 – 118 .
  • Singh , VN and Gaby , SK . 1991 . “Premalignant Lesions: Role of Antioxidant Vitamins and β‐Carotene in Risk Reduction and Prevention of Malignant Transformation” . Am J Clin Nutr , 53 : 386S – 390S .
  • Alpha‐Tocopherol, Beta‐Carotene Cancer Prevention Study Group . 1994 . “The Effect of Vitamin E and Beta‐Carotene on the Incidence of Lung Cancer and Other Cancers in Male Smokers” . N Engl J Med , 330 : 1029 – 1035 .
  • Greenberg , ER , Baron , JA , Tosteson , TD , Freeman , DH Beck , GJ . 1994 . “A Clinical Trial of Antioxidant Vitamins to Prevent Colorectal Adenoma” . N Engl J Med , 331 : 141 – 147 .
  • Cahill , RJ , O'Sullivan , KR , Mathias , PM , Beattie , S Hamilton , H . 1993 . “Effects of Vitamin Antioxidant Supplementation on Cell Kinetics of Patients With Adenomatous Polyps” . Gut , 34 : 963 – 967 .
  • Murata , T , Tamai , H , Morinobu , T , Manago , M Takenaka , H . 1994 . “Effect of Long‐Term Administration of β‐Carotene on Lymphocyte Subsets in Humans” . Am J Clin Nutr , 60 : 597 – 602 .
  • Schwartz , J and Shklar , G . 1992 . “The Selective Effect of Carotenoids and α‐Tocopherol on Human Cancer Cell Lines In Vitro” . J Oral Maxillofac Surg , 50 : 367 – 373 .
  • Nierenberg , DW , Stukal , TA , Baron , JA , Dain , BS and Greenberg , ER . 1991 . “Determinants of Increase in Plasma Concentrations of β‐Carotene After Chronic Oral Supplementation” . Am J Clin Nutr , 53 : 1443 – 1449 .
  • Rock , CL , Kusluski , RA , Galvez , MM and Ethier , SP . 1995 . “Carotenoids Induce Morphological Changes in Human Mammary Epithelial Cell Cultures” . Nutr Cancer , 23 : 319 – 333 .
  • Pung , A , Rundhaug , JE , Yoshizawa , CN and Bertram , JS . 1988 . “β‐Carotene and Canthaxanthin Inhibit Chemically and Physically Induced Neoplastic Transformation in 10T1/2 Cells” . Carcinogenesis , 9 : 1533 – 1539 .
  • Schwartz , JL , Tanaka , J , Khandekar , V , Herman , TS and Teicher , BA . 1992 . “β‐Carotene and/or Vitamin ? as Modulators of Alkylating Agents in SCC‐25 Human Squamous Carcinoma Cells” . Cancer Chemother Pharmacol , 29 : 207 – 213 .
  • Krinsky , N . 1989 . “Carotenoids and Cancer in Animal Models” . J Nutr , 119 : 123 – 126 .
  • Constantino , JP , Kuller , LH , Begg , L , Redmond , CK and Bates , MW . 1988 . “Serum Level Changes After Administration of a Pharmacologic Dose of β‐Carotene” . Am J Clin Nutr , 48 : 1277 – 1283 .
  • Mobarhan , S , Shiau , A , Grande , A , Kolli , S Stacewicz‐Sapuntzakis , M . 1994 . “β‐Carotene Supplementation Results in an Increased Serum and Colonic Mucosal Concentration of β‐Carotene and a Decrease in α‐Tocopherol Concentration in Patients With Colonic Neoplasia” . Cancer Epidemiol Biomarkers Prev , 3 : 501 – 505 .
  • Pauwels , R , Balzarini , J , Baba , M , Snoeck , R Schols , D . 1988 . “Rapid and Automated Tetrazolium‐Based Colorimetric Assay for the Detection of Anti‐HIV Compounds” . J Virol Meth , 20 : 309 – 321 .
  • Bendich , A . 1988 . “The Safety of Beta‐Carotene” . Nutr Cancer , 11 : 207 – 214 .
  • Bertram , JS , Pung , AO , Churley , M , Kappock , TJ Wilkins , LR . 1991 . “Diverse Carotenoids Protect Against Chemically Induced Neoplastic Transformation” . Carcinogenesis , 12 : 671 – 678 .
  • Tang , G , Shiau , A , Russell , RM and Mobarhan , S . 1995 . “Serum Retinoic Acid Levels in Patients With Resected Benign and Malignant Colonic Neoplasias on β‐Carotene Supplementation” . Nutr Cancer , 23 : 291 – 298 .
  • DeLuca , LM . 1991 . “Retinoids and Their Receptors in Differentiation, Embryogenesis and Neoplasia” . FASEB J , 5 : 2924 – 2933 .
  • Frommel , TO , Coon , JS , Tsuruo , T and Robinson , IB . 1993 . “Variable Effects of Sodium Butyrate on the Expression and Function of the MDR1 (P‐Glycoprotein) Gene in Colon Carcinoma Cells” . Int J Cancer , 55 : 297 – 302 .
  • Bowry , VW , Ingold , KU and Stocker , R . 1992 . “Vitamin E in Human Low‐Density Lipoprotein” . Biochem J , 288 : 341 – 344 .
  • Hazuka , MB , Edwards‐Prasad , J , Newman , F , Kinzie , JJ and Prasad , KN . 1990 . “β‐Carotene Induces Morphological Differentiation and Decreases Adenylate Cyclase Activity in Melanoma Cells in Culture” . J Am Coll Nutr , 9 : 143 – 149 .
  • Frommel , TO , Mobarhan , S , Doria , M , Halline , AG Luk , GD . 1995 . “Effect of β‐Carotene Supplementation on Indices of Colonic Cell Proliferation” . JNCI , 87 : 1781 – 1787 .
  • Maini , G , Pappalardo , G , Ferro‐Luzzi , A , Raguzzini , A Azzini , E . 1995 . “Accumulation of β‐Carotene in Normal Colorectal Mucosa and Colonic Neoplastic Lesions in Humans” . Nutr Cancer , 24 : 23 – 31 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.