74
Views
56
CrossRef citations to date
0
Altmetric
Reports

S‐allyl cysteine inhibits nitrosomorpholine formation and bioactivation

, &
Pages 1-6 | Received 25 Nov 1996, Accepted 12 Feb 1997, Published online: 04 Aug 2009

References

  • Block , E . 1992 . “The organosulfur chemistry of the genus Allium—implications for the organic chemistry of sulfur” . Agnew Chem Int Ed Engl , 31 : 1135 – 1178 .
  • Mei , X , Wang , ML , Xu , HX , Pan , XY Gao , CY . 1982 . “Garlic and gastric cancer. I. The influence of garlic on the level of nitrate and nitrite in gastric juice” . Acta Nutr Sing , 4 : 53 – 56 .
  • You , WC , Blot , WJ , Chang , YS , Ershow , A Yang , ZT . 1989 . “Allium vegetables and reduced risk of stomach cancer” . JNCI , 81 : 162 – 164 .
  • Steinmetz , KA , Kushi , LH , Bostick , RM , Folsom , AR and Potter , JD . 1994 . “Vegetables, fruit, and colon cancer in the Iowa Women's Health Study” . Am J Epidemiol , 139 : 1 – 15 .
  • Dorant , E , Van den Brandt , PA and Goldbohm , RA . 1996 . “A prospective cohort study on the relationship between onion and leek consumption. garlic supplement use and the risk of colorectal carcinoma in The Netherlands” . Carcinogenesis , 17 : 477 – 484 .
  • Rao , AR , Sadhana , AS and Goel , HC . 1990 . “Inhibition of skin tumors in DMBA‐induced complete carcinogenesis system in mice by garlic (Allium sativum)” . Indian J Exp Biol , 28 : 405 – 408 .
  • Wargovich , MJ , Woods , C , Eng , VWS , Stevens , LC and Gary , KN . 1988 . “Chemoprevention of nitroso‐methylbenzylamine‐induced esophageal cancer in rats by the thioether, diallyl sulfide” . Cancer Res , 48 : 6872 – 6875 .
  • Liu , JZ , Lin , RI and Milner , JA . 1992 . “Inhibition of 7,12‐dimethylbenz(a)‐anthracene induced mammary tumors and DNA adducts by garlic powder” . Carcinogenesis , 13 : 1847 – 1851 .
  • Ip , C , Lisk , DJ and Stoewsand , GS . 1992 . “Mammary cancer prevention by regular garlic and selenium‐enriched garlic” . Nutr Cancer , 17 : 279 – 286 .
  • Schaffer , EM , Liu , JZ , Green , J , Dangler , CA and Milner , JA . 1996 . “Garlic and associated allyl sulfur components inhibit N‐methyl‐N‐nitrosourea induced rat mammary carcinogenesis” . Cancer Lett , 102 : 199 – 204 .
  • Schulte , HR . 1987 . Biochemical Events in Nitrosamine‐induced Hepatocar‐cinogenesis: Relevance of Animal Data to Human Carcinogenesis , 17 – 19 . Lyon, , France : Int Agency Res Cancer . (IARC Sci Publ 84)
  • Ohshima , H and Bartsch , H . 1981 . “Quantitative estimation of endogenous nitrosation in humans by monitoring N‐nitrosoproline excreted in the urine” . Cancer Res , 41 : 3658 – 3662 .
  • Williams , DH . 1983 . “S‐nitrosation and the reactions of S‐nitroso compounds” . Chem Soc Rev , 15 : 171 – 196 .
  • Shenoy , NR and Choughuley , ASU . 1992 . “Inhibitory effect of diet related sulphydryl compounds on the formation of carcinogenic nitrosamines” . Cancer Lett , 65 : 227 – 232 .
  • Amagase , H and Milner , JA . 1993 . “Impact of various sources of garlic and their constituents on 7,12‐dimethylbenz[a]anthracene binding to mammary cell DNA” . Carcinogenesis , 14 : 1627 – 1631 .
  • Lin , XY , Liu , JZ and Milner , JA . 1994 . “Dietary garlic suppresses DNA adducts caused by N‐nitroso compounds” . Carcinogenesis , 15 : 349 – 352 .
  • Hong , YJ , Smith , T , Lee , MJ , Li , WS Ma , BL . 1991 . “Metabolism of carcinogenic nitrosamines by rat nasal mucosa and the effect of diallyl sulfide” . Cancer Res , 51 : 1509 – 1514 .
  • Brady , JF , Ishizaki , H , Fukuto , JM , Lin , MC Fadel , A . 1991 . “Inhibition of cytochrome P‐450 2E1 by diallyl sulfide and its metabolites” . Chem Res Toxicol , 4 : 642 – 647 .
  • Brady , JF , Wang , MH , Hong , JY , Xiao , F Li , Y . 1991 . “Modulation of rat hepatic microsomal monooxygenase enzymes and cytotoxicity by diallyl sulfide” . Toxicol Appl Pharmcol , 108 : 342 – 354 .
  • Rumruen , K and Pool , BL . 1984 . “Metabolic activation capabilities of S9 and hepatocytes from uninduced rats to convert carcinogenic N‐ni‐trosamines to mutagens” . Mutat Res , 140 : 147 – 153 .
  • Andrews , AW and Lijinski , W . 1980 . “The mutagenicity of 45 nitrosamines in Salmonella typhimurium” . Teratog Carcinog Mutagen , 1 : 295 – 303 .
  • Tadi , PP , Teel , RW and Lau , BH . 1991 . “Organosulfur compounds of garlic modulate mutagenesis, metabolism, and DNA binding of aflatoxin B1” . Nutr Cancer , 15 : 87 – 95 .
  • Mohammed , SV and Issenberg , P . 1986 . “Effects of phenol and 2,6‐di‐methoxyphenol (Syringol) on the in vivo formation of N‐nitrosomor‐pholine in rats” . Carcinogenesis , 7 : 867 – 870 .
  • Mirvish , S , Salmasi , S , Cohen , SM , Patil , K and Mahboubi , E . 1983 . “Liver and forestomach tumors and other forestomach lesions in rats treated with morpholine and sodium nitrite, with and without sodium ascor‐bate” . JNCI , 71 : 81 – 85 .
  • Fan , TY and Tannenbaum , SR . 1973 . “Factors influencing the rate of formation of nitrosomorpholine from morpholine and nitrite: acceleration by thiocyanate and other anions” . J Agric Food Chem , 21 : 237 – 240 .
  • Teel , RW and Castonguay , A . 1992 . “Antimutagenic effects of polyphenolic compounds” . Cancer Lett , 66 : 107 – 113 .
  • Yahagi , T , Nagao , M , Seino , Y , Matsushima , T Sugimura , T . 1977 . “Mutagenicities of N‐nitrosamines on Salmonella” . Mutat Res , 48 : 121 – 130 .
  • Mei , X , Lin , X , Liu , JZ , Lin , XY Song , PJ . 1989 . “The blocking effect of garlic on the formation of N‐nitrosoproline in humans” . Acta Nutr Sin , 11 : 141 – 146 .
  • Weinberg , DS , Manier , ML , Richardson , MD and Haibach , FG . 1993 . “Identification and quantification of organosulfur compliance markers in a garlic extract” . J Agric Food Chem , 41 : 37 – 41 .
  • Upchurch , GR Jr , Welch , GN and Loscalzo , J . 1995 . “S‐nitrosothiols: chemistry, biochemistry, and biological actions” . Adv Pharmacol , 34 : 343 – 349 .
  • Montesano , R and Magee , PN . 1994 . “Comparative metabolism in vitro of nitrosamines in various animal species including man” . In Chemical Carcinogenesis Essays , Edited by: Montesano , R and Tomatis , L . 39 Lyon, , France : Int Agency Res Cancer . (IARC Sci Publ 10)
  • Araki , A , Muramatsu , M and Matsushima , T . 1984 . “Comparison of mutagenicities of N‐nitrosamines on Salmonella typhimurium TA 100 and Escherichia coli WP2 UVRA/PKM101 using rat and hamster liver S‐9” . Gann , 75 : 8 – 16 .
  • Gomez , RF , Johnston , M and Sinskey , AJ . 1974 . “Activation of nitroso‐morpholine and nitrosopyrrolidine to bacterial mutagens” . Mutat Res , 24 : 5 – 7 .
  • Glatt , H and Oesch , F . 1985 . “Mutagenicity of cysteine and penicillamine and its enantiomeric selectivity” . Biochem Pharmacol , 34 : 3725 – 3728 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.