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Effect of acute acipimox administration on the rates of lipid and glycogen synthesis in cachectic tumor‐bearing rats

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Pages 100-106 | Received 01 Nov 1996, Accepted 21 Mar 1997, Published online: 04 Aug 2009

References

  • Obeid , OA and Emery , PW . 1993 . “Lipid metabolism in cachectic tumor‐bearing rats at different stages of tumor growth” . Nutr Cancer , 19 : 87 – 98 .
  • Emery , PW , Carpenter , TTA and Obeid , OA . 1993 . “Alterations in postprandial glycogen and lipid synthesis in cachectic tumor‐bearing rats” . Nutr Cancer , 20 : 231 – 240 .
  • Fanelli , C , Calderone , S , Epifano , L , De Vincenzo , A Modarelli , F . 1993 . “Demonstration of a critical role for free fatty acids in mediating counterregulatory stimulation of gluconeogenesis and suppression of glucose utilization in humans” . J Clin Invest , 92 : 1617 – 1622 .
  • Fuccella , LM , Goldaniga , G , Lovisolo , P , Maggi , E Musatti , L . 1980 . “Inhibition of lipolysis by nicotinic acid and by acipimox” . Clin Pharmacol Ther , 28 : 790 – 795 .
  • Fulcher , GR , Walker , M , Catalano , C , Agius , L and Alberti , KGMM . 1992 . “Metabolic effects of suppression of nonesterified fatty acid levels with acipimox in obese NIDDM subjects” . Diabetes , 41 : 1400 – 1408 .
  • Obeid , OA , Bell , JD and Emery , PW . 1996 . “The effect of acute acipimox administration on the contribution of different pathways to postprandial glycogen synthesis in cachectic tumour‐bearing rats” (abstr) . Proc Nutr Soc , 56 : 170A
  • Bernhart , F and Tomarelli , R . 1966 . “A salt mixture supplying the National Research Council estimates of the mineral requirement of the rat” . J Nutr , 89 : 495 – 500 .
  • Naismith , DJ , Akinyanju , P and Yudkin , J . 1969 . “Influence of caffeine containing beverages on the growth, food utilisation and plasma lipid of the rat” . J Nutr , 97 : 375 – 381 .
  • Cooke , BA , Lindh , LM , Janszen , FHA , van Driel , MJA Bakker , CP . 1979 . “A Leydig cell tumour, a model for the study of lutropin” . Biochim Biophys Acta , 583 : 320 – 331 .
  • Levine , JA and Emery , PW . 1987 . “The significance of learned food aversions in the aetiology of anorexia associated with cancer” . Br J Cancer , 56 : 73 – 78 .
  • Obeid , OA and Emery , PW . 1992 . “Changes in feeding behaviour in cachectic tumour bearing rats during the period of tumour growth” (abstr) . Proc Nutr Soc , 51 : 122A
  • Wolfe , RR . 1984 . Tracers in Metabolic Research: Radioisotope and Stable Isotope/Mass Spectrometry Methods , vol 9 , New York : Liss .
  • Morris , DL . 1948 . “Quantitative determination of carbohydrate with Drey‐wood's anthrone reagent” . Science , 107 : 245 – 255 .
  • Wehmeyer , N , Gunderson , H , Nauman , J , Savage , S and Hartzell , C . 1994 . “Determination of glycogen synthesis pathway by 13C nuclear magnetic resonance analysis” . Metabolism , 43 : 38 – 43 .
  • Kuwajima , M , Golden , S , Katz , J , Unger , RH Foster , D . 1986 . “Active hepatic glycogen synthesis from gluconeogenesis precursors despite high tissue levels of fructose 2,6‐biphosphate” . J Biol Chem , 261 : 2632 – 2637 .
  • Vaag , A , Skott , P , Damsbo , P , Gall , M‐A Richter , EA . 1991 . “Effect of the antilipolytic nicotinic acid analogue acipimox on whole body and skeletal muscle glucose metabolism in patients with non‐insulin‐dependent diabetes mellitus” . J Clin Invest , 88 : 1282 – 1290 .
  • Matthews , DC , Obeid , OA and Emery , PW . 1991 . “The effect of inhibiting gluconeogenesis on the synthesis of glycogen and lipid in cachectic tumour bearing rats” (abstr) . Proc Nutr Soc , 50 : 140A
  • Tayek , JA , Sutter , L , Manglik , S , Lillington , LB Grosvenor , M . 1995 . “Altered metabolism and mortality in patients with colon cancer receiving chemotherapy” . Am J Med Sci , 310 : 48 – 55 .
  • Legaspi , A , Jeevanandam , M , Starnes , HF and Brennan , MF . 1987 . “Whole body lipid and energy metabolism in the cancer patient” . Metabolism , 36 : 958 – 963 .
  • Spiegel , RJ , Schaefer , EJ , Magrath , IT and Edwards , BK . 1982 . “Plasma lipid alterations in leukemia and lymphoma” . Am J Med , 72 : 775 – 782 .
  • Dilman , VM , Berstein , LM , Ostroumova , MN , Tsyrlina , YV and Golubev , AG . 1981 . “Peculiarities of hyperlipidaemia in tumour patients” . Br J Cancer , 43 : 637 – 643 .
  • Semb , H , Peterson , J , Tavernier , J and Olivecrona , T . 1987 . “Multiple effects of tumor necrosis factor on lipoprotein lipase in vivo” . J Biol Chem , 262 : 8390 – 8394 .
  • Gold , J . 1975 . “Use of hydrazine sulfate in terminal and preterminal cancer patients: Results of investigational new drug (IND) study in 84 evaluable patients” . Oncology , 32 : 1 – 10 .
  • Gold , J . 1976 . “Hydrazine sulfate in the treatment of cancer” . Cancer Treat Rep , 60 : 964 – 965 .
  • Chlebowski , RT , Heber , D , Richardson , B and Block , JB . 1984 . “Influence of hydrazine sulfate on abnormal carbohydrate metabolism in cancer patients with weight loss” . Cancer Res , 44 : 857 – 861 .
  • Chlebowski , RT , Bulcavage , L , Grosvenor , M , Tsunokai , R Block , JB . 1987 . “Hydrazine sulfate in cancer patients with weight loss: a placebo‐controlled clinical experience” . Cancer , 59 : 406 – 410 .
  • Chlebowski , RT , Bulcavage , L , Grosvenor , M , Oktay , E Block , JB . 1990 . “Hydrazine sulfate influence on nutritional status and survival in non‐small cell lung cancer” . J Clin Oncol , 8 : 9 – 15 .
  • Filov , VA , Gershanovich , ML , Danova , LA and Ivin , BA . 1995 . “Experience of the treatment with Sehydrin (hydrazine sulfate, HS) in the advanced cancer patient” . Invest New Drugs , 13 : 89 – 97 .

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