Modulation of antioxidant enzymes in bleomycin‐treated rats by vitamin c and β‐carotene

References

• Buettner , GR and Moseley , PL . 1992 . “Ascorbate both activates and inactivates bleomycin by free radical generation” . Biochemistry , 31 : 9784 – 9788 .
   PubMedGoogle Scholar
• An , J and Hsie , AW . 1993 . “Polymerase chain reaction‐based deletion screening of bleomycin induced 6‐thioguanine‐resistant mutants in Chinese hamster ovary cells: the effects of an inhibitor and a mimic of Superoxide dismutase” . Mutat Res , 289 : 215 – 222 .
   PubMedGoogle Scholar
• Lyn‐Cook , LE , Aidoo , A , Lee , ME , Warner , W and Casciano , DA . 1995 . “Vitamin C intake influences cell proliferation and mutagenicity induced by benzo(α)pyrene (BP) and bleomycin (BM) in the rat” (abstr) . Environ Mol Mutat , 25 : 32
   Google Scholar
• Huang , CH , Mirabelli , CK , Mong , S and Crooke , ST . 1983 . “Effects of DNA superhelical changes induced by ethidium bromide on the DNA‐degrading activity of two antitumor antibiotics, bleomycin and phleomycin” . Cancer Res , 43 : 2849 – 2856 .
   PubMedGoogle Scholar
• Vig , BK and Lewis , R . 1978 . “Genetic toxicology of bleomycin” . Mutat Res , 160 : 121 – 131 .
   Google Scholar
• Povirk , LF and Austin , MJF . 1991 . “Genotoxicity of bleomycin” . Mutat Res , 257 : 127 – 143 .
   PubMed Web of Science ®Google Scholar
• Cederberg , H and Ramel , C . 1989 . “Modifications of the effects of bleomycin in the somatic mutation and recombination test in Drosophila melanogaster” . Mutat Res , 214 : 69 – 80 .
   PubMedGoogle Scholar
• Cunningham , ML , Ringrose , PS and Lokesh , BR . 1984 . “Inhibition of the genotoxicity of bleomycin by Superoxide dismutase” . Mutat Res , 135 : 199 – 202 .
   PubMedGoogle Scholar
• Sausville , EA , Peisach , J and Horwitz , SB . 1978 . “Effect of chelating agents and metal ions on the degradation of DNA by bleomycin” . Biochemistry , 17 : 2746 – 2754 .
   PubMed Web of Science ®Google Scholar
• Floyd , RA and Carney , JM . 1993 . “The role of metal ions in oxidative processes and aging” . Toxicol Ind Health , 9 : 197 – 214 .
   PubMedGoogle Scholar
• Byung Pal , YU . 1994 . “Cellular defenses against damage from reactive oxygen species” . Physiol Rev , 14 : 139 – 162 .
   Google Scholar
• Machlin , LJ and Bendich , A . 1987 . “Free radical tissue damage: protective role of antioxidant nutrients” . FASEB J , 1 : 441 – 445 .
   PubMed Web of Science ®Google Scholar
• Bendich , A , Machlin , LJ , Scandurra , O , Burton , GW and Wayner , DM . 1986 . “The antioxidant role of vitamin C” . Adv Free Radical Biol Med , 2 : 419 – 444 .
   Web of Science ®Google Scholar
• Frei , B , Stocker , R and Ames , BN . 1988 . “Antioxidant defenses and lipid peroxidation in human blood plasma” . Proc Natl Acad Sci USA , 85 : 9748 – 9752 .
   PubMed Web of Science ®Google Scholar
• Frei , B , England , L and Ames , BN . 1989 . “Ascorbate is an outstanding antioxidant in human blood plasma” . Proc Natl Acad Sci USA , 86 : 6377 – 6781 .
   PubMed Web of Science ®Google Scholar
• Wattenberg , LW . 1978 . “Inhibition of chemical carcinogenesis” . JNCI , 6 : 11 – 18 .
   Google Scholar
• Henson , DE , Block , G and Levine , M . 1991 . “Ascorbic acid: biologie functions and relation to cancer” . JNCI , 83 : 547 – 550 .
   PubMed Web of Science ®Google Scholar
• Shamberger , RI , Corlett , CL , Beaman , KD and Kasten , BL . 1979 . “Anti‐oxidants reduce the mutagenic effect of malonaldehyde and β‐propio‐lactone” . Mutat Res , 66 : 349 – 355 .
   PubMedGoogle Scholar
• Raina , V and Gurtoo , HL . 1985 . “Effects of vitamins A, C, and E on afla‐toxin B1‐induced mutagenesis In Salmonella typhimurium TA‐98 and TA‐100” . Teratogenesis Carcinogen Mutagen , 5 : 29 – 40 .
   PubMedGoogle Scholar
• Aidoo , A , Lyn‐Cook , LE , Lensing , S and Warner , W . 1994 . “Ascorbic acid (vitamin C) modulates the mutagenic effects produced by an alkylating agent in vivo” . Environ Mol Mutagen , 24 : 220 – 228 .
   PubMedGoogle Scholar
• Burton , GW . 1989 . “Antioxidant actions of carotenoids” . J Nutr , 119 : 109 – 111 .
   PubMed Web of Science ®Google Scholar
• Basu , TK , Temple , NJ and Ng , I . 1987 . “Effect of dietary β‐carotene on hepatic drug‐metabolizing enzymes in mice” . J Clin Biochem Nutr , 3 : 95 – 102 .
   Google Scholar
• Van Lieshout , EMM , Peters , WHM and Jansen , JBMJ . 1996 . “Effect of oltipraz, β‐tocopherol, β‐carotene and phenethylisothiocyanate on rat oesophageal, gastric, colonie and hepatic glutathione, glutathione S‐transferase and peroxidase” . Carcinogenesis , 17 : 1439 – 1445 .
   PubMed Web of Science ®Google Scholar
• Mathews‐Roth , MM . 1982 . “Antitumor activity of β‐carotene, canthaxanthin and phytoene” . Oncology , 39 : 33 – 37 .
   PubMed Web of Science ®Google Scholar
• Lambert , LA , Koch , WH , Warner , WG and Kornhauser , A . 1990 . “Antitumor activity in skin of Skh and Sencar mice by two dietary β‐carotene formulations” . Nutr Cancer , 13 : 213 – 221 .
   PubMed Web of Science ®Google Scholar
• US Department of Health and Human Services . 1986 . Guide for the Care and Use of Laboratory Animals , (DHHS‐NIH Publ 8) Washington DC : Dept of Health and Human Services .
   Google Scholar
• Ji , LL , Dillon , D and Wu , E . 1990 . “Alteration of antioxidant enzymes with aging in rat skeletal muscle and liver” . Am J Physiol , 258 : R918 – R923 .
   PubMed Web of Science ®Google Scholar
• Wheeler , CR , Salzman , JA , Elsayed , NM , Omaye , ST and Korte , DW Jr . 1990 . “Automated assays for Superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase activity” . Anal Biochem , 184 : 193 – 199 .
   PubMed Web of Science ®Google Scholar
• Bergmeyer , HU . 1974 . “Glucose 6‐phosphate dehydrogenase from yeast” . In Methods in Enzymatic Analysis, , 2nd ed , Edited by: Bergmeyer , HU . vol 1 , 458 – 459 . New York : Academic .
   Google Scholar
• Sikic , BI . 1986 . “Biochemical and cellular determinants of bleomycin tox‐icity” . Cancer Surv , 5 : 81 – 91 .
   PubMedGoogle Scholar
• Padbury , G , Sugar , SG , Labeque , R and Marnett , LJ . 1988 . “Ferric bleomycin catalyzed reduction of 10‐hydroperoxy‐8, 12‐octadecadienoic acid: evidence for homolytic O‐O bond scission” . Biochemistry , 27 : 7846 – 7852 .
   PubMedGoogle Scholar
• Umezawa , HT , Takeuchi , S , Hori , I , Sawa , T and Ishizuka , M . 1972 . “Studies on the mechanism of antitumor effect of bleomycin on squamous carcinoma” . J Antibiot , 25 : 409 – 420 .
   PubMed Web of Science ®Google Scholar
• Akiyama , SI , Ikezaki , K , Kuramochi , H , Takahashi , K and Kuwawno , M . 1981 . “Bleomycin resistant cells contain increased bleomycin hydrolase activities” . Biochem Biophys Res Commun , 101 : 55 – 60 .
   PubMedGoogle Scholar
• Puget , K and Michelson , AM . 1974 . “Iron containing Superoxide dismutases from luminous bacteria” . Biochimie , 56 : 1255 – 1267 .
   PubMed Web of Science ®Google Scholar
• Winterbourn , CC . 1979 . "Comparison of Superoxide with other reducing agents in the biological production of hydroxyl radicals” . Biochem J , 182 : 625 – 628 .
   PubMed Web of Science ®Google Scholar
• Kaur , H and Halliwell , B . 1994 . “Detection of hydroxyl radicals by aromatic hydroxylation” . Methods Enzymol , 233 : 67 – 82 .
   PubMed Web of Science ®Google Scholar
• Feuers , RJ , Weindruch , R and Hart , RW . 1993 . “Caloric restriction, aging and antioxidant enzymes” . Mutat Res , 295 : 191 – 200 .
   PubMedGoogle Scholar
• Astorg , P , Gradelet , S , Leclerc , J , Canivenc , MC and Siess , MH . 1994 . “Effects of β‐carotene and canthaxanthin on liver xenobiotic‐metabo‐lizing enzymes in rat” . Food Chem Toxicol , 32 : 735 – 742 .
   PubMed Web of Science ®Google Scholar
• Stadtman , ER . 1992 . “Protein oxidation and aging” . Science , 257 : 1220 – 1224 .
   PubMed Web of Science ®Google Scholar