Genistein‐induced G2‐m arrest, P21^WAF1 upregulation, and apoptosis in a non‐small‐cell lung cancer cell line

References

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• Kyle , E , Neckers , L , Takimoto , C , Curt , G and Gergan , R . 1997 . Genistein‐induced apoptosis of prostate cancer cells is preceded by a specific decrease in focal adhesion kinase activity . Mol Pharmacol , 51 : 193 – 200 .
   PubMed Web of Science ®Google Scholar
• Barlogie , B , Barber , MN and Schumann , J . 1983 . Flow cytometry in clinical cancer research . Cancer Res , 43 : 3977 – 3982 .
   Web of Science ®Google Scholar
• Philpott , NJ , Turner , AJ , Scopes , J , Westby , M Marsh , JC . 1996 . The use of 7‐amino actinomycin D in identifying apoptosis: simplicity of use and broad spectrum of application compared with other techniques . Blood , 87 : 2244 – 2251 .
   PubMed Web of Science ®Google Scholar
• Tchou , WW , Rom , WN , Chou , T and Wong , KM . 1996 . Novel form of p21 protein in phorbol ester‐induced G2‐M arrest . J Biol Chem , 271 : 29556 – 29560 .
   PubMed Web of Science ®Google Scholar
• Hunakova , L , Sedlak , J , Klobusicka , M , Duraj , J and Chorvath , B . 1994 . Tyrosine kinase inhibitor‐induced differentiation of K‐562 cells: alterations of cell cycle and cell surface phenotype . Cancer Lett , 81 : 81 – 87 .
   PubMed Web of Science ®Google Scholar
• Jacquet , P , Saint , L , Barrio , S and Baugnet , ML . 1995 . Morphological effects of caffeine, okadaic acid and genistein in one‐cell mouse embryos blocked in G2 by X‐irradiation . Int J Radial Biol , 67 : 347 – 358 .
   PubMed Web of Science ®Google Scholar
• Roberts , JM , Koff , A , Polyak , K , Firpo , E Collins , S . 1994 . Cyclins, cdks, and cyclin kinase inhibitors . Cold Spring Harbor Symp Quant Biol , 59 : 31 – 38 .
   PubMedGoogle Scholar
• Sherr , CJ . 1994 . Cancer cell cycles . Science , 274 : 1672 – 1677 .
   Web of Science ®Google Scholar
• Earnshaw , WC and Heck , M . 1985 . Localization of topoisomerase II in mitotic chromosomes . J Cell Biol , 100 : 1706 – 1715 .
   PubMed Web of Science ®Google Scholar
• Heck , M and Earnshaw , WC . 1986 . Topoisomerase II: a specific marker for cell proliferation . J Cell Biol , 103 : 2569 – 2581 .
   PubMed Web of Science ®Google Scholar
• Estey , EH , Silberman , L , Benin , M , Andersson , BS and Zwelling , LA . 1987 . The interaction between nuclear topoisomerase II activity from human leukemia cells, exogenous DNA, and 4'‐(9‐acridinylami‐no)methanesulfon‐m‐anisidide (m‐AMSA) or 4‐(4,6‐O‐ethylidene‐β‐d‐glucopyranoside) (VP‐16) indicates the sensitivity of the cells to the drugs . Biochem Biophys Res Commun , 144 : 787 – 793 .
   PubMed Web of Science ®Google Scholar
• Barlogie , B and Drewinko , B . 1978 . Cell cycle stage‐dependent induction of G2 phase arrest by different antitumor agents . Eur J Cancer , 14 : 741 – 745 .
   PubMed Web of Science ®Google Scholar
• Misra , NC and Roberts , D . 1975 . Inhibition by 4'‐demethyl‐epodophyllo‐toxin 9‐(4,6‐O‐2‐ethylidene‐β‐d‐glucopyranoside) of human lympho‐blast cultures in G2 phase of the cell cycle . Cancer Res , 35 : 99 – 105 .
   PubMed Web of Science ®Google Scholar
• Sherr , CJ . 1994 . G, phase progression: cycling on cue . Cell , 79 : 551 – 555 .
   PubMed Web of Science ®Google Scholar
• Xiong , Y , Hannon , GJ , Zhang , H , Casso , D Kobayashi , R . 1993 . p21 is a universal inhibitor of cyclin kinases . Nature , 366 : 701 – 704 .
   PubMed Web of Science ®Google Scholar
• Kerr , JF , Winterford , CM and Harmon , BV . 1993 . Apoptosis: its significance in cancer and cancer therapy . Cancer , 73 : 2013 – 2026 .
   Web of Science ®Google Scholar
• Markovitz , J , Linassier , C , Fossi , P , Couprie , J Pierre , J . 1989 . Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II . Cancer Res , 119 : 5111 – 5117 .
   Google Scholar
• Yamashita , Y , Kawada , S and Nakano , H . 1990 . Induction of mammalian topoisomerase II‐dependent DNA cleavage by nonintercalative flavonoids, genistein and phorobol . Biochem Pharmacol , 39 : 737 – 744 .
   PubMed Web of Science ®Google Scholar
• Adlercreutz , H , Markkanen , H and Watanabe , S . 1993 . Plasma concentrations of phyto‐oestrogens in Japanese men . Lancet , 342 : 1209 – 1210 .
   PubMed Web of Science ®Google Scholar
• Barnes , S . 1995 . Effects of genistein on in vivo models of cancer . J Nutr , 125 : 777s – 783s .
   PubMed Web of Science ®Google Scholar