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Neuro-Ophthalmology Volume 41, 2017 - Issue 1
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Case Reports

Anti-Collapsing Response-Mediating Protein-5 Antibody–Positive Paraneoplastic Perioptic Neuritis without Typical Neurological Symptoms

Nozomi IgarashiDepartment of Ophthalmology, Graduate School of Medicine, The University of Tokyo, Tokyo, JapanCorrespondence[email protected]
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,
Hiromasa SawamuraDepartment of Ophthalmology, Graduate School of Medicine, The University of Tokyo, Tokyo, JapanView further author information
,
Toshikatsu KaburakiDepartment of Ophthalmology, Graduate School of Medicine, The University of Tokyo, Tokyo, JapanView further author information
&
Makoto AiharaDepartment of Ophthalmology, Graduate School of Medicine, The University of Tokyo, Tokyo, JapanView further author information
Pages 24-29 | Received 04 Aug 2016, Accepted 22 Sep 2016, Published online: 27 Oct 2016

References

  • Gordon LK. Paraneoplastic syndromes in neuro-ophthalmology. J Neuroophthalmol 2015;35:306–314.
  • Chan JW. Paraneoplastic retinopathies and optic neuropathies. Surv Ophthalmol 2003;48:12–38.
  • Calvert PC. A CR(I)MP in the optic nerve: recognition and implications of paraneoplastic optic neuropathy. J Neuroophthalmol 2006;26:165–167.
  • Thambisetty MR, Scherzer CR, Yu Z, Lennon VA, Newman NJ. Paraneoplastic optic neuropathy and cerebellar ataxia with small cell carcinoma of the lung. J Neuroophthalmol 2001;21:164–167.
  • Cross SA, Salomao DR, Parisi JE, Kryzer TJ, Bradley EA, Mines JA, Lam BL, Lennon VA. Paraneoplastic autoimmune optic neuritis with retinitis defined by CRMP-5-IgG. Ann Neurol 2003;54:38–50.
  • Rahimy E, Sarraf D. Paraneoplastic and non-paraneoplastic retinopathy and optic neuropathy: evaluation and management. Surv Ophthalmol 2013;58:430–458.
  • Sheorajpanday R, Slabbynck H, Van De Sompel W, Galdermans D, Neetens I, De Deyn PP. Small cell lung carcinoma presenting as collapsin response-mediating protein (CRMP)-5 paraneoplastic optic neuropathy. J Neuroophthalmol 2006;26:168–172.
  • Margolin E, Flint A, Trobe JD. High-titer collapsin response-mediating protein-associated (CRMP-5) paraneoplastic optic neuropathy and vitritis as the only clinical manifestations in a patient with small cell lung carcinoma. J Neuroophthalmol 2008;28:17–22.
  • Yu Z, Kryzer TJ, Griesmann GE, Kim K, Benarroch EE, Lennon VA. CRMP-5 neuronal autoantibody: marker of lung cancer and thymoma-related autoimmunity. Ann Neurol 2001;49:146–154.
  • Honnorat J, Antoine JC. Paraneoplastic neurological syndromes. Orphanet J Rare Dis 2007;2:22.
  • Adamus G, Brown L, Schiffman J, Iannaccone A. Diversity in autoimmunity against retinal, neuronal, and axonal antigens in acquired neuro-retinopathy. J Ophthalmic Inflamm Infect 2011;1:111–121.
  • Arés-Luque A, García-Tuñón LA, Saiz A, Cabezas BC, Hernández-Echebarría LE, Franco M, Toribio A, Tejada J, Graus F. Isolated paraneoplastic optic neuropathy associated with small-cell lung cancer and anti-CV2 antibodies. J Neurol 2007;254:1131–1132.
  • Honnorat J, Antoine JC, Derrington E, Aguera M, Belin MF. Antibodies to a subpopulation of glial cells and a 66 kD developmental protein in patients with paraneoplastic neurological syndromes. J Neurol Neurosurg Psychiatr 1996;61:270–278.
  • de la Sayette V, Bertran F, Honnorat J, Schaeffer S, Iglesias S, Defer G. Paraneoplastic cerebellar syndrome and optic neuritis with anti-CV2 antibodies: clinical response to excision of the primary tumor. Arch Neurol 1998;55:405–408.
  • Yu Z, Kryzer TJ, Griesmann GE, Kim K, Benarroch EE, Lennon VA. CRMP-5 neuronal autoantibody: marker of lung cancer and thymoma-related autoimmunity. Ann Neurol 2001;49:146–154.
  • Saito M, Saito W, Kanda A, Ohguro H, Ishida S. A case of paraneoplastic optic neuropathy and outer retinitis positive for autoantibodies against collapsin response mediator protein-5, recoverin, and α-enolase. BMC Ophthalmol 2014;14:article 5.
  • O’Keefe GA, Rao NA. Vogt-Koyanagi-Harada disease. Surv Ophthalmol 2016. doi:10.1016/j.survophthal.2016.05.002.
  • Pulido J, Cross SA, Lennon VA, Pulido J, Swanson D, Muench M, Lachance DH. Bilateral autoimmune optic neuritis and vitreitis related to CRMP-5-IgG: intravitreal triamcinolone acetonide therapy of four eyes. Eye (Lond) 2008;22:1191–1193.
  • Luiz JE, Lee AG, Keltner JL, Thirkill CE, Lai EC. Paraneoplastic optic neuropathy and autoantibody production in small-cell carcinoma of the lung. J Neuroophthalmol 1998;18:178–181.
  • Slamovits TL, Posner JB, Reidy DL, Thirkill CE, Keltner JL. Pancreatic neuroendocrine paraneoplastic optic neuropathy: confirmation with antibody to optic nerve and hepatic metastasis. J Neuroophthalmol 2013;33:21–25.

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