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Neuro-Ophthalmology Volume 43, 2019 - Issue 6
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Case Reports

Increased Microcirculation on Optic Nerve Head by Laser Speckle Flowgraphy at Early Stage of Leber Hereditary Optic Neuropathy

Toshiki WatanabeDepartment of Ophthalmology, Kyorin University, Tokyo, Japan;Watanabe Eye Clinic, Tokyo, JapanCorrespondence[email protected]
,
Yukihiko MashimaDepartment of Ophthalmology, Kyorin University, Tokyo, Japan
,
Kazuteru KigasawaDepartment of Ophthalmology, Kyorin University, Tokyo, Japan
,
Asako MashimaDepartment of Ophthalmology, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan
,
Masahiko ShimuraDepartment of Ophthalmology, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan
&
Akito HirakataDepartment of Ophthalmology, Kyorin University, Tokyo, Japan
Pages 411-416 | Received 18 Jun 2018, Accepted 18 Sep 2018, Published online: 11 Oct 2018

References

  • Newman NJ. The hereditary optic neuropathies. In: Miller NR, Newman NJ, eds. Walsh and Hoyt’s Clinical Neuro-Ophthalmology. Vol. 1. 5th ed. Baltimore: Williams and Wilkins; 1998:741–773.
  • Dimitriadis K, Leonhardt M, Yu-Wai-Man P, Kirkman MA, Korsten A, De Coo IF, Chinnery PF, Klopstock T. Leber’s hereditary optic neuropathy with late disease onset: clinical and molecular characteristics of 20 patients. Orphanet J Rare Dis. 2014;9:158. doi:10.1186/s13023-014-0158-9.
  • Giraudet S, Lamirel C, Amati-Bonneau P, Reynier P, Bonneau D, Milea D, Cochereau I. Never too old to harbour a young man’s disease? Br J Ophthalmol. 2011;95:887,896–897. doi:10.1136/bjo.2009.161539.
  • Shimada Y, Horiguchi M. Leber hereditary optic neuropathy associated with bilateral macular holes. Neuroophthalmology. 2016;40:125–129. doi:10.3109/01658107.2016.1148744.
  • Shah VA, Randhawa S, Mizen T, Lee AG, Foroozan R. You’re too old for that. Surv Ophthalmol. 2008;53:403–410. doi:10.1016/j.survophthal.2008.04.003.
  • Barboni P, Carbonelli M, Savini G, Ramos Cdo V, Carta A, Berezovsky A, Salomao SR, Carelli V, Sadun AA. Natural history of Leber’s hereditary optic neuropathy: longitudinal analysis of the retinal nerve fiber layer by optical coherence tomography. Ophthalmology. 2010;117:623–627. doi:10.1016/j.ophtha.2009.07.026.
  • Akiyama H, Kashima T, Li D, Shimoda Y, Mukai R, Kishi S. Retinal ganglion cell analysis in Leber’s hereditary optic neuropathy. Ophthalmology. 2013;120:1943–1944. doi:10.1016/j.ophtha.2013.05.031.
  • Tamaki Y, Araie M, Kawamoto E, Eguchi S, Fujii H. Noncontact, two-dimensional measurement of retinal microcirculation using laser speckle phenomenon. Invest Ophthalmol Vis Sci. 1994;35:3825–3834.
  • Konishi N, Tokimoto Y, Kohra K, Fujii H. New laser speckle flowgraphy system using CCD camera. Opt Rev. 2002;9:163–169. doi:10.1007/s10043-002-0163-4.
  • Aizawa N, Yokoyama Y, Chiba N, Omodaka K, Yasuda M, Otomo T, Nakamura M, Fuse N, Nakazawa T. Reproducibility of retinal circulation measurements obtained using laser speckle flowgraphy-NAVI in patients with glaucoma. Clin Ophthalmol. 2011;5:1171–1176. doi:10.2147/OPTH.S22093.
  • Shiga Y, Kunikata H, Aizawa N, Kiyota N, Maiya Y, Yokoyama Y, Omodaka K, Takahashi H, Yasui T, Kato K, Iwase A, Nakazawa T. Optic nerve head blood flow, as measured by Laser speckle flowgraphy, is significantly reduced in preperimetric glaucoma. Curr Eye Res. 2016;41:1447–1453. doi:10.3109/02713683.2015.1127974.
  • Inoue M, Himori N, Kunikata H, Takeshita T, Aizawa N, Shiga Y, Omodaka K, Nishiguchi KM, Takahashi H, Nakazawa T. The reduction of temporal optic nerve head microcirculation in autosomal dominant optic atrophy. Acta Ophthalmol. 2016;94:e580–e585. doi:10.1111/aos.12999.
  • Maekubo T, Chuman H, Naoi N. Laser speckle flowgraphy for differentiating between nonarteritic ischemic optic neuropathy and anterior optic neuritis. Jpn J Ophthalmol. 2013;57:385–390. doi:10.1007/s10384-013-0246-8.
  • Aizawa N, Kunikata H, Nitta F, Shiga Y, Omodaka K, Tsuda S, Nakazawa T. Age- and sex-dependency of laser speckle flowgraphy measurements of optic nerve vessel microcirculation. PLoS One. 2016;11:e0148812. doi:10.1371/journal.pone.0148812.
  • Gaier ED, Gittinger JW, Cestari DM, Miller JB. Peripapillary capillary dilation in Leber hereditary optic neuropathy revealed by optical coherence tomographic angiopathy. JAMA Ophthalmol. 2016;134:1332–1334. doi:10.1001/jamaophthalmol.2016.3593.
  • Balducci N, Cascavilla ML, Ciardella A, La Morgia C, Parisi V, Bandello F, Sadun AA, Carelli V, Barboni P. Peripapillary vessel density changes in Leber’s hereditary optic neuropathy: a new biomarker. Clin Exp Ophthalmol. May 22, 2018. Epub ahead of print. doi:10.1111/ceo.13326.

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