469
Views
2
CrossRef citations to date
0
Altmetric
Articles

Escitalopram and progressive muscle relaxation training are both effective for the treatment of hot flashes in patients with breast cancer: a randomized controlled trial

, , , , , , , & show all
Pages 393-399 | Received 08 May 2021, Accepted 22 Sep 2021, Published online: 14 Oct 2021

References

  • Ferlay J, Soerjomataram I, Ervik M, et al. Lyon, France: international agency for research on cancer. Cancer Incidence a Mortal Worldwide: IARC Cancer Base. 2012;11:2013.
  • Siegel RL, Miller KD, Jemal A. Cancer statistics, 2016. CA Cancer J Clin. 2016;66(1):7–30.
  • Clarke M, Collins R, Darby S, et al. Early breast cancer trialists collaborative group (EBCTCG). Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet. 2005;366(9503):2087–2106.
  • Darby S, McGale P, Correa C, et al. Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10 801 women in 17 randomised trials. Lancet. 2011;378(9804):1707–1716.
  • Jatoi I, Miller AB. Why is breast-cancer mortality declining? Lancet Oncol. 2003;4(4):251–254.
  • Knobf MT. The influence of endocrine effects of adjuvant therapy on quality of life outcomes in younger breast cancer survivors. The Oncologist. 2006;11(2):96–110.
  • Antoine C, Vandromme J, Fastrez M, et al. A survey among breast cancer survivors: treatment of the climacteric after breast cancer. Climacteric. 2008;11(4):322–328.
  • Biglia N, Cozzarella M, Cacciari F, et al. Menopause after breast cancer: a survey on breast cancer survivors. Maturitas. 2003;45(1):29–38.
  • Hickey M, Saunders C, Partridge A, et al. Practical clinical guidelines for assessing and managing menopausal symptoms after breast cancer. Ann Oncol. 2008;19(10):1669–1680.
  • Freedman RR. Hot flashes: behavioral treatments, mechanisms, and relation to sleep. Am J Med. 2005;118 Suppl 12B(12):124–130.
  • de Zambotti M, Colrain IM, Javitz HS, et al. Magnitude of the impact of hot flashes on sleep in perimenopausal women. Fertil Steril. 2014;102(6):1708–1715.
  • Erlik Y, Tataryn IV, Meldrum DR, et al. Association of waking episodes with menopausal hot flushes. JAMA. 1981;245(17):1741–1744.
  • MacLennan AH, Broadbent JL, Lester S, et al. Oral oestrogen and combined oestrogen/progestogen therapy versus placebo for hot flushes. Cochrane Database Syst Rev. 2004;4: CD002978.
  • Heiss G, Wallace R, Anderson GL, et al. Health risks and benefits 3 years after stopping randomized treatment with estrogen and progestin. JAMA. 2008;299(9):1036–1045.
  • Rossouw JE, Anderson GL, Prentice RL, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the women’s health initiative randomized controlled trial. JAMA. 2002;288(3):321–333.
  • Holmberg L, Iversen O-E, Rudenstam CM, et al. Increased risk of recurrence after hormone replacement therapy in breast cancer survivors. J Natl Cancer Inst. 2008;100(7):475–482.
  • Sismondi P, Kimmig R, Kubista E, et al. Effects of tibolone on climacteric symptoms and quality of life in breast cancer patients—data from LIBERATE trial. Maturitas. 2011;70(4):365–372.
  • ACOG practice bulletin no. 141: management of menopausal symptoms. Obstet Gynecol. 2014;123(1):202–216.
  • Sassarini J, Lumsden MA. 2013. Non-hormonal management of vasomotor symptoms. Taylor & Francis.
  • Barton DL, LaVasseur BI, Sloan JA, et al. Phase III, placebo-controlled trial of three doses of citalopram for the treatment of hot flashes: NCCTG trial N05C9. J Clin Oncol. 2010;28(20):3278–3283.
  • Dobkin RD, Menza M, Allen LA, et al. Escitalopram reduces hot flashes in non-depressed menopausal women: a pilot study. Ann Clin Psychiatry. 2009;21(2):70.
  • Freeman MP, Hirschberg AM, Wang B, et al. Duloxetine for major depressive disorder and daytime and nighttime hot flashes associated with the menopausal transition. Maturitas. 2013;75(2):170–174.
  • Loprinzi CL, Kugler JW, Sloan JA, et al. Venlafaxine in management of hot flashes in survivors of breast cancer: a randomised controlled trial. Lancet. 2000;356(9247):2059–2063.
  • Simon JA, Portman DJ, Kaunitz AM, et al. Low-dose paroxetine 7.5 mg for menopausal vasomotor symptoms: two randomized controlled trials. Menopause. 2013;20(10):1027–1035.
  • Shams T, Firwana B, Habib F, et al. SSRIs for hot flashes: a systematic review and meta-analysis of randomized trials. J Gen Intern Med. 2014;29(1):204–213.
  • Biglia N, Bounous VE, Susini T, et al. Duloxetine and escitalopram for hot flushes: efficacy and compliance in breast cancer survivors. Eur J Cancer Care. 2018;27(1):e12484.
  • Fugate SE, Church CO. Nonestrogen treatment modalities for vasomotor symptoms associated with menopause. Ann Pharmacother. 2004;38(9):1482–1499.
  • Boekhout AH, Vincent AD, Dalesio OB, et al. Management of hot flashes in patients who have breast cancer with venlafaxine and clonidine: a randomized, double-blind, placebo-controlled trial. J Clin Oncol. 2011;29(29):3862–3868.
  • Kent JM. SNaRIs, NaSSAs, and NaRIs: new agents for the treatment of depression. Lancet. 2000;355(9207):911–918.
  • Aguglia E, Ravasio R, Simonetti M, et al. Use and treatment modalities for SSRI and SNRI antidepressants in Italy during the period 2003–2009. Curr Med Res Opin. 2012;28(9):1475–1484.
  • North American Menopause Society. Non-hormonal management of menopause-associated vasomotor symptoms: 2015 position statement of the North American Menopause Society. Menopause. 2015;22(11):1155–1172.
  • Szabo RA, Marino JL, Hickey M. Managing menopausal symptoms after cancer. Climacteric. 2019;22(6):572–578.
  • Molassiotis A, Yung HP, Yam BM, et al. The effectiveness of progressive muscle relaxation training in managing chemotherapy-induced nausea and vomiting in Chinese breast cancer patients: a randomised controlled trial. Support Care Cancer. 2002;10(3):237–246.
  • Shell GA, Kirsch S. Psychosocial issues, outcomes and quality of life. Oncol Nurs. 2001;4:948–970.
  • Wright S, Courtney U, Crowther D. A quantitative and qualitative pilot study of the perceived benefits of autogenic training for a group of people with cancer. Eur J Cancer Care. 2002;11(2):122–130.
  • Hunter M. Cognitive behavioural interventions for premenstrual and menopausal symptoms. J Reprod Infant Psychol. 2003;21(3):183–193.
  • Hunter MS, Liao KL. Evaluation of a four‐session cognitive–behavioural intervention for menopausal hot flushes. Br J Health Psychol. 1996;1(2):113–125.
  • Lindh-Åstrand L, Nedstrand E, Wyon Y, et al. Vasomotor symptoms and quality of life in previously sedentary postmenopausal women randomised to physical activity or estrogen therapy. Maturitas. 2004;48(2):97–105.
  • McCallie MS, Blum CM, Hood CJ. Progressive muscle relaxation. J Human Behav Soc Environ. 2006;13(3):51–66.
  • Park S, Song C, Oh Y-A, et al. Comparison of physiological and psychological relaxation using measurements of heart rate variability, prefrontal cortex activity, and subjective indexes after completing tasks with and without foliage plants. Int J Environ Res Public Health. 2017;14(9):1087.
  • Jacobson E. Progressive muscle relaxation. J Abnorm Psychol. 1938;75(1):18.
  • Heinemann LAJ, Potthoff P, Schneider HPG. International versions of the menopause rating scale (MRS). Health Qual Life Outcomes. 2003;1(1):28.
  • Nazarpour S, Simbar M, Ramezani Tehrani F. Effects of the severity of menopausal symptoms on sexual function in postmenopausal women TT – تأثیر شدت نشانه‌های یائسگی بر عملکرد جنسی زنان یائسه. JQUMS. 2015;19(4):54–63.
  • Faul F, Erdfelder E, Buchner A, et al. Statistical power analyses using G* power 3.1: tests for correlation and regression analyses. Behavior Res Methods. 2009;41(4):1149–1160.
  • Grady D. Clinical practice. Management of menopausal symptoms. N Engl J Med. 2006;355(22):2338–2347.
  • North American Menopause Society. The 2012 hormone therapy position statement of the North American Menopause Society. Menopause. 2012;19(3):257.
  • Reed SD, Ludman EJ, Newton KM, et al. Depressive symptoms and menopausal burden in the midlife. Maturitas. 2009;62(3):306–310.
  • Fann JR, Thomas-Rich AM, Katon WJ, et al. Major depression after breast cancer: a review of epidemiology and treatment. Gen Hosp Psychiatry. 2008;30(2):112–126.
  • Lueboonthavatchai P. Prevalence and psychosocial factors of anxiety and depression in breast cancer patients. J-Med Assoc Thailand. 2007;90(10):2164.
  • Freeman EW, Guthrie KA, Caan B, et al. Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial. JAMA. 2011;305(3):267–274.
  • Soares CN, Arsenio H, Joffe H, et al. Escitalopram versus ethinyl estradiol and norethindrone acetate for symptomatic peri-and postmenopausal women: impact on depression, vasomotor symptoms, sleep, and quality of life. Menopause. 2006;13(5):780–786.
  • Fenlon DR, Corner JL, Haviland JS. A randomized controlled trial of relaxation training to reduce hot flashes in women with primary breast cancer. J Pain Symptom Manage. 2008;35(4):397–405.
  • Irvin JH, Domar AD, Clark C, et al. The effects of relaxation response training on menopausal symptoms. J Psychosom Obstetr Gynec. 1996;17(4):202–207.
  • Demiralp M, Oflaz F, Komurcu S. Effects of relaxation training on sleep quality and fatigue in patients with breast cancer undergoing adjuvant chemotherapy. J Clin Nurs. 2010;19(7-8):1073–1083.
  • Cohen M, Fried G. Comparing relaxation training and cognitive-behavioral group therapy for women with breast cancer. Research on Social Work Practice. 2007;17(3):313–323.
  • Cascade E, Kalali AH, Kennedy SH. Real-world data on SSRI antidepressant side effects. Psychiatry. 2009;6(2):16–18.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.