- McEvoy CE, Niewoehner DE: Adverse effects of corticosteroid therapy for COPD. A critical review. Chest 1997;lll:732-743.
- Hanania NA, Chapman KR, Resten S: Adverse effects of inhaled corticosteroids. Am J Med. 1995;98:196-208.
- Wanner A, Salathe M, O'Riordan TG: Mucociliary clearance in the airways. Am J Respir Crit Care Med. 1996;154:1868-1902.
- Kim KC, McCracken K, Lee BC, Shin CY.Jo MJ, Lee CJ, Ko KH: Airway goblet cell mucin: its structure and regulation of secretion. Eur Resp J. 1997;10:2644-2649.
- Strous GJ, Dekker J: Mucin-type glycoproteins. Crit Rev Biochem MoI Biol 1992;27:57-92.
- Rose MC, Gendler SJ: Airway mucin genes and gene products. In Rogers DF, Lethem MI: eds. Airway Mucus: Basic Mechanisms and Clinical Perspectives. Boston: Birkhauser Verlag; 1997:41-66.
- Lapensee L, Paquette Y, Bleau G: Allelic polymorphism and chromosomal localization of the human oviductin gene (MUC9). Fertil Steril. 1997;68:702-708.
- Williams SJ, McGuckin MA, Gotley DC, Eyre HJ, Sutherland GR, Antalis TM: Two novel mucin genes down-regulated in colorectal cancer identified by differential display. Cancer Res. 1999;59:4083-4089.
- Hovenberg HW, Davies JR, Herrmann A, Linden CJ, Carlstedt I: MUC5AC, but not MUC2, is a prominent mucin in respiratory secretions. Glycoconj J. 1996;13:839-847.
- Wickstrom C, Davies JR, Eriksen GV, Veerman EC, Carlstedt I: MUC5B is a major gel-forming, oligomeric mucin from human salivary gland, respiratory tract and endocervix: identification of gtycoforms and C-terminal cleavage. Biochem J. 1998;334:685-693.
- Li D, Gallup M, Fan N, Szymkowski DE, Basbaum CB: Cloning of the amino-terminal and 5'-flanking region of the human MUC5AC mucin gene and transcriptional up-regulation by bacterial exoproducts. J Biol Chem. 1998;273:6812-6820.
- Li JD, Dohrman AF, Gallup M, Miyata S, Gum JR, Kim YS, Nadel JA, Prince A, Basbaum CB: Transcriptional activation of mucin by Pseudomonas aeruginosa lipopolysaccharide in the pathogenesis of cystic fibrosis lung disease. Proc Natl Acad Sei U S A. 1997;94:967-972.
- Levine SJ, Larivee P, Logun C, Angus CW, Ognibene FP, Shelhamer JH: Tumor necrosis factor-alpha induces mucin hypersecretion and MUC-2 gene expression by human airway epithelial cells. Am J Respir Cell MoI Biol 1995;12:196-204.
- Dohrman A, Miyata S, Gallup M, Li JD, Chapelin C, Coste A, Escudier E, Nadel J, Basbaum C: Mucin gene (MUC 2 and MUC 5AC) upregulation by gram-positive and gram-negative bacteria. Biochim Biophys Acte. 1998;1406:251-259.
- Horchers MT, Carly MP, Leikauf GD: Regulation of human airway mucins by acrolein and inflammatory mediators. Am J Physiol (Lung Cell MoI Physiol 20). 1999;276:L549-L555.
- VoynowJA, Young LR, Wang Y, Horgen T, Rose MC, Fischer BM: Neutrophil elastase increases MUC5AC mRNA and protein expression in respiratory epithelial cells. AmJ Physiol (Lung Cell MoI Physiol 20). 1999;276:L835-L843.
- Nettesheim P, Bader T: Tumor necrosis factor alpha stimulates arachidonic acid metabolisms and mucus production in rat tracheal epithelial cell cultures. Toxicol Lett 1996;88:35-37.
- Fischer BM, Rochelle LG, Voynow JA, Akley NJ, Adler KB: Tumor necrosis factor-alpha stimulates mucin secretion and cyclic GMP production by guina pig tracheal epithelial cells in vitro. Am J Respir Cell MoI Biol 1999;20:413-422.
- Kim KC, Wasano K, Niles RM, Schuster JE, Stone PJ, Brody JS: Human neutrophil elastase releases cell surface mucins from primary cultures of hamster trachal epithelial cells. Proc Natl Acad Sei USA. 1987;84:9304-9308.
- Cohan VL, Scott AL, Dinarello CA, Prendergast RA: Interleukin-1 is a mucus secretagogue. Cell ImmunoL 1991;136:425-434.
- Dinarello CA: Interleukin-1. Cytokine Growth Factor Rev. 1997;8:253-265.
- Broide DH, Lotz M, Cuomo AJ, Cobum DA, Federman EC, Wasserman SI: Cytokines in cymptomatic asthma airways. J Allergy Clin Immunol 1992;89:958-967.
- Tillie-Leblond I, Pugin J, Marquette CH, Lamblin C, Saulnier F, Brichet A, Wallaert B, Tonnel AB, Gsset P: Balance between proinflammatory cytokines and their inhibitors in bronchial lavage from patients with status asthmaticus. Am J Respir Crit Care Med. 1999;!59:487-494.
- Guzman K, Gray TE, Yoon JH, Nettesheim P: Quantitation of mucin RNA by PCR reveals induction of both MUC2 and MUC5AC mRNA levels by retinoids. AmJ Physiol (Lung Cell MoI Physiol 15). 1996:271;L1023-L1028.
- Yoon JH, Gray T, Guzman K, KooJS, Nettesheim P: Regulation of the secretory phenotype of human airway epithelium by retinoic acid, triiodothyronine, and extracellular matrix. Am J Respir Cell MoI Biol 1997;16:724-731.
- Koo JS, Yoon JH, Gray T, Norfbrd D Jetten AM, Nettesheim P: Restoration of the mucous phenotype by retinoic acid in retinoid-deficient human bronchial cell cultures. Changes in mucin gene expression. AmJ Respir Cell MoI Biol 1999;20:43-52.
- Koo JS, Jetten AM, Belloni P, Yoon JH, Kim YD, Nettesheim P: Role of retinoid receptors in the regulation of mucin gene expression by retinoic acid in human tracheobronchial epithelial cells. BiochemJ. 1999;338:351-357.
- Apfel C, Bauen F, Crettaz M, Forni L, Kamber M, Kaufmann F, LeMotte P, Pirson W, Klaus M: A retinoic acid receptor alpha antagonist selectively counteracts retinoic acid effects. Proc Nad Acad Sei U S A. 1992;89:7129-7133.
- Gum JR Jr, Hicks JW, Toribara NW, Siddiki B, Kim YS: Molecular cloning of human intestinal mucin (MUC2) cDNA Identification of the amino terminus and overall sequence similarity to prepro-von Willebrand factor. J Biol Chem. 1994;269:2440-2446.
- Meezaman D, Charles P, Daskal E, Polymeropoulos MH, Martin BM, Rose MC: Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5). J Biol Chem. 1994;269:12932-12939.
- Desseyn JL, AubertJP, Van Seuningen I, Porchet N, Laine A: Genomic organization of the 3' region of the human mucin gene MUC5B.J Biol Chem. 1997:272:16873-16883.
- Thornton DJ, Carlstedt I, Sheehan JK: Identification of glycoproteins on nitrocellulose membranes and gels. MoI Biotechnol. 1996;5:171-176.
- Winzen R, Kracht M, Ritten B, Wilhelm A, Chen CY, Shyu AB, Mullen M, Gaestel M, Resch K, Holtmann H: The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinaseactivated protein kinase 2 and an AU-rich region-targeted mechanism. EMBOJ. 1999;18:4969-4980.
- Roebuck KA: Regulation of interleukin-8 gene expression. J Interferon Cytokine Res. 1999;!9:429438.
- Levine SJ: Bronchial epithelial cell-cytokine interactions in airway inflammation. J Investig Med. 1995;43:241-249.
- Li JD, Feng W, Gallup M, Kim JH, Gum J, Kim Y, Basbaum C: Activation of NF-kappaB via a Srcdependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells. Proc Natl Acad Sei U S A. 1998;95:5718-5723.
- Louahed J, Toda M,Jen J, Hamid Q, Renauld JC, Levitt RC, Nicolaides NC: Interleukin-9 upregulates mucus expression in the airways. Am J Respir Cell MoI Biol 2000;22:649-656.
- Gray TE, Guzman K, Davis CW, Abdullah LH, Nettesheim P: Mucociliary differentiation of serially passaged normal human tracheobronchial epithelial cells. AmJ Respir Cell MoI Biol 1996;!4:104112.
- Velcich A, Palumbo L, Selleri L, Evans G, Augenlicht L Organization and regulatory aspects of the human intestinal mucin gene (MUC2) locus. J Biol Chem. 1997;272:7968-7976.
- Gum JR, Hicks JW, Kim YS: Identification and characterization of the MUC2 (human intestinal mucin) gene 5'-flanking region: promoter activity in cultured cells. Biochem J. 1997;325:259-267.
OVEREXPRESSION OF MUCIN GENES INDUCED BY INTERLEUKIN1-1β, TUMOR NECROSIS FACTOR-α, LIPOPOLYSACCHARIDE, AND NEUTROPHIL ELASTASE IS INHIBITED BY A RETINOIC ACID RECEPTOR α ANTAGONIST
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.