36
Views
24
CrossRef citations to date
0
Altmetric
Research Article

EFFECTS OF DELAYED TREATMENT WITH TRANSFORMING GROWTH FACTOR-β SOLUBLE RECEPTOR IN A THREE-DOSE BLEOMYCIN MODEL OF LUNG FIBROSIS IN HAMSTERS

, , &
Pages 405-417 | Published online: 02 Jul 2009

  • Weissler JC: Idiopathic pulmonary fibrosis cellular and molecular pathogenesis. Am J Med Sci. 1989;297:91-104.
  • Snider GL, Hayes JA, Korthy AL: Chronic interstitial pulmonary fibrosis produced in hamsters by endotracheal bleomycin: pathology and stereology. Am Rev Respir Dis. 1978; 117:1099-1108.
  • Coker RK, Laurent GJ: Pulmonary fibrosis: cytokines in the balance; Eur. Respir J. 1998;11:1218-1221.
  • Roberts AB, Sporn MB, Assoian RK, Smith JM, Roche NS, Wakefield LM, Heine UT, Liotta LA, Falanga V, Kehrl JH: Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Nad Mad Sci U S A. 1986;83:4167-4171.
  • Raghow R, Postlethwaite AB, Keski-Oja J, Moses HL, Rang AH: Transforming growth factor-beta increases steady state levels of type I procollagen and fibronectin messenger RNAs posttranscriptionally in cultured human dermal fibroblasts. J Chin Invest 1987;79;1285-1288.
  • Raghow R, Lurie S, Seyer JM, Rang AH: Profiles of steady state levels of messenger RNAs coding for type I procollagen, elastin, and fibronectin in hamster lungs undergoing bleomycin-induced interstitial pulmonary fibrosis. J Chin Invest 1985;76:1733-1739.
  • Gurujeyalakshmi G, Hollinger MA, Giri SN: Regulation of transforming growth factor-betal mRNA expression by taurine and niacin in the bleomycin hamster model of lung fibrosis. Am J Respir Cell Mol. Biol. 1998;18:334-342.
  • Wang Q, Wang Y, Hyde DM, Gotwals PJ, Koteliansky VE, Ryan ST, Giri SN: Reduction of bleomycin induced lung fibrosis by transforming growth factor beta soluble receptor in hamsters. Thorax. 1999;54:805-812.
  • Zia S, Hyde DM, Giri SN: Development of a bleomycin hamster model of subchronic lung fibrosis. Pathology. 1992:24:155-163.
  • Wang Q, Giri SN, Hyde DM, Li C: Amelioration of bleomycin-induced pulmonary fibrosis in hamsters by combined treatment with taurine and niacin. Biochem Pharmacol. 1991;42: 1115-1122.
  • Iyer SN, Margolin SB, Hyde DM, Giri S N: Lung fibrosis is ameliorated by pirfenidone in diet after the second dose in a three-dose bleomycin hamster model Exp Lung Res. 1998;24:119-132.
  • Zheng H, Wang J, Koteliansky VE, Gotwals PJ, Hauerjensen M: Recombinant soluble transforming growth factor beta type II receptor ameliorates radiation enteropathy in mice. Gastroenterology. 2000:119:1286-1296.
  • Ohkawa H, Ohishi N, Yagi K: Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979;95:351-358.
  • Woessner JFJ: The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Arch Biochem Biophys. 1961;93:440-447.
  • Giri SN, Misra HP, Chandler DB, Chen Z: Increases in lung prolyl. hydroxylase and Superoxide dismutase activities during bleomycin-induced lung fibrosis in hamsters. Exp Mol Pathol. 1983;39:317-326.
  • Karlinski JB, Goldstein CH: Fibritic lung diseases: a perspective. J Lab Chin Med. 1980;96:939-942.
  • Gross TJ, Hunninghake GW: Idiopathic pulmonary fibrosis. N Engl J Med. 2001;345:517-525.
  • Shahib FS, Andoh TF, Tanner AM, Noble NA, Border WA, Frenceschini BWM: Role of transforming growth factor-ß in experimental chronic cyclosporin nephropathy. Kidney Int. 1996;49:1141-1151.
  • Iyer SN. Gurujeyalakshmi G, Giri SN: Effects of pirfenidone on transforming growth factor-ß gene expression at the transcriptiona level in bleomycin hamster model of lung fibrosis. J. Pharmacol Exp Ther. 1999;291;367-373.
  • Yamamoto T, Noble NA, Cohn AH, Nast CD, Hisida A, Gold LI, Border WA: Expression of transforming growth factor-ß isofbrms in human glomerular diseases. Kidney int. 1996;49:461-469.
  • Broeckelmann TJ, Limper AH, Colby TB, McDonald JA: Transforming growth factor-ß is present at site of extracellular matrix gene expression in human pulmonary fibrosis. Proc Natl Acad Sci U S A 1991;88:6642-6646.
  • Khalil N, O'Conner RN, Unrut MW, Warren PW, Flanders KC, Kemp A, Berenzay OH, Green AH: Increased production and immunochemical localization of transforming growth factor-ß in idiopathic pulmonary fibrosis. Am J Respir Cell Mol Biol. 1991;5:155-162.
  • Bruijn IA, Roos A, deGues B, deHeer E: Transforming growth factor-ß and the glomerular extracellular matrix in renal pathology. J Lab Chin Med. 1994;123:34-47.
  • Edward DR, Murphy G, Reynohd JJ, Whiteman SC, Docherty JP, Angel P, Heath JK: TGF-ß modulates the expression of collagenase and metalloproteinase inhibitor. EMBO J. 1987;6:1899-1904.
  • Sporn MB, Roberts AB, Wakefield LM, Crombrugghe B: Some recent advances in the chemistry and biology of transforming growth facotr-ß J Cell Biol. 1987;105:1039-1045.
  • Giri SN, Hyde DM, Hollinger MA: Effect of antibody to transforming growth factor beta on bleomycin induced accumulation of lung collagen in mice. Thorax. 1993;48:959-966.
  • Giri SN, Hyde DM, Braun, RK, Gaarde W, Harper JR, Pierschbacher MD: Antifibrotic effect of decorin in a bleomycin hamster model of lung fibrosis. Biochem PharmacoL 1997;54:1205-1216.
  • Sugigura Y, Kikuchi T: Formation of Superoxide and hydroxy radicals in iron (n)-bleomycin-oxygen system: electron spin resonance detection by spin trapping. J Antibiot (Tokyo).1978;31:1310-1312
  • MacDonald GA, Bridle KR, Ward PJ, Walker NI, Houglum K, George DK, Smith JL, Powell LW, Crawford DH, Ramm GA: Lipid peroxidation in hepatic steatosis in humans is associated with hepatic fibrosis and occurs predominately in acinar zone 3. J Gastroenterol Hepatol. 2001;16:599-606.
  • Kawaguchi Y, Kitani A, Hara M, Harigai M, Hirose T, Suzuki K, Kawakami M, Hidaka Ishizuka T, Kawagoe M: Cytokine regulation of prolyl 4-hydroxylase production in skin fibroblast cultures from patients with systemic sclerosis: contribution to collagen synthesis and fibrosis. J Rheumatol. 1992;19:1195-1201.
  • Miller RL, Udenfriend S: Hydroxylation of proline residues in collagen nascent chains. Arch Biochem Biophys. 1970;139:104-113.
  • Kulkarni AB, Huh CG, Becker D, Geiser A, Lyght M, Flanders KC, Roberts AB, Sporn MB, Ward JM, Karlsson S: Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. Proc Nad Acad Sci U S A. 1993;90:770-774.
  • Clark DA, Goker R: Transforming growth factor-beta (TGF-beta). Int J Biochem Cell Biol. 1998;30:293-298.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.