ELEVATED ENDOGENOUS SURFACTANT REDUCES INFLAMMATION IN AN ACUTE LUNG INJURY MODEL

REFERENCES

• Bernard G R, Artigas A, Brigham K L, Carlet J, Falke K, Hudson L, Lamy M, Legall J R, Morris A, Spragg R, the Consensus Committee. The American-European consensus conference on ARDS: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 1994; 149: 818–824
   PubMed Web of Science ®Google Scholar
• Rubenfeld G D. Epidemiology of acute lung injury. Crit Care Med 2003; 31: S276–S284
   PubMed Web of Science ®Google Scholar
• Rubenfeld G D, Caldwell E, Peabody E, Weaver J, Martin D P, Neff M, Stern E J, Hudson L D. Incidence and outcomes of acute lung injury. N Engl J Med 2005; 353: 1685–1693
   PubMed Web of Science ®Google Scholar
• Montgomery A B, Stager M A, Carrico C J, Hudson E D. Causes of mortality in patients with the adult respiratory distress syndrome. Am Rev Respir Dis 1985; 132: 485–489
   PubMed Web of Science ®Google Scholar
• Wright J R. Immunomodulatory functions of surfactant. Physiol Rev 1997; 77: 931–962
   PubMed Web of Science ®Google Scholar
• Goerke J. Pulmonary surfactant: functions and molecular composition. Biochim Biophys Acta 1998; 1408: 79–89
   PubMed Web of Science ®Google Scholar
• Borron P, McIntosh J C, Korfhagen T R, Whitsett J A, Taylor J, Wright J R. Surfactant-associated protein A inhibits LPS-induced cytokine and nitric oxide production in vivo. Am J Physiol Lung Cell Mol Physiol 2000; 278: L840–L847
   PubMed Web of Science ®Google Scholar
• van Iwaarden F, Welmers B, Verhoef J, Haagsman H P, Van Golde L M. Pulmonary surfactant protein A enhances the host-defense mechanism of rat alveolar macrophages. Am J Respir Cell Mol Biol 1990; 2: 91–98
   PubMed Web of Science ®Google Scholar
• LeVine A M, Hartshorn K, Elliott J, Whitsett J, Korfhagen T. Absence of SP-A modulates innate and adaptive defense responses to pulmonary influenza infection. Am J Physiol Lung Cell Mol Physiol 2002; 282: L563–L572
   PubMed Web of Science ®Google Scholar
• Gunther A, Siebert C, Schmidt R, Ziegler S, Grimminger F, Yabut M, Temmesfeld B, Walmrath D, Morr H, Seeger W. Surfactant alterations in severe pneumonia, acute respiratory distress syndrome, and cardiogenic lung edema. Am J Respir Crit Care Med 1996; 153: 176–184
   PubMed Web of Science ®Google Scholar
• Gregory T J, Longmore W J, Moxley M A, Whitsett J A, Reed C R, Fowler A A, Maunder R J, Crim C, Hyers T M. Surfactant chemical composition and biophysical activity in acute respiratory distress syndrome. J Clin Invest 1991; 88: 1976–1981
   PubMed Web of Science ®Google Scholar
• Forbes A, Pickell M, Foroughian M, Yao L J, Lewis J, Veldhuizen R. Alveolar macrophage depletion is associated with increased surfactant pool sizes in adult rats. J Appl Physiol 2007; 103: 637–645
   PubMed Web of Science ®Google Scholar
• Lewis J F, Veldhuizen R A. The Future of Surfactant Therapy during ALI/ARDS. Semin Respir Crit Care Med 2006; 27: 377–388
   PubMed Web of Science ®Google Scholar
• Yamashita C, Forbes A, Tessolini J M, Yao L J, Lewis J F, Veldhuizen R A. Protective effects of elevated endogenous surfactant pools to injurious mechanical ventilation. Am J Physiol Lung Cell Mol Physiol 2008; 294: L724–L732
   PubMed Web of Science ®Google Scholar
• Van Rooijen N. The liposome-mediated macrophage ‘suicide’ technique. J Immunol Methods 1989; 124: 1–6
   PubMed Web of Science ®Google Scholar
• von Bethmann A N, Brasch F, Nusing R, Vogt K, Volk H D, Muller K M, Wendel A, Uhlig S. Hyperventilation induces release of cytokines from perfused mouse lung. Am J Respir Crit Care Med 1998; 157: 263–72
   PubMed Web of Science ®Google Scholar
• Veldhuizen R AW, Slutsky A S, Joseph M, McCaig L. Effects of mechanical ventilation of isolated mouse lungs on pulmonary surfactant and inflammatory cytokines. Eur Respir J 2001; 17: 488–494
   PubMed Web of Science ®Google Scholar
• Bligh E G, Dyer W J. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959; 37: 911–917
   PubMedGoogle Scholar
• Duck-Chong C G. A rapid sensitive method for determining phospholipid phosphorus involving digestion with magnesium nitrate. Lipids 1979; 14: 492–497
   Web of Science ®Google Scholar
• Van Rooijen N, Sanders A. Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J Immunol Methods 1994; 174: 83–93
   PubMed Web of Science ®Google Scholar
• Livingston D H, Mosenthal A C, Deitch E A. Sepsis and multiple organ dysfunction syndrome: a clinical- mechanistic overview. New Horiz 1995; 3: 257–264
   PubMedGoogle Scholar
• Slutsky A S, Tremblay L N. Multi system organ failure: is mechanical ventilation a contributing factor?. Am J Respir Crit Care Med 1998; 157: 1721–1725
   PubMed Web of Science ®Google Scholar
• Tremblay L, Valenza F, Ribeiro S P, Li J, Slutsky A S. Injurious ventilatory strategies increase cytokines and c-fos m- RNA expression in an isolated rat lung model. J Clin Invest 1997; 99: 944–952
   PubMed Web of Science ®Google Scholar
• Wrigge H, Zinserling J, Stuber F, von Spiegel T, Hering R, Wetegrove S, Hoeft A, Putensen C. Effects of mechanical ventilation on release of cytokines into systemic circulation in patients with normal pulmonary function. Anesthesiology 2000; 93: 1413–1417
   PubMed Web of Science ®Google Scholar
• Roumen R M, Hendriks T, van der Ven-Jongekrijg J, Nieuwenhuijzen G A, Sauerwein R W, van der Meer J W, Goris R J. Cytokine patterns in patients after major vascular surgery, hemorrhagic shock, and severe blunt trauma. Relation with subsequent adult respiratory distress syndrome and multiple organ failure. Ann Surg 1993; 218: 769–776
   PubMed Web of Science ®Google Scholar
• Dos Santos C C, Slutsky A S. The contribution of biophysical lung injury to the development of biotrauma. Annu Rev Physiol 2006; 68: 585–618
   PubMed Web of Science ®Google Scholar
• Tremblay L N, Slutsky A S. Ventilator-induced injury: from barotrauma to biotrauma. Proc Assoc Am Physicians 1998; 110: 482–488
   PubMedGoogle Scholar
• LeVine A M, Whitsett J A. Pulmonary collectins and innate host defense of the lung. Microbes Infect 2001; 3: 161–166
   PubMed Web of Science ®Google Scholar
• Van Iwaarden J F, Pikaar J C, Storm J, Brouwer E, Verhoef J, Oosting R S, Van Golde L MG, Van Strijp J AG. Binding of surfactant protein A to the lipid A moiety of bacterial lipopolysaccharides. Biochem J 1994; 303: 407–411
   PubMed Web of Science ®Google Scholar
• Veldhuizen R A, Welk B, Harbottle R, Hearn S, Nag K, Petersen N, Possmayer F. Mechanical ventilation of isolated rat lungs changes the structure and biophysical properties of surfactant. J Appl Physiol 2002; 92: 1169–1175
   PubMed Web of Science ®Google Scholar
• Verbrugge S J, Bohm S H, Gommers D, Zimmermann L J, Lachmann B. Surfactant impairment after mechanical ventilation with large alveolar surface area changes and effects of positive end-expiratory pressure. Br J Anaesth 1998; 80: 360–364
   PubMed Web of Science ®Google Scholar
• Brower R G, Matthay M A, Morris A, Schoenfeld D, Thompson B T, Wheeler A. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 2000; 342: 1301–1308
   PubMed Web of Science ®Google Scholar
• Delclaux C, Rezaiguia-Delclaux S, Delacourt C, Brun-Buisson C, Lafuma C, Harf A. Alveolar neutrophils in endotoxin-induced and bacteria-induced acute lung injury in rats. Am J Physiol 1997; 273: L104–L112
   PubMed Web of Science ®Google Scholar