TSLP promotes asthmatic airway remodeling via p38-STAT3 signaling pathway in human lung fibroblast

References

• Hwang JC, Kim JH, Kim JH, et al. Endoscopic resection for the treatment of gastric subepithelial tumors originated from the muscularis propria layer. Hepato-gastroenterology 2009;56:1281–1286.
   PubMed Web of Science ®Google Scholar
• Al-Muhsen S, Johnson JR, Hamid Q. Remodeling in asthma. J Allergy Clin Immunol. 2011;128(3):451–462. quiz 463–454.
   PubMed Web of Science ®Google Scholar
• Brightling CE, Gupta S, Gonem S, Siddiqui S. Lung damage and airway remodelling in severe asthma. Clin Exp Allergy. 2012;42(5):638–649.
   PubMed Web of Science ®Google Scholar
• He R, Geha RS. Thymic stromal lymphopoietin. Ann N Y Acad Sci. 2010;1183:13–24.
   PubMed Web of Science ®Google Scholar
• Wang Q, Du J, Zhu J, Yang X, Zhou B. Thymic stromal lymphopoietin signaling in CD4(+) T cells is required for TH2 memory. J Allergy Clin Immunol. 2015;135(3):781–791.e783.
   PubMed Web of Science ®Google Scholar
• Watson B, Gauvreau GM. Thymic stromal lymphopoietin: a central regulator of allergic asthma. Exp Opin Therap Targets. 2014;18(7):771–785.
   PubMed Web of Science ®Google Scholar
• Shikotra A, Choy DF, Ohri CM, et al. Increased expression of immunoreactive thymic stromal lymphopoietin in patients with severe asthma. J Allergy Clin Immunol. 2012;129(1):104–111.
   PubMed Web of Science ®Google Scholar
• Ying S, O'Connor B, Ratoff J, et al. Expression and cellular provenance of thymic stromal lymphopoietin and chemokines in patients with severe asthma and chronic obstructive pulmonary disease. J Immunol. 2008;181(4):2790–2798.
   PubMed Web of Science ®Google Scholar
• Chauhan A, Singh M, Agarwal A, Paul N. Correlation of TSLP, IL-33, and CD4 + CD25 + FOXP3 + T regulatory (Treg) in pediatric asthma. J Asthma. 2015;52(9):868–872.
   PubMed Web of Science ®Google Scholar
• Pearson G, Robinson F, Beers Gibson T, et al. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev. 2001;22(2):153–183.
   PubMed Web of Science ®Google Scholar
• Heijink IH, Nawijn MC, Hackett TL. Airway epithelial barrier function regulates the pathogenesis of allergic asthma. Clin Exp Allergy. 2014;44(5):620–630.
   PubMed Web of Science ®Google Scholar
• Woodruff PG, Dolganov GM, Ferrando RE, et al. Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression. Am J Respir Crit Care Med. 2004;169(9):1001–1006.
   PubMed Web of Science ®Google Scholar
• Redhu NS, Shan L, Al-Subait D, et al. IgE induces proliferation in human airway smooth muscle cells: role of MAPK and STAT3 pathways. Allergy Asthma Clin Immunol. 2013;9(1):41.
   PubMed Web of Science ®Google Scholar
• Wu J, Liu F, Zhao J, et al. Thymic stromal lymphopoietin promotes asthmatic airway remodelling in human lung fibroblast cells through STAT3 signalling pathway. Cell Biochem Funct. 2013;31(6):496–503.
   PubMed Web of Science ®Google Scholar
• Levy DE, Darnell JE. Jr., Stats: transcriptional control and biological impact. Nat Rev Mol Cell Biol. 2002;3(9):651–662.
   PubMed Web of Science ®Google Scholar
• Kida H, Mucenski ML, Thitoff AR, et al. GP130-STAT3 regulates epithelial cell migration and is required for repair of the bronchiolar epithelium. Am J Pathol. 2008;172(6):1542–1554.
   PubMed Web of Science ®Google Scholar
• Nagahama KY, Togo S, Holz O, et al. Oncostatin M modulates fibroblast function via signal transducers and activators of transcription proteins-3. Am J Respir Cell Mol Biol. 2013;49(4):582–591.
   PubMed Web of Science ®Google Scholar
• Desai P, Yang J, Tian B, et al. Mixed-effects model of epithelial-mesenchymal transition reveals rewiring of signaling networks. Cell Signal. 2015;27(7):1413–1425.
   PubMed Web of Science ®Google Scholar
• Liu DS, Wang T, Han SX, et al. p38 MAPK and MMP-9 cooperatively regulate mucus overproduction in mice exposed to acrolein fog. Int Immunopharmacol. 2009;9(10):1228–1235.
   PubMed Web of Science ®Google Scholar
• Wang Q, Li H, Yao Y, et al. HB-EGF-promoted airway smooth muscle cells and their progenitor migration contribute to airway smooth muscle remodeling in asthmatic mouse. J Immunol. 2016;196(5):2361–2367.
   PubMed Web of Science ®Google Scholar
• Itoigawa Y, Harada N, Harada S, et al. TWEAK enhances TGF-beta-induced epithelial-mesenchymal transition in human bronchial epithelial cells. Respir Res. 2015;16:48.
   PubMed Web of Science ®Google Scholar
• Sabatini F, Luppi F, Petecchia L, et al. Bradykinin-induced asthmatic fibroblast/myofibroblast activities via bradykinin B2 receptor and different MAPK pathways. Eur J Pharmacol. 2013;710(1–3):100–109.
   PubMed Web of Science ®Google Scholar
• Conte E, Gili E, Fagone E, Fruciano M, Iemmolo M, Vancheri C. Effect of pirfenidone on proliferation, TGF-beta-induced myofibroblast differentiation and fibrogenic activity of primary human lung fibroblasts. Eur J Pharm Sci. 2014;58:13–19.
   PubMed Web of Science ®Google Scholar
• Bernard K, Logsdon NJ, Ravi S, et al. Metabolic reprogramming is required for myofibroblast contractility and differentiation. J Biol Chem. 2015;290(42):25427–25438.
   PubMed Web of Science ®Google Scholar
• Alkhouri H, Poppinga WJ, Tania NP, Ammit A, Schuliga M. Regulation of pulmonary inflammation by mesenchymal cells. Pulm Pharmacol Ther. 2014;29(2):156–165.
   PubMed Web of Science ®Google Scholar
• Li D, Chen D, Zhang X, et al. c-Jun N-terminal kinase and Akt signalling pathways regulating tumour necrosis factor-alpha-induced interleukin-32 expression in human lung fibroblasts: implications in airway inflammation. Immunology 2015;144(2):282–290.
   PubMed Web of Science ®Google Scholar
• Sun Q, Liu L, Mandal J, et al. PDGF-BB induces PRMT1 expression through ERK1/2 dependent STAT1 activation and regulates remodeling in primary human lung fibroblasts. Cell Signal. 2016;28(4):307–315.
   PubMed Web of Science ®Google Scholar
• Zhang K, Shan L, Rahman MS, Unruh H, Halayko AJ, Gounni AS. Constitutive and inducible thymic stromal lymphopoietin expression in human airway smooth muscle cells: role in chronic obstructive pulmonary disease. Am J Physiol: Lung Cell Mol Physiol. 2007;293(2):L375–L382.
   PubMed Web of Science ®Google Scholar
• Liang Y, Hou C, Kong J, et al. HMGB1 binding to receptor for advanced glycation end products enhances inflammatory responses of human bronchial epithelial cells by activating p38 MAPK and ERK1/2. Mol Cell Biochem. 2015;405(1–2):63–71.
   PubMed Web of Science ®Google Scholar
• Yamauchi K, Inoue H. Airway remodeling in asthma and irreversible airflow limitation-ECM deposition in airway and possible therapy for remodeling. Allergol Int: Off J Jap Soc Allergol. 2007;56(4):321–329.
   PubMedGoogle Scholar